5,367 results on '"Wen, Xing"'
Search Results
2. Blind Image Super-resolution with Rich Texture-Aware Codebooks
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Qin, Rui, Sun, Ming, Zhang, Fangyuan, Wen, Xing, and Wang, Bin
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Computer Science - Computer Vision and Pattern Recognition - Abstract
Blind super-resolution (BSR) methods based on high-resolution (HR) reconstruction codebooks have achieved promising results in recent years. However, we find that a codebook based on HR reconstruction may not effectively capture the complex correlations between low-resolution (LR) and HR images. In detail, multiple HR images may produce similar LR versions due to complex blind degradations, causing the HR-dependent only codebooks having limited texture diversity when faced with confusing LR inputs. To alleviate this problem, we propose the Rich Texture-aware Codebook-based Network (RTCNet), which consists of the Degradation-robust Texture Prior Module (DTPM) and the Patch-aware Texture Prior Module (PTPM). DTPM effectively mines the cross-resolution correlation of textures between LR and HR images by exploiting the cross-resolution correspondence of textures. PTPM uses patch-wise semantic pre-training to correct the misperception of texture similarity in the high-level semantic regularization. By taking advantage of this, RTCNet effectively gets rid of the misalignment of confusing textures between HR and LR in the BSR scenarios. Experiments show that RTCNet outperforms state-of-the-art methods on various benchmarks by up to 0.16 ~ 0.46dB.
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- 2023
3. Ada-DQA: Adaptive Diverse Quality-aware Feature Acquisition for Video Quality Assessment
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Liu, Hongbo, Wu, Mingda, Yuan, Kun, Sun, Ming, Tang, Yansong, Zheng, Chuanchuan, Wen, Xing, and Li, Xiu
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Computer Science - Computer Vision and Pattern Recognition - Abstract
Video quality assessment (VQA) has attracted growing attention in recent years. While the great expense of annotating large-scale VQA datasets has become the main obstacle for current deep-learning methods. To surmount the constraint of insufficient training data, in this paper, we first consider the complete range of video distribution diversity (\ie content, distortion, motion) and employ diverse pretrained models (\eg architecture, pretext task, pre-training dataset) to benefit quality representation. An Adaptive Diverse Quality-aware feature Acquisition (Ada-DQA) framework is proposed to capture desired quality-related features generated by these frozen pretrained models. By leveraging the Quality-aware Acquisition Module (QAM), the framework is able to extract more essential and relevant features to represent quality. Finally, the learned quality representation is utilized as supplementary supervisory information, along with the supervision of the labeled quality score, to guide the training of a relatively lightweight VQA model in a knowledge distillation manner, which largely reduces the computational cost during inference. Experimental results on three mainstream no-reference VQA benchmarks clearly show the superior performance of Ada-DQA in comparison with current state-of-the-art approaches without using extra training data of VQA., Comment: 10 pages, 5 figures, to appear in ACM MM 2023
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- 2023
4. Efficient access control scheme for heterogeneous signcryption based on blockchain in VANETs
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Khalafalla, Wael, Zhu, Wen-Xing, Elkhalil, Ahmed, and Elfadul, Issameldeen
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- 2024
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5. On the Solute Concentration and Corrosion Susceptibility of Mg-xMn-4.0Gd Alloy
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Gu, Dong-dong, Wu, Wen-xing, Xie, Shi-kun, and Peng, Jian
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- 2024
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6. Capturing Co-existing Distortions in User-Generated Content for No-reference Video Quality Assessment
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Yuan, Kun, Kong, Zishang, Zheng, Chuanchuan, Sun, Ming, and Wen, Xing
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Computer Science - Computer Vision and Pattern Recognition - Abstract
Video Quality Assessment (VQA), which aims to predict the perceptual quality of a video, has attracted raising attention with the rapid development of streaming media technology, such as Facebook, TikTok, Kwai, and so on. Compared with other sequence-based visual tasks (\textit{e.g.,} action recognition), VQA faces two under-estimated challenges unresolved in User Generated Content (UGC) videos. \textit{First}, it is not rare that several frames containing serious distortions (\textit{e.g.,}blocking, blurriness), can determine the perceptual quality of the whole video, while other sequence-based tasks require more frames of equal importance for representations. \textit{Second}, the perceptual quality of a video exhibits a multi-distortion distribution, due to the differences in the duration and probability of occurrence for various distortions. In order to solve the above challenges, we propose \textit{Visual Quality Transformer (VQT)} to extract quality-related sparse features more efficiently. Methodologically, a Sparse Temporal Attention (STA) is proposed to sample keyframes by analyzing the temporal correlation between frames, which reduces the computational complexity from $O(T^2)$ to $O(T \log T)$. Structurally, a Multi-Pathway Temporal Network (MPTN) utilizes multiple STA modules with different degrees of sparsity in parallel, capturing co-existing distortions in a video. Experimentally, VQT demonstrates superior performance than many \textit{state-of-the-art} methods in three public no-reference VQA datasets. Furthermore, VQT shows better performance in four full-reference VQA datasets against widely-adopted industrial algorithms (\textit{i.e.,} VMAF and AVQT)., Comment: 10 pages, 7 figures, to appear in ACM MM 2023
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- 2023
7. Reconstructed Convolution Module Based Look-Up Tables for Efficient Image Super-Resolution
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Liu, Guandu, Ding, Yukang, Li, Mading, Sun, Ming, Wen, Xing, and Wang, Bin
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Electrical Engineering and Systems Science - Image and Video Processing ,Computer Science - Computer Vision and Pattern Recognition - Abstract
Look-up table(LUT)-based methods have shown the great efficacy in single image super-resolution (SR) task. However, previous methods ignore the essential reason of restricted receptive field (RF) size in LUT, which is caused by the interaction of space and channel features in vanilla convolution. They can only increase the RF at the cost of linearly increasing LUT size. To enlarge RF with contained LUT sizes, we propose a novel Reconstructed Convolution(RC) module, which decouples channel-wise and spatial calculation. It can be formulated as $n^2$ 1D LUTs to maintain $n\times n$ receptive field, which is obviously smaller than $n\times n$D LUT formulated before. The LUT generated by our RC module reaches less than 1/10000 storage compared with SR-LUT baseline. The proposed Reconstructed Convolution module based LUT method, termed as RCLUT, can enlarge the RF size by 9 times than the state-of-the-art LUT-based SR method and achieve superior performance on five popular benchmark dataset. Moreover, the efficient and robust RC module can be used as a plugin to improve other LUT-based SR methods. The code is available at https://github.com/liuguandu/RC-LUT.
