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1. Impact of magnetic resonance-guided versus conventional radiotherapy workflows on organ at risk doses in stereotactic body radiotherapy for lymph node oligometastases

Author

Werensteijn-Honingh, Anita M., Kroon, Petra S., Winkel, Dennis, van Gaal, J. Carlijn, Hes, Jochem, Snoeren, Louk M.W., Timmer, Jaleesa K., Mout, Christiaan C.P., Bol, Gijsbert H., Kotte, Alexis N., Eppinga, Wietse S.C., Intven, Martijn, Raaymakers, Bas W., and Jürgenliemk-Schulz, Ina M.

Published
2022
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5. Target coverage and dose criteria based evaluation of the first clinical 1.5T MR-linac SBRT treatments of lymph node oligometastases compared with conventional CBCT-linac treatment

Author

Winkel, Dennis, Bol, Gijsbert H., Werensteijn-Honingh, Anita M., Intven, Martijn P.W., Eppinga, Wietse S.C., Hes, Jochem, Snoeren, Louk M.W., Sikkes, Gonda G., Gadellaa-van Hooijdonk, Christa G.M., Raaymakers, Bas W., Jürgenliemk-Schulz, Ina M., and Kroon, Petra S.

Published
2020
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6. Individual lymph nodes: “See it and Zap it”

Author

Winkel, Dennis, Werensteijn-Honingh, Anita M., Kroon, Petra S., Eppinga, Wietse S.C., Bol, Gijsbert H., Intven, Martijn P.W., de Boer, Hans C.J., Snoeren, Louk M.W., Hes, Jochem, Raaymakers, Bas W., and Jürgenliemk-Schulz, Ina M.

Published
2019
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7. Adaptive radiotherapy: The Elekta Unity MR-linac concept

Author

Winkel, Dennis, Bol, Gijsbert H., Kroon, Petra S., van Asselen, Bram, Hackett, Sara S., Werensteijn-Honingh, Anita M., Intven, Martijn P.W., Eppinga, Wietse S.C., Tijssen, Rob H.N., Kerkmeijer, Linda G.W., de Boer, Hans C.J., Mook, Stella, Meijer, Gert J., Hes, Jochem, Willemsen-Bosman, Mirjam, de Groot-van Breugel, Eline N., Jürgenliemk-Schulz, Ina M., and Raaymakers, Bas W.

Published
2019
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10. Impact of magnetic resonance-guided versus conventional radiotherapy workflows on organ at risk doses in stereotactic body radiotherapy for lymph node oligometastases

Author

Cancer, Klinische Fysica RT, Experimentele klinische fysica, Arts-assistenten Radiotherapie, MS Radiotherapie, Werensteijn-Honingh, Anita M, Kroon, Petra S, Winkel, Dennis, van Gaal, J Carlijn, Hes, Jochem, Snoeren, Louk M W, Timmer, Jaleesa K, Mout, Christiaan C P, Bol, Gijsbert H, Kotte, Alexis N, Eppinga, Wietse S C, Intven, Martijn, Raaymakers, Bas W, Jürgenliemk-Schulz, Ina M, Cancer, Klinische Fysica RT, Experimentele klinische fysica, Arts-assistenten Radiotherapie, MS Radiotherapie, Werensteijn-Honingh, Anita M, Kroon, Petra S, Winkel, Dennis, van Gaal, J Carlijn, Hes, Jochem, Snoeren, Louk M W, Timmer, Jaleesa K, Mout, Christiaan C P, Bol, Gijsbert H, Kotte, Alexis N, Eppinga, Wietse S C, Intven, Martijn, Raaymakers, Bas W, and Jürgenliemk-Schulz, Ina M

