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● To achieve food security, Chinese agriculture– food system could not achieve C neutrality. ● China’s dual carbon goals has put forward more strict requirements for the green development of agriculture. ● The realization of C mitigation potential lies in the extensive application of existing technologies and technological innovation. The agricultural sector, a major source of greenhouse gas emissions, and emissions from agriculture must be reduced substantially to achieve carbon (C) neutrality. Based on a literature analysis and other research results, this study investigated the effects and prospects of C reduction in agricultural systems under different scenarios (i.e., methods and approaches) in the context of China’s dual C goals, as those working in the agricultural sector have yet to reach a consensus on how to move forward. Different views, standards, and countermeasures were analyzed to provide a reference for agricultural action supporting China’s C neutrality goal.

Here, we report a strategy enabling triple switchable chemo‐, regio‐, and stereodivergence in newly developed palladium‐catalyzed cycloadditions of allenes. An asymmetric pseudo‐stereodivergent cycloaddition of allenes bearing a primary leaving group at the α‐position, where a dynamic kinetic asymmetric hydroalkoxylation of racemic unactivated allenes was the enantio‐determining step, is realized, providing four stereoisomers [(Z,R), (Z,S), (E,S), and (E,R)] containing a di‐substituted alkene scaffold and a stereogenic center. By tuning reaction conditions, a mechanistically distinctive cycloaddition is uncovered selectively with the same set of substrates. By switching the position of the leaving group of allenes, a cycloaddition involving an intermolecular O‐attack is disclosed. Diverse mechanisms of the cycloaddition reactions of allenes enable rapid access to structurally and stereochemically diverse 3,4‐dihydro‐2H‐1,4‐benzoxazines in high efficiency and selectivity. [ABSTRACT FROM AUTHOR]

New soil organic carbon (SOC) formation in cropland from straw/stover or manure input is a vital source of SOC for climate change mitigation. However, location and variations in the efficiency, specifically the ratio of new SOC formation to organic C input (NCE), remain unquantified globally. In this study, the spatial variability of cropland NCE from straw/stover or manure input and explanatory factors were determined by analyzing 897 pairs of long‐term field measurements from 404 globally distributed sites and by mapping grid‐level cropland NCEs. The global NCE for paddy and upland averaged 13.8% (8.7%–25.1%, 5th–95th percentile) and 10.9% (6.8%–17.3%), respectively. The initial SOC and the clay content of soil, rather than temperature, were the most important factors regulating NCE. A parabola with an apex at approximately 17 g kg−1 between the initial SOC and NCE was resolved, and a positive correlation between soil clay content and NCE was observed. High‐resolution mapping of the global NCE derived from manure/straw and insight into NCE dynamics provide a benchmark for diagnosing cropland soil C dynamics under climate change and identifying priority regions and actions for C management. [ABSTRACT FROM AUTHOR]

Determining the dynamics of organic carbon in subsoil (SOC, depth of 20–100 cm) is important with respect to the global C cycle and warming mitigation. However, there is still a huge knowledge gap in the dynamics of spatiotemporal changes in SOC in this layer. Combining traditional depth functions and machine-learning methods, we achieved soil β values and SOC dynamics at high resolution for global ecosystems (cropland, grassland, and forestland). First, quantified the spatial variability characteristics of soil β values and driving factors by analyzing 1221 soil profiles (0–100 cm) of globally distributed field observations. Then, based on multiple environmental variables and soil profile data, we mapped the grid-level soil β values with machine-learning approaches. Lastly, we evaluated the SOC density spatial distribution in different soil layers to determine the subsoil SOC stocks of various ecosystems. The subsoil SOC density values of cropland, grassland, and forestland were 63.8, 83.3, and 100.4 Mg ha–1, respectively. SOC density decreased with increasing depth, ranging from 5.6 to 30.8 Mg ha–1 for cropland, 7.5 to 40.0 Mg ha–1 for grassland, and 9.6 to 47.0 Mg ha–1 for forestland. The global subsoil SOC stock was 912 Pg C (cropland, grassland, and forestland were 67, 200, and 644 Pg C), in which an average of 54 % resided in the top 0–100 cm of the soil profile. Our results provide information on the vertical distribution and spatial patterns of SOC density at a 10 km resolution for areas of Global ecosystems, which providing a scientific basis for future studies pertaining to Earth system models. The dataset is open-access and available at https://doi.org/10.5281/zenodo.10846543 (Wang et al., 2024). [ABSTRACT FROM AUTHOR]

ObjectiveTo identify and investigate the susceptibility genes of Kashin-Beck disease (KBD) in Chinese population.MethodsWhole-exome capturing and sequencing technology was used for the detection of genetic variations in 19 individuals from six families with high incidence of KBD. A total of 44 polymorphisms from 41 genes were genotyped from a total of 144 cases and 144 controls by using MassARRAY under the standard protocol from Sequenom. Association was applied on the data by using PLINK1.07.ResultsIn the sequencing stage, each sample showed approximately 70-fold coverage, thus covering more than 99% of the target regions. Among the single nucleotide polymorphisms (SNPs) used in the transmission disequilibrium test, 108 had a p-value of

A website with vaccine information and interactive social media was reported to improve maternal influenza vaccine uptake. This study aimed to evaluate cost-effectiveness of a web-based intervention on influenza vaccine uptake among pregnant women from the perspective of US healthcare providers. A one-year decision-analytic model estimated outcomes in a hypothetical cohort of pregnant women with: (1) website with vaccine information and interactive social media (intervention group), and (2) usual care (usual care group). Primary measures included influenza infection, influenza-related hospitalization, mortality, direct medical cost, and quality-adjusted life-year (QALY) loss. In base-case analysis, intervention group reduced cost (by USD28), infection (by 28 per 1,000 pregnant women), hospitalization (by 1.226 per 1,000 pregnant women), mortality (by 0.0036 per 1,000 pregnant women), and saved 0.000305 QALYs versus usual care group. Relative improvement of vaccine uptake by the intervention and number of pregnant women in the healthcare system were two influential factors identified in deterministic sensitivity analysis. The intervention was cost-effective in 99.5% of 10,000 Monte Carlo simulations (at willingness-to-pay threshold 50,000 USD/QALY). A website with vaccine information and interactive social media to promote influenza vaccination for pregnant women appears to reduce direct medical costs and gain QALYs from the perspective of US healthcare providers. [ABSTRACT FROM AUTHOR]