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1. Corporal Skip Metastases in Penile Squamous Cell Carcinoma: An Unknown and Distinct Pattern of Spread with Poor Prognosis

Author

Elst, Laura, Vreeburg, Manon T.A., de Vries, Hielke Martijn, Vandermaesen, Kaat, Murphy, Titus, Churchill, James, Fallara, Giuseppe, Sanchez, Darren, Falcone, Marco, Garcia-Perdomo, Herney Andres, Pettaway, Curtis, Hakenberg, Oliver, Johnstone, Peter, Spiess, Philippe E., Muneer, Asif, Sangar, Vijay, Parnham, Arie, Ayres, Benjamin, Watkin, Nick, Brouwer, Oscar R., and Albersen, Maarten

Published
2024
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3. Predicting Limited Survival Following Inguinal Lymph Node Dissection in Penile Cancer: Should We Revisit the Goals of Care?

Author

Hugar, Lee A., Peak, Taylor C., Naqvi, Mahrukh, Kim, Youngchul, Bandini, Marco, Pederzoli, Filippo, Marandino, Laura, Albersen, Maarten, Roussel, Eduard, Zhu, Yao, Ye, Ding-Wei, Ornellas, Antonio A., Catanzaro, Mario, Hakenberg, Oliver W., Heidenreich, Axel, Haidl, Friederike, Watkin, Nick, Ager, Michael, Briganti, Alberto, Salvioni, Roberto, Chakiryan, Nicholas H., Montorsi, Francesco, Necchi, Andrea, and Spiess, Philippe E.

Published
2023
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6. Association Between Human Papillomavirus Infection and Outcome of Perioperative Nodal Radiotherapy for Penile Carcinoma

Author

Bandini, Marco, Ross, Jeffrey S., Zhu, Yao, Ye, Ding-Wei, Ornellas, Antonio A., Watkin, Nick, Ayres, Benjamin A., Hakenberg, Oliver W., Heidenreich, Axel, Salvioni, Roberto, Catanzaro, Mario, Raggi, Daniele, Giannatempo, Patrizia, Marandino, Laura, Haidl, Friederike, Pederzoli, Filippo, Briganti, Alberto, Montorsi, Francesco, Chipollini, Juan, Azizi, Mounsif, De Meerleer, Gert, Brouwer, Oscar R., Grass, G. Daniel, Johnstone, Peter A., Albersen, Maarten, Spiess, Philippe E., and Necchi, Andrea

Published
2021
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9. International case series of metastasis to penis

Author

Youssef, Irini, primary, Elst, Laura, additional, Watkin, Nick, additional, de Vries, Hielke Martijn, additional, Brouwer, Oscar, additional, Protzel, Chris, additional, Ayres, Benjamin, additional, Albersen, Maarten, additional, Spiess, Philippe E., additional, and Johnstone, Peter A. S., additional

Published
2023
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14. Erstvorstellung des Pentafecta-Scores als Qualitätsinstrument der Outcome-Bewertung einer chirurgischen Primärtherapie an Patienten mit Peniskarzinom

Author

May, Matthias, primary, Lebentrau, Steffen, primary, Ayres, Ben, primary, Spiess, Philippe E., primary, Watkin, Nick, additional, Albersen, Maarten, additional, Protzel, Chris, additional, Chahoud, Jad, additional, Brouwer, Oscar R., additional, Pettaway, Curtis A., additional, Pagliaro, Lance C., additional, Necchi, Andrea, additional, and Hakenberg, Oliver W., additional

Published
2023
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15. List of Contributors

Author

Abdel-Aal, Ahmad R., primary, Allan, Jonathan A., additional, Emmanuel, Anthony, additional, Fahmy, Mohamed A Baky, additional, K'Odhiambo, Atieno Kili, additional, and Watkin, Nick, additional

Published
2020
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16. The Goal of Achieving High-Quality Surgical First-Line Therapy in Patients with Penile Cancer Is Important; However, Some Collective Efforts Are Still Required in Order to Reach It. Comment on Brassetti et al. Combined Reporting of Surgical Quality and Cancer Control after Surgical Treatment for Penile Tumors with Inguinal Lymph Node Dissection: The Tetrafecta Achievement. Curr. Oncol. 2023, 30, 1882–1892

