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2. Long-term air pollution exposure and malignant intracranial tumours of the central nervous system: a pooled analysis of six European cohorts

Author

Hvidtfeldt, Ulla Arthur, Chen, Jie, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K. E., Nagel, Gabriele, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, So, Rina, Stafoggia, Massimo, Tjønneland, Anne, Weinmayr, Gudrun, Wolf, Kathrin, Zhang, Jiawei, Zitt, Emanuel, Brunekreef, Bert, Hoek, Gerard, and Raaschou-Nielsen, Ole

Published
2023
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3. Long-term exposure to air pollution and chronic kidney disease-associated mortality–Results from the pooled cohort of the European multicentre ELAPSE-study

Author

Kadelbach, Pauline, Weinmayr, Gudrun, Chen, Jie, Jaensch, Andrea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Cesaroni, Giulia, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Ljungman, Petter, Magnusson, Patrik K.E., Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Peters, Annette, Wolf, Kathrin, Raaschou-Nielsen, Ole, Brunekreef, Bert, Hoek, Gerard, Zitt, Emanuel, and Nagel, Gabriele

Published
2024
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4. Long-term exposure to ambient air pollution and risk of leukemia and lymphoma in a pooled European cohort

Author

Taj, Tahir, Chen, Jie, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Poulsen, Aslak Harbo, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Zitt, Emanuel, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Jørgensen, Jeanette T., Katsouyanni, Klea, Ketzel, Matthias, Lager, Anton, Leander, Karin, Liu, Shuo, Ljungman, Petter, Severi, Gianluca, Besson, Caroline, Magnusson, Patrik K.E., Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Rizzuto, Debora, Samoli, Evangelia, Sørensen, Mette, Stafoggia, Massimo, Tjønneland, Anne, Weinmayr, Gudrun, Wolf, Kathrin, Brunekreef, Bert, Hoek, Gerard, and Raaschou-Nielsen, Ole

Published
2024
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5. Multiple myeloma risk in relation to long-term air pollution exposure - A pooled analysis of four European cohorts

Author

Hvidtfeldt, Ulla Arthur, Chen, Jie, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Forastiere, Francesco, Brynedal, Boel, Hertel, Ole, Hoffmann, Barbara, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K.E., Nagel, Gabriele, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, So, Rina, Stafoggia, Massimo, Tjønneland, Anne, Weinmayr, Gudrun, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Hoek, Gerard, and Raaschou-Nielsen, Ole

Published
2023
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7. Long-term air pollution exposure and Parkinson’s disease mortality in a large pooled European cohort: An ELAPSE study

Author

Cole-Hunter, Thomas, Zhang, Jiawei, So, Rina, Samoli, Evangelia, Liu, Shuo, Chen, Jie, Strak, Maciej, Wolf, Kathrin, Weinmayr, Gudrun, Rodopolou, Sophia, Remfry, Elizabeth, de Hoogh, Kees, Bellander, Tom, Brandt, Jørgen, Concin, Hans, Zitt, Emanuel, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hoffmann, Barbara, Hvidtfeldt, Ulla A., Jöckel, Karl-Heinz, Mortensen, Laust H., Ketzel, Matthias, Yacamán Méndez, Diego, Leander, Karin, Ljungman, Petter, Faure, Elodie, Lee, Pei-Chen, Elbaz, Alexis, Magnusson, Patrik K.E., Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Rizzuto, Debora, Vermeulen, Roel C.H., Schramm, Sara, Stafoggia, Massimo, Katsouyanni, Klea, Brunekreef, Bert, Hoek, Gerard, Lim, Youn-Hee, and Andersen, Zorana J.

Published
2023
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8. Long-term exposure to air pollution and mortality from dementia, psychiatric disorders, and suicide in a large pooled European cohort: ELAPSE study

Author

Andersen, Zorana J., Zhang, Jiawei, Jørgensen, Jeanette T., Samoli, Evangelia, Liu, Shuo, Chen, Jie, Strak, Maciej, Wolf, Kathrin, Weinmayr, Gudrun, Rodopolou, Sophia, Remfry, Elizabeth, de Hoogh, Kees, Bellander, Tom, Brandt, Jørgen, Concin, Hans, Zitt, Emanuel, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hoffmann, Barbara, Hvidtfeldt, Ulla A., Monique Verschuren, W.M., Jöckel, Karl-Heinz, So, Rina, Cole-Hunter, Tom, Mehta, Amar J., Mortensen, Laust H., Ketzel, Matthias, Lager, Anton, Leander, Karin, Ljungman, Petter, Severi, Gianluca, Boutron-Ruault, Marie-Christine, Magnusson, Patrik K.E., Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Rizzuto, Debora, van der Schouw, Yvonne T., Schramm, Sara, Stafoggia, Massimo, Katsouyanni, Klea, Brunekreef, Bert, Hoek, Gerard, and Lim, Youn-Hee

Published
2022
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9. Long term exposure to air pollution and kidney parenchyma cancer – Effects of low-level air pollution: a Study in Europe (ELAPSE)

Author

Hvidtfeldt, Ulla Arthur, Taj, Tahir, Chen, Jie, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Jørgensen, Jeanette T., Katsouyanni, Klea, Ketzel, Matthias, Lager, Anton, Leander, Karin, Ljungman, Petter, Magnusson, Patrik K.E., Nagel, Gabriele, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, So, Rina, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Weinmayr, Gudrun, Wolf, Kathrin, Zhang, Jiawei, Zitt, Emanuel, Brunekreef, Bert, Hoek, Gerard, and Raaschou-Nielsen, Ole

Published
2022
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10. Long-term exposure to ambient air pollution and bladder cancer incidence in a pooled European cohort: the ELAPSE project

Author

Chen, Jie, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Taj, Tahir, Poulsen, Aslak Harbo, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Zitt, Emanuel, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Verschuren, W. M. Monique, Jørgensen, Jeanette T., Katsouyanni, Klea, Ketzel, Matthias, Lager, Anton, Leander, Karin, Liu, Shuo, Ljungman, Petter, Severi, Gianluca, Boutron-Ruault, Marie-Christine, Magnusson, Patrik K. E., Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Rizzuto, Debora, van der Schouw, Yvonne T., Samoli, Evangelia, Sørensen, Mette, Stafoggia, Massimo, Tjønneland, Anne, Weinmayr, Gudrun, Wolf, Kathrin, Brunekreef, Bert, Raaschou-Nielsen, Ole, and Hoek, Gerard

Published
2022
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11. Exposure to surrounding greenness and natural-cause and cause-specific mortality in the ELAPSE pooled cohort

Author

Bereziartua, Ainhoa, Chen, Jie, de Hoogh, Kees, Rodopoulou, Sophia, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Arthur Hvidtfeldt, Ulla, Verschuren, W.M.Monique, Jöckel, Karl-Heinz, Jørgensen, Jeanette T, Katsouyanni, Klea, Ketzel, Matthias, Hjertager Krog, Norun, Brynedal, Boel, Leander, Karin, Liu, Shuo, Ljungman, Petter, Faure, Elodie, Magnusson, Patrik K.E., Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Raaschou-Nielsen, Ole, Renzi, Matteo, Rizzuto, Debora, Samoli, Evangelia, van der Schouw, Yvonne T., Schramm, Sara, Severi, Gianluca, Stafoggia, Massimo, Strak, Maciej, Sørensen, Mette, Tjønneland, Anne, Weinmayr, Gudrun, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, and Hoek, Gerard

Published
2022
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12. Global estimates of mortality associated with long-term exposure to outdoor fine particulate matter.