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- 2023
8. Towards Robust SDRTV-to-HDRTV via Dual Inverse Degradation Network
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Xu, Kepeng, Xu, Li, He, Gang, Yu, Wenxin, and Li, Yunsong
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Electrical Engineering and Systems Science - Image and Video Processing ,Computer Science - Multimedia - Abstract
In this study, we address the emerging necessity of converting Standard Dynamic Range Television (SDRTV) content into High Dynamic Range Television (HDRTV) in light of the limited number of native HDRTV content. A principal technical challenge in this conversion is the exacerbation of coding artifacts inherent in SDRTV, which detrimentally impacts the quality of the resulting HDRTV. To address this issue, our method introduces a novel approach that conceptualizes the SDRTV-to-HDRTV conversion as a composite task involving dual degradation restoration. This encompasses inverse tone mapping in conjunction with video restoration. We propose Dual Inversion Downgraded SDRTV to HDRTV Network (DIDNet), which can accurately perform inverse tone mapping while preventing encoding artifacts from being amplified, thereby significantly improving visual quality. DIDNet integrates an intermediate auxiliary loss function to effectively separate the dual degradation restoration tasks and efficient learning of both artifact reduction and inverse tone mapping during end-to-end training. Additionally, DIDNet introduces a spatio-temporal feature alignment module for video frame fusion, which augments texture quality and reduces artifacts. The architecture further includes a dual-modulation convolution mechanism for optimized inverse tone mapping. Recognizing the richer texture and high-frequency information in HDRTV compared to SDRTV, we further introduce a wavelet attention module to enhance frequency features. Our approach demonstrates marked superiority over existing state-of-the-art techniques in terms of quantitative performance and visual quality., Comment: 13 pages
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- 2023
9. Coherent manipulation of three-dimensional probe absorption spectrum in a strained GaAs-AlGaAs-InAs semiconductor quantum dot
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Ai, Le, Shi, Zhen-Yu, Shui, Tao, and Yang, Wen-Xing
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- 2024
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10. Functional Characterization of Verticillium dahliae Race 3-Specific Gene VdR3e in Virulence and Elicitation of Plant Immune Responses.
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Tan, Qian, Li, Ran, Liu, Lei, Wang, Dan, Dai, Xiao-Feng, Song, Li-Min, Zhang, Dan-Dan, Kong, Zhi-Qiang, Klosterman, Steve, Usami, Toshiyuki, Liang, Wen-Xing, Chen, Jie-Yin, and Subbarao, Krishna
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PAMPs ,Verticillium dahliae ,effector ,immunity ,pathogen-associated molecular pattern ,race ,virulence ,Virulence ,Verticillium ,Ascomycota ,Plant Immunity ,Virulence Factors ,Plant Diseases - Abstract
Verticillium dahliae is a soilborne fungal pathogen that causes disease on many economically important crops. Based on the resistance or susceptibility of differential cultivars in tomato, isolates of V. dahliae are divided into three races. Avirulence (avr) genes within the genomes of the three races have also been identified. However, the functional role of the avr gene in race 3 isolates of V. dahliae has not been characterized. In this study, bioinformatics analysis showed that VdR3e, a cysteine-rich secreted protein encoded by the gene characterizing race 3 in V. dahliae, was likely obtained by horizontal gene transfer from the fungal genus Bipolaris. We demonstrate that VdR3e causes cell death by triggering multiple defense responses. In addition, VdR3e localized at the periphery of the plant cell and triggered immunity depending on its subcellular localization and the cell membrane receptor BAK1. Furthermore, VdR3e is a virulence factor and shows differential pathogenicity in race 3-resistant and -susceptible hosts. These results suggest that VdR3e is a virulence factor that can also interact with BAK1 as a pathogen-associated molecular pattern (PAMP) to trigger immune responses. IMPORTANCE Based on the gene-for-gene model, research on the function of avirulence genes and resistance genes has had an unparalleled impact on breeding for resistance in most crops against individual pathogens. The soilborne fungal pathogen, Verticillium dahliae, is a major pathogen on many economically important crops. Currently, avr genes of the three races in V. dahliae have been identified, but the function of avr gene representing race 3 has not been described. We investigated the characteristics of VdR3e-mediated immunity and demonstrated that VdR3e acts as a PAMP to activate a variety of plant defense responses and induce plant cell death. We also demonstrated that the role of VdR3e in pathogenicity was host dependent. This is the first study to describe the immune and virulence functions of the avr gene from race 3 in V. dahliae, and we provide support for the identification of genes mediating resistance against race 3.
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- 2023
11. Landform and lithospheric development contribute to the assembly of mountain floras in China
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Wan-Yi Zhao, Zhong-Cheng Liu, Shi Shi, Jie-Lan Li, Ke-Wang Xu, Kang-You Huang, Zhi-Hui Chen, Ya-Rong Wang, Cui-Ying Huang, Yan Wang, Jing-Rui Chen, Xian-Ling Sun, Wen-Xing Liang, Wei Guo, Long-Yuan Wang, Kai-Kai Meng, Xu-Jie Li, Qian-Yi Yin, Ren-Chao Zhou, Zhao-Dong Wang, Hao Wu, Da-Fang Cui, Zhi-Yao Su, Guo-Rong Xin, Wei-Qiu Liu, Wen-Sheng Shu, Jian-Hua Jin, David E. Boufford, Qiang Fan, Lei Wang, Su-Fang Chen, and Wen-Bo Liao
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Science - Abstract
Abstract Although it is well documented that mountains tend to exhibit high biodiversity, how geological processes affect the assemblage of montane floras is a matter of ongoing research. Here, we explore landform-specific differences among montane floras based on a dataset comprising 17,576 angiosperm species representing 140 Chinese mountain floras, which we define as the collection of all angiosperm species growing on a specific mountain. Our results show that igneous bedrock (granitic and karst-granitic landforms) is correlated with higher species richness and phylogenetic overdispersion, while the opposite is true for sedimentary bedrock (karst, Danxia, and desert landforms), which is correlated with phylogenetic clustering. Furthermore, we show that landform type was the primary determinant of the assembly of evolutionarily older species within floras, while climate was a greater determinant for younger species. Our study indicates that landform type not only affects montane species richness, but also contributes to the composition of montane floras. To explain the assembly and differentiation of mountain floras, we propose the ‘floristic geo-lithology hypothesis’, which highlights the role of bedrock and landform processes in montane floristic assembly and provides insights for future research on speciation, migration, and biodiversity in montane regions.
