496 results on '"Whitaker, K"'
Search Results
2. The ALMA-ALPAKA survey II. Evolution of turbulence in galaxy disks across cosmic time: difference between cold and warm gas
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Rizzo, F., Bacchini, C., Kohandel, M., Di Mascolo, L., Fraternali, F., Roman-Oliveira, F., Zanella, A., Popping, G., Valentino, F., Magdis, G., and Whitaker, K.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
The gas in the interstellar medium (ISM) of galaxies is supersonically turbulent. Measurements of turbulence typically rely on cold gas emission lines for low-z galaxies and warm ionized gas observations for z>0 galaxies. Studies of warm gas kinematics at z>0 conclude that the turbulence strongly evolves as a function of redshift, due to the increasing impact of gas accretion and mergers in the early Universe. However, recent findings suggest potential biases in turbulence measurements derived from ionized gas at high-z, impacting our understanding of turbulence origin, ISM physics and disk formation. We investigate the evolution of turbulence using velocity dispersion ($\sigma$) measurements from cold gas tracers (i.e., CO, [CI], [CII]) derived from a sample of 57 galaxy disks spanning the redshift range z=0-5. This sample consists of main-sequence and starburst galaxies with stellar masses $\gtrsim 10^{10} M_{\odot}$. The comparison with current H$\alpha$ kinematic observations and existing models demonstrates that the velocity dispersion inferred from cold gas tracers differ by a factor of $\approx 3$ from those obtained using emission lines tracing warm gas. We show that stellar feedback is the main driver of turbulence measured from cold gas tracers. This is fundamentally different from the conclusions of studies based on warm gas, which had to consider additional turbulence drivers to explain the high values of $\sigma$. We present a model predicting the redshift evolution of turbulence in galaxy disks, attributing the increase of $\sigma$ with redshift to the higher energy injected by supernovae due to the elevated star-formation rate in high-z galaxies. This supernova-driven model suggests that turbulence is lower in galaxies with lower stellar mass compared to those with higher stellar mass. Additionally, it forecasts the evolution of $\sigma$ in Milky-Way like progenitors., Comment: Accepted for publication in A&A. The abstract has been modified to comply with arXiv's character limit
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- 2024
- Full Text
- View/download PDF
3. Performance of the HAWC Observatory and TeV Gamma-Ray Measurements of the Crab Nebula with Improved Extensive Air Shower Reconstruction Algorithms
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Albert, A ., Alfaro, R., Alvarez, C., Andrés, A ., Arteaga-Velázquez, J. C., Rojas, D. Avila, Solares, H. A. Ayala, Babu, R., Belmont-Moreno, E., Caballero-Mora, K. S., Capistrán, T., Carramiñana, A., Casanova, S., Cotti, U., Cotzomi, J., de León, S. Coutiño, De la Fuente, E., de León, C., Depaoli, D., Di Lalla, N., Hernandez, R. Diaz, Dingus, B. L ., DuVernois, M. A., Engel, K., Ergin, T., Espinoza, C ., Fan, K. L., Fang, K., Fraija, N., Fraija, S., García-González, J. A., Garfias, F., Goksu, H ., González, M. M., Goodman, J. A., Groetsch, S., Harding, J. P., Hernández-Cadena, S., Herzog, I., Hinton, J ., Huang, D., Hueyotl-Zahuantitla, F., Hüntemeyer, P., Iriarte, A., Kaufmann, S., Lara, A ., Lee, J., Vargas, H. León, Linnemann, J. T ., Longinotti, A. L., Luis-Raya, G., Malone, K., Martínez-Castro, J., Matthews, J. A., Miranda-Romagnoli, P., Montes, J. A., Moreno, E., Mostafá, M., Nellen, L., Nisa, M. U ., Noriega-Papaqui, R ., Olivera-Nieto, L ., Omodei, N., Osorio, M., Araujo, Y. Pérez, Pérez-Pérez, E. G., Rho, C. D., Rosa-González, D., Ruiz-Velasco, E ., Salazar, H., Salazar-Gallegos, D., Sandoval, A., Schneider, M., Schwefer, G ., Serna-Franco, J., Smith, A. J., Son, Y., Springer, R. W ., Tibolla, O., Tollefson, K., Torres, I., Torres-Escobedo, R., Turner, R., Ureña-Mena, F., Varela, E ., Wang, X., Watson, I. J., Whitaker, K., Willox, E., Wu, H., Yu, S ., Yun-Cárcamo, S., and Zhou, H.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The High-Altitude Water Cherenkov (HAWC) Gamma-Ray Observatory located on the side of the Sierra Negra volcano in Mexico, has been fully operational since 2015. The HAWC collaboration has recently significantly improved their extensive-air-shower reconstruction algorithms, which has notably advanced the observatory performance. The energy resolution for primary gamma rays with energies below 1~TeV was improved by including a noise-suppression algorithm. Corrections have also been made to systematic errors in direction fitting related to the detector and shower plane inclinations, $\mathcal{O}(0.1^{\circ})$ biases in highly inclined showers, as well as enhancements to the core reconstruction. The angular resolution for gamma rays approaching the HAWC array from large zenith angles ($> 37^{\circ}$) has improved by a factor of four at the highest energies ($> 70$~TeV) as compared to previous reconstructions. The inclusion of a lateral distribution function fit to the extensive air shower footprint on the array to separate gamma-ray primaries from cosmic-ray ones, based on the resulting $\chi^{2}$ values, improved the background rejection performance at all inclinations. At large zenith angles, the improvement in significance is a factor of four compared to previous HAWC publications. These enhancements have been verified by observing the Crab Nebula, which is an overhead source for the HAWC Observatory. We show that the sensitivity to Crab-like point sources ($E^{-2.63}$) with locations overhead to 30$^{\circ}$ zenith is comparable or less than 10\% of the Crab Nebula's flux between 2 and 50~TeV. Thanks to these improvements, HAWC can now detect more sources, including the Galactic Center.
