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454 results on '"Wang, Xue-Qin"'

11. Challenges and Suggestions of Ethical Review on Clinical Research Involving Brain-Computer Interfaces.

Author

Wang, Xue-Qin, Sun, Hong-Qiang, Si, Jia-Yue, Lin, Zi-Yan, Zhai, Xiao-Mei, and Lu, Lin

Abstract

Brain-computer interface (BCI) technology is rapidly advancing in medical research and application. As an emerging biomedical engineering technology, it has garnered significant attention in the clinical research of brain disease diagnosis and treatment, neurological rehabilitation, and mental health. However, BCI also raises several challenges and ethical concerns in clinical research. In this article, the authors investigate and discuss three aspects of BCI in medicine and healthcare: the state of international ethical governance, multidimensional ethical challenges pertaining to BCI in clinical research, and suggestive concerns for ethical review. Despite the great potential of frontier BCI research and development in the field of medical care, the ethical challenges induced by itself and the complexities of clinical research and brain function have put forward new special fields for ethics in BCI. To ensure "responsible innovation" in BCI research in healthcare and medicine, the creation of an ethical global governance framework and system, along with special guidelines for cutting-edge BCI research in medicine, is suggested. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Bioinformatic analysis of systemic lupus erythematosus based on miRNA microarray

Author

KONG Jie, GAO Ying-ying, WANG Xue-qin

Subjects
systemic lupus erythematosus, bioinformatic analysis, dendritic cells, mirna, Medicine
Abstract

Objective To analyze the differential expressions of miRNA in monocyte derived dendritic cells (moDCs) from systemic lupus erythematosus (SLE) patients and healthy people by bioinformatic analysis. Methods The GSE79240 dataset was downloaded from the gene expression omnibus (GEO) database, differential miRNAs were screened by R language. Funrich software was used to analyze the gene ontology (GO) enrichment, Kyoto encyclopedia of genes and genomes (KEGG) pathway enrichment and transcription factors. MiRTarBase database was used to predict target genes. Results A total of 19 differential miRNAs were screened out,of which 11 were up-regulated and 8 were down-regulated.Biological process of GO enrichment was enriched in signal transduction and cell communication; cellular component of GO enrichment was enriched in nucleus and cytoplasm; molecular function of GO enrichment was expressed in transcription factor activity, ubiquitin-specific protease activity and receptor signalling complex scaffold activity. KEGG pathway was shown mainly in glypican signalling pathway, TRAIL signalling pathway and S1P signalling pathway. The transcription factors related to miRNA mainly included: SP1, SP4, EGR1 and POU2F1. Forteen miRNAs have been experimentally verified to have target genes. Conclusions The differential miRNAs in moDCs of SLE patients may play an important role in the pathogenesis of SLE and provide new clue for the diagnosis of SLE.

Published
2021

39. The influencing factors of the cooperation behaviors of patients in department of pediatric dentistry

Author

GAO Hong, WANG Xue-qin, ZHU Jun-xia, and LI Jing

Subjects
Department of pediatric dentistry，, Dental anxiety ，, Behavior management，, Patient compliance，, Effect factors，, Medicine
Abstract

Children’s fear and anxiety and dental behavioral management problems are relatively usual in dental settings, and it is a barrier to dental care. Many factors associated with these problems will be reviewed from the aspects of doctor, patient and guardian, in order to reduce the incidence of dental fear and anxiety/dental behavioral management problem in dental departments.

Published
2016
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42. Progress in Photocatalytic Degradation of Organic Wastewater by Graphene Binary Composites

Author

Wang Xue-Qin and He Qin

Subjects
Environmental sciences, GE1-350
Abstract

Graphene composites not only have most advantages of graphene, but also have the characteristics of easy regulation, morphology and so on. Among many applications, graphene composite photocatalytic degradation of organic wastewater is one of the most likely graphene technologies. At present, the most studied graphene complexes include graphene monophyletic complex, graphene binary complex and graphene ternary complex. In this paper, the preparation of graphene binary complex and the research status of photocatalytic degradation of organic wastewater are summarized, and the existing problems are analyzed in order to provide a reference for the further research and application of graphene complex photocatalytic degradation of organic wastewater.

Published
2021
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