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- 2024
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12. Zoom-VQA: Patches, Frames and Clips Integration for Video Quality Assessment
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Zhao, Kai, Yuan, Kun, Sun, Ming, and Wen, Xing
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Computer Science - Computer Vision and Pattern Recognition - Abstract
Video quality assessment (VQA) aims to simulate the human perception of video quality, which is influenced by factors ranging from low-level color and texture details to high-level semantic content. To effectively model these complicated quality-related factors, in this paper, we decompose video into three levels (\ie, patch level, frame level, and clip level), and propose a novel Zoom-VQA architecture to perceive spatio-temporal features at different levels. It integrates three components: patch attention module, frame pyramid alignment, and clip ensemble strategy, respectively for capturing region-of-interest in the spatial dimension, multi-level information at different feature levels, and distortions distributed over the temporal dimension. Owing to the comprehensive design, Zoom-VQA obtains state-of-the-art results on four VQA benchmarks and achieves 2nd place in the NTIRE 2023 VQA challenge. Notably, Zoom-VQA has outperformed the previous best results on two subsets of LSVQ, achieving 0.8860 (+1.0%) and 0.7985 (+1.9%) of SRCC on the respective subsets. Adequate ablation studies further verify the effectiveness of each component. Codes and models are released in https://github.com/k-zha14/Zoom-VQA., Comment: Accepted by CVPR 2023 Workshop
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- 2023
13. Quality-aware Pre-trained Models for Blind Image Quality Assessment
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Zhao, Kai, Yuan, Kun, Sun, Ming, Li, Mading, and Wen, Xing
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Computer Science - Computer Vision and Pattern Recognition - Abstract
Blind image quality assessment (BIQA) aims to automatically evaluate the perceived quality of a single image, whose performance has been improved by deep learning-based methods in recent years. However, the paucity of labeled data somewhat restrains deep learning-based BIQA methods from unleashing their full potential. In this paper, we propose to solve the problem by a pretext task customized for BIQA in a self-supervised learning manner, which enables learning representations from orders of magnitude more data. To constrain the learning process, we propose a quality-aware contrastive loss based on a simple assumption: the quality of patches from a distorted image should be similar, but vary from patches from the same image with different degradations and patches from different images. Further, we improve the existing degradation process and form a degradation space with the size of roughly $2\times10^7$. After pre-trained on ImageNet using our method, models are more sensitive to image quality and perform significantly better on downstream BIQA tasks. Experimental results show that our method obtains remarkable improvements on popular BIQA datasets., Comment: Accepted by CVPR 2023
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- 2023
14. A spatiotemporal network using a local spatial difference stack block for facial micro-expression recognition
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Liang, Yan, Hao, Yan, Liao, Jiacheng, Deng, Zhuoran, Wen, Xing, Zheng, Zefeng, and Pan, Jiahui
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- 2024
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15. Dynamical Regulation of Photosynthetic Components Related to Photosynthesis and Photoprotection in Maturing Blueberry Fruit
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Li, Xiaobai, Pan, Xuhao, Liu, Li, Wen, Xing, Jin, Liang, Yu, Fei, and Guo, Weidong
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- 2024
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16. Transcription Factor FOSL1 Promotes Angiogenesis of Colon Carcinoma by Regulating the VEGF Pathway Through Activating TIMP1
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Wang, Meng, Wang, Xian, Zhang, Yuanchuan, Gu, Jianhui, Zhang, Jie, and Wen, Xing
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- 2023
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17. Meta‑analysis of single-incision laparoscopic versus multi-trocar laparoscopic totally extraperitoneal inguinal hernia repair
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Wang, Deng-Chao, Fu, Jun-Wen, Jiang, Tao, Chen, Wen-Xing, and Yu, Miao
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- 2023
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18. Fast 3D face reconstruction from a single image combining attention mechanism and graph convolutional network
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Deng, Zhuoran, Liang, Yan, Pan, Jiahui, Liao, Jiacheng, Hao, Yan, and Wen, Xing
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- 2023
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19. Edge-cloud computing oriented large-scale online music education mechanism driven by neural networks
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Wen Xing, Adam Slowik, and J. Dinesh Peter
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Edge-cloud computing ,Large-scale information fusion ,Music recommendation ,Neural networks ,Computer engineering. Computer hardware ,TK7885-7895 ,Electronic computers. Computer science ,QA75.5-76.95 - Abstract
Abstract With the advent of the big data era, edge cloud computing has developed rapidly. In this era of popular digital music, various technologies have brought great convenience to online music education. But vast databases of digital music prevent educators from making specific-purpose choices. Music recommendation will be a potential development direction for online music education. In this paper, we propose a deep learning model based on multi-source information fusion for music recommendation under the scenario of edge-cloud computing. First, we use the music latent factor vector obtained by the Weighted Matrix Factorization (WMF) algorithm as the ground truth. Second, we build a neural network model to fuse multiple sources of music information, including music spectrum extracted from extra music information to predict the latent spatial features of music. Finally, we predict the user’s preference for music through the inner product of the user vector and the music vector for recommendation. Experimental results on public datasets and real music data collected by edge devices demonstrate the effectiveness of the proposed method in music recommendation.
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- 2024
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20. Prediction of the risk of severe small bowel obstruction and effects of Houpu Paiqi mixture in patients undergoing surgery for small bowel obstruction
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Ze-zheng Wang, Zhe-kui Liu, Wen-xing Ma, Yun-hua Wu, and Xiang-long Duan
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Severe small bowel obstruction ,Risk factors ,Houpu Paiqi mixture ,Prediction model ,Nomogram ,Surgery ,RD1-811 - Abstract
Abstract Aim Small bowel obstruction is a common condition that requires emergency surgery. Slow recovery of bowel function after surgery or the occurrence of one or more complications can exacerbate the disease and result in severe small bowel obstruction (SSBO), significantly impacting recovery. It is characterized by a failure to regain enteral nutrition promptly, requiring long-term intensive care. Therefore, it is necessary to identify factors that predict SSBO, to allow early intervention for patients likely to develop this condition. Methods Of the 260 patients who underwent emergency or elective surgery for small bowel obstruction between January 2018 and December 2022, 45 developed SSBO. The least absolute shrinkage and selection operator regression model was applied to optimize factor selection and multivariable logistic regression analysis was used to construct a predictive model. The performance and clinical utility of the nomogram were determined and internal validation was conducted. In addition, the effects of the Houpu Paiqi mixture on postoperative recovery were analyzed by comparing the clinical data of 28 patients who were treated with the mixture and 61patients who did not receive it. Results The predictors included in the prediction nomogram were age, peritonitis, intestinal resection and anastomosis, complications, operation time, Acute Physiology and Chronic Health Evaluation II score, white blood cell count, and procalcitonin level. The model had an area under the receiver operating characteristic curve of 0.948 (95% confidence interval: 0.814–0.956). Decision curve analysis demonstrated that the SSBO risk nomogram had a good net clinical benefit. In addition, treatment with the Houpu Paiqi mixture reduced postoperative exhaust time, postoperative defecation time, time to first postoperative liquid feed, and length of stay in hospital. Conclusions We developed a nomogram that can assist clinicians in identifying patients at greater risk of SSBO, which may aid in early diagnosis and intervention. Additionally, we found that the Houpu Paiqi mixture promoted postoperative recovery.
