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Herein, we report the preparation and characterisation of fluororubber coated superhydrophobic Poly (ethylene tetrapthalate) (PET) fabric and polyurethane (PU) sponge. The coating surface structure...

A direct selective approach to the oxidation of sulfides to sulfoxides and sulfones with H2O2 in moderate to good yields is developed. The reaction proceeds in the presence of 2 mol % of VO(acac)2 at room temperature. All sulfoxides and sulfones were detected by gas chromatography, and the molecular structures of 2-methylbenzyl 4-methylphenyl sulfone, 4-methylbenzyl 4-methylphenyl sulfone, 2-bromobenzyl 4-methylphenyl sulfone, and 4-tert-butylbenzyl benzyl sulfone were determined by single crystal X-ray crystallography.

Self-assembly of cis-[RuCl2(dmso)4], NaVO3, Na2MoO4 and NaH2PO4 in a molar ratio of 1 : 3 : 6 : 1 in HOAc–NaOAc buffer (pH = 4–5) in the presence of CsCl gave a ruthenium(II)-supported phosphovanadomolybdate [RuII(dmso)3PMoVI6VV3O32]6− (1). While a similar reaction with the reactants in a molar ratio of 1 : 6 : 12 : 2 afforded a ruthenium substituted “sandwich” type polyoxometalate [RuII(PMoVI6VV3O32)2]14− (2). Clusters 1 and 2 were well characterized by single-crystal X-ray diffraction. Their use as heterogeneous catalysts for oxidation of alcohols in the presence of molecular oxygen was also investigated.

Twenty-four aryl benzyl sulfides, diaryl sulfides and dibenzyl sulfides were synthesized by four methods and characterized by 1H NMR, FT-IR and Gas chromatography. The reaction conditions of different synthesis methods were studied from the aspects of time, solvent, base and dispersant. The molecular structures of benzylphenyl sulfide (2S), (4-tert-butylbenzyl)(4-methylphenyl) sulfide (4S), (4-methylbenzyl)(4-methylphenyl) sulfide (9S), di(4-methylphenyl) sulfide (11S), (3,5-dimethylphenyl)(4-methyl phenyl) sulfide (15S), and dibenzyl sulfide (19S) [22] have been determined by single-crystal X-ray crystallography. Compounds 2S and 15S crystallize in the monoclinic space group P21/c, with a = 12.278(3), b = 15.894(3), c = 5.6056(11) A, β = 94.532(2)°, and Z = 4 for 2S, and a = 9.800(9), b = 7.950(7), c = 16.690(15) A, β = 100.890(12)°, and Z = 4 for 15S. The unit cell of 4S has a triclinic Pī symmetry with the cell parameters a = 6.0436(10), b = 8.7871(14), c = 15.535(2) A, α = 81.921(2)°, β = 81.977(2)°, γ = 80.889(2)°, and Z = 2. Compounds 9S and 11S both crystallize in the orthorhombic space group P212121, with a = 6.188(3), b = 8.041(4), c = 26.005(14) A, and Z = 4 for 9S, and a = 5.835(2), b = 8.010(3), c = 25.131(9) A, and Z = 4 for 11S. Twenty-four aryl sulfide compounds with different substituents were synthesized and characterized, and the molecular structures of six different sulfide compounds have been determined by single-crystal X-ray crystallography.

Condensation of ferrocenoylacetone with arylamine or benzylamine in toluene at reflux afforded a series of N,O-bidentate ferrocenoyl enaminone ligands, Fc–C(O)CH = C(CH3)N(H)R1 (HL1: R1 = C6H5; HL2: R1 = 4-I-C6H4; HL3: R1 = 4-Cl-C6H4; HL4: R1 = 4-Me-C6H4; HL5: R1 = 4-OMe-C6H4; HL6: R1 = 2-Me-C6H4; HL7: R1 = 2-OMe-C6H4; HL8: R1 = 2-F-C6H4; HL9: R1 = CH2C6H5; Fc = ferrocenyl). Reaction of Cu(CH3COO)2 with two equivalents of HL1, HL3, and HL5-HL8 in the presence of CH3ONa in ethanol gave six copper complexes, [Cu(L1)2] (1), [Cu(L3)2] (2), [Cu(L5)2] (3), [Cu(L6)2] (4), [Cu(L7)2] (5) and [Cu(L8)2] (6), respectively. All compounds were characterized by 1H NMR, FT-IR, and UV–vis spectroscopies along with their electrochemical properties. The molecular structures of HL1-HL3, HL5, HL6, and HL8, together with the copper complexes 2.0.6C2H5OH and 3.CH3OH have been established by single-crystal X-ray diffraction.