Author

May, Matthias, primary, Lebentrau, Steffen, additional, Ayres, Ben, additional, Albersen, Maarten, additional, Protzel, Chris, additional, Chahoud, Jad, additional, Brouwer, Oscar R., additional, Pettaway, Curtis A., additional, Pagliaro, Lance C., additional, Necchi, Andrea, additional, Watkin, Nick, additional, Hakenberg, Oliver W., additional, and Spiess, Philippe E., additional

Published
2023
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17. Concomitant vs Staged Therapeutic Inguinal Lymphadenectomy in Clinically Node Positive Penile Squamous Cell Carcinoma: Does It Make a Difference?

Author

Huelster, Heather L., primary, Chang, Andrew, additional, Rose, Kyle M., additional, Bandini, Marco, additional, Albersen, Maarten, additional, Roussel, Eduard, additional, Chipollini, Juan, additional, Zhu, Yao, additional, Ye, Ding-Wei, additional, Ornellas, Antonio A., additional, Catanzaro, Mario, additional, Marandino, Laura, additional, Pederzoli, Filippo, additional, Hakenberg, Oliver W., additional, Heidenreich, Axel, additional, Haidl, Friederike, additional, Watkin, Nick, additional, Ager, Michael, additional, Ahmed, Mohamed E., additional, Karnes, Jeffrey R., additional, Briganti, Alberto, additional, Kim, Youngchul, additional, Montorsi, Francesco, additional, Necchi, Andrea, additional, and Spiess, Philippe E., additional

Published
2023
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20. Rare and Complex Urology: Clinical Overview of ERN eUROGEN

Author

Oomen, Loes, Leijte, Erik, Shilhan, Darren E., Battye, Michelle, Feitz, Wout F.J., Waltregny, David, Van der Aa, Frank, Spinoit, Anne-Françoise, Rösch, Wolfgang H., Schmiedeke, Eberhard, Fisch, Margit, Märzheuser, Stefanie, Gosemann, Jan-Hendrik, Hubertus, Jochen, Rawashdeh, Yazan, Thorup, Jorgen, Heloury, Yves, Leva, Ernesto, Mancini, Mariangela, Bagolan, Pietro, Sacco, Emilio, Verkauskas, Gilvydas, Feitz, Wout, Sloots, Cornelius, Czauderna, Piotr, Mauricio, Maria, Holmdahl, Gundela, Abrahamsson, Kate, Thomas, Kay, Cardozo, Linda, Chapple, Christopher, Sangar, Vijay, Greenwell, Tamsin, Watkin, Nick, Bujons Tur, Anna, Lozano Ortega, Jose, Pérez-Valderrama, Maria Begoña, Gutierrez Baños, Jose, Garcia Aparicio, Luis, Lopez, Manuel, Romero Otero, Javier, Lopez Pereira, Pedro, Herranz Amo, Felipe, Oswald, Josef, Abols, Valts, Frobe, Ana, Judit Molnar, Maria, Goergen, Martine, Dalmas, Miriam, Lovrecic, Luca, and ERN eUROGEN, [missing]

Subjects
eUROGEN, European level, Health Personnel, Urology, education, 030232 urology & nephrology, European Reference Network, Disease, HYPOSPADIAS, Collaboration, Complex conditions, Rare, Rare diseases, 03 medical and health sciences, 0302 clinical medicine, Medicine and Health Sciences, medicine, Humans, EPIDEMIOLOGY, In patient, Patient summary, Retrospective Studies, Data collection, Settore MED/24 - UROLOGIA, business.industry, Retrospective cohort study, medicine.disease, Reconstructive and regenerative medicine Radboud Institute for Molecular Life Sciences [Radboudumc 10], Data extraction, 030220 oncology & carcinogenesis, Medical emergency, Diagnosis code, business
Abstract

