37 results on '"Wang, Tammy C."'
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2. Oral Delivery of Highly Lipophilic, Poorly Water-Soluble Drugs: Self-Emulsifying Drug Delivery Systems to Improve Oral Absorption and Enable High-Dose Toxicology Studies of a Cholesteryl Ester Transfer Protein Inhibitor in Preclinical Species
3. Exploration of macrocyclic peptide binders to the extracellular CRD domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1)
4. Discovery of a Lead Triphenylethanamine Cholesterol Ester Transfer Protein (CETP) Inhibitor
5. Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors
6. Microwave-assisted transamidation of ureas
7. Synthesis of Fmoc-Protected Arylphenylalanines (Bip Derivatives) via Nonaqueous Suzuki-Miyaura Cross-Coupling Reactions
8. 2-Amino-1,3,4-thiadiazoles in the 7-hydroxy-N-neopentyl spiropiperidine indolinyl series as potent P2Y1 receptor antagonists
9. Identification of 1-{2-[4-chloro-1′-(2,2-dimethylpropyl)-7-hydroxy-1,2-dihydrospiro[indole-3,4′-piperidine]-1-yl]phenyl}-3-{5-chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl}urea, a potent, efficacious and orally bioavailable P2Y1 antagonist as an antiplatelet agent
10. Discovery of diarylurea P2Y1 antagonists with improved aqueous solubility
11. ChemInform Abstract: Microwave-Assisted Transamidation of Ureas.
12. Triphenylethanamine Derivatives as Cholesteryl Ester Transfer Protein Inhibitors: Discovery of N-[(1R)-1-(3-Cyclopropoxy-4-fluorophenyl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-4-fluoro-3-(trifluoromethyl)benzamide (BMS-795311)
13. Discovery of 4-Aryl-7-Hydroxyindoline-Based P2Y1 Antagonists as Novel Antiplatelet Agents
14. 4-Benzothiazole-7-hydroxyindolinyl Diaryl Ureas Are Potent P2Y1Antagonists with Favorable Pharmacokinetics: Low Clearance and Small Volume of Distribution
15. Conformationally Constrained ortho-Anilino Diaryl Ureas: Discovery of 1-(2-(1′-Neopentylspiro[indoline-3,4′-piperidine]-1-yl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea, a Potent, Selective, and Bioavailable P2Y1 Antagonist
16. 2-Arylbenzoxazoles as novel cholesteryl ester transfer protein inhibitors: Optimization via array synthesis
17. Diphenylpyridylethanamine (DPPE) Derivatives as Cholesteryl Ester Transfer Protein (CETP) Inhibitors
18. ChemInform Abstract: Transformation of Anionically Activated Trifluoromethyl Groups to Heterocycles under Mild Aqueous Conditions.
19. Transformation of Anionically Activated Trifluoromethyl Groups to Heterocycles under Mild Aqueous Conditions
20. ChemInform Abstract: A General Synthesis of Dioxolenone Prodrug Moieties.
21. SAR and X-ray structures of enantiopure 1,2-cis-(1R,2S)-cyclopentyldiamine and cyclohexyldiamine derivatives as inhibitors of coagulation Factor Xa
22. Enantiopure five-membered cyclicdiamine derivatives as potent and selective inhibitors of factor Xa. Improving in vitro metabolic stability via core modifications
23. 4-Benzothiazole-7-hydroxyindolinyl Diaryl Ureas Are Potent P2Y1 Antagonists with Favorable Pharmacokinetics: Low Clearance and Small Volume of Distribution.
24. Discovery of Potent, Orally-Active, and Muscle-Selective Androgen Receptor Modulators Based on an N-Aryl-hydroxybicyclohydantoin Scaffold
25. Retro-Binding thrombin active site inhibitors: identification of an orally active inhibitor of thrombin catalytic activity
26. ChemInform Abstract: Thrombin Active Site Inhibitors: Chemical Synthesis, in vitro and in vivo Pharmacological Profile of a Novel and Selective Agent BMS‐189090 and Analogues.
27. A general synthesis of dioxolenone prodrug moieties
28. Thrombin active site inhibitors: chemical synthesis, in vitro and in vivo pharmacological profile of a novel and selective agent BMS-189090 and analogues
29. Discovery of 4-Aryl-7-Hydroxyindoline-Based P2Y1Antagonists as NovelAntiplatelet Agents.
30. Conformationally Constrained ortho-Anilino Diaryl Ureas: Discovery of 1-(2-(1′-Neopentylspiro[indoline-3,4′-piperidine]-1-yl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea,a Potent, Selective, and Bioavailable P2Y1Antagonist.
31. Structure of a Retro-binding Peptide Inhibitor Complexed with Human α-Thrombin
32. Discovery of diarylurea P2Y1 antagonists with improved aqueous solubility.
33. Diphenylpyridylethanamine(DPPE) Derivatives as Cholesteryl Ester Transfer Protein (CETP) Inhibitors.
34. ChemInform Abstract: A General Synthesis of Dioxolenone Prodrug Moieties.
35. 2-Amino-1,3,4-thiadiazoles in the 7-hydroxy-N-neopentyl spiropiperidine indolinyl series as potent P2Y1 receptor antagonists.
36. Identification of 1-{2-[4-chloro-1′-(2,2-dimethylpropyl)-7-hydroxy-1,2-dihydrospiro[indole-3,4′-piperidine]-1-yl]phenyl}-3-{5-chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl}urea, a potent, efficacious and orally bioavailable P2Y1 antagonist as an antiplatelet agent.
37. 4-Benzothiazole-7-hydroxyindolinyl diaryl ureas are potent P2Y1 antagonists with favorable pharmacokinetics: low clearance and small volume of distribution.
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