By preparing 15 batches of lyophilized powder samples of substance benchmark in Houpo Wenzhong Decoction,the fingerprint,index component content and extract rate were determined,and the characteristic peaks,the range of similarity with the reference map,the content range and transfer rate range of magnolol,hesperidin,glycyrrhizic acid and pinocembrin,the extract rate range and the change range were clarified. The results showed that the similarity between the fingerprint of substance benchmark and the reference map R generated from the 15 batches of substance benchmark samples was higher than 0. 90. The assignment of the characteristic peaks in the full prescriptionapos;s fingerprint of the herbs except Poria cocos was clarified. Nineteen characteristic peaks were assigned,and 12 characteristic peaks were assigned by the reference substance,of which 4 were from Magnolia ocinalis Cortex,5 from Exocarpium Citri Rubrum,2 from Radix aucklandiae,3 from Glycyrrhiza Radix et Rhizoma,4 from Semen Alpiniae Katsumadai,and one from Rhizoma Zingiberis and Zingiber officinale Roscoe. The index component content range and transfer rate range were 0. 80%-1. 14% and 20. 25%-39. 61% for hesperidin,0. 49%-0. 79% and 23. 09%-33. 87%for glycyrrhizic acid,0. 03%-0. 07% and 3. 55%-10. 09% for pinocembrin,0. 15%-0. 38% and 8. 08%-24. 35% for magnolol. The extract rate range and the change range were22. 60%-25. 57% and 12. 67%-23. 68% respectively. In this study,we introduced the concepts of index component content,fingerprint,extract rate,explored the transfer relation of quality value transmitting of substance benchmark in Houpo Wenzhong Decoction,and initially established the quality standard of Houpo Wenzhong Decoction,all of which would provide ideas for the development and research of similar prescriptions.

Carbon/carbon–copper(C/C–Cu) composites are fabricated by infiltration of Cu into Mo2C interlayer-modified carbon/carbon(C/C) preforms. Effect of graphitization on the microstructure and properties of the C/C–Cu composites is studied. The C/C–Cu composite with graphitization shows lower electrical resistivity, thermal expansion coefficient, friction coefficient, and an obvious higher thermal conductivity due to higher graphitization degree. However, it presents lower flexural strength, impact toughness, and higher wear rate. The composite with graphitization exhibits mainly abrasive wear while that without graphitization exhibits mainly adhesion wear, and both composites show oxidation wear.

Carbon/carbon–copper(C/C-Cu) composites were fabricated by pressure-less infiltration of Cu into carbon/carbon (C/C) preforms modified with Mo2C interlayer by a molten salt method. Cu filled the pores inside the Mo2C-modified preforms fully, and retained an interconnected net-like distribution in the C/C-Cu composites. The electrical resistivity and flexural strength increased, whereas impact toughness decreased with the increase of preform density. Fiber pull-out and crack propagation along the interface contributed to the pseudo-plastic behavior of the composites. The tribological performance was improved with the increase of preform density due to the better lubrication of transfer films.

A carbon/carbon–ZrC(C/C–ZrC) composite was fabricated by reactive infiltration of a Zr–40 wt% Cu powder mixture. The C/C–ZrC composite was composed of C, ZrC, and residual Cu. Continuous ZrC layers around the pyrolytic carbon and isolated ZrC particles dispersed in Cu were detected. Linear ablation rate of the composite increased with the increase of ablation time. Ablation surface of the composite was mainly composed of monoclinic ZrO2, while the quantity of Cu and Cu2O decreased with the increase of ablation time. The better ablation resistance of the C/C–ZrC composite was mainly attributed to the protective ZrO2 layer and the cooling effect of Cu.