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- 2024
4. Search for joint multimessenger signals from potential Galactic PeVatrons with HAWC and IceCube
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Alfaro, R., Alvarez, C., Arteaga-Velázquez, J. C., Rojas, D. Avila, Solares, H. A. Ayala, Babu, R., Belmont-Moreno, E., Caballero-Mora, K. S., Capistrán, T., Carramiñana, A., Casanova, S., Cotti, U., Cotzomi, J., de León, S. Coutiño, De la Fuente, E., Depaoli, D., Di Lalla, N., Hernandez, R. Diaz, Díaz-Vélez, J. C., Engel, K., Ergin, T., Fan, K. L., Fang, K., Fraija, N., Fraija, S., García-González, J. A., Garfias, F., González, M. M., Goodman, J. A., Groetsch, S., Harding, J. P., Hernández-Cadena, S., Herzog, I., Huang, D., Hueyotl-Zahuantitla, F., Hüntemeyer, P., Iriarte, A., Kaufmann, S., Lee, J., Vargas, H. León, Longinotti, A. L., Luis-Raya, G., Malone, K., Martínez-Castro, J., Matthews, J. A., Miranda-Romagnoli, P., Montes, J. A., Moreno, E., Mostafá, M., Nellen, L., Omodei, N., Osorio, M., Araujo, Y. Pérez, Pérez-Pérez, E. G., Rho, C. D., Rosa-González, D., Salazar, H., Salazar-Gallegos, D., Sandoval, A., Schneider, M., Serna-Franco, J., Smith, A. J., Son, Y., Tibolla, O., Tollefson, K., Torres, I., Torres-Escobedo, R., Turner, R., Ureña-Mena, F., Wang, X., Watson, I. J., Whitaker, K., Willox, E., Wu, H., Yun-Cárcamo, S., Zhou, H., de León, C., Abbasi, R., Ackermann, M., Adams, J., Agarwalla, S. K., Aguilar, J. A., Ahlers, M., Alameddine, J. M., Amin, N. M., Andeen, K., Argüelles, C., Ashida, Y., Athanasiadou, S., Ausborm, L., Axani, S. N., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Bash, S., Basu, V., Bay, R., Beatty, J. J., Tjus, J. Becker, Beise, J., Bellenghi, C., Benning, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Blaufuss, E., Bloom, L., Blot, S., Bontempo, F., Motzkin, J. Y. Book, Meneguolo, C. Boscolo, Böser, S., Botner, O., Böttcher, J., Braun, J., Brinson, B., Brostean-Kaiser, J., Brusa, L., Burley, R. T., Butterfield, D., Campana, M. A., Caracas, I., Carloni, K., Carpio, J., Chattopadhyay, S., Chau, N., Chen, Z., Chirkin, D., Choi, S., Clark, B. A., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Corley, R., Correa, P., Cowen, D. F., Dave, P., De Clercq, C., DeLaunay, J. J., Delgado, D., Deng, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Dierichs, P., Dittmer, M., Domi, A., Draper, L., Dujmovic, H., Dutta, K., DuVernois, M. A., Ehrhardt, T., Eidenschink, L., Eimer, A., Eller, P., Ellinger, E., Mentawi, S. El, Elsässer, D., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Farrag, K., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Fukami, S., Fürst, P., Gallagher, J., Ganster, E., Garcia, A., Garcia, M., Garg, G., Genton, E., Gerhardt, L., Ghadimi, A., Girard-Carillo, C., Glaser, C., Glüsenkamp, T., Gonzalez, J. G., Goswami, S., Granados, A., Grant, D., Gray, S. J., Gries, O., Griffin, S., Griswold, S., Groth, K. M., Günther, C., Gutjahr, P., Ha, C., Haack, C., Hallgren, A., Halve, L., Halzen, F., Hamdaoui, H., Minh, M. Ha, Handt, M., Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Häußler, J., Helbing, K., Hellrung, J., Hermannsgabner, J., Heuermann, L., Heyer, N., Hickford, S., Hidvegi, A., Hill, C., Hill, G. C., Hoffman, K. D., Hori, S., Hoshina, K., Hostert, M., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., Ishihara, A., Iwakiri, W., Jacquart, M., Janik, O., Jansson, M., Japaridze, G. S., Jeong, M., Jin, M., Jones, B. J. P., Kamp, N., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katil, A., Katz, U., Kauer, M., Kelley, J. L., Khanal, M., Zathul, A. Khatee, Kheirandish, A., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Krishnamoorthi, J., Kruiswijk, K., Krupczak, E., Kumar, A., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lamoureux, M., Larson, M. J., Latseva, S., Lauber, F., Lazar, J. P., Lee, J. W., DeHolton, K. Leonard, Leszczyńska, A., Liao, J., Lincetto, M., Liu, Y. T., Liubarska, M., Lohfink, E., Love, C., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Luszczak, W., Lyu, Y., Madsen, J., Magnus, E., Mahn, K. B. M., Makino, Y., Manao, E., Mancina, S., Sainte, W. Marie, Mariş, I. C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., Mayhew, F., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Merckx, Y., Merten, L., Micallef, J., Mitchell, J., Montaruli, T., Moore, R. W., Morii, Y., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Nakos, M., Naumann, U., Necker, J., Negi, A., Neste, L., Neumann, M., Niederhausen, H., Noda, K., Noell, A., Novikov, A., Pollmann, A. Obertacke, O'Dell, V., Oeyen, B., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Pandya, H., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Pernice, T., Peterson, J., Philippen, S., Pizzuto, A., Plum, M., Pontén, A., Popovych, Y., Rodriguez, M. Prado, Pries, B., Procter-Murphy, R., Przybylski, G. T., Raab, C., Rack-Helleis, J., Ravn, M., Rawlins, K., Rechav, Z., Rehman, A., Reichherzer, P., Resconi, E., Reusch, S., Rhode, W., Riedel, B., Rifaie, A., Roberts, E. J., Robertson, S., Rodan, S., Roellinghoff, G., Rongen, M., Rosted, A., Rott, C., Ruhe, T., Ruohan, L., Ryckbosch, D., Safa, I., Saffer, J., Sampathkumar, P., Sandrock, A., Santander, M., Sarkar, S., Savelberg, J., Savina, P., Schaile, P., Schaufel, M., Schieler, H., Schindler, S., Schlüter, B., Schlüter, F., Schmeisser, N., Schmidt, T., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seikh, M., Seo, M., Seunarine, S., Myhr, P. Sevle, Shah, R., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Soldin, P., Sommani, G., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Terliuk, A., Thiesmeyer, M., Thompson, W. G., Thwaites, J., Tilav, S., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Turcotte, R., Twagirayezu, J. P., Elorrieta, M. A. Unland, Upadhyay, A. K., Upshaw, K., Vaidyanathan, A., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Veitch-Michaelis, J., Venugopal, M., Vereecken, M., Verpoest, S., Veske, D., Vijai, A., Walck, C., Wang, A., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wen, A. Y., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Williams, D. R., Witthaus, L., Wolf, A., Wolf, M., Wrede, G., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Young, R., Yu, S., Yuan, T., Zhang, Z., Zhelnin, P., Zilberman, P., and Zimmerman, M.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Galactic PeVatrons are sources that can accelerate cosmic rays to PeV energies. The high-energy cosmic rays are expected to interact with the surrounding ambient material or radiation, resulting in the production of gamma rays and neutrinos. To optimize for the detection of such associated production of gamma rays and neutrinos for a given source morphology and spectrum, a multi-messenger analysis that combines gamma rays and neutrinos is required. In this study, we use the Multi-Mission Maximum Likelihood framework (3ML) with IceCube Maximum Likelihood Analysis software (i3mla) and HAWC Accelerated Likelihood (HAL) to search for a correlation between 22 known gamma-ray sources from the third HAWC gamma-ray catalog and 14 years of IceCube track-like data. No significant neutrino emission from the direction of the HAWC sources was found. We report the best-fit gamma-ray model and 90% CL neutrino flux limit from the 22 sources. From the neutrino flux limit, we conclude that the gamma-ray emission from five of the sources can not be produced purely from hadronic interactions. We report the limit for the fraction of gamma rays produced by hadronic interactions for these five sources.
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- 2024
5. Tracing the evolutionary pathways of dust and cold gas in high-z quiescent galaxies with SIMBA
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Lorenzon, G., Donevski, D., Lisiecki, K., Lovell, C., Romano, M., Narayanan, D., Davé, R., Man, A., Whitaker, K. E., Nanni, A., Long, A., Lee, M. M., Junais, Małek, K., Rodighiero, G., and Li, Q.
