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114 results on '"Wang, Yitang"'

4. Outlier Detection and Correction for Time Series Data of Tunnel Boring Machine

Author

Wang, Yitang, Wang, Suhang, Pang, Yong, Song, Xueguan, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Yang, Huayong, editor, Liu, Honghai, editor, Zou, Jun, editor, Yin, Zhouping, editor, Liu, Lianqing, editor, Yang, Geng, editor, Ouyang, Xiaoping, editor, and Wang, Zhiyong, editor

Published
2023
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5. Tunneling Operational Data Imputation with Radial Basis Function Neural Network

Author

Wang, Yitang, Pang, Yong, Song, Xueguan, Sun, Wei, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Tan, Kay Chen, Series Editor, Hu, Cungang, editor, and Cao, Wenping, editor

Published
2023
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6. Recognition of Tunneling Boring Machine Operating Status Based on the Time Series Analysis

Author

Pang, Yong, Wang, Yitang, Zhang, Shuai, Wang, Suhang, Song, Xueguan, Sun, Wei, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Tan, Kay Chen, Series Editor, Hu, Cungang, editor, and Cao, Wenping, editor

Published
2023
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14. A Denoising Method by Low-Rank and Sparse Representations and Its Application in Tunnel Boring Machine

Author

Wang, Yitang, Fu, Tau, Zhang, Tianci, Song, Xueguan, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Cao, Wenping, editor, Hu, Cungang, editor, Huang, Xiaoyan, editor, Chen, Xiangping, editor, and Tao, Jun, editor

Published
2022
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15. Ethiodized poppyseed oil-based contrast medium is superior to water-based contrast medium during hysterosalpingography regarding image quality improvement and fertility enhancement: A multicentric, randomized and controlled trial

Author

Zhang, Jing, Lan, Weishun, Wang, Yitang, Chen, Kunshan, Zhang, Guofu, Yang, Wenzhong, Chen, Huichun, Xu, Wenjian, Ma, Jianxin, Qin, Wenhua, Zhang, Yao, Wang, Wuquan, Wang, Huichun, Dong, Zijun, Wang, Yanli, Chen, Yi, Gang, Ning, and Tang, Yichuan

Published
2022
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19. Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux

Author

Buschmann, Mary M, Shen, Le, Rajapakse, Harsha, Raleigh, David R, Wang, Yitang, Wang, Yingmin, Lingaraju, Amulya, Zha, Juanmin, Abbott, Elliot, McAuley, Erin M, Breskin, Lydia A, Wu, Licheng, Anderson, Kenneth, Turner, Jerrold R, and Weber, Christopher R

Subjects
Biochemistry and Cell Biology, Biological Sciences, Digestive Diseases, Aetiology, 2.1 Biological and endogenous factors, Caco-2 Cells, Endocytosis, Gene Knockdown Techniques, Humans, Intestinal Mucosa, Occludin, Permeability, Protein Binding, Protein Structure, Tertiary, Sequence Deletion, Signal Transduction, Tight Junctions, Tumor Necrosis Factor-alpha, Medical and Health Sciences, Developmental Biology, Biochemistry and cell biology
Abstract

In vitro and in vivo studies implicate occludin in the regulation of paracellular macromolecular flux at steady state and in response to tumor necrosis factor (TNF). To define the roles of occludin in these processes, we established intestinal epithelia with stable occludin knockdown. Knockdown monolayers had markedly enhanced tight junction permeability to large molecules that could be modeled by size-selective channels with radii of ~62.5 Å. TNF increased paracellular flux of large molecules in occludin-sufficient, but not occludin-deficient, monolayers. Complementation using full-length or C-terminal coiled-coil occludin/ELL domain (OCEL)-deficient enhanced green fluorescent protein (EGFP)-occludin showed that TNF-induced occludin endocytosis and barrier regulation both required the OCEL domain. Either TNF treatment or OCEL deletion accelerated EGFP-occludin fluorescence recovery after photobleaching, but TNF treatment did not affect behavior of EGFP-occludin(ΔOCEL). Further, the free OCEL domain prevented TNF-induced acceleration of occludin fluorescence recovery, occludin endocytosis, and barrier loss. OCEL mutated within a recently proposed ZO-1-binding domain (K433) could not inhibit TNF effects, but OCEL mutated within the ZO-1 SH3-GuK-binding region (K485/K488) remained functional. We conclude that OCEL-mediated occludin interactions are essential for limiting paracellular macromolecular flux. Moreover, our data implicate interactions mediated by the OCEL K433 region as an effector of TNF-induced barrier regulation.

