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Objective: Ensuring the precision in motion tracking for MRI-guided Radiotherapy (MRIgRT) is crucial for the delivery of effective treatments. This study refined the motion tracking accuracy in MRIgRT through the innovation of an automatic real-time tracking method, leveraging an enhanced Tracking-Learning-Detection (ETLD) framework coupled with automatic segmentation. Methods: We developed a novel MRIgRT motion tracking method by integrating two primary methods: the ETLD framework and an improved Chan-Vese model (ICV), named ETLD+ICV. The TLD framework was upgraded to suit real-time cine MRI, including advanced image preprocessing, no-reference image quality assessment, an enhanced median-flow tracker, and a refined detector with dynamic search region adjustments. Additionally, ICV was combined for precise coverage of the target volume, which refined the segmented region frame by frame using tracking results, with key parameters optimized. Tested on 3.5D MRI scans from 10 patients with liver metastases, our method ensures precise tracking and accurate segmentation vital for MRIgRT. Results: An evaluation of 106,000 frames across 77 treatment fractions revealed sub-millimeter tracking errors of less than 0.8mm, with over 99% precision and 98% recall for all subjects, underscoring the robustness and efficacy of the ETLD. Moreover, the ETLD+ICV yielded a dice global score of more than 82% for all subjects, demonstrating the proposed method's extensibility and precise target volume coverage. Conclusions: This study successfully developed an automatic real-time motion tracking method for MRIgRT that markedly surpasses current methods. The novel method not only delivers exceptional precision in tracking and segmentation but also demonstrates enhanced adaptability to clinical demands, positioning it as an indispensable asset in the quest to augment the efficacy of radiotherapy treatments.

In this work, we propose an Implicit Regularization Enhancement (IRE) framework to accelerate the discovery of flat solutions in deep learning, thereby improving generalization and convergence. Specifically, IRE decouples the dynamics of flat and sharp directions, which boosts the sharpness reduction along flat directions while maintaining the training stability in sharp directions. We show that IRE can be practically incorporated with {\em generic base optimizers} without introducing significant computational overload. Experiments show that IRE consistently improves the generalization performance for image classification tasks across a variety of benchmark datasets (CIFAR-10/100, ImageNet) and models (ResNets and ViTs). Surprisingly, IRE also achieves a $2\times$ {\em speed-up} compared to AdamW in the pre-training of Llama models (of sizes ranging from 60M to 229M) on datasets including Wikitext-103, Minipile, and Openwebtext. Moreover, we provide theoretical guarantees, showing that IRE can substantially accelerate the convergence towards flat minima in Sharpness-aware Minimization (SAM)., Comment: 44 pages, accepted by NeurIPS 2024

Systems of spins with strong dipolar interactions and controlled dimensionality enable new explorations in quantum sensing and simulation. In this work, we investigate the creation of strong dipolar interactions in a two-dimensional ensemble of nitrogen-vacancy (NV) centers generated via plasma-enhanced chemical vapor deposition (PECVD) on (111)-oriented diamond substrates. We find that diamond growth on the (111) plane yields high incorporation of spins, both nitrogen and NV centers, where the density of the latter is tunable via the miscut of the diamond substrate. Our process allows us to form dense, preferentially aligned, 2D NV ensembles with volume-normalized AC sensitivity down to $\eta_{AC}$ = 810 pT um$^{3/2}$ Hz$^{-1/2}$. Furthermore, we show that (111) affords maximally positive dipolar interactions amongst a 2D NV ensemble, which is crucial for leveraging dipolar-driven entanglement schemes and exploring new interacting spin physics.

