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1. Protein intake and cancer: an umbrella review of systematic reviews for the evidence-based guideline of the German Nutrition Society

Author

Kühn, Tilman, Kalotai, Nicole, Amini, Anna M., Haardt, Julia, Lehmann, Andreas, Schmidt, Annemarie, Buyken, Anette E., Egert, Sarah, Ellinger, Sabine, Kroke, Anja, Lorkowski, Stefan, Louis, Sandrine, Schulze, Matthias B., Schwingshackl, Lukas, Siener, Roswitha, Stangl, Gabriele I., Watzl, Bernhard, Zittermann, Armin, and Nimptsch, Katharina

Published
2024
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2. Dietary protein and blood pressure: an umbrella review of systematic reviews and evaluation of the evidence

Author

Boeing, Heiner, Amini, Anna M., Haardt, Julia, Schmidt, Annemarie, Bischoff-Ferrari, Heike A., Buyken, Anette E., Egert, Sarah, Ellinger, Sabine, Kroke, Anja, Lorkowski, Stefan, Louis, Sandrine, Nimptsch, Katharina, Schulze, Matthias B., Schutkowski, Alexandra, Schwingshackl, Lukas, Siener, Roswitha, Zittermann, Armin, Watzl, Bernhard, and Stangl, Gabriele I.

Published
2024
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3. Protein intake and body weight, fat mass and waist circumference: an umbrella review of systematic reviews for the evidence-based guideline on protein intake of the German Nutrition Society

Author

Ellinger, Sabine, Amini, Anna M., Haardt, Julia, Lehmann, Andreas, Schmidt, Annemarie, Bischoff-Ferrari, Heike A., Buyken, Anette E., Kroke, Anja, Kühn, Tilman, Louis, Sandrine, Lorkowski, Stefan, Nimptsch, Katharina, Schulze, Matthias B., Schwingshackl, Lukas, Siener, Roswitha, Stangl, Gabriele I., Volkert, Dorothee, Zittermann, Armin, Watzl, Bernhard, and Egert, Sarah

Published
2024
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4. Protein intake and type 2 diabetes mellitus: an umbrella review of systematic reviews for the evidence-based guideline for protein intake of the German Nutrition Society

Author

Schulze, Matthias B., Haardt, Julia, Amini, Anna M., Kalotai, Nicole, Lehmann, Andreas, Schmidt, Annemarie, Buyken, Anette E., Egert, Sarah, Ellinger, Sabine, Kroke, Anja, Kühn, Tilman, Louis, Sandrine, Nimptsch, Katharina, Schwingshackl, Lukas, Siener, Roswitha, Zittermann, Armin, Watzl, Bernhard, and Lorkowski, Stefan

Published
2024
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6. Protein intake and risk of urolithiasis and kidney diseases: an umbrella review of systematic reviews for the evidence-based guideline of the German Nutrition Society

Author

Remer, Thomas, Kalotai, Nicole, Amini, Anna M., Lehmann, Andreas, Schmidt, Annemarie, Bischoff-Ferrari, Heike A., Egert, Sarah, Ellinger, Sabine, Kroke, Anja, Kühn, Tilman, Lorkowski, Stefan, Nimptsch, Katharina, Schwingshackl, Lukas, Zittermann, Armin, Watzl, Bernhard, and Siener, Roswitha

Published
2023
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7. Protein intake and bone health: an umbrella review of systematic reviews for the evidence-based guideline of the German Nutrition Society

Author

Zittermann, Armin, Schmidt, Annemarie, Haardt, Julia, Kalotai, Nicole, Lehmann, Andreas, Egert, Sarah, Ellinger, Sabine, Kroke, Anja, Lorkowski, Stefan, Louis, Sandrine, Schulze, Matthias B., Schwingshackl, Lukas, Siener, Roswitha, Stangl, Gabriele I., Volkert, Dorothee, Watzl, Bernhard, and Bischoff-Ferrari, Heike A.