Author

Burnett, Richard, Chen, Hong, Szyszkowicz, Mieczysław, Fann, Neal, Hubbell, Bryan, Pope, C Arden, Apte, Joshua S, Brauer, Michael, Cohen, Aaron, Weichenthal, Scott, Coggins, Jay, Di, Qian, Brunekreef, Bert, Frostad, Joseph, Lim, Stephen S, Kan, Haidong, Walker, Katherine D, Thurston, George D, Hayes, Richard B, Lim, Chris C, Turner, Michelle C, Jerrett, Michael, Krewski, Daniel, Gapstur, Susan M, Diver, W Ryan, Ostro, Bart, Goldberg, Debbie, Crouse, Daniel L, Martin, Randall V, Peters, Paul, Pinault, Lauren, Tjepkema, Michael, van Donkelaar, Aaron, Villeneuve, Paul J, Miller, Anthony B, Yin, Peng, Zhou, Maigeng, Wang, Lijun, Janssen, Nicole AH, Marra, Marten, Atkinson, Richard W, Tsang, Hilda, Quoc Thach, Thuan, Cannon, John B, Allen, Ryan T, Hart, Jaime E, Laden, Francine, Cesaroni, Giulia, Forastiere, Francesco, Weinmayr, Gudrun, Jaensch, Andrea, Nagel, Gabriele, Concin, Hans, and Spadaro, Joseph V

Subjects
Humans, Air Pollutants, Proportional Hazards Models, Bayes Theorem, Risk Assessment, Cohort Studies, Air Pollution, Environmental Exposure, Time Factors, Particulate Matter, Global Health, Global Burden of Disease, Noncommunicable Diseases, concentration, exposure, fine particulate matter, mortality, risk
Abstract

Exposure to ambient fine particulate matter (PM2.5) is a major global health concern. Quantitative estimates of attributable mortality are based on disease-specific hazard ratio models that incorporate risk information from multiple PM2.5 sources (outdoor and indoor air pollution from use of solid fuels and secondhand and active smoking), requiring assumptions about equivalent exposure and toxicity. We relax these contentious assumptions by constructing a PM2.5-mortality hazard ratio function based only on cohort studies of outdoor air pollution that covers the global exposure range. We modeled the shape of the association between PM2.5 and nonaccidental mortality using data from 41 cohorts from 16 countries-the Global Exposure Mortality Model (GEMM). We then constructed GEMMs for five specific causes of death examined by the global burden of disease (GBD). The GEMM predicts 8.9 million [95% confidence interval (CI): 7.5-10.3] deaths in 2015, a figure 30% larger than that predicted by the sum of deaths among the five specific causes (6.9; 95% CI: 4.9-8.5) and 120% larger than the risk function used in the GBD (4.0; 95% CI: 3.3-4.8). Differences between the GEMM and GBD risk functions are larger for a 20% reduction in concentrations, with the GEMM predicting 220% higher excess deaths. These results suggest that PM2.5 exposure may be related to additional causes of death than the five considered by the GBD and that incorporation of risk information from other, nonoutdoor, particle sources leads to underestimation of disease burden, especially at higher concentrations.

Published
2018

13. Long-term exposure to low ambient air pollution concentrations and mortality among 28 million people: results from seven large European cohorts within the ELAPSE project

Author

Stafoggia, Massimo, Oftedal, Bente, Chen, Jie, Rodopoulou, Sophia, Renzi, Matteo, Atkinson, Richard W, Bauwelinck, Mariska, Klompmaker, Jochem O, Mehta, Amar, Vienneau, Danielle, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Cesaroni, Giulia, de Hoogh, Kees, Fecht, Daniela, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla A, Jöckel, Karl-Heinz, Jørgensen, Jeanette T, Katsouyanni, Klea, Ketzel, Matthias, Kristoffersen, Doris Tove, Lager, Anton, Leander, Karin, Liu, Shuo, Ljungman, Petter L S, Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Raaschou-Nielsen, Ole, Rizzuto, Debora, Schramm, Sara, Schwarze, Per E, Severi, Gianluca, Sigsgaard, Torben, Strak, Maciek, van der Schouw, Yvonne T, Verschuren, Monique, Weinmayr, Gudrun, Wolf, Kathrin, Zitt, Emanuel, Samoli, Evangelia, Forastiere, Francesco, Brunekreef, Bert, Hoek, Gerard, and Janssen, Nicole A H

Published
2022
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14. Long-term exposure to low-level ambient air pollution and incidence of stroke and coronary heart disease: a pooled analysis of six European cohorts within the ELAPSE project

Author

Wolf, Kathrin, Hoffmann, Barbara, Andersen, Zorana J, Atkinson, Richard W, Bauwelinck, Mariska, Bellander, Tom, Brandt, Jørgen, Brunekreef, Bert, Cesaroni, Giulia, Chen, Jie, de Faire, Ulf, de Hoogh, Kees, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hvidtfeldt, Ulla Arthur, Janssen, Nicole A H, Jørgensen, Jeanette T, Katsouyanni, Klea, Ketzel, Matthias, Klompmaker, Jochem O, Lager, Anton, Liu, Shuo, MacDonald, Conor J, Magnusson, Patrik K E, Mehta, Amar J, Nagel, Gabriele, Oftedal, Bente, Pedersen, Nancy L, Pershagen, Göran, Raaschou-Nielsen, Ole, Renzi, Matteo, Rizzuto, Debora, Rodopoulou, Sophia, Samoli, Evangelia, van der Schouw, Yvonne T, Schramm, Sara, Schwarze, Per, Sigsgaard, Torben, Sørensen, Mette, Stafoggia, Massimo, Strak, Maciek, Tjønneland, Anne, Verschuren, W M Monique, Vienneau, Danielle, Weinmayr, Gudrun, Hoek, Gerard, Peters, Annette, and Ljungman, Petter L S

Published
2021
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15. Modeling multi-level survival data in multi-center epidemiological cohort studies: Applications from the ELAPSE project

Author

Samoli, Evangelia, Rodopoulou, Sophia, Hvidtfeldt, Ulla A., Wolf, Kathrin, Stafoggia, Massimo, Brunekreef, Bert, Strak, Maciej, Chen, Jie, Andersen, Zorana J., Atkinson, Richard, Bauwelinck, Mariska, Bellander, Tom, Brandt, Jørgen, Cesaroni, Giulia, Forastiere, Francesco, Fecht, Daniela, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, de Hoogh, Kees, Janssen, Nicole A.H., Ketzel, Matthias, Klompmaker, Jochem O., Liu, Shuo, Ljungman, Petter, Nagel, Gabriele, Oftedal, Bente, Pershagen, Göran, Peters, Annette, Raaschou-Nielsen, Ole, Renzi, Matteo, Kristoffersen, Doris T., Severi, Gianluca, Sigsgaard, Torben, Vienneau, Danielle, Weinmayr, Gudrun, Hoek, Gerard, and Katsouyanni, Klea

Published
2021
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16. Long-term exposure to fine particle elemental components and lung cancer incidence in the ELAPSE pooled cohort

Author

Hvidtfeldt, Ulla Arthur, Chen, Jie, Andersen, Zorana Jovanovic, Atkinson, Richard, Bauwelinck, Mariska, Bellander, Tom, Brandt, Jørgen, Brunekreef, Bert, Cesaroni, Giulia, Concin, Hans, Fecht, Daniela, Forastiere, Francesco, van Gils, Carla H., Gulliver, John, Hertel, Ole, Hoek, Gerard, Hoffmann, Barbara, de Hoogh, Kees, Janssen, Nicole, Jørgensen, Jeanette Therming, Katsouyanni, Klea, Jöckel, Karl-Heinz, Ketzel, Matthias, Klompmaker, Jochem O., Lang, Alois, Leander, Karin, Liu, Shuo, Ljungman, Petter L.S., Magnusson, Patrik K.E., Mehta, Amar Jayant, Nagel, Gabriele, Oftedal, Bente, Pershagen, Göran, Peter, Raphael Simon, Peters, Annette, Renzi, Matteo, Rizzuto, Debora, Rodopoulou, Sophia, Samoli, Evangelia, Schwarze, Per Everhard, Severi, Gianluca, Sigsgaard, Torben, Stafoggia, Massimo, Strak, Maciej, Vienneau, Danielle, Weinmayr, Gudrun, Wolf, Kathrin, and Raaschou-Nielsen, Ole

