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26 results on '"Wen, Haifei"'

4. Combining Multiple Photosensitizer Modules into One Supramolecular System for Synergetic Enhanced Photodynamic Therapy

Author

Li, Zhikai, primary, Zhang, Zhijun, additional, Ma, Lingzhi, additional, Wen, Haifei, additional, Kang, Miaomiao, additional, Li, Danxia, additional, Zhang, Wenjing, additional, Luo, Siqi, additional, Wang, Weiguo, additional, Zhang, Mingming, additional, Wang, Dong, additional, Li, Haiyang, additional, Li, Xiaopeng, additional, and Wang, Heng, additional

Published
2024
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14. Good Steel Used in the Blade: Well‐Tailored Type‐I Photosensitizers with Aggregation‐Induced Emission Characteristics for Precise Nuclear Targeting Photodynamic Therapy

Author

Kang, Miaomiao, primary, Zhang, Zhijun, additional, Xu, Wenhan, additional, Wen, Haifei, additional, Zhu, Wei, additional, Wu, Qian, additional, Wu, Hongzhuo, additional, Gong, Junyi, additional, Wang, Zhijia, additional, Wang, Dong, additional, and Tang, Ben Zhong, additional

Published
2021
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17. An All‐Round Athlete on the Track of Phototheranostics: Subtly Regulating the Balance between Radiative and Nonradiative Decays for Multimodal Imaging‐Guided Synergistic Therapy

Author

Zhang, Zhijun, primary, Xu, Wenhan, additional, Kang, Miaomiao, additional, Wen, Haifei, additional, Guo, Heng, additional, Zhang, Pengfei, additional, Xi, Lei, additional, Li, Kai, additional, Wang, Lei, additional, Wang, Dong, additional, and Tang, Ben Zhong, additional

Published
2020
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18. Making the Best Use of Excited-State Energy: Multimodality Theranostic Systems Based on Second Near-Infrared (NIR-II) Aggregation-Induced Emission Luminogens (AIEgens)

Author

Xu, Wenhan, primary, Zhang, Zhijun, additional, Kang, Miaomiao, additional, Guo, Heng, additional, Li, Youmei, additional, Wen, Haifei, additional, Lee, Michelle M. S., additional, Wang, Zhaoyu, additional, Kwok, Ryan T. K., additional, Lam, Jacky W. Y., additional, Li, Kai, additional, Xi, Lei, additional, Chen, Sijie, additional, Wang, Dong, additional, and Tang, Ben Zhong, additional

Published
2020
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19. Making the Best Use of Excited-State Energy: Multimodality Theranostic Systems Based on NIR-II AIEgens

Author

XU, Wenhan, primary, Zhang, Zhijun, primary, Kang, Miaomiao, primary, Guo, Heng, primary, Li, Youmei, primary, Wen, Haifei, primary, Lee, Michelle Mei Suet, primary, Wang, Zhaoyu, primary, Lam, Jacky W. Y., primary, Tsz Kin Kwok, Ryan, primary, Li, Kai, primary, Xi, Lei, primary, Chen, Sijie, primary, Wang, Dong, primary, and Tang, Ben Zhong, primary

Published
2020
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24. Fracturing Technology of Coalbed Methane in Qinshui Basin

Author

Wen Haifei, Zheng Donghong, Yue Taizhen, Zhou Hongyan, Wang Rui, Wu Tao, Lan Zhongxiao, Jin Xianpeng, Lan Chengyu, and Wang Wenjun

Subjects
Coalbed methane, Petroleum engineering, Structural basin, Fracture control, Geology
Abstract