Published
2023
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10. Iron Deficiency and Incident Infections among Community-Dwelling Adults Age 70 Years and Older: Results from the DO-HEALTH Study

Author

Lanz, P., Wieczorek, M., Sadlon, A., de Godoi Rezende Costa Molino, C., Abderhalden, L. A., Schaer, D. J., Spahn, D. R., Freystätter, G., Orav, E. J., Egli, A., Bischoff-Ferrari, Heike A., Rival, Sandrine, Guyonnet, Sophie, Biver, Emmanuel, Merminod, Fanny, Bridenbaugh, Stephanie, Suhm, Norbert, Duarte, Cátia C. M., Pinto, Ana Filipa, Felsenberg, Dieter, Börst, Hendrikje, Spicher, Anna, Felson, David T., Mccloskey, Eugene V., Johansson, Elena, Watzl, Bernhard, Gomez, Manuel Rodriguez, Tsourdi, Elena, Rauner, Martina, Halbout, Philippe, Ferrari, Stephen M., Gut, Benno, Ba, Marième, Schegg, Jonas Wittwer, Etheve, Stéphane, Eggersdorfer, Manfred, Delannoy, Carla Sofia, Reuschling, Monika, Staehelin, Hannes B., Walter, Paul W., Dick, Walter, Fried, Michael, von Eckardstein, Arnold, Simmen, Hans-Peter, Langhans, Wolfgang, Zinkernagel, Annelies, Mueller, Nicolas, Distler, Oliver, Graetz, Klaus, Nitschke, Ina, Dietrich, Thomas, Baer, Walter, Landau, Klara, Ruschitzka, Frank, Manz, Markus, and Burckhardt, Peter

Published
2022
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11. Dietary protein intake and health-related outcomes: a methodological protocol for the evidence evaluation and the outline of an evidence to decision framework underlying the evidence-based guideline of the German Nutrition Society

Author

Kroke, Anja, Schmidt, Annemarie, Amini, Anna M., Kalotai, Nicole, Lehmann, Andreas, Haardt, Julia, Bauer, Jürgen M., Bischoff-Ferrari, Heike A., Boeing, Heiner, Egert, Sarah, Ellinger, Sabine, Kühn, Tilman, Louis, Sandrine, Lorkowski, Stefan, Nimptsch, Katharina, Remer, Thomas, Schulze, Matthias B., Siener, Roswitha, Stangl, Gabriele I., Volkert, Dorothee, Zittermann, Armin, Buyken, Anette E., Watzl, Bernhard, and Schwingshackl, Lukas

Published
2022
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18. Perspective: A Conceptual Framework for Adaptive Personalized Nutrition Advice Systems

Author

Renner, Britta, primary, Buyken, Anette E., additional, Gedrich, Kurt, additional, Lorkowski, Stefan, additional, Watzl, Bernhard, additional, Linseisen, Jakob, additional, Daniel, Hannelore, additional, Conrad, Johanna, additional, Ferrario, Paola G., additional, Holzapfel, Christina, additional, Leitzmann, Michael, additional, Richter, Margrit, additional, Simon, Marie-Christine, additional, Sina, Christian, additional, and Wirsam, Jan, additional

Published
2023
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20. Protein intake and bone health: an umbrella review of systematic reviews for the evidence-based guideline of the German Nutrition Society