Background: In 2017, the European Commission launched 24 European Reference Networks (ERNs). ERN eUROGEN is the network for urorectogenital diseases and complex conditions, and started with 29 full member healthcare providers (HCPs) in 11 countries. It then covered 19 different disease areas distributed over three work -streams (WSs). Objective: To provide an overview and identify challenges in data collection at European level of the ERN eUROGEN patient population treated by HCPs in the network. Design, setting, and participants: A retrospective cohort study was conducted of the 29 HCPs who were full members between 2013 and 2019. Outcome measurements and statistical analysis: Data were extracted from the original HCP applications and the ERN continuous monitoring system. Patient volumes, new patient numbers, and procedures were compared between different WSs, countries, and HCPs. Discrepancies between monitoring and application data were identified. Results and limitations: Between 2013 and 2019, 122 040 patients required long-term care within the 29 HCPs. The volume of patients treated and procedures undertaken per year increased over time. Large discrepancies were found between patient numbers contained in the application forms and those reported in the continuous monitoring system (0-1357% deviation). Conclusions: Patient numbers and procedures increased across ERN eUROGEN HCPs. Reliable data extraction appeared challenging, illustrated by the patient volume dis-crepancies between application forms and the continuous monitoring data. Improved disease definitions, re-evaluation of affiliated HCPs, and valid data extraction are needed for future improvements. Patient summary: We analysed the patient population with rare urorectogenital dis-eases or complex conditions within the ERN eUROGEN network between 2013 and 2019. Clinical activity was found to increase, but differences in patient numbers were evident between healthcare providers. In order to acquire valid patient numbers, both improved definitions of diagnostic codes and greater insight into the data-gathering process are required. (c) 2021 The Authors. Published by Elsevier B.V. on behalf of European Association of Urology. This is an open access article under the CC BY license (http://creativecommons. org/licenses/by/4.0/).

Published
2022

22. Longitudinal cohort analysis of patients with metastatic penile cancer treated in a large quaternary academic centre.

Author

Liu, Wing K, Patel, Reena, Crawford, Ruairidh, Ayres, Benjamin, Watkin, Nick, Tree, Alison, Pickering, Lisa, Patel, Hiten RH, and Ashfar, Mehran

Abstract

Objective: This study aimed to provide real-world data on the multidisciplinary management of metastatic penile squamous-cell carcinoma (mpSCC) patients and their survival outcomes, particularly those who receive best supportive care (BSC). Methods: A retrospective analysis of 1720 patients, managed via a supra-regional penile-specialist multidisciplinary team was conducted between January 2006 and May 2020. Results: A total of 101 patients (median age 63 years; interquartile range 56–72 years; 73% ECOG 0/1) were included. Of these, 32% (32/101) had previously received adjuvant chemotherapy prior to metastatic recurrence, 58% (59/101) received chemotherapy and 42% (42/101) received BSC. Further, 17% (17/101) received second-line systemic therapy, and 3% (3/101) received third-line systemic therapy. For first-line systemic-therapy, there was a 46% (27/59) clinical benefit rate (CBR), with 9% (5/59) complete response, 15% (9/59) partial response and 22% (13/59) stable disease. Patients receiving second-line therapy (n =17) had a 29% (5/17) CBR. Median progression-free survival for first- and second-line treatment was 3.2 and 2.2 months, respectively. Median overall survival (mOS) for all patients was 6.2 months. mOS for first-line chemotherapy, second-line chemotherapy and BSC patients was 7.2, 4.5 and 2.0 months, respectively. Conclusions: First-line platinum-based chemotherapy is associated with notable response rates in mpSCC patients. Agents with better response rates are needed urgently potentially in combination with platinum-based chemotherapy. Level of evidence: Level 2b. [ABSTRACT FROM AUTHOR]

Published
2023
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24. The Penis

Author

Magrill, Dan, Watkin, Nick, Bott, Simon, editor, Patel, Uday, editor, Djavan, Bob, editor, and Caroll, Peter R., editor

Published
2012
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26. PD51-11 CONCOMITANT VS STAGED LYMPHADENECTOMY IN CLINICALLY NODE-POSITIVE PENILE SQUAMOUS CELL CARCINOMA: RECURRENCE PATTERNS AND SURVIVAL OUTCOMES