Published
2013

20. An Expensive Many-Objective Optimization Algorithm Based on Efficient Expected Hypervolume Improvement

Author

Pang, Yong, Wang, Yitang, Zhang, Shuai, Lai, Xiaonan, Sun, Wei, and Song, Xueguan

Abstract

The expected hypervolume improvement (EHVI) is one of the most popular infill criteria for multiobjective optimization problems. Although it has a significant advantage in exploring potential Pareto-optimal solutions, it has rarely been applied in many-objective problems due to its high computational cost. To address this issue, this article proposes an expensive many-objective optimization algorithm based on the framework of nondominated sorting genetic algorithm III (NSGA-III) and assisted by the kriging surrogate models. In the proposed algorithm, the Monte Carlo sampling (MCS) method for EHVI estimation is improved by importance sampling, in which only one sampling process is required during the entire optimization process using a uniform distribution in normalized objective space. Considering the predicted uncertainty from the kriging model, an uncertainty-assisted nondominated sorting approach is proposed to substitute for the conventional approach in NSGA-III. In the proposed method, the predicted uncertainty is incorporated into the objective space as one independent dimension for nondominated sorting, which can enable the exploration of potential points with desirable EHVI values. In addition, the proposed algorithm considers the diversity of the solutions by de-emphasizing the pursuit of the best EHVI. The experimental results on benchmark problems demonstrate that the proposed EHVI calculation method can save computational costs compared with MCS and indicate the superiority of the proposed algorithm over the others.

Published
2023
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21. Data-Driven Approach for Passenger Mobility Pattern Recognition Using Spatiotemporal Embedding

Author

Yu, Chao, Li, Haiying, Xu, Xinyue, Liu, Jun, Miao, Jianrui, Wang, Yitang, and Sun, Qi

Subjects
Natural language interfaces, Computational linguistics, Language processing, Transportation industry
Abstract

Urban mobility pattern recognition has great potential in revealing human travel mechanism, discovering passenger travel purpose, and predicting and managing traffic demand. This paper aims to propose a data-driven method to identify metro passenger mobility patterns based on Automatic Fare Collection (AFC) data and geo-based data. First, Point of Information (POI) data within 500 meters of the metro stations are captured to characterize the spatial attributes of the stations. Especially, a fusion method of multisource geo-based data is proposed to convert raw POI data into weighted POI data considering service capabilities. Second, an unsupervised learning framework based on stacked auto-encoder (SAE) is designed to embed the spatiotemporal information of trips into low-dimensional dense trip vectors. In detail, the embedded spatiotemporal information includes spatial features (POI categories around the origin station and that around the destination station) and temporal features (start time, day of the week, and travel time). Third, a density-based clustering algorithm is introduced to identify passenger mobility patterns based on the embedded dense trip vectors. Finally, a case of Beijing metro network is used to verify the feasibility of the above methodology. The results show that the proposed method performs well in recognizing mobility patterns and outperforms the existing methods., Author(s): Chao Yu [1,2]; Haiying Li [1]; Xinyue Xu (corresponding author) [1]; Jun Liu [1]; Jianrui Miao [1]; Yitang Wang [3]; Qi Sun [4] 1. Introduction The number of urban [...]

Published
2021
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22. Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host

Author

Meisel, Marlies, Hinterleitner, Reinhard, Pacis, Alain, Chen, Li, Earley, Zachary M., Mayassi, Toufic, Pierre, Joseph F., Ernest, Jordan D., Galipeau, Heather J., Thuille, Nikolaus, Bouziat, Romain, Buscarlet, Manuel, Ringus, Daina L., Wang, Yitang, Li, Ye, Dinh, Vu, Kim, Sangman M., McDonald, Benjamin D., Zurenski, Matthew A., Musch, Mark W., Furtado, Glaucia C., Lira, Sergio A., Baier, Gottfried, Chang, Eugene B., Eren, A. Murat, Weber, Christopher R., Busque, Lambert, Godley, Lucy A., Verdú, Elena F., Barreiro, Luis B., and Jabri, Bana

Published
2018
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31. Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase-3 Expression

Author

Kuo, Wei-Ting, primary, Shen, Le, additional, Zuo, Li, additional, Shashikanth, Nitesh, additional, Ong, Ma.Lora Drizella M., additional, Wu, Licheng, additional, Zha, Juanmin, additional, Edelblum, Karen L., additional, Wang, Yitang, additional, Wang, Yingmin, additional, Nilsen, Steven P., additional, and Turner, Jerrold R., additional

Published
2019
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32. Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis

Author

Graham, W. Vallen, primary, He, Weiqi, additional, Marchiando, Amanda M., additional, Zha, Juanmin, additional, Singh, Gurminder, additional, Li, Hua-Shan, additional, Biswas, Amlan, additional, Ong, Ma. Lora Drizella M., additional, Jiang, Zhi-Hui, additional, Choi, Wangsun, additional, Zuccola, Harmon, additional, Wang, Yitang, additional, Griffith, James, additional, Wu, Jingshing, additional, Rosenberg, Harry J., additional, Wang, Yingmin, additional, Snapper, Scott B., additional, Ostrov, David, additional, Meredith, Stephen C., additional, Miller, Lawrence W., additional, and Turner, Jerrold R., additional

Published
2019
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33. A calcium transport mechanism for atrial fibrillation in Tbx5-mutant mice

Author

Dai, Wenli, primary, Laforest, Brigitte, additional, Tyan, Leonid, additional, Shen, Kaitlyn M, additional, Nadadur, Rangarajan D, additional, Alvarado, Francisco J, additional, Mazurek, Stefan R, additional, Lazarevic, Sonja, additional, Gadek, Margaret, additional, Wang, Yitang, additional, Li, Ye, additional, Valdivia, Hector H, additional, Shen, Le, additional, Broman, Michael T, additional, Moskowitz, Ivan P, additional, and Weber, Christopher R, additional

Published
2019
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34. Author response: A calcium transport mechanism for atrial fibrillation in Tbx5-mutant mice

Author

Dai, Wenli, primary, Laforest, Brigitte, additional, Tyan, Leonid, additional, Shen, Kaitlyn M, additional, Nadadur, Rangarajan D, additional, Alvarado, Francisco J, additional, Mazurek, Stefan R, additional, Lazarevic, Sonja, additional, Gadek, Margaret, additional, Wang, Yitang, additional, Li, Ye, additional, Valdivia, Hector H, additional, Shen, Le, additional, Broman, Michael T, additional, Moskowitz, Ivan P, additional, and Weber, Christopher R, additional

Published
2019
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37. ZO-1 interactions with F-actin and occludin direct epithelial polarization and single lumen specification in 3D culture

Author

Warren, Michael H., Buschmann, Mary M., Buckley, Aaron, Turner, Jerrold R., Joseph, Nora E., Hildebrand, Jeffrey, Margolis, Ben, Choi, Wangsun, Pavlyuk, Roman, Fanning, Alan S., Odenwald, Matthew A., Wang, Yitang, and Shashikanth, Nitesh

Abstract

Epithelia within tubular organs form and expand lumens. Failure of these processes can result in serious developmental anomalies. Although tight junction assembly is crucial to epithelial polarization, the contribution of specific tight junction proteins to lumenogenesis is undefined. Here, we show that ZO-1 (also known as TJP1) is necessary for the formation of single lumens. Epithelia lacking this tight junction scaffolding protein form cysts with multiple lumens and are defective in the earliest phases of polarization, both in two and three dimensions. Expression of ZO-1 domain-deletion mutants demonstrated that the actin-binding region and U5-GuK domain are crucial to single lumen development. For actin-binding region, but not U5-GuK domain, mutants, this could be overcome by strong polarization cues from the extracellular matrix. Analysis of the U5-GuK binding partners shroom2, α-catenin and occludin showed that only occludin deletion led to multi-lumen cysts. Like ZO-1-deficiency, occludin deletion led to mitotic spindle orientation defects. Single lumen formation required the occludin OCEL domain, which binds to ZO-1. We conclude that ZO-1–occludin interactions regulate multiple phases of epithelial polarization by providing cell-intrinsic signals that are required for single lumen formation.

Published
2017
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41. Mechanisms of AP Prolongation and Triggered Activity in a TBX5 Model of Atrial Fibrillation

Author

Tyan, Leonid, primary, Dai, Wenli, additional, Nadadur, Rajiv, additional, Wang, Yitang, additional, Mazurek, Stefan, additional, Bekeny, Jenna, additional, Shen, Kaitlyn, additional, Gadek, Margaret, additional, Laforest, Brigitte, additional, Alvarado, Francisco, additional, Valdivia, Hector, additional, Broman, Michael, additional, Shen, Le, additional, Moskowitz, Ivan, additional, and Weber, Christopher, additional

Published
2018
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44. ZO-1 interactions with F-actin and occludin direct epithelial polarization and single lumen specification in 3D culture

Author

Odenwald, Matthew A., primary, Choi, Wangsun, additional, Buckley, Aaron, additional, Shashikanth, Nitesh, additional, Joseph, Nora E., additional, Wang, Yitang, additional, Warren, Michael H., additional, Buschmann, Mary M., additional, Pavlyuk, Roman, additional, Hildebrand, Jeffrey, additional, Margolis, Ben, additional, Fanning, Alan S., additional, and Turner, Jerrold R., additional

Published
2016
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