Author

Zittermann, Armin; https://orcid.org/0000-0001-6085-6554, Schmidt, Annemarie; https://orcid.org/0000-0003-4607-4534, Haardt, Julia, Kalotai, Nicole, Lehmann, Andreas, Egert, Sarah, Ellinger, Sabine; https://orcid.org/0000-0002-9988-9406, Kroke, Anja; https://orcid.org/0000-0002-0253-1644, Lorkowski, Stefan; https://orcid.org/0000-0002-9649-840X, Louis, Sandrine, Schulze, Matthias B; https://orcid.org/0000-0002-0830-5277, Schwingshackl, Lukas; https://orcid.org/0000-0003-3407-7594, Siener, Roswitha, Stangl, Gabriele I; https://orcid.org/0000-0001-8073-524X, Volkert, Dorothee, Watzl, Bernhard; https://orcid.org/0000-0003-0762-7423, Bischoff Ferrari, Heike A; https://orcid.org/0000-0002-4554-658X, German Nutrition Society, Zittermann, Armin; https://orcid.org/0000-0001-6085-6554, Schmidt, Annemarie; https://orcid.org/0000-0003-4607-4534, Haardt, Julia, Kalotai, Nicole, Lehmann, Andreas, Egert, Sarah, Ellinger, Sabine; https://orcid.org/0000-0002-9988-9406, Kroke, Anja; https://orcid.org/0000-0002-0253-1644, Lorkowski, Stefan; https://orcid.org/0000-0002-9649-840X, Louis, Sandrine, Schulze, Matthias B; https://orcid.org/0000-0002-0830-5277, Schwingshackl, Lukas; https://orcid.org/0000-0003-3407-7594, Siener, Roswitha, Stangl, Gabriele I; https://orcid.org/0000-0001-8073-524X, Volkert, Dorothee, Watzl, Bernhard; https://orcid.org/0000-0003-0762-7423, Bischoff Ferrari, Heike A; https://orcid.org/0000-0002-4554-658X, and German Nutrition Society

Abstract

This umbrella review aimed at assessing whether a protein intake exceeding the current recommendation for younger (0.8 g/kg body weight [BW]/day) and older (1.0 g/kg BW/day) adults affects bone mineral density and fracture risk. Moreover, the effect of animal or plant protein was evaluated. A systematic literature search was conducted in PubMed, Embase, and Cochrane Database of Systematic Reviews for systematic reviews (SRs) with or without meta-analysis of prospective studies published between 11/2008 and 08/2021. Methodological quality, outcome-specific certainty of evidence, and overall certainty of evidence of the retrieved SRs were assessed using established tools and predefined criteria. Eleven SRs of randomized controlled trials (RCTs) and/or cohort studies were included. In SRs of cohort studies and RCTs, protein intake/kg BW/day ranged between 0.21-0.95 g (low intake) and > 1.24 g (high intake), respectively, and between 0.67-1.1 g (control groups) and 1.01-1.69 g (intervention groups), respectively. The vast majority of outcome-specific certainty of evidence was rated "low" or "very low." The overall certainty of evidence for an association (cohort studies) or effect (RCTs) of total, animal or plant protein intake on each of the investigated outcomes was rated "insufficient," with the exception of possible evidence for a reduced hip fracture risk by high vs. low protein intake. Since protein intakes in low/control and high/intervention groups were very heterogeneous and with low certainty of evidence, it remains unclear whether a dose above the current recommendation or type of protein intake (animal or plant protein) affects bone health overall. However, there is possible evidence for reduced hip fracture risk with high versus low protein intake.

Published
2023

22. Perspective: a conceptual framework for adaptive personalized nutrition advice systems (APNASs)

Author

Renner, Britta, Buyken, Anette E., Gedrich, Kurt, Lorkowski, Stefan, Watzl, Bernhard, Linseisen, Jakob, Daniel, Hannelore, Conrad, Johanna, Ferrario, Paola G., Holzapfel, Christina, Leitzmann, Michael, Richter, Margrit, Simon, Marie-Christine, Sina, Christian, and Wirsam, Jan

Subjects
ddc:610
Abstract

Nearly all approaches to personalized nutrition (PN) use information such as the gene variants of individuals to deliver advice that is more beneficial than a generic one-size-fits-all recommendation. Despite great enthusiasm and the increased availability of commercial services, thus far, scientific studies have only revealed small to negligible effects on the efficacy and effectiveness of personalized dietary recommendations, even when using genetic or other individual information. In addition, from a public health perspective, scholars are critical of PN because it primarily targets socially privileged groups rather than the general population, thereby potentially widening health inequality. Therefore, in this perspective, we propose to extend current PN approaches by creating adaptive personalized nutrition advice systems (APNASs) that are tailored to the type and timing of personalized advice for individual needs, capacities, and receptivity in real-life food environments. These systems encompass a broadening of current PN goals (i.e., what should be achieved) to incorporate individual goal preferences beyond currently advocated biomedical targets (e.g., making sustainable food choices). Moreover, they cover the personalization processes of behavior change by providing in situ, just-in-time information in real-life environments (how and when to change), which accounts for individual capacities and constraints (e.g., economic resources). Finally, they are concerned with a participatory dialogue between individuals and experts (e.g., actual or virtual dieticians, nutritionists, and advisors), when setting goals and deriving measures of adaption. Within this framework, emerging digital nutrition ecosystems enable continuous, real-time monitoring, advice, and support in food environments from exposure to consumption. We present this vision of a novel PN framework along with scenarios and arguments that describe its potential to efficiently address individual and population needs and target groups that would benefit most from its implementation.

