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The breaking of immune tolerance against autologous angiogenic endothelial cells should be a useful approach for cancer therapy. Here we show that immunotherapy of tumors using fixed xenogeneic whole endothelial cells as a vaccine was effective in affording protection from tumor growth, inducing regression of established tumors and prolonging survival of tumor-bearing mice. Furthermore, autoreactive immunity targeting to microvessels in solid tumors was induced and was probably responsible for the anti-tumor activity. These observations may provide a new vaccine strategy for cancer therapy through the induction of an autoimmune response against the tumor endothelium in a cross-reaction., Author(s): Yu-quan Wei (corresponding author) [1]; Qing-ru Wang [1]; Xia Zhao [2]; Li Yang [1]; Ling Tian [1]; You Lu [1]; Bin Kang [1]; Chong-jiu Lu [1]; Mei-juan Huang [1]; [...]

The article discusses the qualities of partial * - λ -semirings which proved that all n x n upper triangular matrix in partial semirings in each n ≥ 0 S are * - λ -semirings.

To study the inductive -semirings and weak inductive * -semirings more deeply, UF-inductive -semirings and UF-weak inductive -semirings are defined. Some qualities of them are given. The relationships among these semirings are discussed. Also, the formal power series semirings and the matrices semirings over UF-inductive -semirings and UF-weak inductive * -semirings are researched and some results are obtained. The results are the generalization of the known theorem of the -semirings. [ABSTRACT FROM AUTHOR]