1,014 results on '"Wenger J"'
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2. Excitation Enhancement of a Quantum Dot Coupled to a Plasmonic Antenna
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Urena, E. Bermudez, Kreuzer, M. P., Itzhakov, S., Rigneault, H., Quidant, R., Oron, D., and Wenger, J.
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Physics - Optics ,Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Plasmonic antennas are key elements to control the luminescence of quantum emitters. However, the antenna's influence is often hidden by quenching losses. Here, the luminescence of a quantum dot coupled to a gold dimer antenna is investigated. Detailed analysis of the multiply excited states quantifies the antenna's influence on the excitation intensity and the luminescence quantum yield separately.
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- 2012
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3. FCS diffusion laws on two-phases lipid membranes : experimental and Monte-carlo simulation determination of domain size
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Favard, C., Ehrig, J., Wenger, J., Lenne, P. -F., and Rigneault, H.
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Quantitative Biology - Quantitative Methods ,Condensed Matter - Soft Condensed Matter ,Physics - Biological Physics - Abstract
For more than ten years now, many efforts have been done to identify and characterize nature of obstructed diffusion in model and cellular lipid membranes. Amongst all the techniques developed for this purpose, FCS, by means of determination of FCS diffusion laws, has been shown to be a very efficient approach. In this paper, FCS diffusion laws are used to probe the behavior of a pure lipid and a lipid mixture at temperatures below and above phase transitions, both numerically, using a full thermodynamic model, and experimentally. In both cases FCS diffusion laws exhibit deviation from free diffusion and reveal the existence of domains. The variation of these domains mean size with temperature is in perfect correlation with the enthalpy fluctuation., Comment: 20 pages, 10 figures
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- 2010
4. Out-of-focus spatial map imaging of magnetically deflected sodium ammonia clusters.
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Borgeaud dit Avocat, D. P., Yang, H., Nitsche, A., Wenger, J., Yoder, B. L., and Signorell, R.
- Abstract
This paper introduces out-of-focus spatial map imaging (SMI) as a detection method for magnetic deflection of molecular/cluster beams, using Na
m (NH3 )n to illustrate its capabilities. This method enables imaging of the complete spatial distribution, simplifying measurements and allowing for cluster-size-resolved analysis by shifting away from traditional in-focus SMI conditions. Incorporating out-of-focus SMI with TOF-MS and velocity map imaging into a single setup allows for direct assessment of clusters' magnetic moments without needing to pre-select velocities. Key findings include a slower relaxation for Na(NH3 )4 compared to Na(NH3 )3 and Na(NH3 )5 , unexpectedly high deflection for larger clusters up to Na(NH3 )9 , hinting at changes in cluster dynamics as the first solvation shell closes. The study also covers the first measurements of Na2 (NH3 )1 and Na3 (NH3 )n , showing distinct deflection behaviors and underscoring the improved capabilities of the new detection method. [ABSTRACT FROM AUTHOR]- Published
- 2024
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5. List of Contributors
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Abe, Y., primary, Anspaugh, Douglas D., additional, Aoki, Takao, additional, Aponte, Raphael, additional, Arimori, Sadayuki, additional, Armel, Gregory, additional, Banba, Shinichi, additional, Barreteau, Fabien, additional, Barry, James, additional, Bartholomaeus, Anika, additional, Bartlett, Dave, additional, Berthon, Guillaume, additional, Bindschaedler, Pascal, additional, Blythe, Judith, additional, Boussemghoune, Mohamed, additional, Bowerman, Peter, additional, Bravo-Altamirano, Karla, additional, Briddell, Twyla A., additional, Buchan, Zachary, additional, Buchholz, A., additional, Campe, Ruth, additional, Cao, Xiaofeng, additional, Cassayre, Jérôme, additional, Cederbaum, Fredrik, additional, Chang, Kang, additional, Chang, Yaning, additional, Chen, Lai, additional, Chen, Xiulei, additional, Chen, Yuzhong, additional, Cheng, Jiagao, additional, Churcher, Thomas S., additional, Cordova, Daniel, additional, Cui, Dongliang, additional, Daeuble, John F., additional, Dahmen, Peter, additional, Daido, H., additional, Daniels, M., additional, DeKorver, Kyle, additional, DeLorbe, Jonathan, additional, De Mesmaeker, Alain, additional, Desbordes, Philippe, additional, Desmedt, Willem, additional, Dickhaut, Joachim, additional, Dong, Jingao, additional, El Qacemi, Myriem, additional, Essigmann, Bernd, additional, Fan, Zhijin, additional, Fehr, Marcus, additional, Flaeschel, Michael, additional, Flemming, A.J., additional, Fonné-Pfister, Raymonde, additional, Fukatsu, Kosuke, additional, Furukawa, Y., additional, Gary, Stephanie, additional, Gockel, Birgit, additional, Godfrey, C.R., additional, Godineau, E., additional, Godineau, Edouard, additional, Guan, Aiying, additional, Gutbrod, Oliver, additional, Haas, Hans Ulrich, additional, Hamada, Takahiro, additional, Hamamoto, Taku, additional, Hamer, M., additional, Hamon, Nick, additional, Harayama, Hiroto, additional, Havens, Patrick L., additional, He, Hong-Wu, additional, Heemstra, Ron, additional, Henry, Yewande T., additional, Hermann, Katrin, additional, Herrera, Rafael, additional, Herrick, Jessica, additional, Hirase, Kangetsu, additional, Hisamatsu, Akihiro, additional, Hoegger, Patrik, additional, Holyoke, Caleb W., additional, Hoppé, M., additional, Hueter, O., additional, Hughes, Kenneth A., additional, Hunter, James S., additional, Huwyler, Nikolas, additional, Inoue, Takuya, additional, Ito, Mai, additional, Iwahashi, Fukumatsu, additional, Iwasa, M., additional, Iwata, Atsushi, additional, Jia, Haowu, additional, Jones, David, additional, Kadotani, Junji, additional, Kasahara, Ryota, additional, Katsuta, H., additional, Kawahara, A., additional, Kiguchi, So, additional, Kikuchi, T., additional, Kleemann, Jochen, additional, Kloer, D.P., additional, Kobayashi, Y., additional, Komoda, M., additional, Koradin, Christopher, additional, Koyanagi, Toru, additional, Kyndt, Tina, additional, Lachia, Mathilde, additional, Lahm, George P., additional, Lal, Mukul, additional, Lamberth, Clemens, additional, Lancashire, Peter, additional, Laughlin, Laura A., additional, Leighty, Robert M., additional, Li, BaoJu, additional, Li, Honglin, additional, Li, Pengfei, additional, Li, Wei, additional, Li, Yongqiang, additional, Li, Zhong, additional, Lin, Hong-Yan, additional, Liu, Changling, additional, Loy, Brian A., additional, Lu, Aidang, additional, Lu, Yu, additional, Luksch, Torsten, additional, Lumbroso, Alexandre, additional, Ma, Hongjuan, additional, Maienfisch, Peter, additional, Mangelinckx, Sven, additional, Marrone, Pamela G., additional, Masala, Simonetta, additional, Matsumoto, M., additional, Matsuzaki, Yuichi, additional, Maue, Michael, additional, McCann, Stephen F., additional, Meng, Charles, additional, Meregalli, Giovanna, additional, Meyer, Kevin G., additional, Michrowska-Pianowska, Anna, additional, Mietzner, Thomas, additional, Mita, T., additional, Mitani, S., additional, Molt, Andrea, additional, Morell, Mauricio, additional, Morita, Masayuki, additional, Muehlebach, M., additional, Murata, Tetsuya, additional, Nakamoto, Kenichi, additional, Nakamura, Y., additional, Nakao, T., additional, Nan, Jia-Xu, additional, Newton, Trevor, additional, Nokura, Yoshihiko, additional, Nomura, M., additional, Nourani, R., additional, Oliver, S., additional, Ōmura, Satoshi, additional, Oyama, Kazuhiko, additional, Pahutski, Thomas