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- 2024
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21. Niche Modification by Sulfate-Reducing Bacteria Drives Microbial Community Assembly in Anoxic Marine Sediments
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Liang, Qi-Yun, Zhang, Jin-Yu, Ning, Daliang, Yu, Wen-Xing, Chen, Guan-Jun, Tao, Xuanyu, Zhou, Jizhong, Du, Zong-Jun, and Mu, Da-Shuai
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Humans ,Phylogeny ,Bacteria ,Microbiota ,Bacteroidetes ,Geologic Sediments ,Sulfates ,sulfate-reducing bacteria ,biotic interactions ,molecular ecological networks ,microbial community assembly ,organic matter degradation ,sulfate-reducing organisms ,Microbiology - Abstract
Sulfate-reducing bacteria (SRB) are essential functional microbial taxa for degrading organic matter (OM) in anoxic marine environments. However, there are little experimental data regarding how SRB regulates microbial communities. Here, we applied a top-down microbial community management approach by inhibiting SRB to elucidate their contributions to the microbial community during OM degradation. Based on the highly replicated microcosms (n = 20) of five different incubation stages, we found that many microbial community properties were influenced after inhibiting SRB, including the composition, structure, network, and community assembly processes. We also found a strong coexistence pattern between SRB and other abundant phylogenetic lineages via positive frequency-dependent selection. The relative abundances of the families Synergistaceae, Peptostreptococcaceae, Dethiosulfatibacteraceae, Prolixibacteraceae, Marinilabiliaceae, and Marinifilaceae were simultaneously suppressed after inhibiting SRB during OM degradation. A close association between SRB and the order Marinilabiliales among coexisting taxa was most prominent. They contributed to preserved modules during network successions, were keystone nodes mediating the networked community, and contributed to homogeneous ecological selection. The molybdate tolerance test of the isolated strains of Marinilabiliales showed that inhibited SRB (not the inhibitor of SRB itself) triggered a decrease in the relative abundance of Marinilabiliales. We also found that inhibiting SRB resulted in reduced pH, which is unsuitable for the growth of most Marinilabiliales strains, while the addition of pH buffer (HEPES) in SRB-inhibited treatment microcosms restored the pH and the relative abundances of these bacteria. These data supported that SRB could modify niches to affect species coexistence. IMPORTANCE Our model offers insight into the ecological properties of SRB and identifies a previously undocumented dimension of OM degradation. This targeted inhibition approach could provide a novel framework for illustrating how functional microbial taxa associate the composition and structure of the microbial community, molecular ecological network, and community assembly processes. These findings emphasize the importance of SRB during OM degradation. Our results proved the feasibility of the proposed study framework, inhibiting functional taxa at the community level, for illustrating when and to what extent functional taxa can contribute to ecosystem services.
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- 2023
22. Where is the field of autophagy research heading?
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Abeliovich, Hagai, Debnath, Jayanta, Ding, Wen-Xing, Jackson, William, Kim, Do-Hyung, Klionsky, Daniel, Ktistakis, Nicholas, Münz, Christian, Petersen, Morten, Sadoshima, Junichi, Vergne, Isabelle, and Margeta, Marta
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Ideas for your grant proposal ,suggestions ,the big picture ,the grand scheme ,thoughts ,yada yada yada ,Autophagy ,Biomedical Research - Abstract
In this editors corner, the section editors were asked to indicate where they see the autophagy field heading and to suggest what they consider to be key unanswered questions in their specialty area.
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- 2023
23. Security Monitoring System for Power IoTs Based on Machine Learning
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Huang, Zhenlin, primary, Wen, Xing, additional, Wang, Ning, additional, Zhao, Liuqi, additional, and Zhu, Jinwei, additional
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- 2024
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24. Global Priors Guided Modulation Network for Joint Super-Resolution and Inverse Tone-Mapping
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He, Gang, Long, Shaoyi, Xu, Li, Wu, Chang, Zhou, Jinjia, Sun, Ming, Wen, Xing, and Dai, Yurong
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Computer Science - Computer Vision and Pattern Recognition ,Electrical Engineering and Systems Science - Image and Video Processing - Abstract
Joint super-resolution and inverse tone-mapping (SR-ITM) aims to enhance the visual quality of videos that have quality deficiencies in resolution and dynamic range. This problem arises when using 4K high dynamic range (HDR) TVs to watch a low-resolution standard dynamic range (LR SDR) video. Previous methods that rely on learning local information typically cannot do well in preserving color conformity and long-range structural similarity, resulting in unnatural color transition and texture artifacts. In order to tackle these challenges, we propose a global priors guided modulation network (GPGMNet) for joint SR-ITM. In particular, we design a global priors extraction module (GPEM) to extract color conformity prior and structural similarity prior that are beneficial for ITM and SR tasks, respectively. To further exploit the global priors and preserve spatial information, we devise multiple global priors guided spatial-wise modulation blocks (GSMBs) with a few parameters for intermediate feature modulation, in which the modulation parameters are generated by the shared global priors and the spatial features map from the spatial pyramid convolution block (SPCB). With these elaborate designs, the GPGMNet can achieve higher visual quality with lower computational complexity. Extensive experiments demonstrate that our proposed GPGMNet is superior to the state-of-the-art methods. Specifically, our proposed model exceeds the state-of-the-art by 0.64 dB in PSNR, with 69$\%$ fewer parameters and 3.1$\times$ speedup. The code will be released soon., Comment: 10 pages, 7 figures
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- 2022
25. Recent insights about autophagy in pancreatitis
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Xiaowen Ma, Shaogui Wang, Wen-Xing Ding, Hong-Min Ni, and Sydney Kim
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Diseases of the digestive system. Gastroenterology ,RC799-869 - Abstract
Acute pancreatitis is a common inflammatory gastrointestinal disease without any successful treatment. Pancreatic exocrine acinar cells have high rates of protein synthesis to produce and secrete large amounts of digestive enzymes. When the regulation of organelle and protein homeostasis is disrupted, it can lead to endoplasmic reticulum (ER) stress, damage to the mitochondria and improper intracellular trypsinogen activation, ultimately resulting in acinar cell damage and the onset of pancreatitis. To balance the homeostasis of organelles and adapt to protect themselves from organelle stress, cells use protective mechanisms such as autophagy. In the mouse pancreas, defective basal autophagy disrupts ER homoeostasis, leading to ER stress and trypsinogen activation, resulting in spontaneous pancreatitis. In this review, we discuss the regulation of autophagy and its physiological role in maintaining acinar cell homeostasis and function. We also summarise the current understanding of the mechanisms and the role of defective autophagy at multiple stages in experimental pancreatitis induced by cerulein or alcohol.
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- 2024
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26. Two‐Dimensional Heterostructure Complementary Logic Enabled by Optical Writing
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Ayaz Ali, Matthias Schrade, Wen Xing, Per Erik Vullum, Ozhan Koybasi, Takashi Taniguchi, Kenji Watanabe, and Branson D. Belle
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2D materials ,complementary metal‐oxide semiconductor ,field effect transistors ,logic inverters ,Materials of engineering and construction. Mechanics of materials ,TA401-492 - Abstract
Integrated logic circuits using atomically thin, two‐dimensional (2D) materials offer several potential advantages compared to established silicon technologies such as increased transistor density, circuit complexity, and lower energy dissipation leading to scaling benefits. In this article, a novel approach to achieve tunable doping in 2D semiconductors is explored to achieve complementary transistors and logic integration. By selectively transferring WSe2 onto hBN and SiO2 substrates, complementary transistor behavior (n‐ and p‐type) was achieved using a UV light source and electrostatic activation. Furthermore, advanced characterization techniques, including high‐resolution transmission electron microscopy (HRTEM) and Kelvin probe force microscopy (KPFM), provided insights into the chemical composition and surface potential changes after UV writing. Finally, a logic inverter was successfully implemented using selectively photo‐induced doped WSe2 transistors, showcasing the potential for practical logic applications. This innovative method opens new avenues for designing energy‐efficient and reconfigurable 2D semiconductor circuits, addressing key challenges in modern electronics.
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- 2024
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27. A 65-dB SNDR Continuous-Time Delta-Sigma ADC Integrated by IZO Thin-Film Transistors.
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Wen-Xing Xu, Jun-Rong Chen, Fei-Fan Li, Lei Zhou, Xiao-Qin Wei, Miao Xu, Lei Wang, Wei-Jing Wu, Yu-Rong Liu, and Jun-Biao Peng
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- 2024
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28. Switched Fuzzy Control for Nonlinear Systems via a Fuzzy-Rule-Dependent Adaptive Event-Triggered Mechanism.