This paper presents an Exploratory 3D Dance generation framework, E3D2, designed to address the exploration capability deficiency in existing music-conditioned 3D dance generation models. Current models often generate monotonous and simplistic dance sequences that misalign with human preferences because they lack exploration capabilities. The E3D2 framework involves a reward model trained from automatically-ranked dance demonstrations, which then guides the reinforcement learning process. This approach encourages the agent to explore and generate high quality and diverse dance movement sequences. The soundness of the reward model is both theoretically and experimentally validated. Empirical experiments demonstrate the effectiveness of E3D2 on the AIST++ dataset. Project Page: https://sites.google.com/view/e3d2., Comment: AAAI-24

Inverse reinforcement learning (IRL) aims to explicitly infer an underlying reward function based on collected expert demonstrations. Considering that obtaining expert demonstrations can be costly, the focus of current IRL techniques is on learning a better-than-demonstrator policy using a reward function derived from sub-optimal demonstrations. However, existing IRL algorithms primarily tackle the challenge of trajectory ranking ambiguity when learning the reward function. They overlook the crucial role of considering the degree of difference between trajectories in terms of their returns, which is essential for further removing reward ambiguity. Additionally, it is important to note that the reward of a single transition is heavily influenced by the context information within the trajectory. To address these issues, we introduce the Distance-rank Aware Sequential Reward Learning (DRASRL) framework. Unlike existing approaches, DRASRL takes into account both the ranking of trajectories and the degrees of dissimilarity between them to collaboratively eliminate reward ambiguity when learning a sequence of contextually informed reward signals. Specifically, we leverage the distance between policies, from which the trajectories are generated, as a measure to quantify the degree of differences between traces. This distance-aware information is then used to infer embeddings in the representation space for reward learning, employing the contrastive learning technique. Meanwhile, we integrate the pairwise ranking loss function to incorporate ranking information into the latent features. Moreover, we resort to the Transformer architecture to capture the contextual dependencies within the trajectories in the latent space, leading to more accurate reward estimation. Through extensive experimentation, our DRASRL framework demonstrates significant performance improvements over previous SOTA methods.

The automatic co-speech gesture generation draws much attention in computer animation. Previous works designed network structures on individual datasets, which resulted in a lack of data volume and generalizability across different motion capture standards. In addition, it is a challenging task due to the weak correlation between speech and gestures. To address these problems, we present UnifiedGesture, a novel diffusion model-based speech-driven gesture synthesis approach, trained on multiple gesture datasets with different skeletons. Specifically, we first present a retargeting network to learn latent homeomorphic graphs for different motion capture standards, unifying the representations of various gestures while extending the dataset. We then capture the correlation between speech and gestures based on a diffusion model architecture using cross-local attention and self-attention to generate better speech-matched and realistic gestures. To further align speech and gesture and increase diversity, we incorporate reinforcement learning on the discrete gesture units with a learned reward function. Extensive experiments show that UnifiedGesture outperforms recent approaches on speech-driven gesture generation in terms of CCA, FGD, and human-likeness. All code, pre-trained models, databases, and demos are available to the public at https://github.com/YoungSeng/UnifiedGesture., Comment: 16 pages, 11 figures, ACM MM 2023

The previous SpEx+ has yielded outstanding performance in speaker extraction and attracted much attention. However, it still encounters inadequate utilization of multi-scale information and speaker embedding. To this end, this paper proposes a new effective speaker extraction system with multi-scale interfusion and conditional speaker modulation (ConSM), which is called MC-SpEx. First of all, we design the weight-share multi-scale fusers (ScaleFusers) for efficiently leveraging multi-scale information as well as ensuring consistency of the model's feature space. Then, to consider different scale information while generating masks, the multi-scale interactive mask generator (ScaleInterMG) is presented. Moreover, we introduce ConSM module to fully exploit speaker embedding in the speech extractor. Experimental results on the Libri2Mix dataset demonstrate the effectiveness of our improvements and the state-of-the-art performance of our proposed MC-SpEx., Comment: Accepted by InterSpeech 2023