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Astrophysics - Astrophysics of Galaxies - Abstract
Recent discoveries of copious amounts of dust in quiescent galaxies (QGs) at high redshifts ($z\gtrsim 1-2$) challenge the conventional view that these objects have poor interstellar medium (ISM) in proportion to their stellar mass. We use the SIMBA cosmological simulation to explore the evolution of dust and cold gas content in QGs in relation to the quenching processes affecting them. We track the changes in the ISM dust abundance across the evolutionary history of QGs identified at $0 \lesssim z \lesssim2$ in the field and cluster environments. The QGs quench via diverse pathways, both rapid and slow, and exhibit a wide range of times elapsed between the quenching event and cold gas removal (from $\sim650$ Myr to $\sim8$ Gyr). We find that quenching modes attributed to the feedback from active galactic nuclei (AGN) do not affect dust and cold gas within the same timescales. Remarkably, QGs may replenish their dust content in the quenched phase primarily due to internal processes and marginally by external factors such as minor mergers. The key mechanism for re-formation of dust is prolonged grain growth on gas-phase metals, it is effective within $\sim100$ Myr after the quenching event, and rapidly increases the dust-to-gas mass ratio in QGs above the standard values ($\delta_{\rm DGR}\gtrsim1/100$). As a result, despite heavily depleted cold gas reservoirs, roughly half of QGs maintain little evolution in their ISM dust with stellar age within the first 2 Gyr following the quenching. Overall, we predict that relatively dusty QGs ($M_{\rm dust}/M_{\star}\gtrsim10^{-3}-10^{-4}$) arise from both fast and slow quenchers, and are prevalent in systems of intermediate and low stellar masses ($9<\log(M_{\star}/M_{\odot})<10.5$). This prediction poses an immediate quest for observational synergy between e.g., James Webb Space Telescope (JWST) and the Atacama Large Millimeter Array (ALMA)., Comment: 21 pages, 10 figures, 1 table, submitted to A&A
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- 2024
6. Uptake and experience of professional interpreting services in primary care in a South Asian population: a national cross-sectional study
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Hieke, G., Williams, E. D., Gill, P., Black, G.B., Islam, L., Vindrola-Padros, C., Yargawa, J., Braun, S., and Whitaker, K. L.
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- 2024
- Full Text
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7. The JWST FRESCO Survey: Legacy NIRCam/Grism Spectroscopy and Imaging in the two GOODS Fields
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Oesch, P. A., Brammer, G., Naidu, R. P., Bouwens, R. J., Chisholm, J., Illingworth, G. D., Matthee, J., Nelson, E., Qin, Y., Reddy, N., Shapley, A., Shivaei, I., van Dokkum, P., Weibel, A., Whitaker, K., Wuyts, S., Covelo-Paz, A., Endsley, R., Fudamoto, Y., Giovinazzo, E., Herard-Demanche, T., Kerutt, J., Kramarenko, I., Labbe, I., Leonova, E., Lin, J., Magee, D., Marchesini, D., Maseda, M., Mason, C., Matharu, J., Meyer, R. A., Neufeld, C., Lyon, G. Prieto, Schaerer, D., Sharma, R., Shuntov, M., Smit, R., Stefanon, M., Wyithe, J. S. B., and Xiao, M.
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Astrophysics - Astrophysics of Galaxies - Abstract
We present the JWST Cycle 1 53.8hr medium program FRESCO, short for "First Reionization Epoch Spectroscopically Complete Observations". FRESCO covers 62 arcmin$^2$ in each of the two GOODS/CANDELS fields for a total area of 124 arcmin$^2$ exploiting JWST's powerful new grism spectroscopic capabilities at near-infrared wavelengths. By obtaining ~2 hr deep NIRCam/grism observations with the F444W filter, FRESCO yields unprecedented spectra at R~1600 covering 3.8 to 5.0 $\mu$m for most galaxies in the NIRCam field-of-view. This setup enables emission line measurements over most of cosmic history, from strong PAH lines at z~0.2-0.5, to Pa$\alpha$ and Pa$\beta$ at z~1-3, HeI and [SIII] at z~2.5-4.5, H$\alpha$ and [NII] at z~5-6.5, up to [OIII] and H$\beta$ for z~7-9 galaxies, and possibly even [OII] at z~10-12. FRESCO's grism observations provide total line fluxes for accurately estimating galaxy stellar masses and calibrating slit-loss corrections of NIRSpec/MSA spectra in the same field. Additionally, FRESCO results in a mosaic of F182M, F210M, and F444W imaging in the same fields to a depth of ~28.2 mag (5 $\sigma$ in 0.32" diameter apertures). Together with this publication, the v1 imaging mosaics are released as high-level science products via MAST. Here, we describe the overall survey design and the key science goals that can be addressed with FRESCO. We also highlight several, early science results, including: spectroscopic redshifts of Lyman break galaxies that were identified almost 20 years ago, the discovery of broad-line active galactic nuclei at z>4, and resolved Pa$\alpha$ maps of galaxies at z~1.4. These results demonstrate the enormous power for serendipitous discovery of NIRCam/grism observations., Comment: 12 pages, 11 figures; MNRAS in press; for more information on the survey and data releases, see http://jwst-fresco.astro.unige.ch/ and https://archive.stsci.edu/hlsp/fresco
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- 2023
8. The ALMA-ALPAKA survey I: high-resolution CO and [CI] kinematics of star-forming galaxies at z = 0.5-3.5
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Rizzo, F., Roman-Oliveira, F., Fraternali, F., Frickmann, D., Valentino, F., Brammer, G., Zanella, A., Kokorev, V., Popping, G., Whitaker, K. E., Kohandel, M., Magdis, G. E., Di Mascolo, L., Ikeda, R., Jin, S., and Toft, S.
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Astrophysics - Astrophysics of Galaxies - Abstract
Spatially-resolved studies of the kinematics of galaxies provide crucial insights into their assembly and evolution, enabling to infer the properties of the dark matter halos, derive the impact of feedback on the ISM, characterize the outflow motions. To date, most of the kinematic studies at z=0.5-3.5 were obtained using emission lines tracing the warm, ionized gas. However, whether these provide an exhaustive or only a partial view of the dynamics of galaxies and of the properties of the ISM is still debated. Complementary insights on the cold gas kinematics are therefore needed. We present ALPAKA, a project aimed at gathering high-resolution observations of CO and [CI] emission lines of star-forming galaxies at z=0.5-3.5 from the ALMA public archive. With 147 hours of total integration time, ALPAKA assembles ~0.25'' observations for 28 star-forming galaxies, the largest sample with spatially-resolved cold gas kinematics as traced by either CO or [CI] at z>0.5. By combining multi-wavelength ancillary data, we derive the stellar masses ($M_{\star}$) and star-formation rates (SFR) for our targets, finding values of $M_{\star}\gtrsim 10^{10}$ M$_{\odot}$ and SFR of 10-3000 M$_{\odot}$/yr. A large fraction of ALPAKA galaxies (19/28) lie in overdense regions (clusters, groups, and protoclusters). We exploit the ALMA data to infer their dynamical state and we find that 19/28 ALPAKA galaxies are rotating disks, 2 are interacting systems, while for the remaining 7 sources the classification is uncertain. The disks have velocity dispersion values that are typically larger in the innermost regions than in the outskirts, with a median value for the entire disk sample of 35$^{+11}_{-9}$ km/s. Despite the bias of our sample towards galaxies hosting very energetic mechanisms, the ALPAKA disks have high ratios of ordered-to-random motion ($V/\sigma$) with a median value of 9$^{+7}_{-2}$., Comment: 36 pages, 23 figures, 5 tables; accepted for publication in A&A. The data and the outputs of the kinematic analysis will be made available at https://alpaka-survey.github.io/index.html
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- 2023
9. The Gas Mass Reservoir of Quiescent Galaxies at Cosmic Noon
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Blánquez-Sesé, David, Gómez-Guijarro, C., Magdis, G. E., Magnelli, B., Gobat, R., Daddi, E., Franco, M., Whitaker, K., Valentino, F., Adscheid, S., Schinnerer, E., Zanella, A., Xiao, M., Wang, T., Liu, D., Kokorev, V., and Elbaz, D.
