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39 results on '"Watanabe, Chiyuki"'

1. AJM300 (carotegrast methyl), an oral antagonist of α4-integrin, as induction therapy for patients with moderately active ulcerative colitis: a multicentre, randomised, double-blind, placebo-controlled, phase 3 study

Author

Motoya, Satoshi, Maemoto, Atsuo, Fujiya, Mikihiro, Ashida, Toshifumi, Goto, Mitsuru, Matsumoto, Takayuki, Suzuki, Yasuo, Hamahata, Yukihiro, Nakagawa, Tomoo, Kato, Naoya, Kato, Jun, Endo, Yutaka, Suzuki, Ryoichi, Matsuda, Koichiro, Ohmiya, Naoki, Katsushima, Shinji, Hosomi, Shuhei, Tarumi, Ken-ichi, Watanabe, Chiyuki, Saito, Mitsuru, Yokoyama, Yuichiro, Inaba, Tomoki, Sakata, Yasuhisa, Hongo, Hitoshi, Shibuya, Tomoyoshi, Kawakami, Kazuhiko, Kakuta, Yoichi, Irisawa, Atsushi, Yoshimura, Naoki, Fukuda, Katsuyuki, Shirai, Takayuki, Ichikawa, Hitoshi, Nagata, Junko, Suzuki, Takayoshi, Yokoyama, Kaoru, Tomidokoro, Takashi, Kojima, Yuichiro, Yamada, Masahiro, Yamamoto, Hideko, Yamamoto, Takayuki, Horiki, Noriyuki, Obata, Hirozumi, Inoue, Satoko, Tanaka, Shinji, Toyokawa, Tatsuya, Kunihiro, Masaki, Hisabe, Takashi, Ogata, Shinichi, Takeshima, Fuminao, Matsushima, Kayoko, Matsuhashi, Nobuyuki, Sakuraba, Hirotake, Iwabuchi, Masahiro, Tsuchiya, Akihiko, Uchiyama, Kan, Kanai, Takanori, Nakamura, Masanao, Yokoyama, Tadashi, Hida, Nobuyuki, Mitsuyama, Keiichi, Osada, Taro, Hiraoka, Sakiko, Tsuzuki, Tomoyuki, Masuo, Takashige, Hokari, Ryota, Kobayashi, Taku, Saruta, Masayuki, Araki, Masao, Araki, Hiroshi, Shimizu, Masahito, Kikuchi, Masakazu, Nishikawa, Takahiro, Takedatsu, Hidetoshi, Aoyagi, Kunihiko, Ochiai, Toshiaki, Toda, Nobuo, Mizokami, Yuji, Nagahori, Masakazu, Matsueda, Kazuhiro, Kino, Hitoshi, Kanamori, Akira, Suzuki, Tsunehiro, Sakurai, Toshiharu, Kudo, Masatoshi, Kitano, Atsuo, Hisamatsu, Tadakazu, Kumagai, Shinji, Ninomiya, Tomoyuki, Mori, Kenichiro, Yoshida, Shun-ichi, Goto, Mitsuhide, Matsuoka, Katsuyoshi, Watanabe, Mamoru, Ohmori, Toshihide, Nakajima, Koichi, Ishida, Tetsuya, Ishiguro, Yoh, Kanke, Kazunari, Kobayashi, Kiyonori, Hirai, Fumihito, Watanabe, Kenji, Mizusawa, Hidehiro, Kishida, Shuji, Miura, Yoshiharu, Ohta, Akira, Kajioka, Toshifumi, and Hibi, Toshifumi

Published
2022
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2. AJM300 (carotegrast methyl), an oral antagonist of α4-integrin, as induction therapy for patients with moderately active ulcerative colitis: a multicentre, randomised, double-blind, placebo-controlled, phase 3 study