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Jing-Wen Xing, Chen Peng 0001, and Xiangpeng Xie 0001
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- 2024
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29. SDRTV-to-HDRTV via Hierarchical Dynamic Context Feature Mapping
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He, Gang, Xu, Kepeng, Xu, Li, Wu, Chang, Sun, Ming, Wen, Xing, and Tai, Yu-Wing
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Computer Science - Multimedia - Abstract
In this work, we address the task of SDR videos to HDR videos(SDRTV-to-HDRTV). Previous approaches use global feature modulation for SDRTV-to-HDRTV. Feature modulation scales and shifts the features in the original feature space, which has limited mapping capability. In addition, the global image mapping cannot restore detail in HDR frames due to the luminance differences in different regions of SDR frames. To resolve the appeal, we propose a two-stage solution. The first stage is a hierarchical Dynamic Context feature mapping (HDCFM) model. HDCFM learns the SDR frame to HDR frame mapping function via hierarchical feature modulation (HME and HM ) module and a dynamic context feature transformation (DCT) module. The HME estimates the feature modulation vector, HM is capable of hierarchical feature modulation, consisting of global feature modulation in series with local feature modulation, and is capable of adaptive mapping of local image features. The DCT module constructs a feature transformation module in conjunction with the context, which is capable of adaptively generating a feature transformation matrix for feature mapping. Compared with simple feature scaling and shifting, the DCT module can map features into a new feature space and thus has a more excellent feature mapping capability. In the second stage, we introduce a patch discriminator-based context generation model PDCG to obtain subjective quality enhancement of over-exposed regions. PDCG can solve the problem that the model is challenging to train due to the proportion of overexposed regions of the image. The proposed method can achieve state-of-the-art objective and subjective quality results. Specifically, HDCFM achieves a PSNR gain of 0.81 dB at a parameter of about 100K. The number of parameters is 1/14th of the previous state-of-the-art methods. The test code will be released soon., Comment: 9 pages
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- 2022
30. Luminance-Guided Chrominance Image Enhancement for HEVC Intra Coding
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Liu, Hewei, Yang, Renwei, Zhu, Shuyuan, Wen, Xing, and Zeng, Bing
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Computer Science - Computer Vision and Pattern Recognition ,Electrical Engineering and Systems Science - Image and Video Processing - Abstract
In this paper, we propose a luminance-guided chrominance image enhancement convolutional neural network for HEVC intra coding. Specifically, we firstly develop a gated recursive asymmetric-convolution block to restore each degraded chrominance image, which generates an intermediate output. Then, guided by the luminance image, the quality of this intermediate output is further improved, which finally produces the high-quality chrominance image. When our proposed method is adopted in the compression of color images with HEVC intra coding, it achieves 28.96% and 16.74% BD-rate gains over HEVC for the U and V images, respectively, which accordingly demonstrate its superiority., Comment: ISCAS 2022
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- 2022
31. NTIRE 2022 Challenge on High Dynamic Range Imaging: Methods and Results
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Pérez-Pellitero, Eduardo, Catley-Chandar, Sibi, Shaw, Richard, Leonardis, Aleš, Timofte, Radu, Zhang, Zexin, Liu, Cen, Peng, Yunbo, Lin, Yue, Yu, Gaocheng, Zhang, Jin, Ma, Zhe, Wang, Hongbin, Chen, Xiangyu, Wang, Xintao, Wu, Haiwei, Liu, Lin, Dong, Chao, Zhou, Jiantao, Yan, Qingsen, Zhang, Song, Chen, Weiye, Liu, Yuhang, Zhang, Zhen, Zhang, Yanning, Shi, Javen Qinfeng, Gong, Dong, Zhu, Dan, Sun, Mengdi, Chen, Guannan, Hu, Yang, Li, Haowei, Zou, Baozhu, Liu, Zhen, Lin, Wenjie, Jiang, Ting, Jiang, Chengzhi, Li, Xinpeng, Han, Mingyan, Fan, Haoqiang, Sun, Jian, Liu, Shuaicheng, Marín-Vega, Juan, Sloth, Michael, Schneider-Kamp, Peter, Röttger, Richard, Li, Chunyang, Bao, Long, He, Gang, Xu, Ziyao, Xu, Li, Zhan, Gen, Sun, Ming, Wen, Xing, Li, Junlin, Li, Jinjing, Li, Chenghua, Gang, Ruipeng, Li, Fangya, Liu, Chenming, Feng, Shuang, Lei, Fei, Liu, Rui, Ruan, Junxiang, Dai, Tianhong, Li, Wei, Lu, Zhan, Liu, Hengyan, Huang, Peian, Ren, Guangyu, Luo, Yonglin, Liu, Chang, Tu, Qiang, Ma, Sai, Cao, Yizhen, Tel, Steven, Heyrman, Barthelemy, Ginhac, Dominique, Lee, Chul, Kim, Gahyeon, Park, Seonghyun, Vien, An Gia, Mai, Truong Thanh Nhat, Yoon, Howoon, Vo, Tu, Holston, Alexander, Zaheer, Sheir, and Park, Chan Y.
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Computer Science - Computer Vision and Pattern Recognition ,Electrical Engineering and Systems Science - Image and Video Processing - Abstract
This paper reviews the challenge on constrained high dynamic range (HDR) imaging that was part of the New Trends in Image Restoration and Enhancement (NTIRE) workshop, held in conjunction with CVPR 2022. This manuscript focuses on the competition set-up, datasets, the proposed methods and their results. The challenge aims at estimating an HDR image from multiple respective low dynamic range (LDR) observations, which might suffer from under- or over-exposed regions and different sources of noise. The challenge is composed of two tracks with an emphasis on fidelity and complexity constraints: In Track 1, participants are asked to optimize objective fidelity scores while imposing a low-complexity constraint (i.e. solutions can not exceed a given number of operations). In Track 2, participants are asked to minimize the complexity of their solutions while imposing a constraint on fidelity scores (i.e. solutions are required to obtain a higher fidelity score than the prescribed baseline). Both tracks use the same data and metrics: Fidelity is measured by means of PSNR with respect to a ground-truth HDR image (computed both directly and with a canonical tonemapping operation), while complexity metrics include the number of Multiply-Accumulate (MAC) operations and runtime (in seconds)., Comment: CVPR Workshops 2022. 15 pages, 21 figures, 2 tables
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- 2022
32. Glutamine synthetase limits b-catenin-mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1
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Dai, Weiwei, Shen, Jianliang, Yan, Junrong, Bott, Alex J, Maimouni, Sara, Daguplo, Heineken Q, Wang, Yujue, Khayati, Khoosheh, Guo, Jessie Yanxiang, Zhang, Lanjing, Wang, Yongbo, Valvezan, Alexander, Ding, Wen-Xing, Chen, Xin, Su, Xiaoyang, Gao, Shenglan, and Zong, Wei-Xing
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Biochemistry and Cell Biology ,Biomedical and Clinical Sciences ,Oncology and Carcinogenesis ,Biological Sciences ,Cancer ,Digestive Diseases ,Liver Disease ,Rare Diseases ,Animals ,Mice ,Glutamate-Ammonia Ligase ,beta Catenin ,Mechanistic Target of Rapamycin Complex 1 ,Ammonia ,Nitrogen ,Liver Neoplasms ,Liver ,Glutamine ,Homeostasis ,Urea ,Hepatology ,Liver cancer ,Metabolism ,Medical and Health Sciences ,Immunology ,Biological sciences ,Biomedical and clinical sciences ,Health sciences - Abstract
Glutamine synthetase (GS) catalyzes de novo synthesis of glutamine that facilitates cancer cell growth. In the liver, GS functions next to the urea cycle to remove ammonia waste. As a dysregulated urea cycle is implicated in cancer development, the impact of GS's ammonia clearance function has not been explored in cancer. Here, we show that oncogenic activation of β-catenin (encoded by CTNNB1) led to a decreased urea cycle and elevated ammonia waste burden. While β-catenin induced the expression of GS, which is thought to be cancer promoting, surprisingly, genetic ablation of hepatic GS accelerated the onset of liver tumors in several mouse models that involved β-catenin activation. Mechanistically, GS ablation exacerbated hyperammonemia and facilitated the production of glutamate-derived nonessential amino acids, which subsequently stimulated mechanistic target of rapamycin complex 1 (mTORC1). Pharmacological and genetic inhibition of mTORC1 and glutamic transaminases suppressed tumorigenesis facilitated by GS ablation. While patients with hepatocellular carcinoma, especially those with CTNNB1 mutations, have an overall defective urea cycle and increased expression of GS, there exists a subset of patients with low GS expression that is associated with mTORC1 hyperactivation. Therefore, GS-mediated ammonia clearance serves as a tumor-suppressing mechanism in livers that harbor β-catenin activation mutations and a compromised urea cycle.