F., additional, Papineni, Sabitha, additional, Patre, Rupesh, additional, Paulini, Ralph, additional, Peng, Hao, additional, Perruccio, F., additional, Pitterna, Thomas, additional, Pohlman, Matthias, additional, Popp, C., additional, Porri, Aimone, additional, Prasanna, C.S., additional, Qian, Xuhong, additional, Qu, Ren-Yu, additional, Rajan, Ramya, additional, Rankl, Nancy B., additional, Rawal, Girish, additional, Rendine, Stefano, additional, Renold, Peter, additional, Rigoli, Jared, additional, Röckl, Johannes, additional, Sakaguchi, Hiroshi, additional, Salgado, Vincent L., additional, Satoh, Eikoh, additional, Schaetzer, J., additional, Schröder, Hartwig, additional, Schwarz, Hans-Georg, additional, Screpanti, Claudio, additional, Seitz, Thomas, additional, Senn, R., additional, Shan, Guomin, additional, Shao, Xusheng, additional, Shen, Hongfeng, additional, Sherrard-Smith, Ellie, additional, Shi, Qinjie, additional, Shi, Yanxia, additional, Shigematsu, Yoshio, additional, Shino, Mamiko, additional, Sierotzki, Helge, additional, Simon, Anja, additional, Slater, R., additional, Smejkal, Tomas, additional, Smits, Helmars, additional, Soergel, Sebastian, additional, Song, Hongjian, additional, Stafford, D., additional, Stierli, Daniel, additional, Strickman, Daniel, additional, Sulzer-Mosse, Sarah, additional, Suwa, Akiyuki, additional, Takahashi, Masaki, additional, Tan, Xiao-song, additional, Tinwell, Helen, additional, Tong, My-Hanh T., additional, Tsukamoto, Masamitsu, additional, Tsukamoto, Yoshihisa, additional, Tsukuda, S., additional, Vanholme, Bartel, additional, Viner, Russell, additional, Vock-Hatt, F., additional, Vogt, Juliane, additional, Wakita, T., additional, Walter, Harald, additional, Wang, Gaolei, additional, Wang, Nick X., additional, Wang, Qingmin, additional, Wang, Tao, additional, Wang, Ziwen, additional, Wege, P., additional, Weimer, Monte R., additional, Wenger, J., additional, Wildsmith, L., additional, Willis, Derek W., additional, Wilmot, Jeremy, additional, Winter, Christian, additional, Witschel, Matthias, additional, Wu, Qiao, additional, Xiao, Youxin, additional, Xu, Ming, additional, Xu, Xiaoyong, additional, Xu, Yufang, additional, Xu, Zheng, additional, Yamada, Hiroji, additional, Yan, Yao-Chao, additional, Yang, Guang-Fu, additional, Yang, Jichun, additional, Yang, Wen-Chao, additional, Yao, Chenglin, additional, Yoneda, T., additional, Yoshimoto, Yuya, additional, Young, David, additional, Yuan, Jun-Lin, additional, Zambach, W., additional, Zhang, Jingjing, additional, Zhang, Jingwei, additional, Zhang, Ruifeng, additional, Zhang, Wenming, additional, Zhao, Bin, additional, Zhao, Zhenjiang, additional, Zhou, Cong, additional, Zhou, Yuan, additional, and Zhu, Weiping, additional
- Published
- 2021
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6. Spiropidion discovery: Broad spectrum control of sucking insects and mites for multicrop utility
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Muehlebach, M., primary, Schaetzer, J., additional, Buchholz, A., additional, Flemming, A.J., additional, Godfrey, C.R., additional, Godineau, E., additional, Hamer, M., additional, Vock-Hatt, F., additional, Hueter, O., additional, Kloer, D.P., additional, Maienfisch, Peter, additional, Oliver, S., additional, Perruccio, F., additional, Pitterna, Thomas, additional, Popp, C., additional, Senn, R., additional, Slater, R., additional, Smejkal, Tomas, additional, Stafford, D., additional, Wenger, J., additional, Wildsmith, L., additional, and Zambach, W., additional
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- 2021
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7. Pulsed squeezed vacuum characterization without homodyning
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Wenger, J., Fiurasek, J., Tualle-Brouri, R., Cerf, N. J., and Grangier, Ph.
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Quantum Physics - Abstract
Direct photon detection is experimentally implemented to measure the squeezing and purity of a single-mode squeezed vacuum state without an interferometric homodyne detection. Following a recent theoretical proposal [arXiv quant-ph/0311119], the setup only requires a tunable beamsplitter and a single-photon detector to fully characterize the generated Gaussian states. The experimental implementation of this procedure is discussed and compared with other reference methods., Comment: 8 pages, 7 figures
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- 2004
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8. Proposal for a loophole-free Bell test using homodyne detection
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Sanchez, R. Garcia-Patron, Fiurasek, J., Cerf, N. J., Wenger, J., Tualle-Brouri, R., and Grangier, Ph.
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Quantum Physics - Abstract
We propose a feasible optical setup allowing for a loophole-free Bell test with efficient homodyne detection. A non-gaussian entangled state is generated from a two-mode squeezed vacuum by subtracting a single photon from each mode, using beamsplitters and standard low-efficiency single-photon detectors. A Bell violation exceeding 1% is achievable with 6-dB squeezed light and an homodyne efficiency around 95%. A detailed feasibility analysis, based upon the recent generation of single-mode non-gaussian states, confirms that this method opens a promising avenue towards a complete experimental Bell test., Comment: 4 pages RevTex, 2 figures
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- 2004
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9. Non-gaussian statistics from individual pulses of squeezed light
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Wenger, J., Tualle-Brouri, R., and Grangier, P.
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Quantum Physics - Abstract
We describe the observation of a degaussification protocol that maps individual pulses of squeezed light onto non-Gaussian states. This effect is obtained by sending a small fraction of the squeezed vacuum beam onto an avalanche photodiode, and by conditioning the single-shot homodyne detection of the remaining state upon the photon-counting events. The experimental data provides a clear evidence of phase-dependent non-Gaussian statistics. This protocol is closely related to the first step of an entanglement distillation procedure for continuous variables., Comment: Accepted for publication in Phys. Rev. Lett
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- 2004
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10. Pulsed homodyne measurements of femtosecond squeezed pulses generated by single-pass parametric deamplification
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Wenger, J., Tualle-Brouri, R., and Grangier, P.
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Quantum Physics - Abstract
A new scheme is described for pulsed squeezed light generation using femtosecond pulses parametrically deamplified through a single pass in a thin (0.1mm) potassium niobate KNbO3 crystal, with a significant deamplification of about -3dB. The quantum noise of each individual pulse is registered in the time domain using a single-shot homodyne detection operated with femtosecond pulses and the best squeezed quadrature variance was measured to be 1.87 dB below the shot noise level. Such a scheme provides the basic ressource for time-resolved quantum communication protocols., Comment: Accepted for publication in Optics Letters
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- 2004
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11. Quantum key distribution using gaussian-modulated coherent states
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Grosshans, F., Van Assche, G., Wenger, J., Brouri, R., Cerf, N. J., and Grangier, Ph.