Published
2021
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17. Long-term low-level ambient air pollution exposure and risk of lung cancer – A pooled analysis of 7 European cohorts

Author

Hvidtfeldt, Ulla Arthur, Severi, Gianluca, Andersen, Zorana Jovanovic, Atkinson, Richard, Bauwelinck, Mariska, Bellander, Tom, Boutron-Ruault, Marie-Christine, Brandt, Jørgen, Brunekreef, Bert, Cesaroni, Giulia, Chen, Jie, Concin, Hans, Forastiere, Francesco, van Gils, Carla H., Gulliver, John, Hertel, Ole, Hoek, Gerard, Hoffmann, Barbara, de Hoogh, Kees, Janssen, Nicole, Jöckel, Karl-Heinz, Jørgensen, Jeanette Therming, Katsouyanni, Klea, Ketzel, Matthias, Klompmaker, Jochem O., Krog, Norun Hjertager, Lang, Alois, Leander, Karin, Liu, Shuo, Ljungman, Petter L.S., Magnusson, Patrik K.E., Mehta, Amar Jayant, Nagel, Gabriele, Oftedal, Bente, Pershagen, Göran, Peter, Raphael Simon, Peters, Annette, Renzi, Matteo, Rizzuto, Debora, Rodopoulou, Sophia, Samoli, Evangelia, Schwarze, Per Everhard, Sigsgaard, Torben, Simonsen, Mette Kildevæld, Stafoggia, Massimo, Strak, Maciek, Vienneau, Danielle, Weinmayr, Gudrun, Wolf, Kathrin, Raaschou-Nielsen, Ole, and Fecht, Daniela

Published
2021
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18. Long-term exposure to low-level air pollution and incidence of chronic obstructive pulmonary disease: The ELAPSE project

Author

Liu, Shuo, Jørgensen, Jeanette T., Ljungman, Petter, Pershagen, Göran, Bellander, Tom, Leander, Karin, Magnusson, Patrik K.E., Rizzuto, Debora, Hvidtfeldt, Ulla A., Raaschou-Nielsen, Ole, Wolf, Kathrin, Hoffmann, Barbara, Brunekreef, Bert, Strak, Maciej, Chen, Jie, Mehta, Amar, Atkinson, Richard W., Bauwelinck, Mariska, Varraso, Raphaëlle, Boutron-Ruault, Marie-Christine, Brandt, Jørgen, Cesaroni, Giulia, Forastiere, Francesco, Fecht, Daniela, Gulliver, John, Hertel, Ole, de Hoogh, Kees, Janssen, Nicole A.H., Katsouyanni, Klea, Ketzel, Matthias, Klompmaker, Jochem O., Nagel, Gabriele, Oftedal, Bente, Peters, Annette, Tjønneland, Anne, Rodopoulou, Sophia P., Samoli, Evangelia, Bekkevold, Terese, Sigsgaard, Torben, Stafoggia, Massimo, Vienneau, Danielle, Weinmayr, Gudrun, Hoek, Gerard, and Andersen, Zorana J.

Published
2021
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19. #506 Long-term exposure to air pollution and CKD-associated mortality: results from the pooled cohort of the European multicentre ELAPSE-study

Author

Zitt, Emanuel, primary, Kadelbach, Pauline, additional, Chen, Jie, additional, Jaensch, Andrea, additional, de Hoogh, Kees, additional, Andersen, Zorana J, additional, Samoli, Evangelia, additional, Brunekreef, Bert, additional, Hoek, Gerard, additional, Nagel, Gabriele, additional, and Weinmayr, Gudrun, additional

Published
2024
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20. Long-term exposure to several constituents and sources of PM 2.5 is associated with incidence of upper aerodigestive tract cancers but not gastric cancer: Results from the large pooled European cohort of the ELAPSE project.

Author

Weinmayr, Gudrun, Chen, Jie, Jaensch, Andrea, Skodda, Lea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K E, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Thurston, George, Hoek, Gerard, Raaschou-Nielsen, Ole, Nagel, Gabriele, Weinmayr, Gudrun, Chen, Jie, Jaensch, Andrea, Skodda, Lea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K E, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Thurston, George, Hoek, Gerard, Raaschou-Nielsen, Ole, and Nagel, Gabriele

Abstract

It is unclear whether cancers of the upper aerodigestive tract (UADT) and gastric cancer are related to air pollution, due to few studies with inconsistent results. The effects of particulate matter (PM) may vary across locations due to different source contributions and related PM compositions, and it is not clear which PM constituents/sources are most relevant from a consideration of overall mass concentration alone. We therefore investigated the association of UADT and gastric cancers with PM 2.5 elemental constituents and sources components indicative of different sources within a large multicentre population based epidemiological study. Cohorts with at least 10 cases per cohort led to ten and eight cohorts from five countries contributing to UADT- and gastric cancer analysis, respectively. Outcome ascertainment was based on cancer registry data or data of comparable quality. We assigned home address exposure to eight elemental constituents (Cu, Fe, K, Ni, S, Si, V and Zn) estimated from Europe-wide exposure models, and five source components identified by absolute principal component analysis (APCA). Cox regression models were run with age as time scale, stratified for sex and cohort and adjusted for relevant individual and neighbourhood level confounders. We observed 1139 UADT and 872 gastric cancer cases during a mean follow-up of 18.3 and 18.5 years, respectively. UADT cancer incidence was associated with all constituents except K in single element analyses. After adjustment for NO 2, only Ni and V remained associated with UADT. Residual oil combustion and traffic source components were associated with UADT cancer persisting in the multiple source model. No associations were found for any of the elements or source components and gastric cancer incidence. Our results indicate an association of several PM constituents indicative of different sources with UADT but not gastric cancer incidence with the most robust evidence for traffic and residual oil combust

Published
2024

21. Long-term exposure to several constituents and sources of PM 2.5 is associated with incidence of upper aerodigestive tract cancers but not gastric cancer: Results from the large pooled European cohort of the ELAPSE project.

Author

IRAS OH Epidemiology Chemical Agents, IRAS – One Health Chemical, Weinmayr, Gudrun, Chen, Jie, Jaensch, Andrea, Skodda, Lea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K E, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Thurston, George, Hoek, Gerard, Raaschou-Nielsen, Ole, Nagel, Gabriele, IRAS OH Epidemiology Chemical Agents, IRAS – One Health Chemical, Weinmayr, Gudrun, Chen, Jie, Jaensch, Andrea, Skodda, Lea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K E, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Thurston, George, Hoek, Gerard, Raaschou-Nielsen, Ole, and Nagel, Gabriele

Published
2024

22. Long-term exposure to air pollution and chronic kidney disease-associated mortality - results from the pooled cohort of the European multicentre ELAPSE-study

Author

IRAS OH Epidemiology Chemical Agents, IRAS – One Health Chemical, Kadelbach, Pauline, Weinmayr, Gudrun, Chen, Jie, Jaensch Dipl-Dok, Andrea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Cesaroni, Giulia, Fecht, Daniela, Forastiere, Prof Francesco, Gulliver, Prof John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Prof Klea, Ketzel, Matthias, Leander, Karin, Ljungman, Petter, Magnusson, Patrik K E, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Prof Anne, Vermeulen, Roel, Peters, Annette, Wolf, Kathrin, Raaschou-Nielsen, Prof Ole, Brunekreef, Bert, Hoek, Gerard, Zitt, Emanuel, Nage, Prof Gabriele, IRAS OH Epidemiology Chemical Agents, IRAS – One Health Chemical, Kadelbach, Pauline, Weinmayr, Gudrun, Chen, Jie, Jaensch Dipl-Dok, Andrea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Cesaroni, Giulia, Fecht, Daniela, Forastiere, Prof Francesco, Gulliver, Prof John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Prof Klea, Ketzel, Matthias, Leander, Karin, Ljungman, Petter, Magnusson, Patrik K E, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Prof Anne, Vermeulen, Roel, Peters, Annette, Wolf, Kathrin, Raaschou-Nielsen, Prof Ole, Brunekreef, Bert, Hoek, Gerard, Zitt, Emanuel, and Nage, Prof Gabriele