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- 2022
33. Large yellow croaker (Larimichthys crocea) mitofusin 2 inhibits type I IFN responses by degrading MAVS via enhanced K48-linked ubiquitination
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Li, Wen-Xing, Wang, Xiao-Hong, Lin, Yi-Jun, Zhou, Yuan-Yuan, Li, Jun, Zhang, Xiang-Yang, and Chen, Xin-Hua
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- 2023
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34. GRP78 protein metabolism in obese and diabetic rats: a study of its role in metabolic disorders
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Kai Xi, Hua-Ping Li, Yue-Hui Wang, Yang-Yang Li, Lei Wang, Miao-Miao Zhang, Xi Zhang, and Bing-Wen Xing
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Auditory brainstem response ,Cochlea histology ,Diabetic rat ,Endoplasmic reticulum stress ,Obese rat ,Nutritional diseases. Deficiency diseases ,RC620-627 - Abstract
Abstract Objective This study aimed to compare and analyze the expression and significance of the GRP78 protein in cochlear cell injury induced by a high glucose and high-fat diet in obese and diabetic rats. Methods Male SD rats were randomly divided into two groups: normal (NC) and high-fat (HF) groups. The NC group was fed a standard diet for eight weeks, while the HF group received a high-glucose, high-fat diet. The HF group was further categorized into the obesity group (OB group) and the type II diabetes mellitus group (T2DM group). To induce a type II diabetes mellitus (T2DM) model, the T2DM group received an intraperitoneal injection of a small dose of STZ (45 mg/kg). After four weeks on the original diet, body weight, blood glucose, blood lipid levels, and auditory brainstem response (ABR) thresholds were measured. The cochlea was dissected, and its morphology was observed using HE staining. Immunohistochemistry and western blotting were utilized to examine the expression level of the GRP78 protein in the cochlea. Results (1) The ABR threshold demonstrated a statistically significant difference between the T2DM group and the OB group (P
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- 2024
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35. High-throughput screening of novel TFEB agonists in protecting against acetaminophen-induced liver injury in mice
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Xiaojuan Chao, Mengwei Niu, Shaogui Wang, Xiaowen Ma, Xiao Yang, Hua Sun, Xujia Hu, Hua Wang, Li Zhang, Ruili Huang, Menghang Xia, Andrea Ballabio, Hartmut Jaeschke, Hong-Min Ni, and Wen-Xing Ding
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Autophagy ,DILI ,Drug screening ,Hepatotoxicity ,Lysosome ,Mitochondria ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Macroautophagy (referred to as autophagy hereafter) is a major intracellular lysosomal degradation pathway that is responsible for the degradation of misfolded/damaged proteins and organelles. Previous studies showed that autophagy protects against acetaminophen (APAP)-induced injury (AILI) via selective removal of damaged mitochondria and APAP protein adducts. The lysosome is a critical organelle sitting at the end stage of autophagy for autophagic degradation via fusion with autophagosomes. In the present study, we showed that transcription factor EB (TFEB), a master transcription factor for lysosomal biogenesis, was impaired by APAP resulting in decreased lysosomal biogenesis in mouse livers. Genetic loss-of and gain-of function of hepatic TFEB exacerbated or protected against AILI, respectively. Mechanistically, overexpression of TFEB increased clearance of APAP protein adducts and mitochondria biogenesis as well as SQSTM1/p62-dependent non-canonical nuclear factor erythroid 2-related factor 2 (NRF2) activation to protect against AILI. We also performed an unbiased cell-based imaging high-throughput chemical screening on TFEB and identified a group of TFEB agonists. Among these agonists, salinomycin, an anticoccidial and antibacterial agent, activated TFEB and protected against AILI in mice. In conclusion, genetic and pharmacological activating TFEB may be a promising approach for protecting against AILI.
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- 2024
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36. TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis
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Matye, David, Gunewardena, Sumedha, Chen, Jianglei, Wang, Huaiwen, Wang, Yifeng, Hasan, Mohammad Nazmul, Gu, Lijie, Clayton, Yung Dai, Du, Yanhong, Chen, Cheng, Friedman, Jacob E, Lu, Shelly C, Ding, Wen-Xing, and Li, Tiangang
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Biochemistry and Cell Biology ,Biomedical and Clinical Sciences ,Biological Sciences ,Digestive Diseases ,Liver Disease ,Chronic Liver Disease and Cirrhosis ,Complementary and Integrative Health ,Genetics ,Nutrition ,Oral and gastrointestinal ,Metabolic and endocrine ,Zero Hunger ,Amino Acids ,Sulfur ,Animals ,Antioxidants ,Basic Helix-Loop-Helix Leucine Zipper Transcription Factors ,Coenzyme A ,Cysteine ,Cystine ,Dietary Proteins ,Fatty Liver ,Glutathione ,Homeostasis ,Lipids ,Liver ,Methionine ,Methionine Adenosyltransferase ,Mice ,Oxidation-Reduction - Abstract
Fatty liver is a highly heterogenous condition driven by various pathogenic factors in addition to the severity of steatosis. Protein insufficiency has been causally linked to fatty liver with incompletely defined mechanisms. Here we report that fatty liver is a sulfur amino acid insufficient state that promotes metabolic inflexibility via limiting coenzyme A availability. We demonstrate that the nutrient-sensing transcriptional factor EB synergistically stimulates lysosome proteolysis and methionine adenosyltransferase to increase cysteine pool that drives the production of coenzyme A and glutathione, which support metabolic adaptation and antioxidant defense during increased lipid influx. Intriguingly, mice consuming an isocaloric protein-deficient Western diet exhibit selective hepatic cysteine, coenzyme A and glutathione deficiency and acylcarnitine accumulation, which are reversed by cystine supplementation without normalizing dietary protein intake. These findings support a pathogenic link of dysregulated sulfur amino acid metabolism to metabolic inflexibility that underlies both overnutrition and protein malnutrition-associated fatty liver development.
