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185 results on '"Weitmann, Kerstin"'

1. The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies

Author

Hoffmann, Julia, Hanß, Sabine, Kraus, Monika, Schaller, Jens, Schäfer, Christian, Stahl, Dana, Anker, Stefan D., Anton, Gabriele, Bahls, Thomas, Blankenberg, Stefan, Blumentritt, Arne, Boldt, Leif-Hendrik, Cordes, Steffen, Desch, Steffen, Doehner, Wolfram, Dörr, Marcus, Edelmann, Frank, Eitel, Ingo, Endres, Matthias, Engelhardt, Stefan, Erdmann, Jeanette, Eulenburg, Katharina, Falk, Volkmar, Felix, Stephan B., Frank, Derk, Franke, Thomas, Frey, Norbert, Friede, Tim, Geidel, Lars, Germans, Lisa, Grabmaier, Ulrich, Halle, Martin, Hausleiter, Jörg, Jakobi, Vera, Jebran, Ahmad-Fawad, Jobs, Alexander, Kääb, Stefan, Karakas, Mahir, Katus, Hugo A., Klatt, Alexandra, Knosalla, Christoph, Krebser, Joachim, Landmesser, Ulf, Lee, Mahsa, Lehnert, Kristin, Lesser, Stephanie, Leyh, Katrin, Lorbeer, Roberto, Mach-Kolb, Stephanie, Meder, Benjamin, Nagel, Eike, Nolte, Christian H., Parwani, Abdul S., Petersmann, Astrid, Puls, Miriam, Rau, Henriette, Reiser, Maximilian, Rienhoff, Otto, Scharfe, Tabea, Schattschneider, Mario, Scheel, Heiko, Schnabel, Renate B., Schuster, Andreas, Schmitt, Boris, Seidler, Tim, Seiffert, Moritz, Stähli, Barbara-Elisabeth, Stas, Adriane, J. Stocker, Thomas, von Stülpnagel, Lukas, Thiele, Holger, Wachter, Rolf, Wakili, Reza, Weis, Tanja, Weitmann, Kerstin, Wichmann, Heinz-Erich, Wild, Philipp, Zeller, Tanja, Hoffmann, Wolfgang, Zeisberg, Elisabeth Maria, Zimmermann, Wolfram-Hubertus, Krefting, Dagmar, Kühne, Titus, Peters, Annette, Hasenfuß, Gerd, Massberg, Steffen, Sommer, Thomas, Dimmeler, Stefanie, Eschenhagen, Thomas, and Nauck, Matthias

Published
2023
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6. Population-Based Clinical Cancer Registration in Germany

Author

Katalinic, Alexander, primary, Halber, Marco, additional, Meyer, Martin, additional, Pflüger, Maren, additional, Eberle, Andrea, additional, Nennecke, Alice, additional, Kim-Wanner, Soo-Zin, additional, Hartz, Tobias, additional, Weitmann, Kerstin, additional, Stang, Andreas, additional, Justenhoven, Christina, additional, Holleczek, Bernd, additional, Piontek, Daniela, additional, Wittenberg, Ian, additional, Heßmer, Annika, additional, Kraywinkel, Klaus, additional, Spix, Claudia, additional, and Pritzkuleit, Ron, additional

Published
2023
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8. Supplementary Figure S1 from L-Carnitine–Mediated Tumor Cell Protection and Poor Patient Survival Associated with OCTN2 Overexpression in Glioblastoma Multiforme

Author

Fink, Matthias A., primary, Paland, Heiko, primary, Herzog, Susann, primary, Grube, Markus, primary, Vogelgesang, Silke, primary, Weitmann, Kerstin, primary, Bialke, Angela, primary, Hoffmann, Wolfgang, primary, Rauch, Bernhard H., primary, Schroeder, Henry W.S., primary, and Bien-Möller, Sandra, primary