Author

Huelster, Heather, primary, Bandini, Marco, additional, Brouwer, Oscar, additional, Albersen, Maarten, additional, Roussel, Eduard, additional, de Vries, Hielke, additional, Chipollini, Juan, additional, Azizi, Mounsif, additional, Zhu, Yao, additional, Ye, Ding-Wei, additional, Ornellas, Antonio, additional, Catanzaro, Mario, additional, Marandino, Laura, additional, Hakenberg, Oliver, additional, Heidenreich, Axel, additional, Haidl, Friederike, additional, Watkin, Nick, additional, Ager, Michael, additional, Ahmed, Mohamed, additional, Karnes, Jeffrey, additional, Briganti, Alberto, additional, Salvioni, Roberto, additional, Montorsi, Francesco, additional, Necchi, Andrea, additional, and Spiess, Philippe, additional

Published
2022
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27. CorrespondenceExtramammary Paget disease in a patient with hidradenitis suppurativa.

Author

McGrath, Conn, Corso, Roberto, Williams, Andrew, Watkin, Nick, Calonje, Eduardo, Rashidghamat, Ellie, and Roche, Helena Malhomme de la

Subjects
HIDRADENITIS suppurativa, INFORMED consent (Medical law), IRON deficiency anemia
Abstract

Dear Editor, Extramammary Paget disease (EMPD) is a rare intraepithelial adenocarcinoma that usually affects areas with abundant apocrine glands, such as anogenital or axillary skin. To our knowledge, EMPD has never before been diagnosed in a patient with comorbid hidradenitis suppurativa (HS) or on adalimumab therapy. We present a case of EMPD diagnosed incidentally in excised skin from a patient who underwent surgical management of extensive HS of the groin. [Extracted from the article]

Published
2023
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28. Clinicopathological predictors of finding additional inguinal lymph node metastases in penile cancer patients after positive dynamic sentinel node biopsy: a European multicentre evaluation

Author

de Vries, Hielke M., primary, Lee, Hack Jae, additional, Lam, Wayne, additional, Djajadiningrat, Rosa S., additional, Ottenhof, Sarah R., additional, Roussel, Eduard, additional, Kroon, Bin Klaas, additional, de Jong, Igle Jan, additional, Oliveira, Pedro, additional, Alnajjar, Hussain M., additional, Albersen, Maarten, additional, Muneer, Asif, additional, Sangar, Vijay, additional, Parnham, Arie, additional, Ayres, Benjamin, additional, Watkin, Nick, additional, Horenblas, Simon, additional, Stuiver, Martijn M., additional, and Brouwer, Oscar R., additional

Published
2022
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29. Risk factors and survival outcomes for upstaging after inguinal lymph node dissection for cN1 penile squamous cell carcinoma

Author

Chakiryan, Nicholas H, primary, Dahmen, Aaron, additional, Bandini, Marco, additional, Pederzoli, Filippo, additional, Marandino, Laura, additional, Albersen, Maarten, additional, Roussel, Eduard, additional, Zhu, Yao, additional, Ye, Ding-Wei, additional, Ornellas, Antonio A, additional, Catanzaro, Mario, additional, Hakenberg, Oliver W, additional, Heidenreich, Axel, additional, Haidl, Friederike, additional, Watkin, Nick, additional, Ager, Michael, additional, Briganti, Alberto, additional, Salvioni, Roberto, additional, Montorsi, Francesco, additional, Necchi, Andrea, additional, and Spiess, Philippe E., additional

Published
2021
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31. Reply by Authors

Author

Chakiryan, Nicholas H., primary, Dahmen, Aaron, additional, Bandini, Marco, additional, Pederzoli, Filippo, additional, Marandino, Laura, additional, Albersen, Maarten, additional, Roussel, Eduard, additional, Zhu, Yao, additional, Ye, Ding-Wei, additional, Ornellas, Antonio A., additional, Catanzaro, Mario, additional, Hakenberg, Oliver W., additional, Heidenreich, Axel, additional, Haidl, Friederike, additional, Watkin, Nick, additional, Ager, Michael, additional, Chahoud, Jad, additional, Briganti, Alberto, additional, Salvioni, Roberto, additional, Montorsi, Francesco, additional, Necchi, Andrea, additional, and Spiess, Philippe E., additional

Published
2021
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33. Patterns of Recurrence following Inguinal Lymph Node Dissection for Penile Cancer: Optimizing Surveillance Strategies