Published
2024

23. Long-term exposure to ambient air pollution and risk of leukemia and lymphoma in a pooled European cohort

Author

IRAS OH Epidemiology Chemical Agents, IRAS – One Health Chemical, Taj, Tahir, Chen, Jie, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Poulsen, Aslak Harbo, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Zitt, Emanuel, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Jørgensen, Jeanette T., Katsouyanni, Klea, Ketzel, Matthias, Lager, Anton, Leander, Karin, Liu, Shuo, Ljungman, Petter, Severi, Gianluca, Besson, Caroline, Magnusson, Patrik K.E., Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Rizzuto, Debora, Samoli, Evangelia, Sørensen, Mette, Stafoggia, Massimo, Tjønneland, Anne, Weinmayr, Gudrun, Wolf, Kathrin, Brunekreef, Bert, Hoek, Gerard, Raaschou-Nielsen, Ole, IRAS OH Epidemiology Chemical Agents, IRAS – One Health Chemical, Taj, Tahir, Chen, Jie, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Poulsen, Aslak Harbo, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Zitt, Emanuel, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Jørgensen, Jeanette T., Katsouyanni, Klea, Ketzel, Matthias, Lager, Anton, Leander, Karin, Liu, Shuo, Ljungman, Petter, Severi, Gianluca, Besson, Caroline, Magnusson, Patrik K.E., Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Rizzuto, Debora, Samoli, Evangelia, Sørensen, Mette, Stafoggia, Massimo, Tjønneland, Anne, Weinmayr, Gudrun, Wolf, Kathrin, Brunekreef, Bert, Hoek, Gerard, and Raaschou-Nielsen, Ole

Published
2024

24. Long-term exposure to air pollution and incidence of gastric and the upper aerodigestive tract cancers in a pooled European cohort: The ELAPSE project

Author

IRAS OH Epidemiology Chemical Agents, IRAS – One Health Chemical, Nagel, Gabriele, Chen, Jie, Jaensch, Andrea, Skodda, Lea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K E, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel C H, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Hoek, Gerard, Raaschou-Nielsen, Ole, Weinmayr, Gudrun, IRAS OH Epidemiology Chemical Agents, IRAS – One Health Chemical, Nagel, Gabriele, Chen, Jie, Jaensch, Andrea, Skodda, Lea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K E, Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel C H, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Hoek, Gerard, Raaschou-Nielsen, Ole, and Weinmayr, Gudrun

Published
2024

25. Climate action has valuable health benefits

Author

Roca-Barceló, Aina, Rice, Mary B., Nunez, Yanelli, Thurston, George, Weinmayr, Gudrun, Straif, Kurt, Roscoe, Charlotte, Ebi, Kristie L., Andersen, Zorana Jovanovic, De Nazelle, Audrey, Negev, Maya, Roca-Barceló, Aina, Rice, Mary B., Nunez, Yanelli, Thurston, George, Weinmayr, Gudrun, Straif, Kurt, Roscoe, Charlotte, Ebi, Kristie L., Andersen, Zorana Jovanovic, De Nazelle, Audrey, and Negev, Maya

Abstract

The negative impacts of global climate change are well-known, but the health benefits of climate mitigation actions and their high monetary valuations are less appreciated. Actions to reduce the use of fossil fuels and greenhouse gas (GHG) emissions from energy production, industry, transportation, and agriculture will also bring major benefits to public health (see Figure 1).1 Economic benefits from health care savings and improved population health can far exceed the cost of climate mitigation measures. Cities, regions, and countries that implement climate change mitigation actions will gain immediate and long-term economic benefits of these health improvements.

Published
2024

26. Long-term exposure to several constituents and sources of PM2.5 is associated with incidence of upper aerodigestive tract cancers but not gastric cancer:Results from the large pooled European cohort of the ELAPSE project

Author

Weinmayr, Gudrun, Chen, Jie, Jaensch, Andrea, Skodda, Lea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K.E., Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Thurston, George, Hoek, Gerard, Raaschou-Nielsen, Ole, Nagel, Gabriele, Weinmayr, Gudrun, Chen, Jie, Jaensch, Andrea, Skodda, Lea, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla Arthur, Katsouyanni, Klea, Ketzel, Matthias, Leander, Karin, Magnusson, Patrik K.E., Pershagen, Göran, Rizzuto, Debora, Samoli, Evangelia, Severi, Gianluca, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Wolf, Kathrin, Zitt, Emanuel, Brunekreef, Bert, Thurston, George, Hoek, Gerard, Raaschou-Nielsen, Ole, and Nagel, Gabriele

Abstract

It is unclear whether cancers of the upper aerodigestive tract (UADT) and gastric cancer are related to air pollution, due to few studies with inconsistent results. The effects of particulate matter (PM) may vary across locations due to different source contributions and related PM compositions, and it is not clear which PM constituents/sources are most relevant from a consideration of overall mass concentration alone. We therefore investigated the association of UADT and gastric cancers with PM2.5 elemental constituents and sources components indicative of different sources within a large multicentre population based epidemiological study. Cohorts with at least 10 cases per cohort led to ten and eight cohorts from five countries contributing to UADT- and gastric cancer analysis, respectively. Outcome ascertainment was based on cancer registry data or data of comparable quality. We assigned home address exposure to eight elemental constituents (Cu, Fe, K, Ni, S, Si, V and Zn) estimated from Europe-wide exposure models, and five source components identified by absolute principal component analysis (APCA). Cox regression models were run with age as time scale, stratified for sex and cohort and adjusted for relevant individual and neighbourhood level confounders. We observed 1139 UADT and 872 gastric cancer cases during a mean follow-up of 18.3 and 18.5 years, respectively. UADT cancer incidence was associated with all constituents except K in single element analyses. After adjustment for NO2, only Ni and V remained associated with UADT. Residual oil combustion and traffic source components were associated with UADT cancer persisting in the multiple source model. No associations were found for any of the elements or source components and gastric cancer incidence. Our results indicate an association of several PM constituents indicative of different sources with UADT but not gastric cancer incidence with the most robust evidence for t, It is unclear whether cancers of the upper aerodigestive tract (UADT) and gastric cancer are related to air pollution, due to few studies with inconsistent results. The effects of particulate matter (PM) may vary across locations due to different source contributions and related PM compositions, and it is not clear which PM constituents/sources are most relevant from a consideration of overall mass concentration alone. We therefore investigated the association of UADT and gastric cancers with PM2.5 elemental constituents and sources components indicative of different sources within a large multicentre population based epidemiological study. Cohorts with at least 10 cases per cohort led to ten and eight cohorts from five countries contributing to UADT- and gastric cancer analysis, respectively. Outcome ascertainment was based on cancer registry data or data of comparable quality. We assigned home address exposure to eight elemental constituents (Cu, Fe, K, Ni, S, Si, V and Zn) estimated from Europe-wide exposure models, and five source components identified by absolute principal component analysis (APCA). Cox regression models were run with age as time scale, stratified for sex and cohort and adjusted for relevant individual and neighbourhood level confounders. We observed 1139 UADT and 872 gastric cancer cases during a mean follow-up of 18.3 and 18.5 years, respectively. UADT cancer incidence was associated with all constituents except K in single element analyses. After adjustment for NO2, only Ni and V remained associated with UADT. Residual oil combustion and traffic source components were associated with UADT cancer persisting in the multiple source model. No associations were found for any of the elements or source components and gastric cancer incidence. Our results indicate an association of several PM constituents indicative of different sources with UADT but not gastric cancer incidence with the most robust evidence for traffic and