Author

Matsuoka, Katsuyoshi, primary, Watanabe, Mamoru, additional, Ohmori, Toshihide, additional, Nakajima, Koichi, additional, Ishida, Tetsuya, additional, Ishiguro, Yoh, additional, Kanke, Kazunari, additional, Kobayashi, Kiyonori, additional, Hirai, Fumihito, additional, Watanabe, Kenji, additional, Mizusawa, Hidehiro, additional, Kishida, Shuji, additional, Miura, Yoshiharu, additional, Ohta, Akira, additional, Kajioka, Toshifumi, additional, Hibi, Toshifumi, additional, Motoya, Satoshi, additional, Maemoto, Atsuo, additional, Fujiya, Mikihiro, additional, Ashida, Toshifumi, additional, Goto, Mitsuru, additional, Matsumoto, Takayuki, additional, Suzuki, Yasuo, additional, Hamahata, Yukihiro, additional, Nakagawa, Tomoo, additional, Kato, Naoya, additional, Kato, Jun, additional, Endo, Yutaka, additional, Suzuki, Ryoichi, additional, Matsuda, Koichiro, additional, Ohmiya, Naoki, additional, Katsushima, Shinji, additional, Hosomi, Shuhei, additional, Tarumi, Ken-ichi, additional, Watanabe, Chiyuki, additional, Saito, Mitsuru, additional, Yokoyama, Yuichiro, additional, Inaba, Tomoki, additional, Sakata, Yasuhisa, additional, Hongo, Hitoshi, additional, Shibuya, Tomoyoshi, additional, Kawakami, Kazuhiko, additional, Kakuta, Yoichi, additional, Irisawa, Atsushi, additional, Yoshimura, Naoki, additional, Fukuda, Katsuyuki, additional, Shirai, Takayuki, additional, Ichikawa, Hitoshi, additional, Nagata, Junko, additional, Suzuki, Takayoshi, additional, Yokoyama, Kaoru, additional, Tomidokoro, Takashi, additional, Kojima, Yuichiro, additional, Yamada, Masahiro, additional, Yamamoto, Hideko, additional, Yamamoto, Takayuki, additional, Horiki, Noriyuki, additional, Obata, Hirozumi, additional, Inoue, Satoko, additional, Tanaka, Shinji, additional, Toyokawa, Tatsuya, additional, Kunihiro, Masaki, additional, Hisabe, Takashi, additional, Ogata, Shinichi, additional, Takeshima, Fuminao, additional, Matsushima, Kayoko, additional, Matsuhashi, Nobuyuki, additional, Sakuraba, Hirotake, additional, Iwabuchi, Masahiro, additional, Tsuchiya, Akihiko, additional, Uchiyama, Kan, additional, Kanai, Takanori, additional, Nakamura, Masanao, additional, Yokoyama, Tadashi, additional, Hida, Nobuyuki, additional, Mitsuyama, Keiichi, additional, Osada, Taro, additional, Hiraoka, Sakiko, additional, Tsuzuki, Tomoyuki, additional, Masuo, Takashige, additional, Hokari, Ryota, additional, Kobayashi, Taku, additional, Saruta, Masayuki, additional, Araki, Masao, additional, Araki, Hiroshi, additional, Shimizu, Masahito, additional, Kikuchi, Masakazu, additional, Nishikawa, Takahiro, additional, Takedatsu, Hidetoshi, additional, Aoyagi, Kunihiko, additional, Ochiai, Toshiaki, additional, Toda, Nobuo, additional, Mizokami, Yuji, additional, Nagahori, Masakazu, additional, Matsueda, Kazuhiro, additional, Kino, Hitoshi, additional, Kanamori, Akira, additional, Suzuki, Tsunehiro, additional, Sakurai, Toshiharu, additional, Kudo, Masatoshi, additional, Kitano, Atsuo, additional, Hisamatsu, Tadakazu, additional, Kumagai, Shinji, additional, Ninomiya, Tomoyuki, additional, Mori, Kenichiro, additional, Yoshida, Shun-ichi, additional, and Goto, Mitsuhide, additional

Published
2022
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4. Su1632 Don't You Worry About Neglecting a Large Defect After Endoscopic Submucosal Dissection of Colorectal Tumors? ; Development of Our Original Device for Purse-String-Ligature Not to Use a Special Endoscope for

Author

Hiraga, Yuko, primary, Shinagawa, Kei, additional, Komichi, Daisuke, additional, Sasaki, Tamito, additional, Hiramoto, Tomoki, additional, Kitamoto, Mikiya, additional, Watanabe, Chiyuki, additional, Yamada, Hiroyasu, additional, and Sumioka, Masaaki, additional

Published
2016
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5. The Relationship between Gastric Secretion and Type of Early Gastric Carcinoma

Author

Yoshihara, Masaharu, Haruma, Ken, Sumii, Koji, Watanabe, Chiyuki, Kiyohira, Kuninushi, Kawaguchi, Hiroyuki, Tanaka, Shinji, and Kajiyama, Goro

Subjects
digestive, oral, and skin physiology, Gastric carcinoma, Serum gastrin, digestive system, digestive system diseases, Gastric acid secretion, Serum pepsinogen I
Abstract