Author

Chakiryan, Nicholas H., primary, Dahmen, Aaron, additional, Bandini, Marco, additional, Pederzoli, Filippo, additional, Marandino, Laura, additional, Albersen, Maarten, additional, Roussel, Eduard, additional, Zhu, Yao, additional, Ye, Ding-Wei, additional, Ornellas, Antonio A., additional, Catanzaro, Mario, additional, Hakenberg, Oliver W., additional, Heidenreich, Axel, additional, Haidl, Friederike, additional, Watkin, Nick, additional, Ager, Michael, additional, Chahoud, Jad, additional, Briganti, Alberto, additional, Salvioni, Roberto, additional, Montorsi, Francesco, additional, Necchi, Andrea, additional, and Spiess, Philippe E., additional

Published
2021
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35. PD53-01 FACTORS ASSOCIATED WITH ADDITIONAL TUMOUR-BEARING LYMPH NODES AT COMPLETION ILND AFTER POSITIVE DSNB FOR PENILE CANCER STAGING: A EUROPEAN MULTICENTRE EVALUATION

Author

de Vries, Hielke, primary, Lee, Hack, additional, Roussel, Eduard, additional, Kroon, Bin, additional, de Jong, Igle, additional, Albersen, Maarten, additional, Muneer, Asif, additional, Sangar, Vijay, additional, Parnham, Arie, additional, Ayres, Benjamin, additional, Watkin, Nick, additional, Horenblas, Simon, additional, Stuiver, Martijn, additional, and Brouwer, Oscar, additional

Published
2021
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36. PD53-10 PREDICTING LIMITED SURVIVAL FOR PATIENTS WITH PENILE CANCER UNDERGOING INGUINAL LYMPH NODE DISSECTION

Author

Hugar, Lee, primary, Chakiryan, Nicholas, additional, Naqvi, Mahrukh, additional, Kim, Youngchul, additional, Bandini, Marco, additional, Pederzoli, Filippo, additional, Marandino, Laura, additional, Albersen, Maarten, additional, Roussel, Eduard, additional, Chipollini, Juan, additional, Zhu, Yao, additional, Ye, Ding-Wei, additional, Ornellas, Antonio, additional, Catanzaro, Mario, additional, Hakenberg, Oliver, additional, Heidenreich, Axel, additional, Haidl, Friederike, additional, Watkin, Nick, additional, Ager, Michael, additional, Ahmed, Mohamed, additional, Karnes, Jeffrey, additional, Briganti, Alberto, additional, Salvioni, Roberto, additional, Montorsi, Francesco, additional, Necchi, Andrea, additional, and Spiess, Philippe, additional

Published
2021
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41. Contemporary Treatment Patterns and Outcomes for Patients with Penile Squamous Cell Carcinoma: Identifying Management Gaps to Promote Multi-institutional Collaboration

Author

Bandini, Marco, Zhu, Yao, Ye, Ding-Wei, Ornellas, Antonio A., Watkin, Nick, Ayres, Benjamin, Hakenberg, Oliver W., Heidenreich, Axel, Raggi, Daniele, Giannatempo, Patrizia, Marandino, Laura, Haidl, Friederike, Pederzoli, Filippo, Briganti, Alberto, Montorsi, Francesco, Chipollini, Juan, Azizi, Mounsif, De Meerleer, Gert, Brouwer, Oscar R., Grass, G. Daniel, Johnstone, Peter A., Albersen, Maarten, Spiess, Philippe E., and Necchi, Andrea

Published
2021
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50. Long‐term multicentre experience of adjuvant radiotherapy for pN3 squamous cell carcinoma of the penis

Author

Ager, Michael, primary, Njoku, Kelechi, additional, Serra, Maria, additional, Robinson, Angus, additional, Pickering, Lisa, additional, Afshar, Mehran, additional, Vyas, Lona, additional, Eardley, Ian, additional, Kayes, Oliver, additional, Elmamoun, Mamoun, additional, Khoo, Vincent, additional, Ayres, Benjamin, additional, Henry, Ann, additional, Watkin, Nick, additional, and Tree, Alison C., additional

Published
2020
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