Published
2023

24. Assessment of Energy and Nutrient Intake and the Intestinal Microbiome (ErNst study): Protocol and Methods of a Cross-sectional Human Observational Study (Preprint)

Author

Dötsch, Andreas, primary, Merz, Benedikt, additional, Louis, Sandrine, additional, Krems, Carolin, additional, Herrmann, Maria, additional, Dörr, Claudia, additional, Watzl, Bernhard, additional, Bub, Achim, additional, Straßburg, Andrea, additional, and Engelbert, Ann Katrin, additional

Published
2022
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30. Dietary protein intake and health-related outcomes: a methodological protocol for the evidence evaluation and the outline of an evidence to decision framework underlying the evidence-based guideline of the German Nutrition Society

Author

Kroke, Anja; https://orcid.org/0000-0002-0253-1644, Schmidt, Annemarie; https://orcid.org/0000-0003-4607-4534, Amini, Anna M; https://orcid.org/0000-0003-4288-1769, Kalotai, Nicole, Lehmann, Andreas, Haardt, Julia, Bauer, Jürgen M, Bischoff-Ferrari, Heike A, Boeing, Heiner, Egert, Sarah, Ellinger, Sabine; https://orcid.org/0000-0002-9988-9406, Kühn, Tilman, Louis, Sandrine, Lorkowski, Stefan; https://orcid.org/0000-0002-9649-840X, Nimptsch, Katharina, Remer, Thomas, Schulze, Matthias B; https://orcid.org/0000-0002-0830-5277, Siener, Roswitha, Stangl, Gabriele I; https://orcid.org/0000-0001-8073-524X, Volkert, Dorothee, Zittermann, Armin; https://orcid.org/0000-0001-6085-6554, Buyken, Anette E, Watzl, Bernhard; https://orcid.org/0000-0003-0762-7423, Schwingshackl, Lukas; https://orcid.org/0000-0003-3407-7594, Kroke, Anja; https://orcid.org/0000-0002-0253-1644, Schmidt, Annemarie; https://orcid.org/0000-0003-4607-4534, Amini, Anna M; https://orcid.org/0000-0003-4288-1769, Kalotai, Nicole, Lehmann, Andreas, Haardt, Julia, Bauer, Jürgen M, Bischoff-Ferrari, Heike A, Boeing, Heiner, Egert, Sarah, Ellinger, Sabine; https://orcid.org/0000-0002-9988-9406, Kühn, Tilman, Louis, Sandrine, Lorkowski, Stefan; https://orcid.org/0000-0002-9649-840X, Nimptsch, Katharina, Remer, Thomas, Schulze, Matthias B; https://orcid.org/0000-0002-0830-5277, Siener, Roswitha, Stangl, Gabriele I; https://orcid.org/0000-0001-8073-524X, Volkert, Dorothee, Zittermann, Armin; https://orcid.org/0000-0001-6085-6554, Buyken, Anette E, Watzl, Bernhard; https://orcid.org/0000-0003-0762-7423, and Schwingshackl, Lukas; https://orcid.org/0000-0003-3407-7594