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Quantum Physics - Abstract
Quantum continuous variables are being explored as an alternative means to implement quantum key distribution, which is usually based on single photon counting. The former approach is potentially advantageous because it should enable higher key distribution rates. Here we propose and experimentally demonstrate a quantum key distribution protocol based on the transmission of gaussian-modulated coherent states (consisting of laser pulses containing a few hundred photons) and shot-noise-limited homodyne detection; squeezed or entangled beams are not required. Complete secret key extraction is achieved using a reverse reconciliation technique followed by privacy amplification. The reverse reconciliation technique is in principle secure for any value of the line transmission, against gaussian individual attacks based on entanglement and quantum memories. Our table-top experiment yields a net key transmission rate of about 1.7 megabits per second for a loss-free line, and 75 kilobits per second for a line with losses of 3.1 dB. We anticipate that the scheme should remain effective for lines with higher losses, particularly because the present limitations are essentially technical, so that significant margin for improvement is available on both the hardware and software., Comment: 8 pages, 4 figures
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- 2003
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12. Virtual Entanglement and Reconciliation Protocols for Quantum Cryptography with Continuous Variables
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Grosshans, F., Cerf, N. J., Wenger, J., Tualle-Brouri, R., and Grangier, Ph.
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Quantum Physics - Abstract
We discuss quantum key distribution protocols using quantum continuous variables. We show that such protocols can be made secure against individual gaussian attacks regardless the transmission of the optical line between Alice and Bob. This is achieved by reversing the reconciliation procedure subsequent to the quantum transmission, that is, using Bob's instead of Alice's data to build the key. Although squeezing or entanglement may be helpful to improve the resistance to noise, they are not required for the protocols to remain secure with high losses. Therefore, these protocols can be implemented very simply by transmitting coherent states and performing homodyne detection. Here, we show that entanglement nevertheless plays a crucial role in the security analysis of coherent state protocols. Every cryptographic protocol based on displaced gaussian states turns out to be equivalent to an entanglement-based protocol, even though no entanglement is actually present. This equivalence even holds in the absence of squeezing, for coherent state protocols. This ``virtual'' entanglement is important to assess the security of these protocols as it provides an upper bound on the mutual information between Alice and Bob if they had used entanglement. The resulting security criteria are compared to the separability criterion for bipartite gaussian variables. It appears that the security thresholds are well within the entanglement region. This supports the idea that coherent state quantum cryptography may be unconditionally secure., Comment: 18 pages, 6 figures. Submitted to QIC
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- 2003
13. Capsule Switching of Neisseria meningitidis
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Swartley, J. S., Marfin, A. A., Edupuganti, S., Cieslak, P., Perkins, B., Wenger, J. D., and Stephens, D. S.
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- 1997
14. Surface chemistry of the group IIB metal dimethyls on platinum
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Wenger, J. C.
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541 ,Physical chemistry - Published
- 1993
15. Survey of American Catholic Priests, 2001
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Hoge, D. and Wenger, J.
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- 2022
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16. Réparation cœlioscopique des prolapsus des organes pelviens par suspension prothétique latérale : une série continue de 218 patientes
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Dubuisson, J.-B., Eperon, I., Jacob, S., Dubuisson, J., Wenger, J.-M., Dallenbach, P., and Kaelin-Gambirasio, I.
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- 2011
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17. CMOS-compatible all-dielectric metalens for improving pixel photodetector arrays
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Mikheeva, E, Claude, J, Salomoni, M, Wenger, J, Lumeau, J, Abdeddaim, R, Ficorella, A, Gola, A, Paternoster, G, Paganoni, M, Auffray, E, Lecoq, P, Enoch, S, Mikheeva E., Claude J. -B., Salomoni M., Wenger J., Lumeau J., Abdeddaim R., Ficorella A., Gola A., Paternoster G., Paganoni M., Auffray E., Lecoq P., Enoch S., Mikheeva, E, Claude, J, Salomoni, M, Wenger, J, Lumeau, J, Abdeddaim, R, Ficorella, A, Gola, A, Paternoster, G, Paganoni, M, Auffray, E, Lecoq, P, Enoch, S, Mikheeva E., Claude J. -B., Salomoni M., Wenger J., Lumeau J., Abdeddaim R., Ficorella A., Gola A., Paternoster G., Paganoni M., Auffray E., Lecoq P., and Enoch S.
- Abstract
Metasurfaces and, in particular, metalenses have attracted large interest and enabled various applications in the near-infrared and THz regions of the spectrum. However, the metalens design in the visible range stays quite challenging due to the smaller nanostructuring scale and the limited choice of lossless CMOS-compatible materials. We develop a simple yet efficient design of a polarization-independent, broadband metalens suitable for many CMOS-compatible fabrication techniques and materials and implement it for the visible spectral range using niobium pentoxide (Nb2O5). The produced metalens demonstrates high transmittance and focusing ability as well as a large depth of focus, which makes it a promising solution for a new generation of silicon photomultiplier photodetectors with reduced fill factor impact on the performance and reduced electron-hole generation regions, which altogether potentially leads to improved photodetection efficiency and other characteristics.
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- 2020
18. Complete Writings Menno Simons
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J. C. Wenger, J C Wenger
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- 2010
19. Arteriography in Avascular Necrosis of the Femoral Head
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Kehr, P., Steib, J.-P., Wenger, J.-J., Mitteau, M., Lang, G., Arlet, J., editor, and Mazières, B., editor
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- 1990
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20. Ribosomal DNA Fingerprinting of Listeria monocytogenes Using a Digoxigenin-Labeled DNA Probe
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Graves, L. M., Swaminathan, B., Reeves, M. W., and Wenger, J.
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- 1991
21. Chapter 13 - Spiropidion discovery: Broad spectrum control of sucking insects and mites for multicrop utility
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Muehlebach, M., Schaetzer, J., Buchholz, A., Flemming, A.J., Godfrey, C.R., Godineau, E., Hamer, M., Vock-Hatt, F., Hueter, O., Kloer, D.P., Maienfisch, Peter, Oliver, S., Perruccio, F., Pitterna, Thomas, Popp, C., Senn, R., Slater, R., Smejkal, Tomas, Stafford, D., Wenger, J., Wildsmith, L., and Zambach, W.
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- 2021
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22. Supplement to: Vitamin D-binding protein and vitamin C status of black Americans and white Americans
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Powe, C E, Evans, M N, and Wenger, J
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- 2013
23. Immunogenicity of Two Efficacious Outer Membrane Protein-Based Serogroup B Meningococcal Vaccines among Young Adults in Iceland
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Perkins, B. A., Jonsdottir, K., Briem, H., Griffiths, E., Plikaytis, B. D., Hoiby, E. A., Rosenqvist, E., Holst, J., Nokleby, H., Sotolongo, F., Sierra, G., Campa, H. C., Carlone, G. M., Williams, D., Dykes, J., Kapczynski, D., Tikhomirov, E., Wenger, J. D., and Broome, C. V.
- Published
- 1998
24. Molecular Epidemiology of Sporadic (Endemic) Serogroup C Meningococcal Disease
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Raymond, N. J., Reeves, M., Ajello, G., Baughman, W., Gheesling, L. L., Carlone, G. M., Wenger, J. D., and Stephens, D. S.
- Published
- 1997
25. Providing monovalent oral polio vaccine type I to newborns: findings from a pilot birth-dose project in Moradabad district, India/ Delivrance du vaccin antipoliomyelitique oral monovalent type 1 aux nouveau-nes : resultats d'un projet pilote prevoyant l'administration a la naissance d'une premiere dose de ce vaccin dans le district de Moradabad,
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Rainey, J.J., Bhatnagar, P., Estivariz, C.F., Durrani, S., Galway, M., Sandhu, H., Bahl, S., Jafari, H., and Wenger, J.
