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Electrical stimulation (ES) is widely used in physiological and medical sciences, while its application to treat inflammatory skin diseases (ISDs) remains a challenge owing to their natural pathological cuticle barrier and lack of an effective combination with chemotherapy to achieve specific immunomodulation. Here, a wearable, battery‐free, multi‐component drug‐loaded electronic microneedle (mD‐eMN) system is developed by integrating remodeled metal microneedles loaded with multi‐component chemical drugs and flexible triboelectric nanogenerators (TENGs). The system can rapidly release drugs into the site of ISDs and then realize an efficient penetration into cell body and specific immunomodulation under the synergism of pulsed electrons originating from the TENG. Also, the pulsed electrons can promote skin tissue homeostasis reconstruction to alleviate the inflammatory process of ISDs. Sufficient evidence shows that a significant skin inflammation regression of psoriasis (a typical ISDs model) is achieved using the mD‐eMN system compared to traditional ES or chemotherapy alone. This innovative wearable mD‐eMN system provides an effective flexible electronic and chemical drug joint technological platform for the treatment of ISDs, which is not only suitable for the treatment of psoriasis in this study but also maybe for other ISDs such as diabetic ulcers and skin tumors. [ABSTRACT FROM AUTHOR]

Peripheral nerve injury (PNI) remains an intractable challenge in regenerative medicine. Recently, physical cue‐based strategies (e.g., electrical neurostimulation, acoustic radiation, electromagnetic bioregulation, as well as directional fiber guiding, etc.) have drawn increasing attention not only as a stimulator for cell functions modulation and fate determination, but also as a morphology‐index for modulating cell phenotype, proliferation, and differentiation, especially for nerve cells. More importantly, the advanced percutaneous power transmission technology, self‐power nanotechnology that leverages piezoelectrical/triboelectricity materials, and focused ultrasound and pulsed electromagnetic field technology exhibit the appealing practice potential for achieving low‐invasive, wireless, and battery‐free neuromodulation. In this review, recent advances of physical cue‐based strategies including electrical, acoustic, magnetic, and morphology for PNI are systematically overviewed, and the open challenges for realizing scalable clinical/commercial transformation and future perspectives of these strategies for PNI are concluded. [ABSTRACT FROM AUTHOR]

Surface reconstructed SrTiO3 nanocrystals were synthesized by a thermal treatment process in presence of NaBH4 and SrTiO3 nanocrystals. The surface reconstruction of SrTiO3 nanocrystals is attributed to the introduction of surface oxygen vacancies or Ti sites (such as Ti3+ and Ti2+) during the hydrogenation treatment process. The light absorption and the charge transfer ability of SrTiO3 nanocrystals are simultaneously enhanced due to surface oxygen vacancies or Ti sites (such as Ti3+ and Ti2+), which are beneficial to photocatalytic water splitting. Meanwhile, these defects also change the redox potential of the photocatalysts. Since there existed a synergistic effect between the three, the ratio of hydrogen to oxygen production was also regulated. [ABSTRACT FROM AUTHOR]