To determine the relationship between gastric secretion and gastric carcinoma, we investigated gastric acid secretion and the fasting serum levels of pepsinogen I and gastrin in 50 Japanese patients with early gastric carcinoma. After the histological and macroscopic type of carcinoma had been determined, results were compared with findings in 50 Japanese control subjects whose gastric mucosa was endoscopically normal. The maximum gastric acid secretion and fasting levels of serum pepsinogen I were significantly lower in intestinal type gastric carcinoma than in diffuse type carcinoma and in the controls. They were also significantly lower in the non-ulcerative (elevated or flat) type than in the ulcerative (depressed) type of carcinoma. The serum gastrin levels in patients with early gastric carcinoma of either the intestinal or diffuse type were higher than those in the control subjects, though the difference was not significant. Gastric acid secretion and serum pepsinogen I levels were related with both the histological and macroscopic types of gastric carcinoma. These findings suggest that the serum pepsinogen I level might be useful as a maker for early gastric carcinoma of the intestinal type.

Published
1995

8. Multicenter prospective study for clinical and endoscopic efficacies of leukocytapheresis therapy in patients with ulcerative colitis

Author

Okuyama, Yusuke, primary, Andoh, Akira, additional, Nishishita, Masakazu, additional, Fukunaga, Ken, additional, Kamikozuru, Koji, additional, Yokoyama, Yoko, additional, Ueno, Yoshitaka, additional, Tanaka, Shinji, additional, Kuge, Hiroyuki, additional, Yoshikawa, Syusaku, additional, Sugahara, Atsushi, additional, Anami, Emi, additional, Munetomo, Yoshinori, additional, Watanabe, Chiyuki, additional, Fujiyama, Yoshihide, additional, and Matsumoto, Takayuki, additional

Published
2013
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9. Sa1585 The Corresponding Rate of Magnification Observation Findings of Narrow Band Imaging (NBI) and Flexible Spectral Imaging Color Enhancement (FICE) in Gastric Tumors and in Colorectal Lesions

Author

Hiraga, Yuko, primary, Sumioka, Masaaki, additional, Hiramoto, Tomoki, additional, Akagi, Morihisa, additional, Komichi, Daisuke, additional, Kuwada, Yukio, additional, Kitamoto, Mikiya, additional, Watanabe, Chiyuki, additional, and Nishisaka, Takashi, additional

Published
2012
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10. A case of Pneumocystis pneumonia during receiving medication by steroid for autoimmune hepatitis

Author

Tatsukawa, Yumiko, primary, Kitamoto, Mikiya, additional, Kunihara, Sayoko, additional, Igawa, Atsushi, additional, Komichi, Daisuke, additional, Kuwada, Yukio, additional, Hiramoto, Tomoki, additional, Hiraga, Yuko, additional, Akagi, Morihisa, additional, Watanabe, Chiyuki, additional, Sumioka, Masaaki, additional, Kajihara, Toshiki, additional, and Nishisaka, Takashi, additional

Published
2012
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11. Mo1538 Comparison With Narrow Band Imaging (NBI) Magnification and Flexible Spectral Imaging Color Enhancement (FICE) Magnification in the Invasion Depth Diagnosability of Colorectal Tumors

Author

Hiraga, Yuko, primary, Sumioka, Masaaki, additional, Hiramoto, Tomoki, additional, Akagi, Morihisa, additional, Tatsukawa, Yumiko, additional, Igawa, Atsushi, additional, Matsumoto, Yoko, additional, Komichi, Daisuke, additional, Kuwada, Yukio, additional, Kitamoto, Mikiya, additional, Watanabe, Chiyuki, additional, and Nishisaka, Takashi, additional

Published
2011
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12. S1621: Comparison Between Avascular-Area of NBI Magnification and Type V Pit Pattern for Invasion Depth Diagnosis of Colorectal Tumors

Author

Hiraga, Yuko, primary, Sumioka, Masaaki, additional, Akagi, Morihisa, additional, Hiramoto, Tomoki, additional, Matsumoto, Yoko, additional, Igawa, Atsushi, additional, Hayashi, Ryohei, additional, Kitamoto, Mikiya, additional, Watanabe, Chiyuki, additional, Yamada, Hiroyasu, additional, Imagawa, Masaru, additional, and Nishizaka, Takashi, additional

Published
2010
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15. A case of senile woman diagnosed with autoimmune hepatitis

Author

Hayashi, Ryohei, primary, Kitamoto, Mikiya, additional, Noda, Ikue, additional, Watanabe, Chiyuki, additional, Yamada, Hiroyasu, additional, Imagawa, Masaru, additional, Matsumoto, Yoko, additional, Tanaka, Mio, additional, Kodama, Michiyo, additional, Hiramoto, Tomoki, additional, Akagi, Morihisa, additional, Sumioka, Masaaki, additional, and Nishisaka, Takashi, additional

