1. Factors Associated With Severity of COVID-19 Disease in a Multicenter Cohort of People With HIV in the United States, March–December 2020
- Author
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Shapiro, Adrienne E, Ignacio, Rachel A Bender, Whitney, Bridget M, Delaney, Joseph A, Nance, Robin M, Bamford, Laura, Wooten, Darcy, Keruly, Jeanne C, Burkholder, Greer, Napravnik, Sonia, Mayer, Kenneth H, Webel, Allison R, Kim, H Nina, Van Rompaey, Stephen E, Christopoulos, Katerina, Jacobson, Jeffrey, Karris, Maile, Smith, Davey, Johnson, Mallory O, Willig, Amanda, Eron, Joseph J, Hunt, Peter, Moore, Richard D, Saag, Michael S, Mathews, W Christopher, Crane, Heidi M, Cachay, Edward R, Kitahata, Mari M, and Systems, for the CFAR Network of Integrated Clinical
- Subjects
Biomedical and Clinical Sciences ,Clinical Sciences ,Health Sciences ,Lung ,Prevention ,Coronaviruses ,Sexually Transmitted Infections ,Infectious Diseases ,Emerging Infectious Diseases ,Clinical Research ,HIV/AIDS ,6.1 Pharmaceuticals ,Evaluation of treatments and therapeutic interventions ,Good Health and Well Being ,CD4 Lymphocyte Count ,COVID-19 ,COVID-19 Vaccines ,HIV Infections ,Humans ,Renal Insufficiency ,Chronic ,United States ,HIV ,CD4 count ,structural determinants of health ,immunosuppression ,CFAR Network of Integrated Clinical Systems ,Public Health and Health Services ,Virology ,Clinical sciences ,Epidemiology ,Public health - Abstract
BackgroundUnderstanding the spectrum of COVID-19 in people with HIV (PWH) is critical to provide clinical guidance and risk reduction strategies.SettingCenters for AIDS Research Network of Integrated Clinic System, a US multisite clinical cohort of PWH in care.MethodsWe identified COVID-19 cases and severity (hospitalization, intensive care, and death) in a large, diverse HIV cohort during March 1, 2020-December 31, 2020. We determined predictors and relative risks of hospitalization among PWH with COVID-19, adjusted for disease risk scores.ResultsOf 16,056 PWH in care, 649 were diagnosed with COVID-19 between March and December 2020. Case fatality was 2%; 106 (16.3%) were hospitalized, and 12 died. PWH with current CD4 count
- Published
- 2022