In this paper, a Bose-Hubbard extension of a Weyl semimetal is proposed that can be realized for ultracold atoms using laser assisted tunneling and Feshbach resonance technique in three dimensional optical lattices. The global phase diagram is obtained consisting of a superfluid phase and various Mott insulator phases by using Landau theory. The Bogoliubov excitation modes for the weakly interacting case have nontrivial properties (Weyl nodes, bosonic surface arc, etc.) analogs of those in Weyl semimetals of electronic systems, which are smoothly carried over to that of Bloch bands for the noninteracting case. The properties of the insulating phases for the strongly interacting case are explored by calculating both the quasiparticle and quasihole dispersion relation, which shows two quasiparticle spectra touch at Weyl nodes.

To evaluate the feasibility of and indication for laparoscopic methods for neonates with congenital duodenal obstruction.From September 2009 to October 2012, 40 newborns with duodenal obstruction underwent exploratory laparoscopy. With a lower-pressure pneumoperitoneum of 6-8 mm Hg and a suspending suture for the right liver elevator, the procedure was performed using four trocars 3-5 mm in diameter. Under laparoscopic vision, the causes of duodenal obstruction were diagnosed, and then the operation methods were determined by the type of obstruction.Of the 40 cases, 4 were duodenal atresia (type II), 8 were duodenal stenosis, 8 were annular pancreas, and 20 were congenital intestinal malrotation. For the cases with duodenal diaphragmatic stenosis a partial excision of the diaphragm was performed after longitudinal incision of the anterior part of the duodenum followed laparoscopically by a transverse suture. For the cases with duodenal atresia (type II) and annular pancreas, a duodenal diamond anastomosis was successfully carried out through a laparoscopic approach. Ladd's operational method was performed in the cases with congenital intestinal malrotation. Feedings were started on postoperative Day 3-7, without abdominal distention and vomiting, and discharge from the the hospital was on postoperative Day 9-14.Congenital duodenal obstruction is a common malformation in neonates. The laparoscopic procedure is an important method of diagnosing, and correct operational methods are the key to improve the therapeutic effect in the treatment of congenital duodenal obstruction. The laparoscope has the value of a small incision, microinvasion, and better recovery in diagnosis and treatment for congenital duodenal obstruction. The laparoscopic methods can be performed in neonates safely and are appropriate for a full-term newborn with tolerance to CO2 pneumoperitoneum.

To observe the effects of Danshen aqueous extract (DSAE) on the cerebral tissue and nerve stem cells in cerebral ischemia reperfusion (CIR) rats. The model rats were prepared by occlusion of the middle cerebral artery for 2 h and then by reperfusion. They were randomly divided into five groups: a control group, an CIR group and three DSAE-treated groups. As compared with the sham control group, there was significant increase (P < 0.05, P < 0.01) in the serum high-sensitivity C-reactive protein (hs-CRP) and interleukin-8 (IL-8) levels, interleukin-10 (IL-10), tumor necrosis factor-alpha (TNF-α) levels, and IL-10 mRNA, TNF-α mRNA expression levels, function score, Infarct size, TUNEL + cell counts, cerebral transforming growth factor beta 1 (TGF-β1) positive expression and cerebral neuron specific enolase (NSE) levels, and decrease in fas-associated protein with death domain (FADD) and death-associated protein (Daxx) positive expression levels in the CIR group. Compared with CIR group, DSAE treatment dose-dependently significantly decreased serum hs-CRP, IL-8, IL-10, TNF-α levels, and IL-10 mRNA, TNF-α mRNA expression levels, function score, Infarct size, TUNEL + cell counts, cerebral TGF-β1 positive expression and cerebral NSE levels, and increase FADD and Daxx positive expression levels in the CIR + DSAE groups. Taken together, these results suggest that DSAE has a neuroprotective role in the CIR rats, which may be related to improvement of immunity function, proteins and genes expression.