Published
2022

12. Comparison of Library of Plans with two daily adaptive strategies for whole bladder radiotherapy

Author

Radiotherapie, Klinische Fysica RT, Cancer, MS Radiotherapie, Arts-assistenten Radiotherapie, Onderzoek Radiotherapie, den Boer, Duncan, den Hartogh, Mariska D., Kotte, Alexis N.T.J., van der Voort van Zyp, Jochem R.N., Noteboom, Juus L., Bol, Gijsbert H., Willigenburg, Thomas, Werensteijn-Honingh, Anita M., Jürgenliemk-Schulz, Ina M., van Lier, Astrid L.H.M.W., Kroon, Petra S., Radiotherapie, Klinische Fysica RT, Cancer, MS Radiotherapie, Arts-assistenten Radiotherapie, Onderzoek Radiotherapie, den Boer, Duncan, den Hartogh, Mariska D., Kotte, Alexis N.T.J., van der Voort van Zyp, Jochem R.N., Noteboom, Juus L., Bol, Gijsbert H., Willigenburg, Thomas, Werensteijn-Honingh, Anita M., Jürgenliemk-Schulz, Ina M., van Lier, Astrid L.H.M.W., and Kroon, Petra S.

Published
2021

13. Progression-free survival in patients with Ga-68-PSMA-PET-directed SBRT for lymph node oligometastases

Author

Onderzoek Radiotherapie, Cancer, Arts-assistenten Radiotherapie, Klinische Fysica RT, MS Radiotherapie, Werensteijn-Honingh, Anita M, Wevers, Anne F J, Peters, Max, Kroon, Petra S, Intven, Martijn, Eppinga, Wietse S C, Jürgenliemk-Schulz, Ina M, Onderzoek Radiotherapie, Cancer, Arts-assistenten Radiotherapie, Klinische Fysica RT, MS Radiotherapie, Werensteijn-Honingh, Anita M, Wevers, Anne F J, Peters, Max, Kroon, Petra S, Intven, Martijn, Eppinga, Wietse S C, and Jürgenliemk-Schulz, Ina M

Published
2021

14. Impact of a vacuum cushion on intrafraction motion during online adaptive MR-guided SBRT for pelvic and para-aortic lymph node oligometastases

Author

Onderzoek Radiotherapie, Cancer, MS Radiotherapie, Arts-assistenten Radiotherapie, Experimentele klinische fysica, Klinische Fysica RT, Werensteijn-Honingh, Anita M, Jürgenliemk-Schulz, Ina M, Gadellaa-Van Hooijdonk, Christa G, Sikkes, Gonda G, Vissers, Nicole G P M, Winkel, Dennis, Eppinga, Wietse S C, Intven, Martijn, Raaymakers, Bas W, Kroon, Petra S, Onderzoek Radiotherapie, Cancer, MS Radiotherapie, Arts-assistenten Radiotherapie, Experimentele klinische fysica, Klinische Fysica RT, Werensteijn-Honingh, Anita M, Jürgenliemk-Schulz, Ina M, Gadellaa-Van Hooijdonk, Christa G, Sikkes, Gonda G, Vissers, Nicole G P M, Winkel, Dennis, Eppinga, Wietse S C, Intven, Martijn, Raaymakers, Bas W, and Kroon, Petra S

Published
2021

15. Feasibility of stereotactic radiotherapy using a 1.5 T MR-linac: Multi-fraction treatment of pelvic lymph node oligometastases

Author

Werensteijn-Honingh, Anita M., Kroon, Petra S., Winkel, Dennis, Aalbers, Ellart M., van Asselen, Bram, Bol, Gijsbert H., Brown, Kevin J., Eppinga, Wietse S.C., van Es, Corine A., Glitzner, Markus, de Groot-van Breugel, Eline N., Hackett, Sara L., Intven, Martijn, Kok, Jan G.M., Kontaxis, Charis, Kotte, Alexis N., Lagendijk, Jan J.W., Philippens, Mariëlle E.P., Tijssen, Rob H.N., Wolthaus, Jochem W.H., Woodings, Simon J., Raaymakers, Bas W., and Jürgenliemk-Schulz, Ina M.