- Subjects
United Nations. Children's Fund -- Media coverage ,Media coverage ,Vaccines -- Media coverage ,Newborn infants ,Public health ,Medical research ,Vaccination ,Poliomyelitis ,Medicine, Experimental ,Infants (Newborn) - Abstract
Providing monovalent oral polio vaccine type I to newborns: findings from a pilot birth-dose project in Moradabad district, India/ Delivrance du vaccin antipoliomyelitique oral monovalent type 1 aux nouveau-nes : [...], Problem Poliovirus transmission remained a public health challenge in western Uttar Pradesh, India in late 2005 and early 2006. In 2006, the India Expert Advisory Group for Polio Eradication concluded that, given the peak incidence of polio among children 6 to 12 months of age, a targeted birth dose of oral polio vaccine may be necessary to interrupt intense poliovirus transmission in high risk areas. Approach The Govemment of Uttar Pradesh, the National Polio Surveillance Project and the United Nations Children's Fund (UNICEF) implemented a pilot birth-dose project aimed at identifying and vaccinating all newborns with a dose of oral polio vaccine within 72 hours of birth in an effort to evaluate operational feasibility and potential impact on population immunity. Local setting The project was piloted in Moradabad district: zone 7 in Moradabad City (urban setting), Kunderki block (rural setting) and in select birthing hospitals. Relevant changes Between July 2006 and February 2007, 9740 newborns were identified, of which 6369 (65%) were vaccinated by project personnel within 72 hours of birth. Project coverage (for total newborns vaccinated) ranged from 39% (in zone 7) to 76% (in Kunderki block) of the estimated number of newborns vaccinated during previous supplemental immunization activities. Lessons learned Birth-dose coverage among newborns was lower than expected. Expansion costs were estimated to be high, with marginal impact. The project, however, provided opportunities to strengthen newborn tracking systems which have increased the number of newborns and young infants vaccinated during supplemental immunization activities and enrolled in routine programmes. Problematique La transmission du poliovirus restait un grand probleme de sante publique dans l'Ouest de l'Uttar Pradesh a la fin de l'annee 2005 et debut 2006. En 2006, le Groupe consultatif d'experts indien pour l'eradication de la polio avait conclu que, compte tenu du pic atteint par l'incidence de cette maladie chez les enfants entre 6 et 12 mois, l'administration ciblee a la naissance d'une dose de vaccin antipoliomyelitique oral pouvait etre necessaire pour interrompre la transmission intense du poliovirus dans les zones a haut risque. Demarche Le Gouvernement de l'Uttar Pradesh, le Projet national de surveillance de la polio et le Fonds des Nations Unies pour l'enfance (UNICEF) ont mis en oeuvre un projet pilote d'administration du vaccin a la naissance, visant a identifier et a vacciner tous les nouveau-nes avec une dose de vaccin antipoliomyelitique oral dans les 72 heures suivant la naissance, dans le cadre d'un effort pour evaluer la faisabilite operationnelle de cette intervention et son impact eventuel sur l'immunite de la population. Contexte local Le projet a ete mene dans le district de Moradabad : zone 7 de la ville de Moradabad (contexte urbain), agglomeration de Kunderki (contexte rural) et dans certaines maternites. Modifications pertinentes Entre juillet 2006 et fevrier 2007, 9740 nouveau-nes ont ete identifies, parmi lesquels 6369 (65 %) ont ete vaccines par des personnes travaillant pour le projet dans les 72 h suivant la naissance. La couverture par le projet (pour l'ensemble des nouveau-nes vaccines) se situait entre 39 % (zone 7) et 76 % (quartier de Kunderki) du nombre estime de nouveaunes vaccines pendant les activites de vaccination supplementaires menees anterieurement. Enseignements tires La couverture par une dose a la naissance des nouveau-nes etait plus faible qu'attendu. Les couts d'elargissement de cette couverture ont ete evalues comme eleves, avec un impact correspondant marginal. Le projet a neanmoins fourni la possibilite de renforcer les systemes permettant de retrouver les nouveau-nes, d'ou une progression de nombre de nouveau-nes et de jeunes nourrissons vaccines dans le cadre des activites de vaccination supplementaires et soumis aux programmes de vaccination systematique. Problema A finales de 2005 y principios de 2006 la transmision del poliovirus seguia planteando un problema de salud publica en Uttar Pradesh occidental, India. En 2006, el Grupo Consultivo de Expertos para la Erradicacion de la Poliomielitis de la India llego a la conclusion de que, a la vista de la incidencia maxima de poliomielitis entre Ios ninos de 6 a 12 meses, probablemente se requeria una dosis neonatal focalizada de vacuna antipoliomielitica oral para interrumpir la intensa transmision del poliovirus observada en las zonas de alto riesgo. Enfoque El Gobierno de Uttar Pradesh, el Proyecto Nacional de Vigilancia de la Poliomielitis y el Fondo de las Naciones Unidas para la Infancia (UNICEF) pusieron en marcha un proyecto piloto de administracion de una dosis al nacer basado en localizar y vacunar a todos los recien nacidos con una dosis de vacuna antipoliomielitica oral en las primeras 72 horas de vida, con la finalidad de evaluar la viabilidad operacional y el impacto potencial de esa medida en la inmunidad de la poblacion. Contexto local El proyecto piloto tuvo como escenario el distrito de Moradabad: la zona 7 de la ciudad de Moradabad (entorno urbano), la aglomeracion de Kunderki (entorno rural) y varios hospitales de maternidad. Cambios destacables Entre julio de 2006 y febrero de 2007 se registraron 9740 recien nacidos, 6369 de los cuales (65%) fueron vacunados por personal del proyecto en las 72 horas siguientes al nacimiento. La cobertura del proyecto (numero total de recien nacidos vacunados) se situo entre el 39% (zona 7) y el 76% (Kunderki) del numero estimado de neonatos vacunados en las actividades suplementarias de inmunizacion anteriores. Ensenanzas extraidas La cobertura de administracion de una dosis a los neonatos al poco de nacer fue inferior a la prevista. Se estima que el costo de la expansion fue elevado y su impacto, insignificante. El proyecto, sin embargo, brindo oportunidades para reforzar unos sistemas de seguimiento de los recien nacidos que han permitido aumentar el numero de neonatos y lactantes de corta edad vacunados en las actividades suplementarias de inmunizacion e incluidos en los programas de vacunacion sistematica. [TEXT NOT REPRODUCIBLE IN ASCII.]
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- 2009
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26. Simulation Chamber Studies of the Atmospheric Oxidation of 2-Methyl-3-Buten-2-ol: Reaction with Hydroxyl Radicals and Ozone Under a Variety of Conditions
- Author
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Carrasco, N., Doussin, J. F., O’Connor, M., Wenger, J. C., Picquet-Varrault, B., Durand-Jolibois, R., and Carlier, P.
- Published
- 2007
- Full Text
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27. Time-resolved homodyne characterization of individual quadrature-entangled pulses
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Wenger, J., Ourjoumtsev, A., Tualle-Brouri, R., and Grangier, P.
- Published
- 2005
- Full Text
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28. Cost and resource implications with serum angiogenic factor estimation in the triage of pre-eclampsia
- Author
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Schnettler, W T, Dukhovny, D, Wenger, J, Salahuddin, S, Ralston, S J, and Rana, S
- Published
- 2013
- Full Text
- View/download PDF
29. Kinetic Studies of OH and O3 Reactions with Allyl and Isopropenyl Acetate
- Author
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Le Calvé, S., Mellouki, A., Le Bras, G., Treacy, J., Wenger, J., and Sidebottom, H.