Recent advances in visual reinforcement learning (RL) have led to impressive success in handling complex tasks. However, these methods have demonstrated limited generalization capability to visual disturbances, which poses a significant challenge for their real-world application and adaptability. Though normalization techniques have demonstrated huge success in supervised and unsupervised learning, their applications in visual RL are still scarce. In this paper, we explore the potential benefits of integrating normalization into visual RL methods with respect to generalization performance. We find that, perhaps surprisingly, incorporating suitable normalization techniques is sufficient to enhance the generalization capabilities, without any additional special design. We utilize the combination of two normalization techniques, CrossNorm and SelfNorm, for generalizable visual RL. Extensive experiments are conducted on DMControl Generalization Benchmark and CARLA to validate the effectiveness of our method. We show that our method significantly improves generalization capability while only marginally affecting sample efficiency. In particular, when integrated with DrQ-v2, our method enhances the test performance of DrQ-v2 on CARLA across various scenarios, from 14% of the training performance to 97%.

Data augmentation (DA) is a crucial technique for enhancing the sample efficiency of visual reinforcement learning (RL) algorithms. Notably, employing simple observation transformations alone can yield outstanding performance without extra auxiliary representation tasks or pre-trained encoders. However, it remains unclear which attributes of DA account for its effectiveness in achieving sample-efficient visual RL. To investigate this issue and further explore the potential of DA, this work conducts comprehensive experiments to assess the impact of DA's attributes on its efficacy and provides the following insights and improvements: (1) For individual DA operations, we reveal that both ample spatial diversity and slight hardness are indispensable. Building on this finding, we introduce Random PadResize (Rand PR), a new DA operation that offers abundant spatial diversity with minimal hardness. (2) For multi-type DA fusion schemes, the increased DA hardness and unstable data distribution result in the current fusion schemes being unable to achieve higher sample efficiency than their corresponding individual operations. Taking the non-stationary nature of RL into account, we propose a RL-tailored multi-type DA fusion scheme called Cycling Augmentation (CycAug), which performs periodic cycles of different DA operations to increase type diversity while maintaining data distribution consistency. Extensive evaluations on the DeepMind Control suite and CARLA driving simulator demonstrate that our methods achieve superior sample efficiency compared with the prior state-of-the-art methods., Comment: NeurIPS 2023 poster

Traditional blockchain design gives miners or validators full control over transaction ordering, i.e., they can freely choose which transactions to include or exclude, as well as in which order. While not an issue initially, the emergence of decentralized finance has introduced new transaction order dependencies allowing parties in control of the ordering to make a profit by front-running others' transactions. In this work, we present the Decentralized Clock Network, a new approach for achieving fair transaction ordering. Users submit their transactions to the network's clocks, which run an agreement protocol that provides each transaction with a timestamp of receipt which is then used to define the transactions' order. By separating agreement from ordering, our protocol is efficient and has a simpler design compared to other available solutions. Moreover, our protocol brings to the blockchain world the paradigm of asynchronous fallback, where the algorithm operates with stronger fairness guarantees during periods of synchronous use, switching to an asynchronous mode only during times of increased network delay., Comment: In Proceedings of 27th International Conference on Principles of Distributed Systems (OPODIS)

Subband-based approaches process subbands in parallel through the model with shared parameters to learn the commonality of local spectrums for noise reduction. In this way, they have achieved remarkable results with fewer parameters. However, in some complex environments, the lack of global spectral information has a negative impact on the performance of these subband-based approaches. To this end, this paper introduces the subband interaction as a new way to complement the subband model with the global spectral information such as cross-band dependencies and global spectral patterns, and proposes a new lightweight single-channel speech enhancement framework called Interactive Subband Network (Inter-SubNet). Experimental results on DNS Challenge - Interspeech 2021 dataset show that the proposed Inter-SubNet yields a significant improvement over the subband model and outperforms other state-of-the-art speech enhancement approaches, which demonstrate the effectiveness of subband interaction., Comment: Accepted by ICASSP 2023