Published
2009
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17. Radiofrequency Ablation in the Treatment of Small Hepatocellular Carcinomas:Comparison of the Radiofrequency Effect With and Without Chemoembolization

Author

Kitamoto, Mikiya, primary, Imagawa, Masaru, additional, Yamada, Hiroyasu, additional, Watanabe, Chiyuki, additional, Sumioka, Masaaki, additional, Satoh, Osamu, additional, Shimamoto, Masaru, additional, Kodama, Michiyo, additional, Kimura, Shojiro, additional, Kishimoto, Keiko, additional, Okamoto, Yuzo, additional, Fukuda, Yasuhiko, additional, and Dohi, Kiyohiko, additional

Published
2003
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29. Therapeutic Evaluation of Combination Therapy using C-425, Human Native Immunoglobulin Liquid Preparation for i.v. Administration, with Antibiotics in Severe Infections in the Field of Surgery

Author

MISHIMA, Yoshio, primary, INOUE, Toshinao, additional, HAYASAKA, Hiroshi, additional, TOTSUKA, Morio, additional, EBATA, Toshiaki, additional, MOTOKI, Ryoichi, additional, INOUE, Hitoshi, additional, ENDO, Yukio, additional, TAMAKUMA, Shoetsu, additional, IMAI, Jun, additional, MORIOKA, Yasuhiko, additional, ISHIYAMA, Masaru, additional, WATANABE, Chiyuki, additional, KIMURA, Kozaburo, additional, KURIHARA, Shigekatsu, additional, NAKAZIMA, Atsushi, additional, ISHIBIKI, Kyuya, additional, AIKAWA, Naoki, additional, TAKAGI, Hiroshi, additional, TAIRA, Noboru, additional, OZAWA, Kazue, additional, SHIMAHARA, Yasuyuki, additional, MORI, Takesada, additional, KANBAYASHI, Junichi, additional, SAITO, Yoichi, additional, and NISHIYAMA, Hiroyasu, additional

Published
1990
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31. The Relationship between Gastric Secretion and Type of Early Gastric Carcinoma

Author

Yoshihara, Masaharu, Haruma, Ken, Sumii, Koji, Watanabe, Chiyuki, Kiyohira, Kuninushi, Kawaguchi, Hiroyuki, Tanaka, Shinji, Kajiyama, Goro, Yoshihara, Masaharu, Haruma, Ken, Sumii, Koji, Watanabe, Chiyuki, Kiyohira, Kuninushi, Kawaguchi, Hiroyuki, Tanaka, Shinji, and Kajiyama, Goro

Abstract

To determine the relationship between gastric secretion and gastric carcinoma, we investigated gastric acid secretion and the fasting serum levels of pepsinogen I and gastrin in 50 Japanese patients with early gastric carcinoma. After the histological and macroscopic type of carcinoma had been determined, results were compared with findings in 50 Japanese control subjects whose gastric mucosa was endoscopically normal. The maximum gastric acid secretion and fasting levels of serum pepsinogen I were significantly lower in intestinal type gastric carcinoma than in diffuse type carcinoma and in the controls. They were also significantly lower in the non-ulcerative (elevated or flat) type than in the ulcerative (depressed) type of carcinoma. The serum gastrin levels in patients with early gastric carcinoma of either the intestinal or diffuse type were higher than those in the control subjects, though the difference was not significant. Gastric acid secretion and serum pepsinogen I levels were related with both the histological and macroscopic types of gastric carcinoma. These findings suggest that the serum pepsinogen I level might be useful as a maker for early gastric carcinoma of the intestinal type.

37. [Usefulness of ultrasonography for diagnosis and treatment in case of superior mesenteric artery (SMA) syndrome].

Author

Kodama M, Yamada H, Matsumoto Y, Hayashi R, Noda I, Tanaka M, Hiramoto T, Akagi M, Watanabe C, Kitamoto M, Sumioka M, and Imagawa M

Subjects
Adult, Humans, Male, Superior Mesenteric Artery Syndrome therapy, Ultrasonography, Superior Mesenteric Artery Syndrome diagnostic imaging
Abstract

A 37-year-old man, who had been admitted to another facility because of integration dysfunction syndrome suffered from postprandial epigastric pain, vomiting and weight loss. He was referred to our hospital for further examinations and treatment. Ultrasound examination revealed gastric and duodenal dilatation, reduction of the distance between the superior mesenteric artery (SMA) and aorta and to-and-fro movement in his duodenum, suggesting SMA syndrome. Computed tomography and upper gastrointestinal tract examination also showed findings typical of SMA syndrome. We measured the SMA-aorta distance and the passage of duodenal contents in various body positions using ultrasound. He had to-and-fro movements in his duodenum in a supine, sitting, and left recumbent position. However, when examined in the right recumbent position, the SMA-aorta distance became longest, and intestinal juice flowed from the duodenum to the jejunum. He underwent postural therapy, maintaining a right recumbent position for 30 minutes after every meal, which improved his clinical symptoms.