- Published
- 2000
- Full Text
- View/download PDF
30. Fabrication of spectrally sharp Si-based dielectric resonators: combining etaloning with Mie resonances
- Author
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Toliopoulos, D., primary, Khoury, M., additional, Bouabdellaoui, M., additional, Granchi, N., additional, Claude, J.-B., additional, Benali, A., additional, Berbezier, I., additional, Hannani, D., additional, Ronda, A., additional, Wenger, J., additional, Bollani, M., additional, Gurioli, M., additional, Sanguinetti, S., additional, Intonti, F., additional, and Abbarchi, M., additional
- Published
- 2020
- Full Text
- View/download PDF
31. CMOS-compatible all-dielectric metalens for improving pixel photodetector arrays
- Author
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Mikheeva, E., primary, Claude, J.-B., additional, Salomoni, M., additional, Wenger, J., additional, Lumeau, J., additional, Abdeddaim, R., additional, Ficorella, A., additional, Gola, A., additional, Paternoster, G., additional, Paganoni, M., additional, Auffray, E., additional, Lecoq, P., additional, and Enoch, S., additional
- Published
- 2020
- Full Text
- View/download PDF
32. Comparison of Heated Electrospray Ionization and Nanoelectrospray Ionization Sources Coupled to Ultra-High-Resolution Mass Spectrometry for Analysis of Highly Complex Atmospheric Aerosol Samples
- Author
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Kourtchev, I., primary, Szeto, P., additional, O’Connor, I., additional, Popoola, O. A. M., additional, Maenhaut, W., additional, Wenger, J., additional, and Kalberer, M., additional
- Published
- 2020
- Full Text
- View/download PDF
33. Kinetic and mechanistic study of OH- and Cl-initiated oxidation of two unsaturated HFCs: C4F9CH=CH2 and C6F13CH=CH2
- Author
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Vesine, E., Bossoutrot, V., Mellouki, A., Bras, G. Le, Wenger, J., and Sidebottom, H.
- Subjects
Decomposition (Chemistry) -- Analysis ,Chlorine -- Chemical properties ,Oxidation-reduction reaction -- Analysis ,Chemicals, plastics and rubber industries - Abstract
The kinetics and mechanisms of the OH- and Cl-initiated oxidation of two unsaturated HFCs, C4F9CH=CH2 and C6F13CH=CH2 were studied. The results of the experiment are consistent with the significantly higher activation barrier for the decomposition of the B-chloroxy, compared to that of the B-hydroxyoxy radicals.
- Published
- 2000
34. Abstracts of the 6th FECS Conference 1998 Lectures
- Author
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Rowland, F. Sherwood, Blake, Donald R., Larsen, B. R., Lindskog, Anne, Peterson, Peter J., Williams, W. Peter, Wallington, T. J., Pilling, M. J., Carslaw, N., Creasey, D. J., Heard, D. E., Jacobs, P., Lee, J., Lewis, A. C., McQuaid, J. B., Stockwell, William R., Frank, Hartmut, Sacco, P., Cocheo, V., Lynge, E., Andersen, A., Nilsson, R., Barlow, L., Pukkala, E., Nordlinder, R., Boffetta, P., Grandjean, P., Heikkil, P., Hürte, L. G., Jakobsson, R., Lundberg, I., Moen, B., Partanen, T., Riise, T., Borowiak, A., De Saeger, E., Schnitzler, K. G., Gravenhorst, G., Jacobi, H. W., Moelders, S., Lammel, G., Busch, G., Beese, F. O., Dentener, F. J., Feichter, J., Fraedrich, K., Roelofs, G. J., Friedrich, R., Reis, S., Voehringer, F., Simpson, D., Moussiopoulos, N., Sahm, P., Tourlou, P. M., Salmons, R., Papameletiou, D., Maqueda, J. M., Suhr, Per B., Bell, W., Paton-Walsh, C., Woods, P. T., Partridge, R. H., Slemr, J., Slemr, F., Schmidbauer, N., Ravishankara, A. R., Jenkin, Michael E., de Leeuw, G., van Eijk, A. M. J., Flossmann, A. I., Wobrock, W., Mestayer, P. G., Tranchant, B., Ljungström, E., Karlsson, R., Larsen, S. E., Roemer, M., Builtjes, P. J. H., Koffi, Brigitte, Koffi, Ernest N’Dri, De Saeger, Emile, Ro-Poulsen, H., Mikkelsen, T. N., Hummelshøj, P., Hovmand, M. F., Simoneit, Bernd R. T., van der Meulen, A., Meyer, Michael B., Berndt, T., Böge, O., Stratmann, F., Cass, Glen R., Harrison, Roy M., Shi, Ji Ping, Hoffmann, T., Warscheid, B., Bandur, R., Marggraf, U., Nigge, W., Kamens, Richard, Jang, Myoseon, Strommen, Mike, Chien, Chao-Jung, Leach, Keri, Ammann, M., Kalberer, M., Arens, F., Lavanchy, V., Gâggeler, H. W., Baltensperger, U., Davies, J. A., Cox, R. A., Alonso, S. García, Pastor, R. Pérez, Argüello, Gustavo A., Willner, Helge, Berndt, T., Böge, O., Bogillo, V. I., Pokrovskiy, V. A., Kuraev, O. V., Gozhyk, P. F., Bolzacchini, E., Bruschi, M., Fantucci, P., Meinardi, S., Orlandi, M., Rindone, B., Bolzacchini, Ezio, Bohn, Birger, Rindone, Bruno, Bruschi, Maurizo, Zetzsch, Cornelius, Brussol, C., Duane, M., Larsen, B., Carlier, P., Kotzias, D., Caracena, A. Baeza, Aznar, A. Miñana, Ferradás, E. González, Christensen, C. S., Skov, H., Hummelshøj, P., Jensen, N. O., Lohse, C., Cocheo, V., Sacco, P., Chatzis, C., Cocheo, V., Sacco, P., Boaretto, C., Quaglio, F., Zaratin, L., Pagani, D., Cocheo, L., Cocheo, Vincenzo, Asnar, Agustin Minana, Baldan, Annerita, Ballesta, Pascual P., Boaretto, Caterina, Caracena, Antonia B., Ferradas, Enrique Gonzalez, Gonzalez-Flesca, Nobert, Goelen, Eddie, Hansen, Asger B., Sacco, Paolo, De Saeger, Emile, Skov, Henrik, Consonni, V., Gramatica, P., Santagostino, A., Galvani, P., Bolzacchini, E., Consonni, Viviana, Gramatica, Paola, Todeschini, Roberto, Dippel, G., Reinhardt, H., Zellner, R., Dämmer, K., Bednarek, G., Breil, M., Zellner, R., Febo, A., Allegrini, I., Giliberti, C., Perrino, C., Fogg, P. G. T., Geiger, H., Barnes, I., Becker, K. H., Maurer, T., Geyskens, F., Bormans, R., Lambrechts, M., Goelen, E., Giese, Martina, Frank, Hartmut, Glasius, M., Hornung, P., Jacobsen, J. K., Klausen, H. S., Klitgaard, K. C., Møller, C. K., Petersen, A. P. F., Petersen, L. S., Wessel, S., Hansen, T. S., Lohse, C., Boaretto, E., Heinemeier, J., Glasius, M., Di Bella, D., Lahaniati, M., Calogirou, A., Jensen, N. R., Hjorth, J., Kotzias, D., Larsen, B. R., Gonzalez-Flesca, N., Cicolella, A., Bates, M., Bastin, E., Gurbanov, M. A., Akhmedly, K. M., Balayev, V. S., Haselmann, K. F., Ketola, R., Laturnus, F., Lauritsen, F. R., Grøn, C., Herrmann, H., Ervens, B., Reese, A., Umschlag, Th., Wicktor, F., Zellner, R., Herrmann, H., Umschlag, Th., Müller, K., Bolzacchini, E., Meinardi, S., Rindone, B., Jenkin, Michael E., Hayman, Garry