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Astrophysics - Astrophysics of Galaxies - Abstract
We present a 1.1mm stacking analysis of moderately massive (log($M_{*}$/$M_{\odot}$) = 10.7 $\pm$ 0.2) quiescent galaxies (QGs) at $\langle z\rangle \sim1.5$, searching for cold dust continuum emission, an excellent tracer of dust and gas mass. Using both the recent GOODS-ALMA survey as well as the full suite of ALMA Band-6 ancillary data in the GOODS-S field, we report the tentative detection of dust continuum equivalent of dust mass log($M_{dust}$/$M_{\odot}$) = 7.47 $\pm$ 0.13 and gas mass log($M_{gas}$/$M_{\odot}$) = 9.42 $\pm$ 0.14. The emerging gas fraction is $f_{gas}$ = 5.3 $\pm$ 1.8%, consistent with the results of previous stacking analyses based on lower resolution sub(mm) observations. Our results support the scenario where high-z QGs have an order of magnitude larger $f_{gas}$ compared to their local counterparts and have experienced quenching with a non negligible gas reservoir in their interstellar medium - i.e. with gas retention. Subsequent analysis yields an anti-correlation between the $f_{gas}$ and the stellar mass of QGs, especially in the high mass end where galaxies reside in the most massive haloes. The $f_{gas}$ - $M_{*}$ anti-correlation promotes the selection bias as a possible solution to the tension between the stacking results pointing towards gas retention in high-z QGs of moderate $M_{*}$ and the studies of individual targets that favour a fully depleted ISM in massive (log($M_{*}$/$M_{\odot}$) high-z QGs., Comment: Accepted to A&A on the 16/03/2023
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- 2023
- Full Text
- View/download PDF
10. HAWC Detection of a TeV Halo Candidate Surrounding a Radio-quiet pulsar
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Albert, A., Alfaro, R., Arteaga-Velázquez, J. C., Belmont-Moreno, E., Capistrán, T., Carramiñana, A., Casanova, S., Cotzomi, J., de León, S. Coutiño, De la Fuente, E., Hernandez, R. Diaz, DuVernois, M. A., Díaz-Vélez, J. C., Espinoza, C., Fan, K. L., Fraija, N., Fang, K., García-González, J. A., Garfias, F., Jardin-Blicq, Armelle, González, M. M., Goodman, J. A., Harding, J. P., Hernandez, S., Huang, D., Hueyotl-Zahuantitla, F., Iriarte, A., Joshi, V., Lara, A., Lee, J., Vargas, H. León, Linnemann, J. T., Longinotti, A. L., Luis-Raya, G., Malone, K., Martinez, O., Martínez-Castro, J., Matthews, J. A., Morales-Soto, J. A., Moreno, E., Mostafá, M., Nayerhoda, A., Nellen, L., Newbold, M., Nisa, M. U., Araujo, Y. Pérez, Pérez-Pérez, E. G., Rho, C. D., Rosa-González, D., Schneider, M., Serna-Franco, J., Smith, A. J., Son, Y., Springer, R. W., Tollefson, K., Torres, I., Torres-Escobedo, R., Wang, X., Whitaker, K., Willox, E., Zhou, H., and de León, C.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Extended very-high-energy (VHE; 0.1-100 TeV) $\gamma$-ray emission has been observed around several middle-aged pulsars and referred to as ``TeV halos". Their formation mechanism remains under debate. It is also unknown whether they are ubiquitous or related to certain subgroup of pulsars. With 2321 days of observation, the High Altitude Water Cherenkov (HAWC) Gamma-Ray Observatory detected VHE $\gamma$-ray emission at the location of the radio-quiet pulsar PSR J0359+5414 with $>6\sigma$ significance. By performing likelihood tests with different spectral and spatial models and comparing the TeV spectrum with multi-wavelength observations of nearby sources, we show that this excess is consistent with a TeV halo associated with PSR J0359+5414, though future observation of HAWC and multi-wavelength follow-ups are needed to confirm this nature. This new halo candidate is located in a non-crowded region in the outer Galaxy. It shares similar properties to the other halos but its pulsar is younger and radio-quiet. Our observation implies that TeV halos could commonly exist around pulsars and their formation does not depend on the configuration of the pulsar magnetosphere.
- Published
- 2023
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11. Search for Gamma-Ray and Neutrino Coincidences Using HAWC and ANTARES Data
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Solares, H. A. Ayala, Coutu, S., Cowen, D., Fox, D. B., Grégoire, T., McBride, F., Mostafá, M., Murase, K., Wissel, S., Albert, A., Alves, S., André, M., Ardid, M., Ardid, S., Aubert, J. -J., Aublin, J., Baret, B., Basa, S., Belhorma, B., Bendahman, M., Benfenati, F., Bertin, V., Biagi, S., Bissinger, M., Boumaaza, J., Bouta, M., Bouwhuis, M. C., Brânzaş, H., Bruijn, R., Brunner, J., Busto, J., Caiffi, B., Calvo, D., Capone, A., Caramete, L., Carr, J., Carretero, V., Celli, S., Chabab, M., Chau, T. N., Moursli, R. Cherkaoui El, Chiarusi, T., Circella, M., Coelho, J. A. B., Coleiro, A., Coniglione, R., Coyle, P., Creusot, A., Díaz, A. F., de Wasseige, G., De Martino, B., Distefano, C., Di Palma, I., Domi, A., Donzaud, C., Dornic, D., Drouhin, D., Eberl, T., van Eeden, T., van Eijk, D., Khayati, N. El, Enzenhöfer, A., Fermani, P., Ferrara, G., Filippini, F., Fusco, L., García, J., Gay, P., Glotin, H., Gozzini, R., Ruiz, R. Gracia, Graf, K., Guidi, C., Hallmann, S., van Haren, H., Heijboer, A. J., Hello, Y., Hernández-Rey, J. J., Hößl, J., Hofestädt, J., Huang, F., Illuminati, G., James, C. W., Jisse-Jung, B., de Jong, M., de Jong, P., Kadler, M., Kalekin, O., Katz, U., Kouchner, A., Kreykenbohm, I., Kulikovskiy, V., Lahmann, R., Lamoureux, M., Breton, R. Le, Lefèvre, D., Leonora, E., Levi, G., Stum, S. Le, Lopez-Coto, D., Loucatos, S., Maderer, L., Manczak, J., Marcelin, M., Margiotta, A., Marinelli, A., Martínez-Mora, J. A., Melis, K., Migliozzi, P., Moussa, A., Muller, R., Nauta, L., Navas, S., Nezri, E., Fearraigh, B. Ó, Păaun, A., Păvălaş, G. E., Pellegrino, C., Perrin-Terrin, M., Pestel, V., Piattelli, P., Pieterse, C., Poirè, C., Popa, V., Pradier, T., Randazzo, N., Real, D., Reck, S., Riccobene, G., Romanov, A., Sánchez-Losa, A., Samtleben, D. F. E., Sanguineti, M., Sapienza, P., Schnabel, J., Schumann, J., Schüssler, F., Seneca, J., Spurio, M., Stolarczyk, Th., Taiuti, M., Tayalati, Y., Tingay, S. J., Vallage, B., Van Elewyck, V., Versari, F., Viola, S., Vivolo, D., Wilms, J., Zavatarelli, S., Zegarelli, A., Zornoza, J. D., Zúñiga, J., Alvarez, C., Arteaga-Velázquez, J. C., Babu, R., Belmont-Moreno, E., Caballero-Mora, K. S., Capistrán, T., Carramiñana, A., Casanova, S., Cotti, U., Chaparro-Amaro, O., Cotzomi, J., de