Published
2023
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9. Supplementary Text from L-Carnitine–Mediated Tumor Cell Protection and Poor Patient Survival Associated with OCTN2 Overexpression in Glioblastoma Multiforme

Author

Fink, Matthias A., primary, Paland, Heiko, primary, Herzog, Susann, primary, Grube, Markus, primary, Vogelgesang, Silke, primary, Weitmann, Kerstin, primary, Bialke, Angela, primary, Hoffmann, Wolfgang, primary, Rauch, Bernhard H., primary, Schroeder, Henry W.S., primary, and Bien-Möller, Sandra, primary

Published
2023
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15. Erratum to: Changes of myocardial gene expression and protein composition in patients with dilated cardiomyopathy after immunoadsorption with subsequent immunoglobulin substitution

Author

Ameling, Sabine, Bhardwaj, Gourav, Hammer, Elke, Beug, Daniel, Steil, Leif, Reinke, Yvonne, Weitmann, Kerstin, Grube, Markus, Trimpert, Christiane, Klingel, Karin, Kandolf, Reinhard, Hoffmann, Wolfgang, Nauck, Matthias, Dörr, Marcus, Empen, Klaus, Felix, Stephan B., and Völker, Uwe

Published
2017
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19. Changes of myocardial gene expression and protein composition in patients with dilated cardiomyopathy after immunoadsorption with subsequent immunoglobulin substitution

Author

Ameling, Sabine, Bhardwaj, Gourav, Hammer, Elke, Beug, Daniel, Steil, Leif, Reinke, Yvonne, Weitmann, Kerstin, Grube, Markus, Trimpert, Christiane, Klingel, Karin, Kandolf, Reinhard, Hoffmann, Wolfgang, Nauck, Matthias, Dörr, Marcus, Empen, Klaus, Felix, Stephan B., and Völker, Uwe

Published
2016
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26. Sugars make the difference – Glycosylation of cardiodepressant antibodies regulates their activity in dilated cardiomyopathy

Author

Reinke, Yvonne, primary, Könemann, Stephanie, additional, Chamling, Bishwas, additional, Gross, Stefan, additional, Weitmann, Kerstin, additional, Hoffmann, Wolfgang, additional, Klingel, Karin, additional, Nauck, Matthias, additional, Fielitz, Jens, additional, Dörr, Marcus, additional, and Felix, Stephan B., additional

Published
2019
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27. Data privacy management and data quality monitoring in the German Centre for Cardiovascular Research's multicentre TranslatiOnal Registry for CardiomyopatHies (DZHK‐TORCH)

Author

Schwaneberg, Thea, Weitmann, Kerstin, Dösch, Andreas, Seyler, Claudia, Bahls, Thomas, Geidel, Lars, Stahl, Dana, Lee, Mahsa, Kraus, Monika, Katus, Hugo A., and Hoffmann, Wolfgang

Subjects
Male, Registry, Informed Consent, Cardiomyopathy, Middle Aged, Data Accuracy, Translational Research, Biomedical, Central data management, Knowledge Management, Privacy, Original Research Articles, Germany, Humans, Female, Original Research Article, Registries, Quality management, Morbidity, Cardiomyopathies
Abstract

Aims The multicentric TranslatiOnal Registry for CardiomyopatHies (TORCH) of the German Centre for Cardiovascular Research aims to recruit 2300 patients with non‐ischemic cardiomyopthies. Methods and results The investigations were performed after standard operating procedures. The data are collected in standardized electronic case report forms provided by the data holding of the central data management of the German Centre for Cardiovascular Research using secuTrial (interActive Systems GmbH, Berlin, Germany). The personal‐identifying data and informed consent are collected, stored, and quality‐checked by the independent Trusted Third Party in Greifswald. The quality management of the medical data is performed by the data and quality centre Greifswald. In December 2014, the recruitment for TORCH has started. Currently, data and biomaterial from about 1397 patients and more than 74 500 biomaterial aliquots were collected. Regular study centre‐specific quality reports address completeness and plausibility of data and provide detailed information about current missing or implausible data entries to improve the data quality by using a query management in addition. Conclusions A regular quality control and reporting improve the data quality in TORCH and will support high‐quality data analysis and the translation of research results into routine care.