Published
2019
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16. Target coverage and dose criteria based evaluation of the first clinical 1.5T MR-linac SBRT treatments of lymph node oligometastases compared with conventional CBCT-linac treatment

Author

ICT RT, Experimentele klinische fysica, Klinische Fysica RT, Cancer, Onderzoek Radiotherapie, MS Radiotherapie, Arts-assistenten Radiotherapie, Winkel, Dennis, Bol, Gijsbert H., Werensteijn-Honingh, Anita M., Intven, Martijn P.W., Eppinga, Wietse S.C., Hes, Jochem, Snoeren, Louk M.W., Sikkes, Gonda G., Gadellaa-van Hooijdonk, Christa G.M., Raaymakers, Bas W., Jürgenliemk-Schulz, Ina M., Kroon, Petra S., ICT RT, Experimentele klinische fysica, Klinische Fysica RT, Cancer, Onderzoek Radiotherapie, MS Radiotherapie, Arts-assistenten Radiotherapie, Winkel, Dennis, Bol, Gijsbert H., Werensteijn-Honingh, Anita M., Intven, Martijn P.W., Eppinga, Wietse S.C., Hes, Jochem, Snoeren, Louk M.W., Sikkes, Gonda G., Gadellaa-van Hooijdonk, Christa G.M., Raaymakers, Bas W., Jürgenliemk-Schulz, Ina M., and Kroon, Petra S.

Published
2020

17. Progression-free survival in patients with 68Ga-PSMA-PET-directed SBRT for lymph node oligometastases.

Author

Werensteijn-Honingh, Anita M., Wevers, Anne F. J., Peters, Max, Kroon, Petra S., Intven, Martijn, Eppinga, Wietse S. C., and Jürgenliemk-Schulz, Ina M.

Subjects
*DISEASE progression, *CONFIDENCE intervals, *MULTIVARIATE analysis, *AGE distribution, *METASTASIS, *TREATMENT effectiveness, *CANCER patients, *RISK assessment, *DESCRIPTIVE statistics, *CANCER fatigue, *QUALITY of life, *LYMPHOMAS, *RADIOSURGERY, *PROSTATE-specific antigen, *PROSTATE tumors, *LONGITUDINAL method
Abstract

Prostate cancer oligometastatic disease can be treated using stereotactic body radiotherapy (SBRT) in order to postpone start of systemic treatments such as androgen deprivation therapy (ADT). 68Ga-PSMA-PET/CT imaging allows for diagnosis of oligometastases at lower PSA values. We analysed a cohort of patients with prostate cancer lymph node oligometastases detected on PSMA-PET/CT. Ninety patients with metachronous oligometastatic prostate cancer received SBRT for 1–3 lymph node metastases diagnosed on 68Ga-PSMA-PET/CT. The primary end point was progression free survival (PFS), with disease progression defined as occurrence of either target lesion progression, new metastatic lesion or biochemical progression. Secondary outcomes were biochemical PFS (BPFS), ADT-free survival (ADT-FS), toxicity and quality of life (QoL). Baseline patient characteristics were tested for association with PFS and a preliminary risk score was created. Median follow-up was 21 months (interquartile range 10–31 months). Median PFS and BPFS were 16 and 21 months, respectively. Median ADT-FS was not reached (73% (95%-CI 62–86%) at 24 months). In multivariable analysis, younger age, higher PSA prior to SBRT and extrapelvic location were associated with shorter PFS. Grade 1 fatigue was the most predominant acute toxicity (34%). Highest grade toxicity was grade 2 for acute and late events. QoL analysis showed mild, transient increase in fatigue at 1–4 weeks after SBRT. A median PFS of 16 months was attained after SBRT for patients with PSMA-PET positive oligometastatic lymph nodes from prostate cancer. Higher pre-SBRT PSA, younger age and extrapelvic location were found to be predictors of shorter PFS. [ABSTRACT FROM AUTHOR]

Published
2021
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18. Feasibility of stereotactic radiotherapy using a 1.5 T MR-linac : Multi-fraction treatment of pelvic lymph node oligometastases