D., Jensen, N. O., Courtney, M., Hummelshøj, P., Christensen, C. S., Larsen, B. R., Johnson, Matthew S., Hegelund, Flemming, Nelander, Bengt, Kirchner, Frank, Klotz, B., Barnes, Ian, Sørensen, S., Becker, K. H., Etzkorn, T., Platt, U., Wirtz, K., Martín-Reviejo, M., Laturnus, Frank, Martinez, E., Cabañas, B., Aranda, A., Martín, P., Salgado, S., Rodriguez, D., Masclet, P., Jaffrezo, J. L., Hillamo, R., Mellouki, A., Le Calvé, S., Le Bras, G., Moriarty, J., O’Donnell, S., Wenger, J., Sidebottom, H., Mingarrol, M. T. Bomboi, Cosin, S., Pastor, R. Pérez, Alonso, S. García, Sanz, M. J., Bravo, I., Gonzalez, D., Pérez, M. A., Mustafaev, Islam, Mammadova, Saida, Noda, J., Hallquist, M., Langer, S., Ljungström, E., Nohara, K., Kutsuna, S., Ibusuki, T., Oehme, Michael, Kölliker, Stephan, Brombacher, Stephan, Merz, Leo, Pastor, R. Pérez, Alonso, S. García, Cabezas, A. Quejido, Peeters, J., Vereecken, L., El Yazal, J., Pfeffer, Hans-Ulrich, Breuer, Ludger, Platz, J., Nielsen, O. J., Sehested, J., Wallington, T. J., Ball, J. C., Hurley, M. D., Straccia, A. M., Schneider, W. F., Pérez-Casany, M. P., Nebot-Gil, I., Sánchez-Marín, J., Putz, E., Folberth, G., Pfister, G., Weissflog, L., Elansky, N. P., Sørensen, Søren, Barnes, Ian, Becker, K. H., Shao, M., Heiden, A. C., Kley, D., Rockel, P., Wildt, J., Silva, G. V. A., Vasconcelos, M. T., Fernandes, E. O., Santos, A. M. S., Skov, Henrik, Hansen, Asger, Løfstrøm, Per, Lorenzen, Gitte, Stabel, J. R., Wolkoff, P., Pedersen, T., Strom, A. B., Skov, Henrik, Hertel, Ole, Jensen, Finn Palmgren, Hjorth, Jens, Galle, Bosse, Wallin, Svante, Theloke, J., Libuda, H. G., Zabel, F., Touaty, Muriel, Bonsang, Bernard, Ullerstam, M., Langer, S., Ljungström, E., Wenger, John, Bonard, Amélie, Manning, Marcus, Nolan, Sinéad, O’Sullivan, Niamh, Sidebottom, Howard, Wenger, John, Collins, Eoin, Moriarty, Jennie, O’Donnell, Sinéad, Sidebottom, Howard, Wenger, John, Collins, Eoin, Moriarty, Jennie, O’Donnell, Sinéad, Sidebottom, Howard, Wenger, John, Sidebottom, Howard, Chadwick, Paul, O’Leary, Barbara, Treacy, Jack, Wolkoff, Peder, Clausen, Per A., Wilkins, Cornelius K., Hougaard, Karin S., Nielsen, Gunnar D., Zilinskis, Viktors, Jansons, Guntis, Peksens, Aigars, Lazdins, Agris, Arinci, Y. V., Erdöl, N., Ekinci, E., Okutan, H., Manlafalioglu, I., Bakeas, Evangelos B., Siskos, Panayotis A., Viras, Loizos G., Smirnioudi, Vasiliki N., Bottenheim, Jan W., Biesenthal, Thomas, Gong, Wanmin, Makar, Paul, Delmas, Véronique, Menard, Tamara, Tatry, Véronique, Moussafir, Jacques, Thomas, Dominique, Coppalle, Alexis, Ellermann, Thomas, Hertel, Ole, Skov, Henrik, Frohn, Lise, Manscher, Ole H., Friis, Jørgen, Girgzdiene, Rasa, Girgzdys, Aloyzas, Gurevich, N. A., Gårdfeldt, Katarina, Langer, Sarka, Hermans, C., Vandaele, A. C., Carleer, M., Fally, S., Colin, R., Bernath, P. F., Jenouvrier, A., Coquart, B., Mérienne, M. -F., Hertel, Ole, Frohn, Lise, Skov, Henrik, Ellermann, Thomas, Huntrieser, H., Schlager, H., Feigl, C., Kemp, Kåre, Palmgren, Finn, Kiilsholm, Sissi, Rasmussen, Alix, Sørensen, Jens Havskov, Klemm, Otto, Lange, Holger, Larsen, René Wugt, Larsen, Niels Wessel, Nicolaisen, Flemming, Sørensen, Georg Ole, Beukes, Jon Are, Larsen, Poul Bo, Jensen, Steen Solvang, Fenger, Jes, de Leeuw, Gerrit, Kunz, Gerard, Cohen, Leo, Schlünzen, Heinke, Muller, Frank, Schulz, Michael, Tamm, Susanne, Geernaert, Gary, Hertel, Ole, Pedersen, Britta, Geernaert, Lise Lotte Sørensen, Lund, Søren, Vignati, Elisabetta, Jickells, Tim, Spokes, Lucinda, Matei, C., Jinga, O. A., Jinga, D. C., Moliner, R., Braekman-Danheux, C., Fontana, A., Suelves, I., Thieman, T., Vassilev, S., Skov, Henrik, Hertel, Ole, Zlatev, Zahari, Brandt, Jørgen, Bastrup-Birk, Annemarie, Ellermann, Thomas, Frohn, Lise, Vandaele, A. C., Hermans, C., Carleer, M., Tsouli, A., Colin, R., Windsperger, Andreas M., Turi, Kristina, Dworak, Oliver, Zellweger, C., Weingartner, E., Rüttimann, R., Hofer, P., Baltensperger, U., Ziv, A., Iakovleva, E., Palmgren, F., Berkovicz, R., Skov, H., Alastuey, A., Querol, X., Chaves, A., Lopez-Soler, A., Ruiz, C., Andrees, J. M., Allegrini, I., Febo, A., Giusto, M., Angeloni, M., Di Filippo, P., D’Innocenzio, F., Lepore, L., Marconi, A., Arshinov, M. Yu., Belan, B. D., Davydov, D. K., Kovaleskii, V. K., Plotinov, A. P., Pokrovskii, E. V., Sklyadneva, T. K., Tolmachev, G. N., Arshinov, M. Yu., Belan, B. D., Sklyadneva, T. K., Behnke, Wolfgang, Elend, Manfred, Krüger, Ulrich, Zetzsch, Cornelius, Belan, B. D., Arshinov, M. Yu., Davydov, D. K., Kovalevskii, V. K., Plotnikov, A. P., Pokrovskii, E. V., Rasskazchikova, T. M., Sklyadneva, T. K., Tolmachev, G. N., Belan, B. D., Arshinov, M. Yu., Simonenkov, D. V., Tolmachev, G. N., Bilde, Merete, Aker, Pamela M., Börensen, C., Kirchner, U., Scheer, V., Vogt, R., Ellermann, T., Geernaert, L. L. S., Pryor, S. C., Barthelmie, R. J., Feilberg, Anders, Nielsen, Torben, Kamens, Richard M., Freitas, M. C., Marques, A. P., Reis, M. A., Alves, L. C., Ilyinskikh, N. N., Ilyinskikh, I. N., Ilyinskikh, E. N., Johansen, Keld, Stavnsbjerg, Peter, Gabrielsson, Pär, Bak, Flemming, Andersen, Erik, Autrup, Herman, Kamens, Richard, Jang, Myoseon, Strommen, Michael, Leach, Keri, Kirchner, U., Scheer, V., Börensen, C., Vogt, R., Igor, Komov, Svjatoslav, Galiy, Anatoliy, Burlak, Komov, I. L., Istchenko, A. A., Lourenço, M. G., MacTavish, D., Sirois, A., Masclet, Pierre, Jaffrezo, Jean Luc, van der Meulen, A., Milukaite, A., Morkunas, V., Jurgutis, P., Mikelinskiene, A., Nielsen, Torben, Feilberg, Anders, Binderup, Mona Lise, Pineda, M., Palacios, J. M., Garcia, E., Cilleruelo, C., Moliner, R., Popovitcheva, O. B., Trukhin, M. E., Persiantseva, N. M., Buriko, Yu, Starik, A. M., Demirdjian, B., Suzanne, J., Probst, T. U., Rietz, B., Alfassi, Z. B., Pokrovskiy, V. A., Zenobi, R., Bogatyr’ov, V. M., Gun’ko, V. M., Querol, X., Alastuey, A., Lopez-Soler, A., Mantilla, E., Plana, F., Artiño, B., Rauterberg-Wulff, A., Israël, G. W., Rocha, Teresa A. P., Duarte, Armando C., Röhrl, Andreas, Lammel, Gerhard, Spindler, G., Müller, K., Herrmann, H., Strommen, Michael R., Vignati, Elisabetta, de Leeuw, Gerrit, and Berkowicz, Ruwim
- Published
- 1998
- Full Text
- View/download PDF
35. A Study of Ozone Laminae Using Diabatic Trajectories, Contour Advection and Photochemical Trajectory Model Simulations.