León, S. Coutiño, De la Fuente, E., de León, C., Hernandez, R. Diaz, DuVernois, M. A., Durocher, M., Díaz-Vélez, J. C., Engel, K., Espinoza, C., Fan, K. L., Alonso, M. Fernández, Fraija, N., García-González, J. A., Garfias, F., González, M. M., Goodman, J. A., Harding, J. P., Hernandez, S., Huang, D., Hueyotl-Zahuantitla, F., Hüntemeyer, P., Iriarte, A., Joshi, V., Kaufmann, S., Lara, A., Vargas, H. León, Linnemann, J. T., Longinotti, A. L., Luis-Raya, G., Malone, K., Martinez, O., Martinez-Castellanos, I., Martínez-Castro, J., Matthews, J. A., Miranda-Romagnoli, P., Morales-Soto, J. A., Moreno, E., Nayerhoda, A., Nellen, L., Nisa, M. U., Noriega-Papaqui, R., Omodei, N., Peisker, A., Araujo, Y. Pérez, Pérez-Pérez, E. G., Rho, C. D., Rosa-González, D., Ruiz-Velasco, E., Salazar, H., Greus, F. Salesa, Sandoval, A., Schneider, M., Smith, A. J., Son, Y., Springer, R. W., Tibolla, O., Tollefson, K., Torres, I., Torres-Escobedo, R., Turner, R., Ureña-Mena, F., Varela, E., Wang, X., Whitaker, K., Willox, E., Zepeda, A., and Zhou, H.
- Subjects
Astrophysics - High Energy Astrophysical Phenomena - Abstract
In the quest for high-energy neutrino sources, the Astrophysical Multimessenger Observatory Network (AMON) has implemented a new search by combining data from the High Altitude Water Cherenkov (HAWC) observatory and the Astronomy with a Neutrino Telescope and Abyss environmental RESearch (ANTARES) neutrino telescope. Using the same analysis strategy as in a previous detector combination of HAWC and IceCube data, we perform a search for coincidences in HAWC and ANTARES events that are below the threshold for sending public alerts in each individual detector. Data were collected between July 2015 and February 2020 with a livetime of 4.39 years. Over this time period, 3 coincident events with an estimated false-alarm rate of $< 1$ coincidence per year were found. This number is consistent with background expectations., Comment: 12 pages, 5 figures, 3 tables
- Published
- 2022
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12. University Stakeholders Largely Unaware and Unsupportive of University Pouring Rights Contracts with Companies Supplying Sugar-Sweetened Beverages
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Thompson, H. G., Whitaker, K. M., Young, R., and Carr, L. J.
- Abstract
Background: Pouring rights contracts are agreements in which beverage companies pay universities for exclusive marketing and rights to sell sugar-sweetened beverages (SSB) in campus. This study explored university stakeholder's awareness and opinions of university pouring rights contracts. Methods: Nine hundred fifteen university stakeholders self-reported their awareness and support of pouring rights contracts along with several possible determinants of support (age, gender, nutrition education, beliefs about SSBs, beverage intake). Results: About 64.2% of participants reported no awareness of pouring rights contracts whereas only 38% reported agreeing with university pouring rights contracts. Males, undergraduate students, and those who felt individuals are responsible for their SSB consumption were more likely to support pouring rights contracts. Conclusions: University stakeholders were largely unaware of and unsupportive of pouring rights contracts. Universities are encouraged to consider the health impacts and opinions of university stakeholders when deciding whether to enter into pouring rights contracts.
- Published
- 2023
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13. The Interstellar Medium of Quiescent Galaxies and its Evolution With Time
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Magdis, Georgios E., Gobat, R., Valentino, F., Daddi, E., Zanella, A., Kokorev, V., Toft, S., Jin, S., and Whitaker, K.
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Astrophysics - Astrophysics of Galaxies - Abstract
We characterise the basic far-IR (FIR) properties and the gas mass fraction of massive (
~ 11.0) quiescent galaxies (QGs) and explore how these evolve from z = 2.0 to the present day. We use robust, multi-wavelength (mid- to far-IR and sub-millimetre to radio) stacking ensembles of homogeneously selected and mass complete samples of log(M*/Msun) > 10.8 QGs. We find that the dust to stellar mass ratio (Md/M*) rises steeply as a function of redshift up to z~1.0 and then remains flat at least out to z = 2.0. Using Md as a proxy of gas mass (Mgas), we find a similar trend for the evolution of the gas mass fraction (fgas) with z > 1.0 QGs having fgas ~ 7.0% (for solar metallicity). This fgas is 3 - 10 times lower than that of normal star forming galaxies (SFGs) at their corresponding redshift but ~3 and ~10 times larger compared to that of z = 0.5 and local QGs. Furthermore, the inferred gas depletion time scales are comparable to that of local SFGs and systematically longer than that of main sequence galaxies at their corresponding redshifts. Our analysis also reveals that the average dust temperature (Td) of massive QGs remains roughly constant (< Td > = 21.0 \pm 2.0K) at least out to z ~ 2.0 and is substantially colder (~ 10K) compared to that of z > 0 SFGs. This motivated us to construct and release a redshift-invariant template IR SED, that we use to make predictions for ALMA observations and to explore systematic effects in the Mgas estimates of massive, high-z QGs. Finally, we discuss how a simple model that considers progenitor-bias can effectively reproduce the observed evolution of Md/M* and fgas. Our results indicate universal initial interstellar medium conditions for quenched galaxies and a large degree of uniformity in their internal processes across cosmic time., Comment: Accepted for publication in A&A - Published
- 2021
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14. An ALMA survey of the SCUBA-2 Cosmology Legacy Survey UKIDSS/UDS field: Dust attenuation in high-redshift Lyman break Galaxies
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Koprowski, M. P., Coppin, K. E. K., Geach, J. E., Dudzeviciute, U., Smail, Ian, Almaini, O., An, Fangxia, Blain, A. W., Chapman, S. C., Chen, Chian-Chou, Conselice, C. J., Dunlop, J. S., Farrah, D., Gullberg, B., Hartley, W., Ivison, R. J., Karska, A., Maltby, D., Michałowski, M. J., Pope, A., Salim, S., Scott, D., Simpson, C. J., Simpson, J. M., Swinbank, A. M., Thomson, A. P., Wardlow, J. L., van der Werf, P. P., and Whitaker, K. E.