Coalbed methane (CBM) reservoir with Lower Young's Modulus, higher Poisson's ratio, and lower permeability is different from conventional sandstone reservoir in composition, structure, tectonic and mechanical property, therefore, the fracturing technique and mechanism are much more different. Qinshui Basin located in the southeast of Shanxi Province is of simple synclinorium structure, less of faults, and it has up to 10 layers of coal seams, total thickness 1.2–23.6m and the maximum 6.5m. By far, No.3 and No.15 coal seam of Qinshui Basin have been developed for CBM production, depth from 600m to 900m, and the rank of the coal are mainly meager-lean coal and anthracite. No.3 coal seam of Shanxi Formation is 0.53–7.84m thick, gas content 11.94m3 / t on average, mainly semi-bright coal and semi-dull coal, reservoir pressure gradient 0.7149MPa/100m on average, well-testing permeability 1.589mD on average, Langmuir volume 39.03m3/t on average, Langmuir pressure 2.902 MPa. No.15 coal seam of Taiyuan Formation is 0.6– 9.9m thick, gas content 12.45m3/t on average, mainly bright coal and semi-bright coal, reservoir pressure gradient 0.7727MPa/100m on average, well-testing permeability 1.14mD on average, Langmuir volume 40.91m3/t, Langmuir pressure 2.5417 MPa. Through optimizing the fracturing designs, evaluating fracturing fluid systems and implementing control measures, a set of ‘network fracturing’ treatments with casing injection, high displacement and activated water fracturing fluid as key techniques were developed and applied successfully for coalbed methane in Qinshui Basin with the rate of success more than 95%. The study also showed that the multi-fracture treatment by plugging perforation with plastic ball can be used in separate layer treatment of coalbed methane reservoir. Furthermore, variable injection rate and slug injection of proppant can also be used to achieve the purpose of controlling extension of fractures. In five years,1264 layers (at 1096 wells) were treated by using this fracturing technology in QinShui Basin, and the gas production rate is over 2000 m3/d in 60% fracturing wells.

Published
2013

25. Combining Multiple Photosensitizer Modules into One Supramolecular System for Synergetic Enhanced Photodynamic Therapy.

Author

Li Z, Zhang Z, Ma L, Wen H, Kang M, Li D, Zhang W, Luo S, Wang W, Zhang M, Wang D, Li H, Li X, and Wang H

Subjects
Humans, Photosensitizing Agents therapeutic use, Reactive Oxygen Species, Photochemotherapy, Porphyrins pharmacology, Porphyrins therapeutic use, Neoplasms drug therapy
Abstract

Photodynamic therapy (PDT), as an emerging cancer treatment, requires the development of highly desirable photosensitizers (PSs) with integrated functional groups to achieve enhanced therapeutic efficacy. Coordination-driven self-assembly (CDSA) would provide an alternative approach for combining multiple PSs synergistically. Here, we demonstrate a simple yet powerful strategy of combining conventional chromophores (tetraphenylethylene, porphyrin, or Zn-porphyrin) with pyridinium salt PSs together through condensation reactions, followed by CDSA to construct a series of novel metallo-supramolecular PSs (S1-S3). The generation of reactive oxygen species (ROS) is dramatically enhanced by the direct combination of two different PSs, and further reinforced in the subsequent ensembles. Among all the ensembles, S2 with two porphyrin cores shows the highest ROS generation efficiency, specific interactions with lysosome, and strong emission for probing cells. Moreover, the cellular and living experiments confirm that S2 has excellent PDT efficacy, biocompatibility, and biosafety. As such, this study will enable the development of more efficient PSs with potential clinical applications., (© 2024 Wiley-VCH GmbH.)

Published
2024
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26. Reverse Thinking of the Aggregation-Induced Emission Principle: Amplifying Molecular Motions to Boost Photothermal Efficiency of Nanofibers*.

Author

Li H, Wen H, Zhang Z, Song N, Kwok RTK, Lam JWY, Wang L, Wang D, and Tang BZ

Abstract

Using reverse thinking of the aggregation-induced emission (AIE) principle, we demonstrate an ingenious and universal protocol for amplifying molecular motions to boost photothermal efficiency of fibers. Core-shell nanofibers having the olive oil solution of AIE-active molecules as the core surrounded by PVDF-HFP shell were constructed by coaxial electrospinning. The molecularly dissolved state of AIE-active molecules allows them to freely rotate and/or vibrate in nanofibers upon photoexcitation and thus significantly elevates the proportion of non-radiative energy dissipation, affording impressive heat-generating efficiency. Photothermal evaluation shows that the core-shell nanofibers with excellent durability can reach up to 22.36 % of photothermal conversion efficiency, which is 26-fold as the non-core-shell counterpart. Such a core-shell fiber can be used for photothermal textiles and solar steam generation induced by natural sunlight with green and carbon-zero emission., (© 2020 Wiley-VCH GmbH.)

Published
2020
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