Search

Your search keyword '"Wang, Xue-Chao"' showing total 176 results
Start Over Author "Wang, Xue-Chao"
176 results on '"Wang, Xue-Chao"'

43. Design and synthesis of chiral ketones for catalytic asymmetric epoxidation of unfunctionalized olefins

Author

Dan Yang, Wong, Man-Kim, Yip, Yiu-Chung, Wang, Xue-Chao, Tang, Man-Wai, Zheng, Jian-Hua, and Cheung, Kung-Kai

Subjects
Chirality -- Research, Ketones -- Research, Epoxy compounds -- Research, Chemistry
Abstract

The synthesis of a series of novel C2 symmetrical chiral ketones and their activities in catalytic asymmetric epoxidations are described. The first cyclic ketone obtained from the process acted as the ideal template for the introduction of chiral elements. Results also showed that the ester groups that provide rigid and C2 symmetric structures to the cyclic ketones significantly influence the effectiveness of asymmetric epoxidations.

Published
1998

44. Clinical efficacy of ticagrelor in patients undergoing emergency intervention for acute myocardial infarction and its impact on platelet aggregation rate

Author

Wu, Hai-Bo, Tian, Huan-Ping, Wang, Xue-Chao, Bai, Shi-Ru, Li, Xin-Ning, Zhang, Li-Na, and Du, Rong-Pin

Subjects
Original Article, cardiovascular diseases
Abstract

Objective: This study aims to investigate the clinical efficacy of ticagrelor in patients who underwent emergency percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI), and its impact on platelet aggregation rate. Methods: A total of 257 AMI patients who underwent emergency PCI in our hospital were included in the present study. These patients were randomly divided into two groups: ticagrelor group (n = 129), patients took 180 mg of ticagrelor (qd) before the intervention, and subsequently took 90 mg of ticagrelor (bid) for maintenance; clopidogrel group (n = 128), patients took 300 mg of clopidogrel (qd) before PCI, and subsequently took 75 mg of clopidogrel (qd) for maintenance. Patients in both groups took 100 mg of aspirin. The major adverse cardiovascular events (MACE) within one year, changes in LVEF and LVEDD, platelet aggregation rate and drug safety before PCI and at one week and 30 days after PCI were observed in these two groups. Results: The differences in baseline data between these two groups were not statistically significant. Within one year after the intervention, in the ticagrelor group, the total incidence of MACE was lower (P < 0.05), LVEF and LVEDD was improved (P < 0.05), and the decrease in platelet aggregation rate after the intervention was more significant (P < 0.05). Furthermore, the incidence of bleeding events was higher in the ticagrelor group than in the clopidogrel group (P < 0.05). Conclusions: Compared with clopidogrel, ticagrelor decreases the incidence of adverse cardiovascular events in AMI patients who underwent emergency PCI, does better in improving the fluctuation level of LVEF and LVEDD, and strongly inhibits platelet aggregation. Some patients encountered adverse drug events, but drug withdrawal or medication change did not occur.

Published
2018

48. Rainfall-runoff forecast method based on GIS

Author

Zhou Zhen-min, Zhou Ke, and Wang Xue-chao

Subjects
Geographic information system, Meteorology, Artificial neural network, business.industry, Weather forecasting, Geodetic datum, Structural basin, computer.software_genre, Runoff model, Environmental science, Dependability, business, Vflo, computer
Abstract

Firstly, the different factors in the hydrological process and information treatment were analyzed. Secondly, application of the neural networks model with the basis of genetic Algorithms were studied. Thirdly, based on GIS map, the basin rainfall runoff forecast method was put forward. Through GIS rainfall information treatment, the precision of input datum to the rainfall runoff model was improved. Finally, through example analysis, the dependability and efficiency of the method application in rainfall runoff forecast was examined.

Published
2011

49. Water environment evaluation based on fuzzy comprehensive method

Author

Zhou Zhen-min, Wang Xue-chao, and Zhou Ke

Subjects
Pollutant, Water resources, Water conservation, Risk analysis (engineering), Computer science, Fuzzy set, Water environment, Environmental engineering, Dependability, Water quality, Fuzzy logic
Abstract

There are a lot of factors to influence water environment evaluation. The mutual-effect is very complex. In order to reflect clearly the effects of different factors in water environment evaluation, the paper adopted fuzzy comprehensive evaluation method to deal with water environment. It is shown from study results that the fuzzy comprehensive method has good dependability for water environment evaluation. The method can calculate the main pollutants, provide data for reasonable water environment management and play reference role in other methods used in water environment evaluation.

Published
2011

Catalog

Books, media, physical & digital resources
See catalog results