- Subjects
Astrophysics - Astrophysics of Galaxies - Abstract
We analyse 870um Atacama Large Millimetre Array (ALMA) dust continuum detections of 41 canonically-selected z~3 Lyman-break galaxies (LBGs), as well as 209 ALMA-undetected LBGs, in follow-up of SCUBA-2 mapping of the UKIDSS Ultra Deep Survey (UDS) field. We find that our ALMA-bright LBGs lie significantly off the locally calibrated IRX-beta relation and tend to have relatively bluer rest-frame UV slopes (as parametrised by beta), given their high values of the 'infrared excess' (IRX=L_IR/L_UV), relative to the average 'local' IRX-beta relation. We attribute this finding in part to the young ages of the underlying stellar populations but we find that the main reason behind the unusually blue UV slopes are the relatively shallow slopes of the corresponding dust attenuation curves. We show that, when stellar masses are being established via SED fitting, it is absolutely crucial to allow the attenuation curves to vary (rather than fixing it on Calzetti-like law), where we find that the inappropriate curves may underestimate the resulting stellar masses by a factor of ~2-3x on average. In addition, we find these LBGs to have relatively high specific star-formation rates (sSFRs), dominated by the dust component, as quantified via the fraction of obscured star formation ( f_obs = SFR_IR/SFR_(UV+IR)). We conclude that the ALMA-bright LBGs are, by selection, massive galaxies undergoing a burst of a star formation (large sSFRs, driven, for example, by secular or merger processes), with a likely geometrical disconnection of the dust and stars, responsible for producing shallow dust attenuation curves., Comment: 17 pages, 12 figures. Resubmitted to MNRAS after referee report
- Published
- 2020
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15. An X-ray Detection of Star Formation In a Highly Magnified Giant Arc
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Bayliss, M. B., McDonald, M., Sharon, K., Gladders, M. D., Florian, M., Chisholm, J., Dahle, H., Mahler, G., Paterno-Mahler, R., Rigby, J. R., Rivera-Thorsen, E., Whitaker, K. E., Allen, S., Benson, B. A., Bleem, L. E., Brodwin, M., Canning, R. E. A., Chiu, I., Hlavacek-Larrondo, J., Khullar, G., Reichardt, C., and Vieira, J. D.
- Subjects
Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies - Abstract
In the past decade, our understanding of how stars and galaxies formed during the first 5 billion years after the Big Bang has been revolutionized by observations that leverage gravitational lensing by intervening masses, which act as natural cosmic telescopes to magnify background sources. Previous studies have harnessed this effect to probe the distant universe at ultraviolet, optical, infrared and millimeter wavelengths. However, strong lensing studies of young, star-forming galaxies have never extended into X-ray wavelengths, which uniquely trace high-energy phenomena. Here we report an X-ray detection of star formation in a highly magnified, strongly lensed galaxy. This lensed galaxy, seen during the first third of the history of the Universe, is a low--mass, low--metallicity starburst with elevated X-ray emission, and is a likely analog to the first generation of galaxies. Our measurements yield insight into the role that X-ray emission from stellar populations in the first generation of galaxies may play in re-ionizing the Universe. This observation paves the way for future strong lensing-assisted X-ray studies of distant galaxies reaching orders of magnitude below the detection limits of current deep fields, and previews the depths that will be attainable with future X-ray observatories., Comment: Published in Nature Astronomy
- Published
- 2019
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16. Star Formation at z=2.481 in the Lensed Galaxy SDSS J1110+6459, II: What is missed at the normal resolution of the Hubble Space Telescope?
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Rigby, J. R., Johnson, T. L., Sharon, K., Whitaker, K., Gladders, M. D., Florian, M., Lotz, J., Bayliss, M., and Wuyts, E.
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Astrophysics - Astrophysics of Galaxies - Abstract
For lensed galaxy SGAS J111020.0+645950.8 at redshift z=2.481, which is magnified by a factor of 28 +- 8, we analyze the morphology of star formation as traced by rest-frame ultraviolet emission, in both the highly-magnified source plane, and in simulations of how this galaxy would appear without lensing magnification. Were this galaxy not lensed but drawn from an HST deep field, we would conclude that almost all its star formation arises from an exponential disk (S\'ersic index of 1.0 +- 0.4) with an effective radius of r_e = 2.7 +- 0.3 kpc measured from two-dimensional fitting to F606W using Galfit, and r_e=1.9 +- 0.1 kpc measured by fitting a radial profile to F606W elliptical isophotes. At the normal spatial resolution of the deep fields, there is no sign of clumpy star formation within SGAS J111020.0+645950.8 . However, the enhanced spatial resolution enabled by gravitational lensing tells a very different story: much of the star formation arises in two dozen clumps with sizes of r=30--50 pc spread across the 7 kpc length of the galaxy. The color and spatial distribution of the diffuse component suggests that still smaller clumps are unresolved. Despite this clumpy, messy morphology, the radial profile is still well-characterized by an exponential profile. In this lensed galaxy, stars are forming in complexes with sizes well below 100 pc; such sizes are wholly unexplored by surveys of galaxy evolution at 1
- Published
- 2017
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17. Galaxy environment in the 3D-HST fields. Witnessing the onset of satellite quenching at z ~ 1-2
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Fossati, M., Wilman, D. J., Mendel, J. T., Saglia, R. P., Galametz, A., Beifiori, A., Bender, R., Chan, J. C. C., Fabricius, M., Bandara, K., Brammer, G. B., Davies, R., Schreiber, N. M. Förster, Genzel, R., Hartley, W., Kulkarni, S. K., Lang, P., Momcheva, I. G., Nelson, E. J., Skelton, R., Tacconi, L. J., Tadaki, K., Übler, H., van Dokkum, P. G., Wisnioski, E., Whitaker, K. E., Wuyts, E., and Wuyts, S.
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Astrophysics - Astrophysics of Galaxies - Abstract
We make publicly available a catalog of calibrated environmental measures for galaxies in the five 3D-HST/CANDELS deep fields. Leveraging the spectroscopic and grism redshifts from the 3D-HST survey, multi wavelength photometry from CANDELS, and wider field public data for edge corrections, we derive densities in fixed apertures to characterize the environment of galaxies brighter than $JH_{140} < 24$ mag in the redshift range $0.5
- Published
- 2016
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18. Letermovir Use Following Lung Transplantation: A Single Center Review
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Mezochow, A.K., primary, He, K.D., additional, Whitaker, K., additional, Blumberg, E., additional, Crespo, M., additional, and Courtwright, A., additional
- Published
- 2024
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19. Geometry of Star-Forming Galaxies from SDSS, 3D-HST and CANDELS
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van der Wel, A., Chang, Yu-Yen, Bell, E. F., Holden, B. P., Ferguson, H. C., Giavalisco, M., Rix, H. -W., Skelton, R., Whitaker, K., Momcheva, I., Brammer, G., Kassin, S. A., Martig, M., Dekel, A., Ceverino, D., Koo, D. C., Mozena, M., van Dokkum, P. G., Franx, M., Faber, S. M., and Primack, J.