Author

Werensteijn-Honingh, Anita M, Kroon, Petra S, Winkel, Dennis, Aalbers, Ellart M, van Asselen, Bram, Bol, Gijsbert H, Brown, Kevin J, Eppinga, Wietse S C, van Es, Corine A, Glitzner, Markus, de Groot-van Breugel, Eline N, Hackett, Sara L, Intven, Martijn, Kok, Jan G M, Kontaxis, Charis, Kotte, Alexis N, Lagendijk, Jan J W, Philippens, Mariëlle E P, Tijssen, Rob H N, Wolthaus, Jochem W H, Woodings, Simon J, Raaymakers, Bas W, Jürgenliemk-Schulz, Ina M, Werensteijn-Honingh, Anita M, Kroon, Petra S, Winkel, Dennis, Aalbers, Ellart M, van Asselen, Bram, Bol, Gijsbert H, Brown, Kevin J, Eppinga, Wietse S C, van Es, Corine A, Glitzner, Markus, de Groot-van Breugel, Eline N, Hackett, Sara L, Intven, Martijn, Kok, Jan G M, Kontaxis, Charis, Kotte, Alexis N, Lagendijk, Jan J W, Philippens, Mariëlle E P, Tijssen, Rob H N, Wolthaus, Jochem W H, Woodings, Simon J, Raaymakers, Bas W, and Jürgenliemk-Schulz, Ina M

Published
2019

19. Individual lymph nodes: 'See it and Zap it'

Author

Cancer, Onderzoek Radiotherapie, Klinische Fysica RT, MS Radiotherapie, Experimentele klinische fysica, Winkel, Dennis, Werensteijn-Honingh, Anita M, Kroon, Petra S, Eppinga, Wietse S C, Bol, Gijsbert H, Intven, Martijn P W, de Boer, Hans C J, Snoeren, Louk M W, Hes, Jochem, Raaymakers, Bas W, Jürgenliemk-Schulz, Ina M, Cancer, Onderzoek Radiotherapie, Klinische Fysica RT, MS Radiotherapie, Experimentele klinische fysica, Winkel, Dennis, Werensteijn-Honingh, Anita M, Kroon, Petra S, Eppinga, Wietse S C, Bol, Gijsbert H, Intven, Martijn P W, de Boer, Hans C J, Snoeren, Louk M W, Hes, Jochem, Raaymakers, Bas W, and Jürgenliemk-Schulz, Ina M

Published
2019

20. Evaluation of plan adaptation strategies for stereotactic radiotherapy of lymph node oligometastases using online magnetic resonance image guidance

Author

Cancer, Fysica Radiotherapie Research, Klinische Fysica RT, Arts-assistenten Radiotherapie, Onderzoek Radiotherapie, MS Radiotherapie, Experimentele klinische fysica, Winkel, Dennis, Bol, Gijsbert H., Werensteijn-Honingh, Anita M., Kiekebosch, Ilse H., van Asselen, Bram, Intven, Martijn P.W., Eppinga, Wietse S.C., Raaymakers, Bas W., Jürgenliemk-Schulz, Ina M., Kroon, Petra S., Cancer, Fysica Radiotherapie Research, Klinische Fysica RT, Arts-assistenten Radiotherapie, Onderzoek Radiotherapie, MS Radiotherapie, Experimentele klinische fysica, Winkel, Dennis, Bol, Gijsbert H., Werensteijn-Honingh, Anita M., Kiekebosch, Ilse H., van Asselen, Bram, Intven, Martijn P.W., Eppinga, Wietse S.C., Raaymakers, Bas W., Jürgenliemk-Schulz, Ina M., and Kroon, Petra S.

Published
2019

21. Feasibility of stereotactic radiotherapy using a 1.5 T MR-linac: Multi-fraction treatment of pelvic lymph node oligometastases

Author

Onderzoek Radiotherapie, Cancer, Klinische Fysica RT, MS Radiotherapie, Fysica Radiotherapie Research, Experimentele klinische fysica, Werensteijn-Honingh, Anita M, Kroon, Petra S, Winkel, Dennis, Aalbers, Ellart M, van Asselen, Bram, Bol, Gijsbert H, Brown, Kevin J, Eppinga, Wietse S C, van Es, Corine A, Glitzner, Markus, de Groot-van Breugel, Eline N, Hackett, Sara L, Intven, Martijn, Kok, Jan G M, Kontaxis, Charis, Kotte, Alexis N, Lagendijk, Jan J W, Philippens, Mariëlle E P, Tijssen, Rob H N, Wolthaus, Jochem W H, Woodings, Simon J, Raaymakers, Bas W, Jürgenliemk-Schulz, Ina M, Onderzoek Radiotherapie, Cancer, Klinische Fysica RT, MS Radiotherapie, Fysica Radiotherapie Research, Experimentele klinische fysica, Werensteijn-Honingh, Anita M, Kroon, Petra S, Winkel, Dennis, Aalbers, Ellart M, van Asselen, Bram, Bol, Gijsbert H, Brown, Kevin J, Eppinga, Wietse S C, van Es, Corine A, Glitzner, Markus, de Groot-van Breugel, Eline N, Hackett, Sara L, Intven, Martijn, Kok, Jan G M, Kontaxis, Charis, Kotte, Alexis N, Lagendijk, Jan J W, Philippens, Mariëlle E P, Tijssen, Rob H N, Wolthaus, Jochem W H, Woodings, Simon J, Raaymakers, Bas W, and Jürgenliemk-Schulz, Ina M