Spin squeezing is a form of entanglement that reshapes the quantum projection noise to improve measurement precision. Here, we provide numerical and analytic evidence for the following conjecture: any Hamiltonian exhibiting finite temperature, easy-plane ferromagnetism can be used to generate scalable spin squeezing, thereby enabling quantum-enhanced sensing. Our conjecture is guided by a connection between the quantum Fisher information of pure states and the spontaneous breaking of a continuous symmetry. We demonstrate that spin-squeezing exhibits a phase diagram with a sharp transition between scalable squeezing and non-squeezing. This transition coincides with the equilibrium phase boundary for XY order at a finite temperature. In the scalable squeezing phase, we predict a sensitivity scaling that lies in between the standard quantum limit and the scaling achieved in all-to-all coupled one-axis twisting models. A corollary of our conjecture is that short-ranged versions of two-axis twisting cannot yield scalable metrological gain. Our results provide insights into the landscape of Hamiltonians that can be used to generate metrologically useful quantum states., Comment: 6 pages, 3 figures + 24 pages, 13 figures

FullSubNet has shown its promising performance on speech enhancement by utilizing both fullband and subband information. However, the relationship between fullband and subband in FullSubNet is achieved by simply concatenating the output of fullband model and subband units. It only supplements the subband units with a small quantity of global information and has not considered the interaction between fullband and subband. This paper proposes a fullband-subband cross-attention (FSCA) module to interactively fuse the global and local information and applies it to FullSubNet. This new framework is called as FS-CANet. Moreover, different from FullSubNet, the proposed FS-CANet optimize the fullband extractor by temporal convolutional network (TCN) blocks to further reduce the model size. Experimental results on DNS Challenge - Interspeech 2021 dataset show that the proposed FS-CANet outperforms other state-of-the-art speech enhancement approaches, and demonstrate the effectiveness of fullband-subband cross-attention., Comment: Accepted by InterSpeech 2022. arXiv admin note: text overlap with arXiv:2203.12188

Systems of spins engineered with tunable density and reduced dimensionality enable a number of advancements in quantum sensing and simulation. Defects in diamond, such as nitrogen-vacancy (NV) centers and substitutional nitrogen (P1 centers), are particularly promising solid-state platforms to explore. However, the ability to controllably create coherent, two-dimensional spin systems and characterize their properties, such as density, depth confinement, and coherence is an outstanding materials challenge. We present a refined approach to engineer dense ($\gtrsim$1 ppm$\cdot$nm), 2D nitrogen and NV layers in diamond using delta-doping during plasma-enhanced chemical vapor deposition (PECVD) epitaxial growth. We employ both traditional materials techniques, e.g. secondary ion mass spectrometry (SIMS), alongside NV spin decoherence-based measurements to characterize the density and dimensionality of the P1 and NV layers. We find P1 densities of 5-10 ppm$\cdot$nm, NV densities between 1 and 3.5 ppm$\cdot$nm tuned via electron irradiation dosage, and depth confinement of the spin layer down to 1.6 nm. We also observe high (up to 0.74) ratios of P1 to NV centers and reproducibly long NV coherence times, dominated by dipolar interactions with the engineered P1 and NV spin baths.

Previously proposed FullSubNet has achieved outstanding performance in Deep Noise Suppression (DNS) Challenge and attracted much attention. However, it still encounters issues such as input-output mismatch and coarse processing for frequency bands. In this paper, we propose an extended single-channel real-time speech enhancement framework called FullSubNet+ with following significant improvements. First, we design a lightweight multi-scale time sensitive channel attention (MulCA) module which adopts multi-scale convolution and channel attention mechanism to help the network focus on more discriminative frequency bands for noise reduction. Then, to make full use of the phase information in noisy speech, our model takes all the magnitude, real and imaginary spectrograms as inputs. Moreover, by replacing the long short-term memory (LSTM) layers in original full-band model with stacked temporal convolutional network (TCN) blocks, we design a more efficient full-band module called full-band extractor. The experimental results in DNS Challenge dataset show the superior performance of our FullSubNet+, which reaches the state-of-the-art (SOTA) performance and outperforms other existing speech enhancement approaches., Comment: Accepted by ICASSP 2022