Published
2024

28. Long-term exposure to ambient air pollution and risk of leukemia and lymphoma in a pooled European cohort

Author

Taj, Tahir, primary, Chen, Jie, additional, Rodopoulou, Sophia, additional, Strak, Maciej, additional, de Hoogh, Kees, additional, Poulsen, Aslak Harbo, additional, Andersen, Zorana J., additional, Bellander, Tom, additional, Brandt, Jørgen, additional, Zitt, Emanuel, additional, Fecht, Daniela, additional, Forastiere, Francesco, additional, Gulliver, John, additional, Hertel, Ole, additional, Hoffmann, Barbara, additional, Hvidtfeldt, Ulla Arthur, additional, Jørgensen, Jeanette T., additional, Katsouyanni, Klea, additional, Ketzel, Matthias, additional, Lager, Anton, additional, Leander, Karin, additional, Liu, Shuo, additional, Ljungman, Petter, additional, Severi, Gianluca, additional, Besson, Caroline, additional, Magnusson, Patrik K.E., additional, Nagel, Gabriele, additional, Pershagen, Göran, additional, Peters, Annette, additional, Rizzuto, Debora, additional, Samoli, Evangelia, additional, Sørensen, Mette, additional, Stafoggia, Massimo, additional, Tjønneland, Anne, additional, Weinmayr, Gudrun, additional, Wolf, Kathrin, additional, Brunekreef, Bert, additional, Hoek, Gerard, additional, and Raaschou-Nielsen, Ole, additional

Published
2023
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29. Particulate matter air pollution components and incidence of cancers of the stomach and the upper aerodigestive tract in the European Study of Cohorts of Air Pollution Effects (ESCAPE)

Author

Weinmayr, Gudrun, Pedersen, Marie, Stafoggia, Massimo, Andersen, Zorana J., Galassi, Claudia, Munkenast, Jule, Jaensch, Andrea, Oftedal, Bente, Krog, Norun H., Aamodt, Geir, Pyko, Andrei, Pershagen, Göran, Korek, Michal, De Faire, Ulf, Pedersen, Nancy L., Östenson, Claes-Göran, Rizzuto, Debora, Sørensen, Mette, Tjønneland, Anne, Bueno-de-Mesquita, Bas, Vermeulen, Roel, Eeftens, Marloes, Concin, Hans, Lang, Alois, Wang, Meng, Tsai, Ming-Yi, Ricceri, Fulvio, Sacerdote, Carlotta, Ranzi, Andrea, Cesaroni, Giulia, Forastiere, Francesco, de Hoogh, Kees, Beelen, Rob, Vineis, Paolo, Kooter, Ingeborg, Sokhi, Ranjeet, Brunekreef, Bert, Hoek, Gerard, Raaschou-Nielsen, Ole, and Nagel, Gabriele

Published
2018
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31. Is There an Association Between Ambient Air Pollution and Bladder Cancer Incidence? Analysis of 15 European Cohorts

Author

Pedersen, Marie, Stafoggia, Massimo, Weinmayr, Gudrun, Andersen, Zorana J., Galassi, Claudia, Sommar, Johan, Forsberg, Bertil, Olsson, David, Oftedal, Bente, Krog, Norun H., Aamodt, Geir, Pyko, Andrei, Pershagen, Göran, Korek, Michal, De Faire, Ulf, Pedersen, Nancy L., Östenson, Claes-Göran, Fratiglioni, Laura, Sørensen, Mette, Eriksen, Kirsten T., Tjønneland, Anne, Peeters, Petra H., Bueno-de-Mesquita, Bas, Vermeulen, Roel, Eeftens, Marloes, Plusquin, Michelle, Key, Timothy J., Jaensch, Andrea, Nagel, Gabriele, Concin, Hans, Wang, Meng, Tsai, Ming-Yi, Grioni, Sara, Marcon, Alessandro, Krogh, Vittorio, Ricceri, Fulvio, Sacerdote, Carlotta, Ranzi, Andrea, Cesaroni, Giulia, Forastiere, Francesco, Tamayo, Ibon, Amiano, Pilar, Dorronsoro, Miren, Stayner, Leslie T., Kogevinas, Manolis, Nieuwenhuijsen, Mark J., Sokhi, Ranjeet, de Hoogh, Kees, Beelen, Rob, Vineis, Paolo, Brunekreef, Bert, Hoek, Gerard, and Raaschou-Nielsen, Ole

Published
2018
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32. Long-term exposure to several constituents and sources of PM2.5 is associated with incidence of upper aerodigestive tract cancers but not gastric cancer: Results from the large pooled European cohort of the ELAPSE project

Author

Weinmayr, Gudrun, primary, Chen, Jie, additional, Jaensch, Andrea, additional, Skodda, Lea, additional, Rodopoulou, Sophia, additional, Strak, Maciej, additional, de Hoogh, Kees, additional, Andersen, Zorana J., additional, Bellander, Tom, additional, Brandt, Jørgen, additional, Fecht, Daniela, additional, Forastiere, Francesco, additional, Gulliver, John, additional, Hertel, Ole, additional, Hoffmann, Barbara, additional, Hvidtfeldt, Ulla Arthur, additional, Katsouyanni, Klea, additional, Ketzel, Matthias, additional, Leander, Karin, additional, Magnusson, Patrik K.E., additional, Pershagen, Göran, additional, Rizzuto, Debora, additional, Samoli, Evangelia, additional, Severi, Gianluca, additional, Stafoggia, Massimo, additional, Tjønneland, Anne, additional, Vermeulen, Roel, additional, Wolf, Kathrin, additional, Zitt, Emanuel, additional, Brunekreef, Bert, additional, Thurston, George, additional, Hoek, Gerard, additional, Raaschou-Nielsen, Ole, additional, and Nagel, Gabriele, additional

Published
2023
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33. Long-term exposure to air pollution and mortality due to chronic kidney disease – results from the multicentre ELAPSE-study

Author

Weinmayr, Gudrun, primary, Kadelbach, Pauline, additional, Chen, Jie, additional, Jaensch, Andrea, additional, Cesaroni, Giulia, additional, Fecht, Daniela, additional, Hoek, Gerard, additional, Hoogh, Kees De, additional, Andersen, Zorana J, additional, Bellander, Tom, additional, Hoffmann, Barbara, additional, Ljungman, Petter, additional, Nielsen, Ole Raaschou, additional, Samoli, Evangelia, additional, Stafoggia, Massimo, additional, Strak, Maciej, additional, Wolf, Kathrin, additional, Zitt, Emanuel, additional, Brunekreef, Bert, additional, and Nagel, Gabriele, additional

Published
2023
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34. Ambient air pollution and primary liver cancer incidence in four European cohorts within the ESCAPE project

Author

Pedersen, Marie, Andersen, Zorana J., Stafoggia, Massimo, Weinmayr, Gudrun, Galassi, Claudia, Sørensen, Mette, Eriksen, Kirsten T., Tjønneland, Anne, Loft, Steffen, Jaensch, Andrea, Nagel, Gabriele, Concin, Hans, Tsai, Ming-Yi, Grioni, Sara, Marcon, Alessandro, Krogh, Vittorio, Ricceri, Fulvio, Sacerdote, Carlotta, Ranzi, Andrea, Sokhi, Ranjeet, Vermeulen, Roel, Hoogh, Kees de, Wang, Meng, Beelen, Rob, Vineis, Paolo, Brunekreef, Bert, Hoek, Gerard, and Raaschou-Nielsen, Ole

Published
2017
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36. The Mediating Role of Self-Regulation and Self-Efficacy on Physical Activity Change in Community-Dwelling Older Adults (≥65 Years): An Experimental Cross-Lagged Analysis Using Data From SITLESS.