Published
2017

28. Population-Based Analysis of the Impact of Demographics on the Current and Future Blood Supply in the Saarland.

Author

Eichler, Hermann, Feyer, Anna Katharina, Weitmann, Kerstin, Hoffmann, Wolfgang, Henseler, Olaf, Opitz, Andreas, Patek, Alexander, Hans, Detlef Nikolaus, Schönborn, Linda, and Greinacher, Andreas

Abstract

Background: The federal state of Saarland (SL) is experiencing the fastest demographic change in the western part of Germany. In this study, we analyzed retrospective data on the current and future supply of red blood cell concentrates (RBC) in this region and compared it to the current and future RBC demand in SL hospitals. Methods: The projection of the SL blood supply in 2030 was modeled based on SL demographics for age distribution and donation frequency of donors, and the RBC transfusion data for in-house patients. These results were compared to published data on the transfusion demand from the state of Mecklenburg-Western Pomerania (MV). Results: For the period January 1 to December 31, 2017, a total of 43,205 whole blood donations were collected. The donation frequency in SL never exceeded 80 per 1,000 inhabitants and was well below the numbers in MV. Thirty-one percent of the donors were responsible for 53.5% of the donations, and donors older than 45 years of age contributed highly to the total blood supply. In addition, 40,614 RBC transfusions at 10 SL hospitals were analyzed representing nearly all RBC transfusions for in-house patients in this region. RBC transfusions per 1,000 inhabitants increased with age from 24 (50–54) to 140 (80–84) years. Facing an already existing structural deficit of nearly 8,200 RBC in 2017, the projection predicts a dramatic increase in the regional deficit to >18,300 RBC in 2030. Conclusion: Our results on RBC demand in SL are comparable but not identical to those projected for the region of MV in eastern Germany. Due to the ongoing demographic changes in Germany as a whole, regular regional monitoring of RBC demand and the age structure of blood recipients and donors should be implemented to allow for better strategic planning in blood transfusion services and hospitals. [ABSTRACT FROM AUTHOR]

Published
2021
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30. L-Carnitine–Mediated Tumor Cell Protection and Poor Patient Survival Associated with OCTN2 Overexpression in Glioblastoma Multiforme

Author

Fink, Matthias A., primary, Paland, Heiko, additional, Herzog, Susann, additional, Grube, Markus, additional, Vogelgesang, Silke, additional, Weitmann, Kerstin, additional, Bialke, Angela, additional, Hoffmann, Wolfgang, additional, Rauch, Bernhard H., additional, Schroeder, Henry W.S., additional, and Bien-Möller, Sandra, additional

Published
2019
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31. Benefit einer Treuhandstelle für die klinische Krebsregistrierung

Author

Bialke, Angela, Weitmann, Kerstin, and Hoffmann, Wolfgang

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Mit dem Krebsfrüherkennungs- und -registergesetz wurde 2013 die Weiterentwicklung der Krebsfrüherkennung und Qualitätssicherung durch klinische Krebsregister (KKR) vorangetrieben. Es legt u.a. die Einrichtung fachlich und institutionell unabhängiger KKR sowie die Grundlagen[zum vollständigen Text gelangen Sie über die oben angegebene URL], 16. Deutscher Kongress für Versorgungsforschung (DKVF)

Published
2017
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32. Herausforderungen einer Zusammenführung der Tumordokumentationsdatenbanken mehrerer Klinischer Krebsregister