- Author
-
Reid, S. J., Rex, M., Von Der Gathen, P., Fløisand, I., Stordal, F., Carver, G. D., Beck, A., Reimer, E., Krüger-Carstensen, R., De Haan, L. L., Braathen, G., Dorokhov, V., Fast, H., Kyrö, E., Gil, M., Lityñska, Z., Molyneux, M., Murphy, G., O'Connor, F., Ravegnani, F., Varotsos, C., Wenger, J., and Zerefos, C.
- Published
- 1998
- Full Text
- View/download PDF
36. Long-range Single Molecule F��rster Resonance Energy Transfer Between Alexa Dyes in Zero-Mode Waveguides
- Author
-
Baibakov, Mikhail, Patra, Satyajit, Claude, Jean-Beno��t, and Wenger, J��r��me
- Subjects
Biological Physics (physics.bio-ph) ,FOS: Physical sciences ,Optics (physics.optics) - Abstract
Zero-mode waveguides (ZMW) nanoapertures milled in metal films were proposed to improve the FRET efficiency and enable single molecule FRET detection beyond the 10 nm barrier, overcoming the restrictions of diffraction-limited detection in a homogeneous medium. However, the earlier ZMW demonstrations were limited to the Atto 550 - Atto 647N fluorophore pair, asking the question whether the FRET enhancement observation was an artefact related to this specific set of fluorescent dyes. Here, we use Alexa Fluor 546 and Alexa Fluor 647 to investigate single molecule FRET at large donor-acceptor separations exceeding 10 nm inside ZMWs. These Alexa fluorescent dyes feature a markedly different chemical structure, surface charge and hydrophobicity as compared to their Atto counterparts. Our single molecule data on Alexa 546 - Alexa 647 demonstrate enhanced FRET efficiencies at large separations exceeding 10 nm, extending the spatial range available for FRET and confirming the earlier conclusions. By showing that the FRET enhancement inside a ZMW does not depend on the set of fluorescent dyes, this report is an important step to establish the relevance of ZMWs to extend the sensitivity and detection range of FRET, while preserving its ability to work on regular fluorescent dye pairs.
- Published
- 2020
- Full Text
- View/download PDF
37. Ultraviolet Photostability Improvement for Autofluorescence Correlation Spectroscopy on Label-Free Proteins
- Author
-
Barulin, Aleksandr and Wenger, J��r��me
- Subjects
Chemical Physics (physics.chem-ph) ,Biological Physics (physics.bio-ph) ,FOS: Physical sciences - Abstract
The poor photostability and low brightness of protein autofluorescence have been major limitations preventing the detection of label-free proteins at the single molecule level. Overcoming these issues, we report here a strategy to promote the photostability of proteins and use their natural tryptophan autofluorescence in the ultraviolet (UV) for fluorescence correlation spectroscopy (FCS). Combining enzymatic oxygen scavengers with antioxidants and triplet state quenchers greatly promotes the protein photostability, reduces the photobleaching probability and improves the net autofluorescence detection rate. Our results show that the underlying photochemical concepts initially derived for organic visible fluorescent dyes are quite general. Using this approach, we achieved UV fluorescence correlation spectroscopy on label-free streptavidin proteins containing only 24 tryptophan residues, 6.5x less than the current state-of-the-art. This strategy greatly extends the possibility to detect single label-free proteins with the versatility of single molecule fluorescence without requiring the presence of a potentially disturbing external fluorescent marker. It also opens new perspectives to improve the UV durability of organic devices.
- Published
- 2020
- Full Text
- View/download PDF
38. What kind of learning?
- Author
-
Wenger, J. and Arohanui-Grace
- Published
- 2008
39. Extending Single Molecule F��rster Resonance Energy Transfer (FRET) Range Beyond 10 Nanometers in Zero-Mode Waveguides
- Author
-
Baibakov, Mikhail, Patra, Satyajit, Claude, Jean-Beno��t, Moreau, Antonin, Lumeau, Julien, and Wenger, J��r��me
- Subjects
Chemical Physics (physics.chem-ph) ,Biological Physics (physics.bio-ph) ,FOS: Physical sciences ,Optics (physics.optics) - Abstract
Single molecule F��rster resonance energy transfer (smFRET) is widely used to monitor conformations and interactions dynamics at the molecular level. However, conventional smFRET measurements are ineffective at donor-acceptor distances exceeding 10 nm, impeding the studies on biomolecules of larger size. Here, we show that zero-mode waveguide (ZMW) apertures can be used to overcome the 10 nm barrier in smFRET. Using an optimized ZMW structure, we demonstrate smFRET between standard commercial fluorophores up to 13.6 nm distance with a significantly improved FRET efficiency. To further break into the classical FRET range limit, ZMWs are combined with molecular constructs featuring multiple acceptor dyes to achieve high FRET efficiencies together with high fluorescence count rates. As we discuss general guidelines for quantitative smFRET measurements inside ZMWs, the technique can be readily applied for monitoring conformations and interactions on large molecular complexes with enhanced brightness.