Published
2010

38. [Large hepatocellular carcinoma successfully treated with transarterial chemoembolization using cisplatin].

Author

Harada W, Kitamoto M, Hayashi R, Noda I, Hiramoto T, Akagi M, Watanabe C, Yamada H, Sumioka M, Imagawa M, and Okimoto T

Subjects
Aged, 80 and over, Humans, Male, Antineoplastic Agents administration & dosage, Carcinoma, Hepatocellular therapy, Chemoembolization, Therapeutic methods, Cisplatin administration & dosage, Liver Neoplasms therapy
Abstract

A 83-year-old man was admitted to our hospital with a large hepatic tumor located in lateral segment. Alpha-fetoprotein was 7ng/ml, and protein induced by vitamin K deficiency and antagonist-II (PIVKA-II) was 50792mAU/ml. The tumor was diagnosed as hepatocellular carcinoma (HCC) by angiographically assisted CT. No ascites was detected and major serological findings were T-Bil 0.7mg/dl, Alb 4.2g/dl, and PT 129%. Because of advanced age and a history of heart disease, he was treated with transarterial chemoembolization using cisplatin (Lip-TACE). The total dose was 128mg of cisplatin and 15ml of lipiodol. No adverse effects appeared. After the third session of Lip-TACE, the levels of PIVKA-II became negative and continued within the normal range for 26 months. We confirmed a decrease of HCC with lipiodol accumulation by abdominal CT, and the response rate was PR. He has been well for 3 years since the first Lip-TACE procedure.

Published
2009

39. Radiofrequency ablation in the treatment of small hepatocellular carcinomas: comparison of the radiofrequency effect with and without chemoembolization.

Author

Kitamoto M, Imagawa M, Yamada H, Watanabe C, Sumioka M, Satoh O, Shimamoto M, Kodama M, Kimura S, Kishimoto K, Okamoto Y, Fukuda Y, and Dohi K

Subjects
Aged, Carcinoma, Hepatocellular diagnostic imaging, Combined Modality Therapy, Female, Humans, Liver Neoplasms diagnostic imaging, Male, Middle Aged, Postoperative Complications epidemiology, Tomography, X-Ray Computed, Carcinoma, Hepatocellular therapy, Catheter Ablation adverse effects, Chemoembolization, Therapeutic adverse effects, Liver Neoplasms therapy
Abstract

Objective: The purpose of this study was to determine whether a combination of transcatheter arterial chemoembolization using doxorubicin and radiofrequency ablation can increase tumor destruction compared with radiofrequency alone in the treatment for hepatocellular carcinoma. SUBJECTS AND METHODS. Twenty-one patients with 26 nodules smaller than 3 cm in diameter were treated with radiofrequency ablation. Of these, 10 nodules were treated with a combination of radiofrequency ablation and chemoembolization using doxorubicin. All nodules were evaluated for size of induced coagulation, local recurrence, and complication., Results: The therapeutic areas averaged 27.6 x 22.3 mm using an electrode with a 2-cm tip and 37.2 x 29.1 mm using an electrode with a 3-cm tip. With respect to the results for 14 nodules treated using an electrode with a 3-cm tip with or without chemoembolization, the greatest dimension of the area coagulated by combined therapy was significantly larger (longest axis dimension, 39.9 +/- 4.4 mm; shortest axis dimension, 32.3 +/- 5.2 mm; n = 7 nodules) than areas without chemoembolization (longest axis dimension, 34.6 +/- 2.6 mm; shortest axis dimension, 26.0 +/- 3.3 mm; n = 7 nodules) (longest and shortest axis dimensions, p < 0.05). No recurrence occurred in the nodules smaller than 2 cm in diameter. Among the nodules larger than 2 cm in diameter, one local recurrence was observed in seven nodules treated by combined therapy, while two local recurrences were observed in seven nodules treated by radiofrequency alone. Minor complications developed in three patients, two with persistent high fever and one with biliary stenosis., Conclusion: The combination of radiofrequency ablation and transcatheter arterial chemoembolization using doxorubicin markedly increased the extent of induced coagulation compared with radiofrequency alone, despite a small number of patients and the preliminary nature of this study.

Published
2003
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