Author

Kullik, Martin, Weitmann, Kerstin, Gebauer, Alexander, and Hoffmann, Wolfgang

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: In Mecklenburg-Vorpommern sind seit den 90er Jahren vier flächendeckende, regionale Klinische Krebsregister (KKR) etabliert. Für die digitale Tumordokumentation wird in allen vier KKR das Gießender Tumordokumentationssystem (GTDS) eingesetzt, welches individuelle Anpassungen,[zum vollständigen Text gelangen Sie über die oben angegebene URL], 16. Deutscher Kongress für Versorgungsforschung (DKVF)

Published
2017

34. Association of Glioblastoma Multiforme Stem Cell Characteristics, Differentiation, and Microglia Marker Genes with Patient Survival

Author

Bien-Möller, Sandra, primary, Balz, Ellen, additional, Herzog, Susann, additional, Plantera, Laura, additional, Vogelgesang, Silke, additional, Weitmann, Kerstin, additional, Seifert, Carolin, additional, Fink, Matthias A., additional, Marx, Sascha, additional, Bialke, Angela, additional, Venugopal, Chitra, additional, Singh, Sheila K., additional, Hoffmann, Wolfgang, additional, Rauch, Bernhard H., additional, and Schroeder, Henry W. S., additional

Published
2018
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43. Expression of S1P metabolizing enzymes and receptors correlate with survival time and regulate cell migration in glioblastoma multiforme

Author

Bien-Möller, Sandra, primary, Lange, Sandra, additional, Holm, Tobias, additional, Böhm, Andreas, additional, Paland, Heiko, additional, Küpper, Johannes, additional, Herzog, Susann, additional, Weitmann, Kerstin, additional, Havemann, Christoph, additional, Vogelgesang, Silke, additional, Marx, Sascha, additional, Hoffmann, Wolfgang, additional, Schroeder, Henry W.S., additional, and Rauch, Bernhard H., additional

Published
2016
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44. Influence of quartz exposure on lung cancer types in cases of lymph node-only silicosis and lung silicosis in German uranium miners.

Author

Mielke, Stefan, Taeger, Dirk, Weitmann, Kerstin, Brüning, Thomas, and Hoffmann, Wolfgang

Subjects
QUARTZ crystals, CARCINOGENS, LUNG cancer, SILICOSIS, LYMPH nodes, URANIUM miners, GERMANS, HEALTH
Abstract

Inhaled crystalline quartz is a carcinogen. Analyses show differences in the distribution of lung cancer types depending on the status of silicosis. Using 2,524 lung tumor cases from the WISMUT autopsy repository database, silicosis was differentiated into cases without silicosis in lung parenchyma and its lymph nodes, with lymph node-only silicosis, or with lung silicosis including lymph node silicosis. The proportions of adenocarcinoma, squamous cell carcinoma, and small-cell lung carcinoma mortality for increasing quartz exposures were estimated in a multinomial logistic regression model. The relative proportions of the lung cancer subtypes in lymph node-only silicosis were more similar to lung silicosis than without any silicosis. The results support the hypothesis that quartz-related carcinogenesis in case of lymph node-only silicosis is more similar to that in lung silicosis than in without silicosis. [ABSTRACT FROM AUTHOR]

Published
2018
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47. Breastfeeding motivation in Pomerania: Survey of neonates in Pomerania (SNiP- Study).

Author

Lange, Anja, Nautsch, Anke, Weitmann, Kerstin, Ittermann, Till, and Heckmann, Matthias