Abstract

Purpose: The present work aimed to delineate (i) a revised protocol according to recent methodological developments in evidence generation, to (ii) describe its interpretation, the assessment of the overall certainty of evidence and to (iii) outline an Evidence to Decision framework for deriving an evidence-based guideline on quantitative and qualitative aspects of dietary protein intake. Methods: A methodological protocol to systematically investigate the association between dietary protein intake and several health outcomes and for deriving dietary protein intake recommendations for the primary prevention of various non-communicable diseases in the general adult population was developed. Results: The developed methodological protocol relies on umbrella reviews including systematic reviews with or without meta-analyses. Systematic literature searches in three databases will be performed for each health-related outcome. The methodological quality of all selected systematic reviews will be evaluated using a modified version of AMSTAR 2, and the outcome-specific certainty of evidence for systematic reviews with or without meta-analysis will be assessed with NutriGrade. The general outline of the Evidence to Decision framework foresees that recommendations in the derived guideline will be given based on the overall certainty of evidence as well as on additional criteria such as sustainability. Conclusion: The methodological protocol permits a systematic evaluation of published systematic reviews on dietary protein intake and its association with selected health-related outcomes. An Evidence to Decision framework will be the basis for the overall conclusions and the resulting recommendations for dietary protein intake. Keywords: Evidence-based guideline; Method; Nutrition-related diseases; Prevention; Protein intake

Published
2022

31. Guidelines on the management of IgE-mediated food allergies: S2k-Guidelines of the German Society for Allergology and Clinical Immunology (DGAKI) in collaboration with the German Medical Association of Allergologists (AeDA), the German Professional Association of Pediatricians (BVKJ), the German Allergy and Asthma Association (DAAB), German Dermatological Society (DDG), the German Society for Nutrition (DGE), the German Society for Gastroenterology, Digestive and Metabolic Diseases (DGVS), the German Society for Oto-Rhino-Laryngology, Head and Neck Surgery, the German Society for Pediatric and Adolescent Medicine (DGKJ), the German Society for Pediatric Allergology and Environmental Medicine (GPA), the German Society for Pneumology (DGP), the German Society for Pediatric Gastroenterology and Nutrition (GPGE), German Contact Allergy Group (DKG), the Austrian Society for Allergology and Immunology (Æ-GAI), German Professional Association of Nutritional Sciences (VDOE) and the Association of the Scientific Medical Societies Germany (AWMF)

Author

Worm, Margitta, Reese, Imke, Ballmer-Weber, Barbara, Beyer, Kirsten, Bischoff, Stephan C., Classen, Martin, Fischer, Peter J., Fuchs, Thomas, Huttegger, Isidor, Jappe, Uta, Klimek, Ludger, Koletzko, Berthold, Lange, Lars, Lepp, Ute, Mahler, Vera, Niggemann, Bodo, Rabe, Ute, Raithel, Martin, Saloga, Joachim, Schäfer, Christiane, Schnadt, Sabine, Schreiber, Jens, Szépfalusi, Zsolt, Treudler, Regina, Wagenmann, Martin, Watzl, Bernhard, Werfel, Thomas, Zuberbier, Torsten, and Kleine-Tebbe, Jörg

Published
2015
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34. Human health risk–benefit assessment of fish and other seafood: a scoping review.

Author

Thomsen, Sofie Theresa, Assunção, Ricardo, Afonso, Cláudia, Boué, Géraldine, Cardoso, Carlos, Cubadda, Francesco, Garre, Alberto, Kruisselbrink, Johannes W., Mantovani, Alberto, Pitter, János G., Poulsen, Morten, Verhagen, Hans, Ververis, Ermolaos, Voet, Hilko van der, Watzl, Bernhard, and Pires, Sara M.

Abstract

Fish and other seafood are important sources of nutrients, but they are also sources of chemical contaminants that may cause adverse health effects. This article aimed to identify existing risk–benefit assessments (RBA) of fish, shellfish, and other seafood, compare methodologies, discuss differences and commonalities in findings, and identify limitations and ways forward for future studies. We conducted a scoping review of the scientific literature of studies in all languages published from 2000 through April 2019. We identified 106 RBA of fish and other seafood across Europe, Asia, North America, Africa, and at the global level. Studies were heterogeneous in terms of types of fish and other seafood considered, beneficial and adverse compounds assessed, and overall methodology. Collected data showed that a diet consisting of a variety of lean and fatty fish and other seafood is recommended for the overall population and that women of childbearing age and children should limit the consumption of fish and other seafood types that have a high likelihood of contamination. Our review emphasizes the need for evidence-based, up-to-date, and harmonized approaches in RBA in general. [ABSTRACT FROM AUTHOR]