- Subjects
Astrophysics - Astrophysics of Galaxies - Abstract
We determine the intrinsic, 3-dimensional shape distribution of star-forming galaxies at 0
1e10 Msol) disks are the most common geometric shape at all z < 2. Lower-mass galaxies at z>1 possess a broad range of geometric shapes: the fraction of elongated (prolate) galaxies increases toward higher redshifts and lower masses. Galaxies with stellar mass 1e9 Msol (1e10 Msol) are a mix of roughly equal numbers of elongated and disk galaxies at z~1 (z~2). This suggests that galaxies in this mass range do not yet have disks that are sustained over many orbital periods, implying that galaxies with present-day stellar mass comparable to that of the Milky Way typically first formed such sustained stellar disks at redshift z~1.5-2. Combined with constraints on the evolution of the star formation rate density and the distribution of star formation over galaxies with different masses, our findings imply that, averaged over cosmic time, the majority of stars formed in disks., Comment: Published in ApJ Letters - Published
- 2014
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20. 3D-HST+CANDELS: The Evolution of the Galaxy Size-Mass Distribution since $z=3$
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van der Wel, A., Franx, M., van Dokkum, P. G., Skelton, R. E., Momcheva, I. G., Whitaker, K. E., Brammer, G. B., Bell, E. F., Rix, H. -W., Wuyts, S., Ferguson, H. C., Holden, B. P., Barro, G., Koekemoer, A. M., Chang, Yu-Yen, McGrath, E. J., Haussler, B., Dekel, A., Behroozi, P., Fumagalli, M., Leja, J., Lundgren, B. F., Maseda, M. V., Nelson, E. J., Wake, D. A., Patel, S. G., Labbe, I., Faber, S. M., Grogin, N. A., and Kocevski, D. D.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
Spectroscopic + photometric redshifts, stellar mass estimates, and rest-frame colors from the 3D-HST survey are combined with structural parameter measurements from CANDELS imaging to determine the galaxy size-mass distribution over the redshift range 0
3x10^9 M_sol, and steep, R_eff M_star^0.75, for early-type galaxies with stellar mass >2x10^10 M_sol. The intrinsic scatter is <~0.2 dex for all galaxy types and redshifts. For late-type galaxies, the logarithmic size distribution is not symmetric, but skewed toward small sizes: at all redshifts and masses a tail of small late-type galaxies exists that overlaps in size with the early-type galaxy population. The number density of massive (~10^11 M_sol), compact (R_eff < 2 kpc) early-type galaxies increases from z=3 to z=1.5-2 and then strongly decreases at later cosmic times., Comment: Published in ApJ. Structural parameter measurements publicly available at http://www.mpia-hd.mpg.de/homes/vdwel/3dhstcandels.html - Published
- 2014
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21. The Age Spread of Quiescent Galaxies with the NEWFIRM Medium-band Survey: Identification of the Oldest Galaxies out to z~2
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Whitaker, K. E., van Dokkum, P. G., Brammer, G., Kriek, M., Franx, M., Labbe, I., Marchesini, D., Quadri, R. F., Bezanson, R., Illingworth, G. D., Lee, K. -S., Muzzin, A., Rudnick, G., and Wake, D. A.
- Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
With a complete, mass-selected sample of quiescent galaxies from the NEWFIRM Medium-Band Survey (NMBS), we study the stellar populations of the oldest and most massive galaxies (>10^11 Msun) to high redshift. The sample includes 570 quiescent galaxies selected based on their extinction-corrected U-V colors out to z=2.2, with accurate photometric redshifts, sigma_z/(1+z)~2%, and rest-frame colors, sigma_U-V~0.06 mag. We measure an increase in the intrinsic scatter of the rest-frame U-V colors of quiescent galaxies with redshift. This scatter in color arises from the spread in ages of the quiescent galaxies, where we see both relatively quiescent red, old galaxies and quiescent blue, younger galaxies towards higher redshift. The trends between color and age are consistent with the observed composite rest-frame spectral energy distributions (SEDs) of these galaxies. The composite SEDs of the reddest and bluest quiescent galaxies are fundamentally different, with remarkably well-defined 4000A- and Balmer-breaks, respectively. Some of the quiescent galaxies may be up to 4 times older than the average age- and up to the age of the universe, if the assumption of solar metallicity is correct. By matching the scatter predicted by models that include growth of the red sequence by the transformation of blue galaxies to the observed intrinsic scatter, the data indicate that most early-type galaxies formed their stars at high redshift with a burst of star formation prior to migrating to the red sequence. The observed U-V color evolution with redshift is weaker than passive evolution predicts; possible mechanisms to slow the color evolution include increasing amounts of dust in quiescent galaxies towards higher redshift, red mergers at z<1, and a frosting of relatively young stars from star formation at later times., Comment: 20 pages, 20 figures, accepted for publication in ApJ
- Published
- 2010
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22. The Dead Sequence: A Clear Bimodality in Galaxy Colors from z=0 to z=2.5
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Brammer, G. B., Whitaker, K. E., van Dokkum, P. G., Marchesini, D., Labbe, I., Franx, M., Kriek, M., Quadri, R. F., Illingworth, G., Lee, K. -S., Muzzin, A., and Rudnick, G.
- Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We select 25,000 galaxies from the NEWFIRM Medium Band Survey (NMBS) to study the rest-frame U-V color distribution of galaxies at 0 < z < 2.5. The five unique NIR filters of the NMBS enable the precise measurement of photometric redshifts and rest-frame colors for 9,900 galaxies at 1 < z < 2.5. The rest-frame U-V color distribution at all z<~2.5 is bimodal, with a red peak, a blue peak, and a population of galaxies in between (the green valley). Model fits to the optical-NIR SEDs and the distribution of MIPS-detected galaxies indicate that the colors of galaxies in the green valley are determined largely by the amount of reddening by dust. This result does not support the simplest interpretation of green valley objects as a transition from blue star-forming to red quiescent galaxies. We show that correcting the rest-frame colors for dust reddening allows a remarkably clean separation between the red and blue sequences up to z~2.5. Our study confirms that dusty starburst galaxies can contribute a significant fraction to red sequence samples selected on the basis of a single rest-frame color (i.e. U-V), so extra care must be taken if samples of truly "red and dead" galaxies are desired. Interestingly, of galaxies detected at 24 microns, 14% remain on the red sequence after applying the reddening correction., Comment: 5 pages + 4 figures, emulateapj format. Accepted for publication in ApJ Letters
- Published
- 2009
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23. Cancer risk‐factor and symptom awareness among adults with intellectual disabilities, paid and unpaid carers, and healthcare practitioners: a scoping review
- Author
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Gil, N., primary, Cox, A., additional, Whitaker, K. L., additional, and Kerrison, R. S., additional
- Published
- 2023
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24. The ALMA-ALPAKA survey
- Author
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Rizzo, F., primary, Roman-Oliveira, F., additional, Fraternali, F., additional, Frickmann, D., additional, Valentino, F. M., additional, Brammer, G., additional, Zanella, A., additional, Kokorev, V., additional, Popping, G., additional, Whitaker, K. E., additional, Kohandel, M., additional, Magdis, G. E., additional, Di Mascolo, L., additional, Ikeda, R., additional, Jin, S., additional, and Toft, S., additional
- Published
- 2023
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25. Hubble Space Telescope Images of Red Mergers: How Dry are They?
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Whitaker, K. E. and van Dokkum, P. G.
