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Your search keyword '"Warburton, Katharine L."' showing total 11 results
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11 results on '"Warburton, Katharine L."'

7. UK rates of occupational skin disease attributed to rubber accelerators, 1996-2012

Author

Warburton, Katharine L, Urwin, Rachel, Carder, Melanie, Turner, Susan, Agius, Raymond, and Wilkinson, S Mark

Subjects
body regions, latex, technology, industry, and agriculture, rubber, epidemiology, contact urticaria, occupational, allergic contact dermatitis, rubber accelerators
Abstract

BACKGROUND: Natural and synthetic rubbers containing rubber accelerators are well-known causes of allergic contact dermatitis (ACD). Latex contact urticaria (CU) has been widely reported, especially when powdered latex glove use was commonplace. Consequently, interventions to reduce latex exposure by altering glove manufacture were introduced. OBJECTIVE: This study aimed to analyse trends in UK-reported incidence of occupational skin disease associated with rubber accelerators. METHOD: We analysed cases reported to EPIDERM (part of The Health and Occupation Research network) of occupational ACD caused by natural and synthetic rubber products, between 1996 and 2012. RESULTS: For the studied period, a decreasing incidence of ACD associated with rubber products was found, with an average annual change of -1.2% [95% confidence interval (CI) -3.1 to 0.7]. The number of cases of latex CU (n = 580) significantly declined. The number of cases of ACD caused by mercapto mix and mercaptobenzothiazole (n = 177) and thiuram mix (n = 603) also declined. Reports of ACD associated with carba mix and its constituents (n = 219) increased significantly, by an average annual percentage of 10.1% (95%CI: 6.1-14.2). Twenty-six cases of ACD caused by rarer rubber compounds were identified, highlighting skin disease attributable to less widely recognized chemicals. CONCLUSIONS: These data show a falling reported incidence of occupational ACD attributed to rubber chemicals, but within this a significant rise attributable to the constituents of the carba mix. Clinicians should recognize the changing diversity of chemicals used in rubber manufacturing, and consider including carba mix in their baseline series and testing beyond this in suspect cases to avoid false-negative results.

Published
2015
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9. Dermatological clues to neurological diagnoses.

Author

Warburton, Katharine L. and Wakerley, Benjamin

Subjects
*DIAGNOSIS of neurological disorders, *AIDS, *CEREBROVASCULAR disease, *DRUGS, *ENCEPHALITIS, *HEMANGIOMAS, *HIV infections, *MELANOMA, *MENINGITIS, *PERIPHERAL neuropathy, *NEUROLOGICAL disorders, *NEUROFIBROMATOSIS, *SKIN, *TUBEROUS sclerosis, *VON Hippel-Lindau disease, *SYMPTOMS
Abstract

The article focuses on the diagnosis of various dermatological disorders in neurology. It provides practical options for management of neurological disorders including stroke, peripheral neuropathy, and meningitis, which were accompanied by changes in dermatological signs that occurs before the onset of the symptoms. It examines common neurocutaneous disorders and skin lesions at different stages of HIV/AIDS, which include folliculitis, candidiasis, and herpes zoster.

Published
2011
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10. An unusual cause of bilateral ophthalmoplegia.

Author

Warburton, Katharine L., Austen, Elizabeth, Gough, Andrew, and Wihl, Gunther E.

Abstract

The authors present a case of a histologically confirmed giant cell arteritis that presented unusually with bilateral and multiple cranial nerve palsies and resolved following treatment with pulsed cyclophosphamide. The aetiology of the presenting features and the treatment choices are discussed. [ABSTRACT FROM AUTHOR]

Published
2010

11. Patch testing with rubber series in Europe: a critical review and recommendation.

Author

Warburton KL, Uter W, Geier J, Spiewak R, Mahler V, Crépy MN, Schuttelaar ML, Bauer A, and Wilkinson M

Subjects
Dermatitis, Allergic Contact epidemiology, Dermatitis, Allergic Contact etiology, Dermatitis, Occupational epidemiology, Dermatitis, Occupational etiology, Female, Humans, Latex Hypersensitivity epidemiology, Latex Hypersensitivity etiology, Male, Occupations, Prevalence, Dermatitis, Allergic Contact diagnosis, Dermatitis, Occupational diagnosis, Latex Hypersensitivity diagnosis, Patch Tests methods, Rubber adverse effects
Abstract

Background: Rubber additives constitute an important group of contact allergens, particularly in certain occupations., Objectives: To collect information regarding the current practice of using a 'rubber series' in Europe, and discuss this against the background of evidence concerning the prevalence of allergy in order to derive a recommendation for a 'European rubber series'., Methods: The following were performed: (i) a survey targeting all members of the COST action 'StanDerm' consortium, (ii) analysis of rubber contact allergy data in the database of the European Surveillance System on Contact Allergies, and (iii) a literature review., Results: Information from 13 countries was available, from one or several departments of dermatology, and occasionally occupational health. Apart from some substances tested only in single departments, a broad overlap regarding important allergens was evident, but considerable variation existed between departments., Conclusions: An up-to-date 'European rubber series' is recommended, with the exclusion of substances only of historical concern. A 'supplementary rubber series' containing allergens of less proven importance, requiring further analysis, is recommended for departments specializing in occupational contact allergy. These should be continually updated as new evidence emerges., (© 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

Published
2017
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