Published
2022
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39. DGE-Positionspapier zur nachhaltigeren Ernährung

Author

Renner, Britta, Arens-Azevêdo, Ulrike, Watzl, Bernhard, Richter, Margrit, Virmani, Kiran, and Linseisen, Jakob

Subjects
ddc:150, GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries)
Abstract

published

Published
2021

40. What is the promise of personalised nutrition?

Author

Ferrario, Paola G, Watzl, Bernhard, Møller, Grith, Ritz, Christian, Ferrario, Paola G, Watzl, Bernhard, Møller, Grith, and Ritz, Christian

Abstract

Personalised nutrition (PN) is an emerging field that bears great promise. Several definitions of PN have been proposed and different modelling approaches have been used to claim PN effects. We tentatively propose to group these approaches into two categories, which we term outcome-based and population reference approaches, respectively. Understanding the fundamental differences between these two types of modelling approaches may allow a more realistic appreciation of what to expect from PN interventions presently and may be helpful for designing and planning future studies investigating PN interventions.

Published
2021

41. Integration of various dimensions in food-based dietary guidelines via mathematical approaches:Report of a DGE/FENS Workshop in Bonn, Germany, 23-24 September 2019

Author

Schäfer, Anne Carolin, Schmidt, Annemarie, Bechthold, Angela, Boeing, Heiner, Watzl, Bernhard, Darmon, Nicole, Devleesschauwer, Brecht, Heckelei, Thomas, Pires, Sara Monteiro, Nadaud, Perrine, van Dooren, Corné, Vieux, Florent, Schäfer, Anne Carolin, Schmidt, Annemarie, Bechthold, Angela, Boeing, Heiner, Watzl, Bernhard, Darmon, Nicole, Devleesschauwer, Brecht, Heckelei, Thomas, Pires, Sara Monteiro, Nadaud, Perrine, van Dooren, Corné, and Vieux, Florent

Abstract

In the past, food-based dietary guidelines (FBDGs) were derived nearly exclusively by using systematic reviews on diet-health-relationships and translating dietary reference values for nutrient intake into foods. This approach neglects many other implications that dietary recommendations have on society, the economy and environment. In view of pressing challenges, such as climate change and the rising burden of diet-related diseases, the simultaneous integration of evidence-based findings from different dimensions into FBDGs is required. Consequently, mathematical methods and data processing are evolving as powerful tools in nutritional sciences. The possibilities and reasons for the derivation of FBDGs via mathematical approaches were the subject of a joint workshop hosted by the German Nutrition Society (DGE) and the Federation of European Nutrition Societies (FENS) in September 2019 in Bonn, Germany. European scientists were invited to discuss and exchange on the topics of mathematical optimisation for the development of FBDGs and different approaches to integrate various dimensions into FBDGs. We concluded that mathematical optimisation is a suitable tool to formulate FBDGs finding trade-offs between conflicting goals and taking several dimensions into account. We identified a lack of evidence for the extent to which constraints and weights for different dimensions are set and the challenge to compile diverse data that suit the demands of optimisation models. We also found that individualisation via mathematical optimisation is one perspective of FBDGs to increase consumer acceptance, but the application of mathematical optimisation for population-based and individual FBDGs requires more experience and evaluation for further improvements.

Published
2021

46. Guidance for substantiating the evidence for beneficial effects of probiotics: impact of probiotics on digestive system metabolism

Author

Rabot, Svlvie, Rafter, Joseph, Rijkers, Ger T., Watzl, Bernhard, and Antoines, Jean-Michel

Subjects
Probiotics -- Health aspects, Metabolic diseases -- Care and treatment, Food/cooking/nutrition
Abstract

