1. The clinical and immunological features of pediatric COVID-19 patients in China
- Author
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Juan Chen, Zhen-Zhen Zhang, Yao-Kai Chen, Quan-Xin Long, Wen-Guang Tian, Hai-Jun Deng, Jie-Li Hu, Xian-Xiang Zhang, Pu-Liao, Jiang-Lin Xiang, Dao-Xin Wang, Peng Hu, Fa-Chun Zhou, Zhi-Jie Li, Hong-Mei Xu, Xue-Fei Cai, De-Qiang Wang, Yuan Hu, Ni Tang, Bei-Zhong Liu, Gui-Cheng Wu, and Ai-Long Huang
- Subjects
Clinical features ,COVID-19 ,Immune ,Paediatrics ,SARS-CoV-2 ,Medicine (General) ,R5-920 ,Genetics ,QH426-470 - Abstract
In December 2019, the corona virus disease 2019 (COVID-19) caused by novel coronavirus (SARS-CoV-2) emerged in Wuhan, China and rapidly spread worldwide. Few information on clinical features and immunological profile of COVID-19 in paediatrics. The clinical features and treatment outcomes of twelve paediatric patients confirmed as COVID-19 were analyzed. The immunological features of children patients was investigated and compared with twenty adult patients. The median age was 14.5-years (range from 0.64 to 17), and six of the patients were male. The average incubation period was 8 days. Clinically, cough (9/12, 75%) and fever (7/12, 58.3%) were the most common symptoms. Four patients (33.3%) had diarrhea during the disease. As to the immune profile, children had higher amount of total T cell, CD8+ T cell and B cell but lower CRP levels than adults (P
- Published
- 2020
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