Box–Behnken design criterion was applied to identify the significant effects of various extraction parameters such as temperature, time, and solvent–solid ratio on extraction of tea carbohydrate. Among the three variables tested extraction temperature, and solvent–solid ratio were found to have significant effect on tea carbohydrate extraction. The most suitable condition for extraction of tea carbohydrate was found to be a single step extraction at extraction temperature 90 °C, extraction time 30 min, and solvent–solid ratio 5:1. At these optimum extraction parameters, the maximum yield of tea carbohydrate obtained experimentally was found to be very close to its predicted value of 3.47% dry weight of root. Then, we have studied the influence of tea carbohydrate on biochemical parameters in hepatocellular carcinoma (HCC) animals. Hepatocellular carcinoma was induced by the injection of 1 × 10 5 H22 hepatocarcinoma cells into right hind thigh muscle in experimental animals. Tea carbohydrate could inhibit tumour growth and decrease microvessel density in tumour tissue. The altered amount of serum white blood cells (WBC), Interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) in HCC animals were dose-dependently increased, whereas activities of serum alanine transaminase (ALT), aspartate transaminase (AST) and alkaline phosphatase (ALP) were dose-dependently decreased in the drug treated animals. In addition, tea carbohydrate administration could decrease expression of vascular endothelial growth factor (VEGF) and proliferating cell nuclear antigen (PCNA) in H22 tumor tissue. It can be concluded that tea carbohydrate displayed strong antitumour activity in animals.

To evaluate the efficacy of corneal thickness and volume parameters measured with the Pentacam Scheimflug system in discriminating subclinical keratoconus corneas and normal corneas.This study included 19 patients (19 eyes) with subclinical keratoconus and 29 patients (29 eyes) with myopic astigmatism as the control group. Corneas were evaluated using a Pentacam Scheimflug system (2002 model, Oculus, Berkshire, UK). We evaluated corneal thickness and volume parameters, including central corneal thickness (CCT), minimum corneal thickness (MCT), depressed corneal thickness (DCT), maximum progression index (MaxPI), average progression index (AvPI), minimum progression index (MinPI), and corneal volume values for the 3.0 mm (CV3), 5.0 mm (CV5), and 7.0 mm (CV7) central circles. Receiver operating characteristic (ROC) curves were used to compare the sensitivity and the specificity of the parameters. Partial least squares (PLS) analysis was used to construct models with corneal thickness and volume parameters for early diagnosis.There were significant differences in all parameters (p0.001), except CV3 and CV5, between subclinical keratoconus and normal corneas. The diagnostic accuracy for all parameters was high, with an area-under-the-curve (AUC) of approximately 1. The optimal cutoff values for DCT, MinPI, AvPI, and MaxPI were 5.5, 0.95, 1.05, and 1.45 for subclinical keratoconus, respectively. The PLS model for subclinical keratoconus fit well to the CCT, MCT, MaxPI, AvPI, MinPI, CV3, and CV7 data.Thickness and volume parameters measured by the Pentacam Scheimflug system effectively discriminate subclinical keratoconus corneas from normal corneas.

The influence of Glucagon-like peptide-1 (GLP-1) and Exendin-4 on development of intrahepatic cholangiocarcinoma (ICC) is evaluated in the study. In vitro tests, including acute toxicity test, cell colony formation assays, cells proliferation and apoptosis, transwell assay, were performed. An ICC in situ tumor animal model was established. Then, animals were randomly divided into four groups (n = 6): control, Exendin-4 treatment, oxaliplatin treatment and Exendin-4-oxaliplatin treatment. Animals in the Exendin-4 treatment and Exendin-4-oxaliplatin treatment groups received a subcutaneous injection of Exendin-4 (100 μg/kg/day) for 1 week, and then received oxaliplatin (10 mg/kg/week) by tail vein injection. Animals in the control group received PBS. Immunohistochemistry tests were used for PCNA, Ki67, Caspase 3 expression in tumor tissue. Results show that that, after incubation of human cholangiocarcinoma cell lines, HuCCTI and GLP-1, or HuCCTI and Exendin-4, colony formation number was sharply decreased. However, GLP-1, HuCCTI or Exendin-4 did not affect the colony of normal cells. Combination treatment with oxaliplatin and Exendin-4 can significantly inhibit tumor cells’ proliferation and promote apoptosis. The combined effect is stronger than that of oxaliplatin or Exendin-4. Combination treatment with oxaliplatin and Exendin4 can significantly decrease Ki67 and PCNA proteins’ expression in subcutaneous tumors of nude mice. The inhibitory effect of Combination treatment with oxaliplatin and Exendin4 is clearly stronger than that of oxaliplatin. In addition, Combination treatment with oxaliplatin and Exendin4 can significantly increase Caspase3 protein positive expression. In short, these results show that combination treatment with oxaliplatin and Exendin4 can inhibit tumor cells’ proliferation, and promote apoptosis.