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- 2022
37. The role of physical activity on healthcare utilization in China
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Lei, Xiao-Lin, Gao, Ke, Wang, Huan, Chen, Wei, Chen, Gen-Rui, and Wen, Xing
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- 2023
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38. Machine learning for differentiation of lipid-poor adrenal adenoma and subclinical pheochromocytoma based on multiphase CT imaging radiomics
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Xiao, Dao-xiong, Zhong, Jian-ping, Peng, Ji-dong, Fan, Cun-geng, Wang, Xiao-chun, Wen, Xing-lin, Liao, Wei-wei, Wang, Jun, and Yin, Xiao-feng
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- 2023
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39. Cytoplasmic Endonuclease G promotes nonalcoholic fatty liver disease via mTORC2-AKT-ACLY and endoplasmic reticulum stress
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Wang, Wenjun, Tan, Junyang, Liu, Xiaomin, Guo, Wenqi, Li, Mengmeng, Liu, Xinjie, Liu, Yanyan, Dai, Wenyu, Hu, Liubing, Wang, Yimin, Lu, Qiuxia, Lee, Wen Xing, Tang, Hong-Wen, and Zhou, Qinghua
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- 2023
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40. Thermochemical oxidation of methane by manganese oxides in hydrothermal sediments
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Huang, Qin, Jiang, Shao-Yong, Pi, Dao-Hui, Konhauser, Kurt O., Wen, Xing-Ping, Lu, Liu-Yi, and Yan, Hao
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- 2023
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41. Atomically Dispersed Dual-Metal Sites Showing Unique Reactivity and Dynamism for Electrocatalysis
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Wu, Jun-Xi, Chen, Wen-Xing, He, Chun-Ting, Zheng, Kai, Zhuo, Lin-Ling, Zhao, Zhen-Hua, and Zhang, Jie-Peng
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- 2023
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42. Next-generation large-scale binary protein interaction network for Drosophila melanogaster
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Tang, Hong-Wen, Spirohn, Kerstin, Hu, Yanhui, Hao, Tong, Kovács, István A., Gao, Yue, Binari, Richard, Yang-Zhou, Donghui, Wan, Kenneth H., Bader, Joel S., Balcha, Dawit, Bian, Wenting, Booth, Benjamin W., Coté, Atina G., de Rouck, Steffi, Desbuleux, Alice, Goh, Kah Yong, Kim, Dae-Kyum, Knapp, Jennifer J., Lee, Wen Xing, Lemmens, Irma, Li, Cathleen, Li, Mian, Li, Roujia, Lim, Hyobin Julianne, Liu, Yifang, Luck, Katja, Markey, Dylan, Pollis, Carl, Rangarajan, Sudharshan, Rodiger, Jonathan, Schlabach, Sadie, Shen, Yun, Sheykhkarimli, Dayag, TeeKing, Bridget, Roth, Frederick P., Tavernier, Jan, Calderwood, Michael A., Hill, David E., Celniker, Susan E., Vidal, Marc, Perrimon, Norbert, and Mohr, Stephanie E.
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- 2023
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43. Clinical characteristics of patients with prenatal hydronephrosis in early postnatal period: a single center retrospective study
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Gu, Song-Lei, Yang, Xiao-Qing, Zhai, Yi-Hui, Xu, Wen-Li, Guo, Wen-Xing, and Shen, Tong
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- 2023
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44. Design of silicon-based micro-actuator with two state-recoverable semicircle slides for switching on/off detonation energy
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Wei Liu, Wen-xing Kan, Pei Fu, Teng-jiang Hu, Wei Ren, En-yi Chu, Yu-long Zhao, Rui-zhen Xie, Xiao-ming Ren, and Lan Liu
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Physics ,QC1-999 - Abstract
The micro-actuator is a key element of the MEMS-based initiator. In order to ensure safety and achieve the function of detonation energy isolation and transmission of the micro-pyrotechnic sequence, it is necessary to set up a safety and arming device between the micro-heater and energetic materials on the next level in the initiator. In this paper, the MEMS safety and arming device was simulated and analyzed, and the actuator chip was made based on MEMS technology and then tested. The results showed that the maximum temperature and displacement generated by the silicon-based micro-actuator increased with increasing actuation voltage. When the actuation voltage was larger than 16 V, the device could not work normally because the maximum temperature of the device was higher than the melting point of silicon. Furthermore, the influence factors on the state-recoverable property of the device were studied by changing the actuation voltage, length, width, and thickness of the V-shaped beam in a single way. The results showed that when the actuation voltage remained unchanged and the other factors were changed in a single way, the smaller structural parameters resulted in the shorter response time and recovery time, while the displacement generated was smaller. Meanwhile, the larger structural parameters resulted in larger displacements, while the response time and recovery time were larger. In addition, the state-recoverable characteristics of the device were affected by the working environmental temperature. It is of great significance to the design of the MEMS-based initiator.
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- 2024
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45. Characteristics and mechanism of winter marine heatwaves in the cold tongue region of the South China Sea
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Linxi Meng, Yunwei Yan, Lei Zhang, Wen Xing, Yi Yu, and Xiaogang Xing
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marine heatwaves ,South China Sea ,cold tongue ,statistical characteristics ,mixed layer heat budget ,Science ,General. Including nature conservation, geographical distribution ,QH1-199.5 - Abstract
Marine Heatwaves (MHWs) are persistent anomalous sea surface temperature warming events that can affect the marine ecological environment and ecosystems. Here, we study the winter MHWs in the cold tongue region of the South China Sea (SCS) from 1982 to 2022. Our results show that the winter MHWs in the cold tongue region have the strongest cumulative intensity in the SCS, exceeding 45°C·day/time. These strong MHWs are due to their high mean intensity and long duration. Significant interannual variations are observed in these MHWs, with extreme MHW events occurring in the El Niño winters of 97/98 and 15/16. By employing a mixed layer heat budget analysis, we reveal that the extreme MHW event in the winter of 97/98 is caused primarily by the surface heat flux term, and secondarily by the vertical entrainment term. While the 15/16 extreme event is caused by a combination of the surface heat flux term, the vertical entrainment term and the horizontal advection term.