Probiotic bacteria have been studied for their potential impact on the metabolism of dietary components in the small intestine lumen including lactose digestion, metabolism of lipids such as cholesterol, and oxalate metabolism. In the large intestine, they contribute to the metabolism of otherwise indigestible dietary carbohydrates (e.g., prebiotics) and have a favorable effect on colonic protein and ammonia metabolism, although their effect on the digestive fate of phytochemicals and xenobiotics is still uncertain. Probiotics also influence metabolism in the host tissues, in particular the gastrointestinal mucosa and the liver. Underlying mechanisms include supply of additional enzymatic activities in the gut lumen and alterations of the composition or metabolic pattern of the gut resident microbiota. For future studies, selection of probiotic strains should include assessment of their metabolic activities, and the outcome of the intervention studies should also take into account the composition of the probiotic matrix and the background diet of the target population. New technologies such as metabolomics hold great promise for assessment of probiotics functionality. doi: 10.3945/jn.109.113738.

Published
2010

47. Guidance for substantiating the evidence for beneficial effects of probiotics: current status and recommendations for future research

Author

Rijkers, Ger T., Bengmark, Stig, Enck, Paul, Haller, Dirk, Herz, Udo, Kalliomaki, Marko, Kudo, Satoshi, Lenoir-Wijnkoop, Irene, Mercenier, Annick, Myllyluoma, Eveliina, Rabot, Sylvie, Rafter, Joseph, Szajewska, Hania, Watzl, Bernhard, Wells, Jerry, Wolvers, Danielle, and Antoine, Jean-Michel

Subjects
Probiotics -- Dosage and administration, Probiotics -- Health aspects, Gastrointestinal system -- Health aspects, Food/cooking/nutrition
Abstract

Probiotic bacteria are live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. There is a growing interest in probiotics within the scientific community, with consumers, and in the food industry. The interactions between the gut and intestinal microbiota and between resident and transient microbiota define a new arena in physiology, an understanding of which would shed light on the 'cross-talk' between humans and microbes. The different beneficial effects of specific probiotic strains may be translated into different health claims. However, there is a need for comprehensive and harmonized guidelines on the assessment of the characteristics and efficacy of probiotics and of foods containing them. An international expert group of ILSI has evaluated the published evidence of the functionality of different probiotics in 4 areas of (human) application: 1) metabolism, 2) chronic intestinal inflammatory and functional disorders, 3) infections, and 4) allergy. Based on the existing evidence, concrete examples of demonstration of benefits and gaps are listed, and guidelines and recommendations are defined that should help design the next generation of probiotic studies. doi: 10.3945/jn.109.113779.

Published
2010

48. Human health risk–benefit assessment of fish and other seafood: a scoping review

Author

Thomsen, Sofie Theresa, primary, Assunção, Ricardo, additional, Afonso, Cláudia, additional, Boué, Géraldine, additional, Cardoso, Carlos, additional, Cubadda, Francesco, additional, Garre, Alberto, additional, Kruisselbrink, Johannes W., additional, Mantovani, Alberto, additional, Pitter, János G., additional, Poulsen, Morten, additional, Verhagen, Hans, additional, Ververis, Ermolaos, additional, Voet, Hilko van der, additional, Watzl, Bernhard, additional, and Pires, Sara M., additional

Published
2021
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50. Effect of Vitamin D Supplementation, Omega-3 Fatty Acid Supplementation, or a Strength-Training Exercise Program on Clinical Outcomes in Older Adults

Author

Bischoff-Ferrari, Heike A, Vellas, Bruno, Rizzoli, René, Kressig, Reto W, da Silva, José A P, Blauth, Michael, Felson, David T, McCloskey, Eugene V, Watzl, Bernhard, Hofbauer, Lorenz C, Felsenberg, Dieter, Willett, Walter C, Dawson-Hughes, Bess, Manson, JoAnn E, Siebert, Uwe, Theiler, Robert, Staehelin, Hannes B, de Godoi Rezende Costa Molino, Caroline, Chocano-Bedoya, Patricia O, Abderhalden, Lauren A, Egli, Andreas, Kanis, John A, Orav, Endel J, and University of Zurich

Subjects
11221 Clinic for Geriatric Medicine, 610 Medicine & health, 2700 General Medicine, General Medicine
Published
2020

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