Author

McMullan, Ilona I., Bunting, Brendan P., Blackburn, Nicole E., Wilson, Jason J., Deidda, Manuela, Caserotti, Paolo, Smith, Lee, Dallmeier, Dhayana, Roque, Marta, Weinmayr, Gudrun, Giné-Garriga, Maria, Coll-Planas, Laura, and Tully, Mark A.

Subjects
SOCIAL determinants of health, SOCIAL support, SELF-management (Psychology), PHYSICAL activity, SELF-efficacy, INDEPENDENT living, DESCRIPTIVE statistics, BEHAVIOR modification, SECONDARY analysis
Abstract

Improving the capacity for physical activity interventions to maintain behavior change is a key public health concern and an important strategy for the health and independence of older adults. Ways of ensuring effective maintenance of physical activity levels in older adults are unclear. This study includes the objective measure of moderate-to-vigorous physical activity (MVPA); self-reported self-efficacy; and self-regulation at four timepoints (baseline, intervention completion at 4 months, 12-, and 18-month follow-up) from the SITLESS study, a clinical trial conducted with a cohort of community-dwelling older adults (≥65 years) from Denmark, Germany, Spain, and the United Kingdom. A cross-lagged analysis found that self-regulation and self-efficacy may be key determinants of MVPA behavior in community-dwelling older adults. More specifically, the use of behavioral support strategies represents an important correlate of MVPA behavior, and its association with MVPA may be mediated by self-regulation and self-efficacy in older adults in the short and long term. [ABSTRACT FROM AUTHOR]

Published
2021
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37. Corrigendum to ‘Exposure to ambient air pollution and elevated blood levels of gammaglutamyl transferase in a large Austrian cohort’ [Sci. Total Environ.883 (2023) 163658]

Author

Wirsching, Jan, primary, Nagel, Gabriele, additional, Tsai, Ming-Yi, additional, de Hoogh, Kees, additional, Jaensch, Andrea, additional, Anwander, Bernhard, additional, Sokhi, Ranjeet S., additional, Ulmer, Hanno, additional, Zitt, Emanuel, additional, Concin, Hans, additional, Brunekreef, Bert, additional, Hoek, Gerard, additional, and Weinmayr, Gudrun, additional

Published
2023
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38. Development of West-European PM2.5 and NO2 land use regression models incorporating satellite-derived and chemical transport modelling data

Author

de Hoogh, Kees, Gulliver, John, Donkelaar, Aaron van, Martin, Randall V., Marshall, Julian D., Bechle, Matthew J., Cesaroni, Giulia, Pradas, Marta Cirach, Dedele, Audrius, Eeftens, Marloes, Forsberg, Bertil, Galassi, Claudia, Heinrich, Joachim, Hoffmann, Barbara, Jacquemin, Bénédicte, Katsouyanni, Klea, Korek, Michal, Künzli, Nino, Lindley, Sarah J., Lepeule, Johanna, Meleux, Frederik, de Nazelle, Audrey, Nieuwenhuijsen, Mark, Nystad, Wenche, Raaschou-Nielsen, Ole, Peters, Annette, Peuch, Vincent-Henri, Rouil, Laurence, Udvardy, Orsolya, Slama, Rémy, Stempfelet, Morgane, Stephanou, Euripides G., Tsai, Ming Y., Yli-Tuomi, Tarja, Weinmayr, Gudrun, Brunekreef, Bert, Vienneau, Danielle, and Hoek, Gerard

Published
2016
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40. Long-term air pollution exposure and Parkinson's disease mortality in a large pooled European cohort: An ELAPSE study

Author

Planetary Health & Exposoom, Cancer, Circulatory Health, Cole-Hunter, Thomas, Zhang, Jiawei, So, Rina, Samoli, Evangelia, Liu, Shuo, Chen, Jie, Strak, Maciej, Wolf, Kathrin, Weinmayr, Gudrun, Rodopolou, Sophia, Remfry, Elizabeth, de Hoogh, Kees, Bellander, Tom, Brandt, Jørgen, Concin, Hans, Zitt, Emanuel, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hoffmann, Barbara, Hvidtfeldt, Ulla A., Jöckel, Karl Heinz, Mortensen, Laust H., Ketzel, Matthias, Yacamán Méndez, Diego, Leander, Karin, Ljungman, Petter, Faure, Elodie, Lee, Pei Chen, Elbaz, Alexis, Magnusson, Patrik K.E., Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Rizzuto, Debora, Vermeulen, Roel C.H., Schramm, Sara, Stafoggia, Massimo, Katsouyanni, Klea, Brunekreef, Bert, Hoek, Gerard, Lim, Youn Hee, Andersen, Zorana J., Planetary Health & Exposoom, Cancer, Circulatory Health, Cole-Hunter, Thomas, Zhang, Jiawei, So, Rina, Samoli, Evangelia, Liu, Shuo, Chen, Jie, Strak, Maciej, Wolf, Kathrin, Weinmayr, Gudrun, Rodopolou, Sophia, Remfry, Elizabeth, de Hoogh, Kees, Bellander, Tom, Brandt, Jørgen, Concin, Hans, Zitt, Emanuel, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hoffmann, Barbara, Hvidtfeldt, Ulla A., Jöckel, Karl Heinz, Mortensen, Laust H., Ketzel, Matthias, Yacamán Méndez, Diego, Leander, Karin, Ljungman, Petter, Faure, Elodie, Lee, Pei Chen, Elbaz, Alexis, Magnusson, Patrik K.E., Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Rizzuto, Debora, Vermeulen, Roel C.H., Schramm, Sara, Stafoggia, Massimo, Katsouyanni, Klea, Brunekreef, Bert, Hoek, Gerard, Lim, Youn Hee, and Andersen, Zorana J.

Published
2023

41. Long-term air pollution exposure and Parkinson's disease mortality in a large pooled European cohort: An ELAPSE study

Author

IRAS OH Epidemiology Chemical Agents, Cole-Hunter, Thomas, Zhang, Jiawei, So, Rina, Samoli, Evangelia, Liu, Shuo, Chen, Jie, Strak, Maciej, Wolf, Kathrin, Weinmayr, Gudrun, Rodopolou, Sophia, Remfry, Elizabeth, de Hoogh, Kees, Bellander, Tom, Brandt, Jørgen, Concin, Hans, Zitt, Emanuel, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hoffmann, Barbara, Hvidtfeldt, Ulla A, Jöckel, Karl-Heinz, Mortensen, Laust H, Ketzel, Matthias, Yacamán Méndez, Diego, Leander, Karin, Ljungman, Petter, Faure, Elodie, Lee, Pei-Chen, Elbaz, Alexis, Magnusson, Patrik K E, Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Rizzuto, Debora, Vermeulen, Roel C H, Schramm, Sara, Stafoggia, Massimo, Katsouyanni, Klea, Brunekreef, Bert, Hoek, Gerard, Lim, Youn-Hee, Andersen, Zorana J, IRAS OH Epidemiology Chemical Agents, Cole-Hunter, Thomas, Zhang, Jiawei, So, Rina, Samoli, Evangelia, Liu, Shuo, Chen, Jie, Strak, Maciej, Wolf, Kathrin, Weinmayr, Gudrun, Rodopolou, Sophia, Remfry, Elizabeth, de Hoogh, Kees, Bellander, Tom, Brandt, Jørgen, Concin, Hans, Zitt, Emanuel, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hoffmann, Barbara, Hvidtfeldt, Ulla A, Jöckel, Karl-Heinz, Mortensen, Laust H, Ketzel, Matthias, Yacamán Méndez, Diego, Leander, Karin, Ljungman, Petter, Faure, Elodie, Lee, Pei-Chen, Elbaz, Alexis, Magnusson, Patrik K E, Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Rizzuto, Debora, Vermeulen, Roel C H, Schramm, Sara, Stafoggia, Massimo, Katsouyanni, Klea, Brunekreef, Bert, Hoek, Gerard, Lim, Youn-Hee, and Andersen, Zorana J