Published
2019

22. Adaptive radiotherapy: The Elekta Unity MR-linac concept

Author

Cancer, Fysica Radiotherapie Research, Klinische Fysica RT, Onderzoek Radiotherapie, MS Radiotherapie, Experimentele klinische fysica, Winkel, Dennis, Bol, Gijsbert H, Kroon, Petra S, van Asselen, Bram, Hackett, Sara S, Werensteijn-Honingh, Anita M, Intven, Martijn P W, Eppinga, Wietse S C, Tijssen, Rob H N, Kerkmeijer, Linda G W, de Boer, Hans C J, Mook, Stella, Meijer, Gert J, Hes, Jochem, Willemsen-Bosman, Mirjam, de Groot-van Breugel, Eline N, Jürgenliemk-Schulz, Ina M, Raaymakers, Bas W, Cancer, Fysica Radiotherapie Research, Klinische Fysica RT, Onderzoek Radiotherapie, MS Radiotherapie, Experimentele klinische fysica, Winkel, Dennis, Bol, Gijsbert H, Kroon, Petra S, van Asselen, Bram, Hackett, Sara S, Werensteijn-Honingh, Anita M, Intven, Martijn P W, Eppinga, Wietse S C, Tijssen, Rob H N, Kerkmeijer, Linda G W, de Boer, Hans C J, Mook, Stella, Meijer, Gert J, Hes, Jochem, Willemsen-Bosman, Mirjam, de Groot-van Breugel, Eline N, Jürgenliemk-Schulz, Ina M, and Raaymakers, Bas W

Published
2019

23. Cervical cancer apparent diffusion coefficient values during external beam radiotherapy

Author

Arts-assistenten Radiotherapie, Computational Imaging, Circulatory Health, Cancer, Onderzoek Radiotherapie, Klinische Fysica RT, MS Radiotherapie, de Boer, Peter, Mandija, Stefano, Werensteijn-Honingh, Anita M., van den Berg, Cornelis A.T., de Leeuw, Astrid A.C., Jürgenliemk-Schulz, Ina M., Arts-assistenten Radiotherapie, Computational Imaging, Circulatory Health, Cancer, Onderzoek Radiotherapie, Klinische Fysica RT, MS Radiotherapie, de Boer, Peter, Mandija, Stefano, Werensteijn-Honingh, Anita M., van den Berg, Cornelis A.T., de Leeuw, Astrid A.C., and Jürgenliemk-Schulz, Ina M.

Published
2019

26. Simulated dosimetric impact of online replanning for stereotactic body radiation therapy of lymph node oligometastases on the 1.5T MR-linac

Author

Cancer, Klinische Fysica RT, Onderzoek Radiotherapie, Experimentele klinische fysica, MS Radiotherapie, Winkel, Dennis, Kroon, Petra S, Werensteijn-Honingh, Anita M, Bol, Gijsbert H, Raaymakers, Bas W, Jürgenliemk-Schulz, Ina M, Cancer, Klinische Fysica RT, Onderzoek Radiotherapie, Experimentele klinische fysica, MS Radiotherapie, Winkel, Dennis, Kroon, Petra S, Werensteijn-Honingh, Anita M, Bol, Gijsbert H, Raaymakers, Bas W, and Jürgenliemk-Schulz, Ina M

Published
2018

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