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In this paper we study the effective degrees of freedom of a general class of reduced rank estimators for multivariate regression in the framework of Stein's unbiased risk estimation (SURE). We derive a finite-sample exact unbiased estimator that admits a closed-form expression in terms of the singular values or thresholded singular values of the least squares solution and hence readily computable. The results continue to hold in the high-dimensional scenario when both the predictor and response dimensions are allowed to be larger than the sample size. The derived analytical form facilitates the investigation of its theoretical properties and provides new insights into the empirical behaviors of the degrees of freedom. In particular, we examine the differences and connections between the proposed estimator and a commonly-used naive estimator, i.e., the number of free parameters. The use of the proposed estimator leads to efficient and accurate prediction risk estimation and model selection, as demonstrated by simulation studies and a data example., Comment: 29 pages, 3 figures

In longitudinal and spatial studies, observations often demonstrate strong correlations that are stationary in time or distance lags, and the times or locations of these data being sampled may not be homogeneous. We propose a nonparametric estimator of the correlation function in such data, using kernel methods. We develop a pointwise asymptotic normal distribution for the proposed estimator, when the number of subjects is fixed and the number of vectors or functions within each subject goes to infinity. Based on the asymptotic theory, we propose a weighted block bootstrapping method for making inferences about the correlation function, where the weights account for the inhomogeneity of the distribution of the times or locations. The method is applied to a data set from a colon carcinogenesis study, in which colonic crypts were sampled from a piece of colon segment from each of the 12 rats in the experiment and the expression level of p27, an important cell cycle protein, was then measured for each cell within the sampled crypts. A simulation study is also provided to illustrate the numerical performance of the proposed method., Comment: Published in at http://dx.doi.org/10.1214/009053607000000082 the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org)