Published
2023

42. Breast cancer incidence in relation to long-term low-level exposure to air pollution in the ELAPSE pooled cohort

Author

IRAS OH Epidemiology Chemical Agents, Hvidtfeldt, Ulla Arthur, Chen, Jie, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara H, Katsouyanni, Klea, Ketzel, Matthias, Brynedal, Boel, Leander, Karin, Ljungman, Petter L S, Magnusson, Patrik K E, Nagel, Gabriele, Pershagen, Göran, Rizzuto, Debora, Boutron-Ruault, Marie-Christine, Samoli, Evangelia, So, Rina, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Verschuren, W M Monique, Weinmayr, Gudrun, Wolf, Kathrin, Zhang, Jiawei, Zitt, Emanuel, Brunekreef, Bert, Hoek, Gerard, Raaschou-Nielsen, Ole, IRAS OH Epidemiology Chemical Agents, Hvidtfeldt, Ulla Arthur, Chen, Jie, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara H, Katsouyanni, Klea, Ketzel, Matthias, Brynedal, Boel, Leander, Karin, Ljungman, Petter L S, Magnusson, Patrik K E, Nagel, Gabriele, Pershagen, Göran, Rizzuto, Debora, Boutron-Ruault, Marie-Christine, Samoli, Evangelia, So, Rina, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Verschuren, W M Monique, Weinmayr, Gudrun, Wolf, Kathrin, Zhang, Jiawei, Zitt, Emanuel, Brunekreef, Bert, Hoek, Gerard, and Raaschou-Nielsen, Ole

Published
2023

43. Reply to Rumrich and colleagues (What does “Parkinson’s disease mortality” mean?)

Author

Cole-Hunter, Thomas, Zhang, Jiawei, Lim, Youn-Hee, Samoli, Evangelia, Chen, Jie, Strak, Maciej, Wolf, Kathrin, Weinmayr, Gudrun, Zitt, Emanuel, Hoffmann, Barbara, Jöckel, Karl-Heinz, Mortensen, Laust H, Ketzel, Matthias, Méndez, Diego Yacamán, Ljungman, Petter, Nagel, Gabriele, Pershagen, Göran, Rizzuto, Debora, Schramm, Sara, Brunekreef, Bert, Hoek, Gerard, Andersen, Zorana J, Cole-Hunter, Thomas, Zhang, Jiawei, Lim, Youn-Hee, Samoli, Evangelia, Chen, Jie, Strak, Maciej, Wolf, Kathrin, Weinmayr, Gudrun, Zitt, Emanuel, Hoffmann, Barbara, Jöckel, Karl-Heinz, Mortensen, Laust H, Ketzel, Matthias, Méndez, Diego Yacamán, Ljungman, Petter, Nagel, Gabriele, Pershagen, Göran, Rizzuto, Debora, Schramm, Sara, Brunekreef, Bert, Hoek, Gerard, and Andersen, Zorana J

Abstract

We thank Rumrich and colleagues for their interest and correspondence concerning our recently published article investigating the effects of long-term air pollution exposure on Parkinson’s disease (PD) mortality in a large pooled European (ELAPSE project) cohort (Cole-Hunter, 2023). In response, we agree that in general a more careful discussion of results is warranted due to the fact that air pollution as a specific risk factor is under-studied within the context of neurodegenerative diseases; hence, studies such as ours need to be performed albeit with some inherent limitations. Prior to our study, only two studies had examined long-term exposure to air pollution with respect to PD mortality, with one detecting significant positive associations for O3 (Zhao, 2021), and another finding a suggestive positive association for PM2.5 (Rhew et al., 2021). Most studies have examined PD incidence with mixed results (see Supplemental Table S1 of our original article (Cole-Hunter, 2023).

Published
2023

44. Long-term air pollution exposure and Parkinson's disease mortality in a large pooled European cohort:An ELAPSE study

Author

Cole-Hunter, Thomas, Zhang, Jiawei, So, Rina, Samoli, Evangelia, Liu, Shuo, Chen, Jie, Strak, Maciej, Wolf, Kathrin, Weinmayr, Gudrun, Rodopolou, Sophia, Remfry, Elizabeth, de Hoogh, Kees, Bellander, Tom, Brandt, Jørgen, Concin, Hans, Zitt, Emanuel, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hoffmann, Barbara, Hvidtfeldt, Ulla A, Jöckel, Karl-Heinz, Mortensen, Laust H, Ketzel, Matthias, Yacamán Méndez, Diego, Leander, Karin, Ljungman, Petter, Faure, Elodie, Lee, Pei-Chen, Elbaz, Alexis, Magnusson, Patrik K E, Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Rizzuto, Debora, Vermeulen, Roel C H, Schramm, Sara, Stafoggia, Massimo, Katsouyanni, Klea, Brunekreef, Bert, Hoek, Gerard, Lim, Youn-Hee, Andersen, Zorana J, Cole-Hunter, Thomas, Zhang, Jiawei, So, Rina, Samoli, Evangelia, Liu, Shuo, Chen, Jie, Strak, Maciej, Wolf, Kathrin, Weinmayr, Gudrun, Rodopolou, Sophia, Remfry, Elizabeth, de Hoogh, Kees, Bellander, Tom, Brandt, Jørgen, Concin, Hans, Zitt, Emanuel, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hoffmann, Barbara, Hvidtfeldt, Ulla A, Jöckel, Karl-Heinz, Mortensen, Laust H, Ketzel, Matthias, Yacamán Méndez, Diego, Leander, Karin, Ljungman, Petter, Faure, Elodie, Lee, Pei-Chen, Elbaz, Alexis, Magnusson, Patrik K E, Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Rizzuto, Debora, Vermeulen, Roel C H, Schramm, Sara, Stafoggia, Massimo, Katsouyanni, Klea, Brunekreef, Bert, Hoek, Gerard, Lim, Youn-Hee, and Andersen, Zorana J

Abstract

BACKGROUND: The link between exposure to ambient air pollution and mortality from cardiorespiratory diseases is well established, while evidence on neurodegenerative disorders including Parkinson's Disease (PD) remains limited.OBJECTIVE: We examined the association between long-term exposure to ambient air pollution and PD mortality in seven European cohorts.METHODS: Within the project 'Effects of Low-Level Air Pollution: A Study in Europe' (ELAPSE), we pooled data from seven cohorts among six European countries. Annual mean residential concentrations of fine particulate matter (PM 2.5), nitrogen dioxide (NO 2), black carbon (BC), and ozone (O 3), as well as 8 PM 2.5 components (copper, iron, potassium, nickel, sulphur, silicon, vanadium, zinc), for 2010 were estimated using Europe-wide hybrid land use regression models. PD mortality was defined as underlying cause of death being either PD, secondary Parkinsonism, or dementia in PD. We applied Cox proportional hazard models to investigate the associations between air pollution and PD mortality, adjusting for potential confounders. RESULTS: Of 271,720 cohort participants, 381 died from PD during 19.7 years of follow-up. In single-pollutant analyses, we observed positive associations between PD mortality and PM 2.5 (hazard ratio per 5 µg/m 3: 1.25; 95% confidence interval: 1.01-1.55), NO 2 (1.13; 0.95-1.34 per 10 µg/m 3), and BC (1.12; 0.94-1.34 per 0.5 × 10 -5m -1), and a negative association with O 3 (0.74; 0.58-0.94 per 10 µg/m 3). Associations of PM 2.5, NO 2, and BC with PD mortality were linear without apparent lower thresholds. In two-pollutant models, associations with PM 2.5 remained robust when adjusted for NO 2 (1.24; 0.95-1.62) or BC (1.28; 0.96-1.71), whereas associations with NO 2 or BC attenuated to null. O 3 associations remained negative, but no longer statistically significant in models with PM 2.5. We detected suggestive positive associations with the potassium component of P