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- 2024
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46. Long-term trends and extreme events of marine heatwaves in the Eastern China Marginal Seas during summer
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Jing Xu, Yunwei Yan, Lei Zhang, Wen Xing, Linxi Meng, Yi Yu, and Changlin Chen
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marine heatwaves (MHWs) ,long-term trends ,extreme events ,Eastern China Marginal Seas (ECMS) ,sea surface temperature (SST) ,Science ,General. Including nature conservation, geographical distribution ,QH1-199.5 - Abstract
Marine heatwaves (MHWs) are a type of widespread, persistent, and extreme marine warming event that can cause serious harm to the global marine ecology and economy. This study provides a systematic analysis of the long-term trends of MHWs in the Eastern China Marginal Seas (ECMS) during summer spanning from 1982 to 2022, and occurrence mechanisms of extreme MHW events. The findings show that in the context of global warming, the frequency of summer MHWs in the ECMS has increased across most regions, with a higher rate along the coast of China. Areas exhibiting a rapid surge in duration predominantly reside in the southern Yellow Sea (SYS) and southern East China Sea (ECS, south of 28°N). In contrast, the long-term trends of mean and maximum intensities exhibit both increases and decreases: Rising trends primarily occur in the Bohai Sea (BS) and Yellow Sea (YS), whereas descending trends are detected in the northern ECS (north of 28°N). Influenced jointly by duration and mean intensity, cumulative intensity (CumInt) exhibits a notable positive growth off the Yangtze River Estuary, in the SYS and southern ECS. By employing the empirical orthogonal function, the spatio-temporal features of the first two modes of CumInt and their correlation with summer mean sea surface temperature (SST) and SST variance are further examined. The first mode of CumInt displays a positive anomalous pattern throughout the ECMS, with notable upward trend in the corresponding time series, and the rising trend is primarily influenced by summer mean SST warming. Moreover, both of the first two modes show notable interannual variability. Extreme MHW events in the SYS in 2016 and 2018 are examined using the mixed layer temperature equation. The results suggest that these extreme MHW events originate primarily from anomalous atmospheric forcing and oceanic vertical mixing. These processes involve an anomalous high-pressure system over the SYS splitting from the western Pacific subtropical high, augmented atmospheric stability, diminished wind speeds, intensified solar radiation, and reduced oceanic mixing, thereby leading to the accumulation of more heat near the sea surface and forming extreme MHW events.
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- 2024
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47. Perspectives of mitochondria-lysosome-related organelle in hepatocyte dedifferentiation and implications in chronic liver disease
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Xiaowen Ma, Wen-Xing Ding, and Hong-Min Ni
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Diseases of the digestive system. Gastroenterology ,RC799-869 - Published
- 2024
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48. Soil enzyme profile analysis for indicating decomposer micro‐food web
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Wen Xing, Ning Hu, Zhongfang Li, Liangshan Feng, Weidong Zhang, Gerhard Du Preez, Huimin Zhang, Dongchu Li, Shunbao Lu, Scott X. Chang, Qingwen Zhang, and Yilai Lou
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co‐occurrence network ,decomposition channel ,food web ,microbiome ,nematode ,protozoa ,Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
Abstract Highly diverse exoenzymes mediate the energy flow from substrates to the multitrophic microbiota within the soil decomposer micro‐food web. Here, we used a “soil enzyme profile analysis” approach to establish a series of enzyme profile indices; those indices were hypothesized to reflect micro‐food web features. We systematically evaluated the shifts in enzyme profile indices in relation to the micro‐food web features in the restoration of an abandoned cropland to a natural area. We found that enzymatic C:N stoichiometry and decomposability index were significantly associated with substrate availability. Furthermore, the higher Shannon diversity index in the exoenzyme profile, especially for the C‐degrading hydrolase, corresponded to a greater microbiota community diversity. The increased complexity and stability of the exoenzyme network reflected similar changes with the micro‐food web networks. In addition, the gross activity of the enzyme profile as a parameter for soil multifunctionality, effectively predicted the substrate content, microbiota community size, diversity, and network complexity. Ultimately, the proposed enzymic channel index was closely associated with the traditional decomposition channel indices derived from microorganisms and nematodes. Our results showed that soil enzyme profile analysis reflected very well the decomposer food web features. Our study has important implications for projecting future climate change or anthropogenic disturbance impacts on soil decomposer micro‐food web features by using soil enzyme profile analysis.
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- 2024
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49. The In-Flight Realtime Trigger and Localization Software of GECAM
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Zhao, Xiao-Yun, Xiong, Shao-Lin, Wen, Xiang-Yang, Li, Xin-Qiao, Cai, Ce, Xiao, Shuo, Luo, Qi, Peng, Wen-Xi, Guo, Dong-Ya, An, Zheng-Hua, Gong, Ke, Liao, Jin-Yuan, Zhang, Yan-Qiu, Huang, Yue, Li, Lu, Wen, Xing, Zhang, Fei, Duan, Jing, Wang, Chen-Wei, Shi, Dong-Li, Zhang, Peng, Yi, Qi-Bin, Li, Chao-Yang, Xu, Yan-Bing, Liang, Xiao-Hua, Liu, Ya-Qing, Zhang, Da-Li, Sun, Xi-Lei, Zhang, Fan, Chen, Gang, Wang, Huan-Yu, Yang, Sheng, Liu, Xiao-Jing, Gao, Min, Li, Mao-Shun, Wang, Jin-Zhou, Zhou, Xing, Zhao, Yi, Xue, Wang-Chen, Zheng, Chao, Liu, Jia-Cong, Han, Xing-Bo, Qi, Jin-Ling, Huang, Jia, Zhang, Ke-Ke, Chen, Can, Yang, Xiong-Tao, Hou, Dong-Jie, Wang, Yu-Sa, Qiao, Rui, Ma, Xiang, Li, Xiao-Bo, Wang, Ping, Song, Xin-Ying, Song, Li-Ming, Zheng, Shi-Jie, Li, Bing, Zhang, Hong-Mei, Zhu, Yue, Chen, Wei, He, Jian-Jian, Zhang, Zhen, Hou, Jin, Wang, Hong-Jun, Hao, Yan-Chao, Wang, Xiang-Yu, Yang, Zong-Yuan, Wen, Zhi-Long, Chang, Zhi, Du, Yuan-Yuan, Gao, Rui, Lan, Xiao-Fei, Li, Yan-Guo, Li, Gang, Li, Xu-Fang, Lu, Fang-Jun, Lu, Hong, Meng, Bin, Shi, Feng, Wang, Hui, Wang, Hui-Zhen, Xu, Yu-Peng, Yang, Jia-Wei, Yang, Xue-Juan, Zhang, Shuang-Nan, Zhang, Chao-Yue, Zhang, Cheng-Mo, Tang, Zhi-Cheng, and Cheng, Cheng
- Subjects
Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
Realtime trigger and localization of bursts are the key functions of GECAM, which is an all-sky gamma-ray monitor launched in Dec 10, 2020. We developed a multifunctional trigger and localization software operating on the CPU of the GECAM electronic box (EBOX). This onboard software has the following features: high trigger efficiency for real celestial bursts with a suppression of false triggers caused by charged particle bursts and background fluctuation, dedicated localization algorithm optimized for short and long bursts respetively, short time latency of the trigger information which is downlinked throught the BeiDou satellite navigation System (BDS). This paper presents the detailed design and deveopment of this trigger and localization software system of GECAM, including the main functions, general design, workflow and algorithms, as well as the verification and demonstration of this software, including the on-ground trigger tests with simulated gamma-ray bursts made by a dedicated X-ray tube and the in-flight performance to real gamma-ray bursts and magnetar bursts., Comment: Draft, comments welcome
- Published
- 2021
50. Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression
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Qian, Qingwen, Li, Mark, Zhang, Zeyuan, Davis, Shannon W., Rahmouni, Kamal, Norris, Andrew W., Cao, Huojun, Ding, Wen-Xing, Hotamisligil, Gökhan S., and Yang, Ling
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- 2024
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