- Published
- 2019
- Full Text
- View/download PDF
40. High-resolution multimodal flexible coherent Raman endoscope
- Author
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Lombardini, Alberto, Mytskaniuk, Vasyl, Sivankutty, Siddharth, Andresen, Esben Ravn, Chen, Xueqin, Wenger, J��r��me, Fabert, Marc, Joly, Nicolas, Louradour, Fr��d��ric, Kudlinski, Alexandre, and Rigneault, Herv��
- Subjects
lcsh:Applied optics. Photonics ,FOS: Physical sciences ,lcsh:TA1501-1820 ,lcsh:QC350-467 ,Medical Physics (physics.med-ph) ,Physics - Medical Physics ,lcsh:Optics. Light ,Article ,Optics (physics.optics) ,Physics - Optics - Abstract
Coherent Raman scattering microscopy is a fast, label-free, and chemically specific imaging technique that shows high potential for future in vivo optical histology. However, the imaging depth in tissues is limited to the sub-millimeter range because of absorption and scattering. Realization of coherent Raman imaging using a fiber endoscope system is a crucial step towards imaging deep inside living tissues and providing information that is inaccessible with current microscopy tools. Until now, the development of coherent Raman endoscopy has been hampered by several issues, mainly related to the fiber delivery of the excitation pulses and signal collection. Here, we present a flexible, compact, coherent Raman, and multimodal nonlinear endoscope (4.2 mm outer diameter, 71 mm rigid length) based on a resonantly scanned hollow-core Kagomé-lattice double-clad fiber. The fiber design enables distortion-less, background-free delivery of femtosecond excitation pulses and back-collection of nonlinear signals through the same fiber. Sub-micrometer spatial resolution over a large field of view is obtained by combination of a miniature objective lens with a silica microsphere lens inserted into the fiber core. We demonstrate high-resolution, high-contrast coherent anti-Stokes Raman scattering, and second harmonic generation endoscopic imaging of biological tissues over a field of view of 320 µm at a rate of 0.8 frames per second. These results pave the way for intraoperative label-free imaging applied to real-time histopathology diagnosis and surgery guidance., Endoscopy: Bringing coherent Raman microscopy into the body A powerful technique called coherent Raman scattering microscopy could be used to visualize and study tissue inside the body thanks to a new light-transmitting fiber technology. Coherent Raman scattering generates images based on the interaction of light with molecules. It opens a window into cells and tissues that reveals information unavailable with simple illumination by light. Applying the technique deep within the body has proved difficult due to technical problems in delivering the necessary ultra-short pulses of light, and collecting the signals that are scattered back. Researchers in France and Germany, led by Hervé Rigneault at the Fresnel Institute in France, combined several innovations in fiber technology to bring high-resolution coherent Raman imaging into previously hidden locations. Their flexible endoscope literally shines new light to assist the diagnosis and surgical treatment of cancer and other diseases.
- Published
- 2018
41. Bacterial meningitis in the United States
- Author
-
Schuchat, A, Robinson, K, Wenger, J D, Harrison, L H, Farley, M, and Reingold, A
- Published
- 1998
42. Synthesis of the New Graminicide Propaquizafop
- Author
-
Klaus, R., primary, Kreienbühl, P., additional, Schnurrenberger, P., additional, Wenger, J., additional, and Winternitz, P., additional
- Published
- 1991
- Full Text
- View/download PDF
43. Meningococcal vaccine in sub-Saharan Africa
- Author
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Wenger, J, Tikhomirov, E, Barakamfitiye, D, Bele, Okwe, and Heymann, David L
- Published
- 1997
44. Laser-induced fluorescence quenching of red fluorescent dyes with green excitation: avoiding artifacts in PIE-FRET and FCCS analysis
- Author
-
Baibakov, Mikhail and Wenger, J��r��me
- Subjects
Chemical Physics (physics.chem-ph) ,FOS: Physical sciences ,Optics (physics.optics) - Abstract
Multicolor excitation is at the core of many fluorescence spectroscopy techniques such as PIE-FRET, ALEX-FRET, or FCCS. However, the influence of the multiple laser excitations on the dye photophysics is often overlooked. Here, we show that green laser pulses can surprisingly quench the fluorescence of common red dyes Alexa Fluor 647 and Atto 647N, even when the conditions leading to photobleaching are avoided. The physical origin of this phenomenon is discussed via a long-lived dark state and/or photorefractive effects. These observations are important to avoid measurement artifacts as both the fluorophore concentration and the fluorescence brightness are affected.
- Published
- 2018
- Full Text
- View/download PDF
45. Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions
- Author
-
Eibl, C., Hessenberger, M., Wenger, J., and Brandstetter, H.
- Subjects
Sequence Homology, Amino Acid ,Protein Conformation ,Circular Dichroism ,fungi ,Molecular Sequence Data ,Pyrin ,Nucleoside-Triphosphatase ,Research Papers ,NLRP14 ,Cytoskeletal Proteins ,Chromatography, Gel ,Humans ,pyrin domain ,Amino Acid Sequence - Abstract
Pyrin domains (PYDs) recruit downstream effector molecules in NLR signalling. A specific charge-relay system suggests a the formation of a signalling complex involving a PYD dimer., The cytosolic tripartite NLR receptors serve as important signalling platforms in innate immunity. While the C-terminal domains act as sensor and activation modules, the N-terminal death-like domain, e.g. the CARD or pyrin domain, is thought to recruit downstream effector molecules by homotypic interactions. Such homotypic complexes have been determined for all members of the death-domain superfamily except for pyrin domains. Here, crystal structures of human NLRP14 pyrin-domain variants are reported. The wild-type protein as well as the clinical D86V mutant reveal an unexpected rearrangement of the C-terminal helix α6, resulting in an extended α5/6 stem-helix. This reordering mediates a novel symmetric pyrin-domain dimerization mode. The conformational switching is controlled by a charge-relay system with a drastic impact on protein stability. How the identified charge relay allows classification of NLRP receptors with respect to distinct recruitment mechanisms is discussed.
- Published
- 2014
46. The raid through Japanese eyes
- Author
-
Goldstein, Donald M., Dillon, Katherine V., and Wenger, J. Michael
- Subjects
Pearl Harbor Attack, 1941 -- History ,Bombings -- Portrayals ,Aircraft carriers -- Portrayals ,Navies -- Portrayals ,Japan -- History - Published
- 1991
47. Planar millimeter-wave antennas using SiNx-membranes on GaAs
- Author
-
Stotz, M., Gottwald, G., Haspeklo, H., and Wenger, J.
- Subjects
Millimeter wave communication systems -- Research ,Microwave antennas -- Research ,Business ,Computers ,Electronics ,Electronics and electrical industries - Abstract
Planar aperture coupled microstrip antennas for 77 GHz are demonstrated for the first time. As far as possible standard GaAs monolithic microwave/millimeter-wave integrated circuit (MMIC) technology is used to realize the antennas. The antenna patches are suspended on a thin dielectric Si[N.sub.x] membrane on GaAs substrate. Therefore a novel plasma-enhanced chemical vapor deposition (PECVD) process step for the fabrication of the membranes is developed and described. The single antenna patches are coupled to a microstrip line through an aperture in the ground metallization. The method of moments in spectral domain is applied to design the patches. The feed network of a 3 x 1 antenna array for homogeneous excitation is simulated and optimized with a microwave design system (MDS). From reflection measurements the operation frequency of this triple patch antenna is determined to be 77.6 GHz. The farfield antenna characteristics are measured in an anechoic chamber, showing good agreement between simulated and measured results and a co- to cross-polarization isolation better than 30 dB.
- Published
- 1996
48. Is Enlisted Retention too High?
- Author
-
Hansen, M. L., primary and Wenger, J. W., primary
- Published
- 2003
- Full Text
- View/download PDF
49. Does Education Reform Improve Job Performance
- Author
-
Wenger, J. W., primary, Lien, D. D., primary, and Cavalluzzo, L. C., primary
- Published
- 2003
- Full Text
- View/download PDF
50. Incidence and Clinical Characteristics of Invasive Haemophilus influenzae Disease in Adults
- Author
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CDC Meningitis Surveillance Group, Farley, M. M., Stephens, D. S., Harvey, R. C., Sikes, R. K., and Wenger, J. D.
- Published
- 1992
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