Published
2023

45. Breast Cancer Incidence in Relation to Long-Term Low-Level Exposure to Air Pollution in the ELAPSE Pooled Cohort

Author

Planetary Health & Exposoom, Cancer, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Cardiometabolic Health, Hvidtfeldt, Ulla Arthur, Chen, Jie, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara H., Katsouyanni, Klea, Ketzel, Matthias, Brynedal, Boel, Leander, Karin, Ljungman, Petter L.S., Magnusson, Patrik K.E., Nagel, Gabriele, Pershagen, Göran, Rizzuto, Debora, Boutron-Ruault, Marie Christine, Samoli, Evangelia, So, Rina, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Verschuren, W. M.Monique, Weinmayr, Gudrun, Wolf, Kathrin, Zhang, Jiawei, Zitt, Emanuel, Brunekreef, Bert, Hoek, Gerard, Raaschou-Nielsen, Ole, Planetary Health & Exposoom, Cancer, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Cardiometabolic Health, Hvidtfeldt, Ulla Arthur, Chen, Jie, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J., Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara H., Katsouyanni, Klea, Ketzel, Matthias, Brynedal, Boel, Leander, Karin, Ljungman, Petter L.S., Magnusson, Patrik K.E., Nagel, Gabriele, Pershagen, Göran, Rizzuto, Debora, Boutron-Ruault, Marie Christine, Samoli, Evangelia, So, Rina, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Verschuren, W. M.Monique, Weinmayr, Gudrun, Wolf, Kathrin, Zhang, Jiawei, Zitt, Emanuel, Brunekreef, Bert, Hoek, Gerard, and Raaschou-Nielsen, Ole

Published
2023

46. Reply to Rumrich and colleagues (What does “Parkinson’s disease mortality” mean?)

Author

Cole-Hunter, Thomas, primary, Zhang, Jiawei, additional, Lim, Youn-Hee, additional, Samoli, Evangelia, additional, Chen, Jie, additional, Strak, Maciej, additional, Wolf, Kathrin, additional, Weinmayr, Gudrun, additional, Zitt, Emanuel, additional, Hoffmann, Barbara, additional, Jöckel, Karl-Heinz, additional, Mortensen, Laust H., additional, Ketzel, Matthias, additional, Méndez, Diego Yacamán, additional, Ljungman, Petter, additional, Nagel, Gabriele, additional, Pershagen, Göran, additional, Rizzuto, Debora, additional, Schramm, Sara, additional, Brunekreef, Bert, additional, Hoek, Gerard, additional, and Andersen, Zorana J., additional

Published
2023
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48. Breast cancer incidence in relation to long-term low-level exposure to air pollution in the ELAPSE pooled cohort

Author

Hvidtfeldt, Ulla Arthur, Chen, Jie, Rodopoulou, Sophia, Strak, Maciej, de Hoogh, Kees, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hoffmann, Barbara H, Katsouyanni, Klea, Ketzel, Matthias, Brynedal, Boel, Leander, Karin, Ljungman, Petter L S, Magnusson, Patrik K E, Nagel, Gabriele, Pershagen, Göran, Rizzuto, Debora, Boutron-Ruault, Marie-Christine, Samoli, Evangelia, So, Rina, Stafoggia, Massimo, Tjønneland, Anne, Vermeulen, Roel, Verschuren, W M Monique, Weinmayr, Gudrun, Wolf, Kathrin, Zhang, Jiawei, Zitt, Emanuel, Brunekreef, Bert, Hoek, Gerard, Raaschou-Nielsen, Ole, IRAS OH Epidemiology Chemical Agents, and IRAS OH Epidemiology Chemical Agents

Subjects
Epidemiology, Population, MODELS, Nitrogen Dioxide, Dioxide, Breast Neoplasms, PM2.5, PROFILE, Ozone, Life, Models, Pm2.5, Air Pollution, Humans, Women, POPULATION, 11 Medical and Health Sciences, Public, Environmental & Occupational Health, ELAPSE, Gesundheitseffekte von Luftschadstoffen, Medicine(all), Air Pollutants, Science & Technology, Incidence, WOMEN, Men, MEN, Environmental Exposure, Middle Aged, Risk-factors, LIFE, Oncology, Health, RISK-FACTORS, Profile, Female, Particulate Matter, HEALTH, Life Sciences & Biomedicine, DIOXIDE
Abstract

Background: Established risk factors for breast cancer include genetic disposition, reproductive factors, hormone therapy, and lifestyle-related factors such as alcohol consumption, physical inactivity, smoking, and obesity. More recently a role of environmental exposures, including air pollution, has also been suggested. The aim of this study, was to investigate the relationship between long-term air pollution exposure and breast cancer incidence. Methods: We conducted a pooled analysis among six European cohorts (n = 199,719) on the association between long-term residential levels of ambient nitrogen dioxide (NO2), fine particles (PM2.5), black carbon (BC), and ozone in the warm season (O3) and breast cancer incidence in women. The selected cohorts represented the lower range of air pollutant concentrations in Europe. We applied Cox proportional hazards models adjusting for potential confounders at the individual and area-level. Results: During 3,592,885 person-years of follow-up, we observed a total of 9,659 incident breast cancer cases. The results of the fully adjusted linear analyses showed a HR (95% confidence interval) of 1.03 (1.00–1.06) per 10 μg/m³ NO2, 1.06 (1.01–1.11) per 5 μg/m³ PM2.5, 1.03 (0.99–1.06) per 0.5 10−5 m−1 BC, and 0.98 (0.94–1.01) per 10 μg/m³ O3. The effect estimates were most pronounced in the group of middle-aged women (50–54 years) and among never smokers. Conclusions: The results were in support of an association between especially PM2.5 and breast cancer. Impact: The findings of this study suggest a role of exposure to NO2, PM2.5, and BC in development of breast cancer.

Published
2023
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50. Long-term exposure to elemental constituents of particulate matter and cardiovascular mortality in 19 European cohorts: Results from the ESCAPE and TRANSPHORM projects

Author

Wang, Meng, Beelen, Rob, Stafoggia, Massimo, Raaschou-Nielsen, Ole, Andersen, Zorana Jovanovic, Hoffmann, Barbara, Fischer, Paul, Houthuijs, Danny, Nieuwenhuijsen, Mark, Weinmayr, Gudrun, Vineis, Paolo, Xun, Wei W., Dimakopoulou, Konstantina, Samoli, Evangelia, Laatikainen, Tiina, Lanki, Timo, Turunen, Anu W., Oftedal, Bente, Schwarze, Per, Aamodt, Geir, Penell, Johanna, De Faire, Ulf, Korek, Michal, Leander, Karin, Pershagen, Göran, Pedersen, Nancy L., Östenson, Claes-Göran, Fratiglioni, Laura, Eriksen, Kirsten Thorup, Sørensen, Mette, Tjønneland, Anne, Bueno-de-Mesquita, Bas, Eeftens, Marloes, Bots, Michiel L., Meliefste, Kees, Krämer, Ursula, Heinrich, Joachim, Sugiri, Dorothea, Key, Timothy, de Hoogh, Kees, Wolf, Kathrin, Peters, Annette, Cyrys, Josef, Jaensch, Andrea, Concin, Hans, Nagel, Gabriele, Tsai, Ming-Yi, Phuleria, Harish, Ineichen, Alex, Künzli, Nino, Probst-Hensch, Nicole, Schaffner, Emmanuel, Vilier, Alice, Clavel-Chapelon, Françoise, Declerq, Christophe, Ricceri, Fulvio, Sacerdote, Carlotta, Marcon, Alessandro, Galassi, Claudia, Migliore, Enrica, Ranzi, Andrea, Cesaroni, Giulia, Badaloni, Chiara, Forastiere, Francesco, Katsoulis, Michail, Trichopoulou, Antonia, Keuken, Menno, Jedynska, Aleksandra, Kooter, Ingeborg M., Kukkonen, Jaakko, Sokhi, Ranjeet S., Brunekreef, Bert, Katsouyanni, Klea, and Hoek, Gerard

Published
2014
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