Abstract

Background: The Nationale Stillkommission was founded in Germany in 1994 to increase the acceptance of breastfeeding as the primary means of infant nutrition. Scientific studies like "Stillen und Säuglingsernährung (SuSe-Studie)", and regional studies in Bavaria, Freiburg, Hamburg, and Berlin demonstrated breastfeeding initiation rates of 90 to 95%, but the total breastfeeding rate decreased to 25-61% after infants were 6 months old. One predictor of breastfeeding duration may be maternal motivation. The present study aimed to describe breastfeeding motivation. Methods: We analysed data collected in 2004-2008, during a previous study, the Survey of Neonates in Pomerania (SNiP). We retrieved data regarding maternal breastfeeding motivation, family environment, and socioeconomic factors. We constructed a quantitative breastfeeding-motivation score to identify factors involved in maternal breastfeeding. Results: Ninety five percent of mothers who gave birth in the study period and area provided information in the survey. The breastfeeding initiation rate was 88.4%. Mothers' intentions to provide exclusive breastfeeding (only breast milk, no other liquids or infant formula) increased linearly from 71.9% in 2005 to 76.8% in 2008. Women motivated to provide exclusive breastfeeding were, on average, older, primiparous, and able to deliver spontaneously more often than women with less breastfeeding motivation. Furthermore, women with no motivation to provide exclusive breastfeeding and women that intended to provide breastfeeding combined with a complementary nutrition source had visited prenatal classes less frequently, had lower levels education, had lower average incomes, had a German nationality more often, and used tobacco more often than women motivated to provide exclusive breastfeeding. Conclusions: Breastfeeding intentions increased during the SNiP Study. This study identified several factors that might serve for targeted breastfeeding promotion in mothers younger than 25 years, mothers with low education, and multiparous mothers or women who have received a caesarean section. Furthermore, breastfeeding motivation might be enhanced during pregnancy and/or after delivery by providing prenatal classes. [ABSTRACT FROM AUTHOR]

Published
2017

48. Pim1 kinase is upregulated in glioblastoma multiforme and mediates tumor cell survival

Author

Herzog, Susann, primary, Fink, Matthias Alexander, additional, Weitmann, Kerstin, additional, Friedel, Claudius, additional, Hadlich, Stefan, additional, Langner, Sönke, additional, Kindermann, Katharina, additional, Holm, Tobias, additional, Böhm, Andreas, additional, Eskilsson, Eskil, additional, Miletic, Hrvoje, additional, Hildner, Markus, additional, Fritsch, Michael, additional, Vogelgesang, Silke, additional, Havemann, Christoph, additional, Ritter, Christoph Alexander, additional, Meyer zu Schwabedissen, Henriette Elisabeth, additional, Rauch, Bernhard, additional, Hoffmann, Wolfgang, additional, Kroemer, Heyo Klaus, additional, Schroeder, Henry, additional, and Bien-Möller, Sandra, additional

Published
2014
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49. Stiffness of Left Ventricular Cardiac Fibroblasts Is Associated With Ventricular Dilation in Patients With Recent-Onset Nonischemic and Nonvalvular Cardiomyopathy

Author

Glaubitz, Michael, primary, Block, Stephan, additional, Witte, Jeannine, additional, Empen, Klaus, additional, Gross, Stefan, additional, Schlicht, Robert, additional, Weitmann, Kerstin, additional, Klingel, Karin, additional, Kandolf, Reinhard, additional, Hoffmann, Wolfgang, additional, Gottschalk, Kay E., additional, Busch, Mathias, additional, Dörr, Marcus, additional, Helm, Christiane A., additional, Felix, Stephan B., additional, and Riad, Alexander, additional

Published
2014
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50. Epigenetic modulation of the drug resistance genes MGMT, ABCB1 and ABCG2 in glioblastoma multiforme

Author

Oberstadt, Moritz C, primary, Bien-Möller, Sandra, additional, Weitmann, Kerstin, additional, Herzog, Susann, additional, Hentschel, Katharina, additional, Rimmbach, Christian, additional, Vogelgesang, Silke, additional, Balz, Ellen, additional, Fink, Matthias, additional, Michael, Heike, additional, Zeden, Jan-Philip, additional, Bruckmüller, Henrike, additional, Werk, Anneke N, additional, Cascorbi, Ingolf, additional, Hoffmann, Wolfgang, additional, Rosskopf, Dieter, additional, Schroeder, Henry WS, additional, and Kroemer, Heyo K, additional

Published
2013
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