A 13-year-old girl presented with a 1-month history of progressive exertional dyspnea (NYHA class IV) and exophthalmos for 6 months. She had a history of long-standing asthma and the presence of allergy. Hypereosinophilia and increased serum IgE levels (2472 IU/mL) were observed. Chest radiography and a high resolution CT scan documented a massive interstitial pulmonary infiltration. Echocardiography confirmed mild tricuspid regurgitation, apical obliteration of the right ventricle by fibrocalcific thickening of the endocardium and echogenic material suggestive of thrombosis. Churg-Strauss syndrome with cardiac involvement (endomyocardiopathy) was diagnosed. The patient received anticoagulation and corticosteroid therapy. In view of rapidly progressive severe endomyocardiopathy and stable hematology, the patient was referred for cardiac surgery. Histopathological examination of resected specimens confirmed laminated thrombus but without any trace of eosinophils embedded.

To observe the effect of acupuncture and moxibustion for preventing nosocomial infection in the patient with acute cerebrovascular disease.One hundred cases of acute cerebrovascular disease were randomly divided into a control group and an observation group, 50 cases in each group. The control group were treated by routine therapeutic method without any method for preventing nosocomial infection; the observation group were treated by the routine treatment, with acupuncture and moxibustion added at Guanyuan (GV 4) and Zusanli (ST 36), once daily, for 10 days. The nosocomial infection rate and the abnormal rates of body temperature, WBC and neutrophil were investigated in the two groups.The nosocomial infection rate was 8.0% in the observation group and 26.0% in the control group with a significant difference between the two groups (P0.05), and the abnormal rates of body temperature, WBC and neutrophil in the observation group were significantly lower than those in the control group (all P0.05).Acupuncture and moxibustion can effectively prevent nosocomial infection for the patient with acute cerebrovascular disease. The mechanism possibly is related with regulative action of acupuncture and moxibustion on immunity.

To clarify the association of brain natriuretic peptide * BNP) with renal function and cardiac dysfunction in non-dialysis-dependent patients with chronic kidney disease (CKD).Fluorescence immuno-assay was used to detect the whole blood concentration of BNP in a cohort of 203 CKD patients and 16 hypertensive controls. Color ultrasonography was conducted to determine the left ventricular mass index (LVMI). Estimated glomerular filtration rate (eGFR) was examined. The relationship of BNP to eGFR and LVMI in these patients.There was a trend that the BNP level increased with the decrease of the level of eGFR [9.35 (7.35-15.00) vs 54.40 (15.10-173.00) ng/L, P0.01]. Spearman correlation showed that BNP level was correlated negatively with eGFR (r = -0.417, P0.01). Multiple regression analysis showed that eGFR was the independent determinant of BNP (beta = -0. 293, P0.01), and lgBNP concentration increased by 0.293 ng/L per 1 ml x min(-1) x (1.73 m2)(-1) reduction in lgGFR. The incidence of LV hypertrophy was much higher in the CKD patients than in the controls (53.2% vs 10.0%, P0.05). BNP level was greater in the patients with LV hypertrophy [93.05 (37.70-272.00) vs 17.30 (7.20-63.70) ng/L, P0.01], and LVMI had an independent effect on BNP concentration ( beta = 0.266, P0.01). lgBNP level increased by 0.266 ng/L per 1 g/m2 increase in lgLVMI.The declining eGFR level independently elevates the BNP level in non-dialysis-dependent CKD patients. Although renal dysfunction itself may affects the BNP concentration, LV hypertrophy is a powerful independent determinant of BNP.

The etiological types and some features of 163 in-patients with acute viral hepatitis in Xi'an in China are reported. Hepatitis A (HA) accounted for 89.2% in the age group 0-15 years, whereas hepatitis B (HB) mainly occurred at the age of 16 to 30 and non-A, non-B hepatitis 31 to 50. This is different from the age distribution in western countries. The cause of the difference is discussed. The transmission factors of NANB hepatitis might be different from those of HA and HB. Fever was more often seen in HA than in HB and NANB, while the maximal bilirubin was higher in HB than in NANB. Hepatic dysfunction of all three types of hepatitis seemed to be closely associated with the age of the patients. Of ten cases with fulminant hepatitis, none was due to hepatitis A; nine were adults.