- Subjects
Astrophysics - Abstract
Mergers between red galaxies are observed to be common in the nearby Universe, and are thought to be the dominant mechanism by which massive galaxies grow their mass at late times. These ``dry'' mergers can be readily identified in very deep ground based images, thanks to their extended low surface brightness tidal features. However, ground-based images lack the required resolution to determine the morphologies of the merging galaxies, and to measure the amount of dust and associated gas. We present HST/ACS and WFPC2 observations of a sample of 31 bulge-dominated red-sequence galaxies at z~0.1, comprised of ongoing mergers, merger remnants, and undisturbed galaxies. Nearly all galaxies have early-type morphologies and most are well-fit by r^1/4 law surface brightness profiles. We find that only 10% of the galaxies show evidence for the presence of dust. The amount of cold gas (or its upper limit) is calculated from the mean color-excess, assuming a simple relation between gas mass and dust mass. The gas mass is low for all galaxies, and we find that Mgas/Mstellar < 3x10^-4. We infer that red mergers in the nearby Universe mostly involve early-type galaxies containing little cold gas and dust. This may imply that the progenitors were mostly devoid of gas and/or that feedback mechanisms are very effective in preventing the gas to cool. The lack of gas in these objects may also imply a relatively large fraction of binary black holes in the centers of massive ellipticals., Comment: 4 pages, 3 figures; to be published in ApJL
- Published
- 2008
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26. Intrusive cognitions, anxiety and cancer
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Whitaker, K. L.
- Subjects
616.994 - Abstract
Since the recognition (DSM-IV; American Psychiatric Association, 1994) of life-threatening illnesses as a stressor that can precipitate posttraumatic stress disorder (PTSD), research has focussed on the issue of PTSD following cancer. Although the utility of a trauma framework has been questioned, understanding symptoms associated with PTSD such as intrusive cognitions may be critical in understanding psychological distress in cancer patients. Research has found that cancer patients experience negative intrusive thoughts, which are associated with marked distress. However, studies have rarely explored the content or nature of intrusions. In addition to verbal intrusions, intrusive memories of illness have been reported in cancer patients. More recently, intrusive imagery has been found in populations of anxious patients and reported to have a causal role in the maintenance of anxiety. Based on the recognition of cancer as a protracted experience involving multiple stressors, future-oriented visual intrusions, as well as intrusive memories and thoughts may play a role in psychological functioning. Chapter 1 is an overview of the literature assessing the presence of posttraumatic stress and posttraumatic stress symptoms in cancer patients. Chapter 2 is a cross-sectional study which showed that anxious prostate cancer patients (N=65) were significantly more likely to report intrusive cognitions compared to matched non-anxious (N=65) prostate cancer patients. Intrusive cognitions were frequent, uncontrollable and associated with significant distress and maladaptive adjustment. Chapter 3 is a cross-sectional study (N=139), which showed that factors such as how patients appraise intrusive cognitions affects anxiety severity and intrusion-related distress, after controlling for intrusion frequency. Chapter 4 provides a discussion of the use of imagery in psychological therapy and how imagery has been used with cancer patients in therapy. Chapter 5 presents two single-case studies of cancer patients completing a short therapy for anxiety, imagery rescripting, aimed at reducing negative properties of intrusive cognitions whilst also alleviating anxiety and depression. The final chapter provides a general discussion of the thesis and presents ideas for future research.
- Published
- 2008
27. The JWST FRESCO survey: legacy NIRCam/grism spectroscopy and imaging in the two GOODS fields
- Author
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Oesch, P A, primary, Brammer, G, additional, Naidu, R P, additional, Bouwens, R J, additional, Chisholm, J, additional, Illingworth, G D, additional, Matthee, J, additional, Nelson, E, additional, Qin, Y, additional, Reddy, N, additional, Shapley, A, additional, Shivaei, I, additional, van Dokkum, P, additional, Weibel, A, additional, Whitaker, K, additional, Wuyts, S, additional, Covelo-Paz, A, additional, Endsley, R, additional, Fudamoto, Y, additional, Giovinazzo, E, additional, Herard-Demanche, T, additional, Kerutt, J, additional, Kramarenko, I, additional, Labbe, I, additional, Leonova, E, additional, Lin, J, additional, Magee, D, additional, Marchesini, D, additional, Maseda, M, additional, Mason, C, additional, Matharu, J, additional, Meyer, R A, additional, Neufeld, C, additional, Prieto Lyon, G, additional, Schaerer, D, additional, Sharma, R, additional, Shuntov, M, additional, Smit, R, additional, Stefanon, M, additional, Wyithe, J S B, additional, and Xiao, M, additional
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- 2023
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28. Cancer risk‐factor and symptom awareness among adults with intellectual disabilities, paid and unpaid carers, and healthcare practitioners: a scoping review.
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Gil, N., Cox, A., Whitaker, K. L., and Kerrison, R. S.
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TUMOR risk factors ,CAREGIVER attitudes ,ATTITUDES of medical personnel ,SYSTEMATIC reviews ,RISK assessment ,HEALTH literacy ,PATIENTS' attitudes ,LEARNING disabilities ,LITERATURE reviews ,INTELLECTUAL disabilities ,HEALTH promotion ,EARLY diagnosis ,DISEASE complications ,ADULTS - Abstract
Background: The physical health of people with intellectual disabilities (ID) has been identified as an area of ongoing concern and priority. Research has increasingly focused on cancer, with studies indicating that people with ID are at an increased risk of cancer and of mortality, compared with the general population. This review aims to systematically identify and synthesise the published academic literature exploring cancer risk‐factor and symptom awareness among people with IDs, carers and healthcare professionals. Methods: In line with Arksey and O'Malley's (2005) framework for scoping reviews, five incremental stages were followed: (1) identifying research question, (2) identifying relevant studies, (3) study selection, (4) extracting and charting of data, and (5) collating, summarising and reporting results. Findings were reported according to the Preferred Reporting Items for Systematic Reviews and Meta‐analyses extension for scoping reviews (PRISMA‐Scr). Results: The search strategy identified 352 records, 16 records met all eligibility criteria and were included for review. The studies address a range of areas including knowledge and awareness of cancer risk‐factors and symptoms and interventions to promote awareness of cancer. Conclusions: Cancer risk‐factor and symptom awareness is low among adults with ID, paid and unpaid carers and healthcare practitioners (HCPs). Theoretically underpinned, co‐designed tools and interventions to improve awareness are lacking. There is uncertainty surrounding how to best support people with ID in raising cancer awareness, even within the professional healthcare environment. There is a predominance of research on breast cancer awareness. Future studies focusing on other cancers are needed to build a complete picture of awareness among adults with IDs, paid and unpaid carers, and HCPs. [ABSTRACT FROM AUTHOR]
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- 2024
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29. Assessing long-term neuroinflammatory responses to encephalopathy using MRI approaches in a rat endotoxemia model
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Towner, Rheal A., Saunders, D., Smith, N., Towler, W., Cruz, M., Do, S., Maher, J. E., Whitaker, K., Lerner, M., and Morton, K. A.
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- 2018
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30. Characterization of the tumor microenvironment in classic Hodgkin lymphoma: determining the deep immunophenotypic signature of T cells using mass cytometry
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Niu, A., primary, Whitaker, K., additional, Soekojo, C. Y., additional, Yang, Z. Z., additional, Kim, H. J., additional, Novak, A. J., additional, Ansell, S. M., additional, and Villasboas, J. C., additional
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- 2023
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31. Curiosi and virtuosi : gentlemanly culture, experimental philosophy and political life in England, 1620-1685
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Whitaker, K. S.
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900 ,History - Published
- 1997
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32. The JWST FRESCO survey:legacy NIRCam/grism spectroscopy and imaging in the two GOODS fields
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Oesch, P A, Brammer, G, Naidu, R P, Bouwens, R J, Chisholm, J, Illingworth, G D, Matthee, J, Nelson, E, Qin, Y, Reddy, N, Shapley, A, Shivaei, I, Van dokkum, P, Weibel, A, Whitaker, K, Wuyts, S, Covelo-paz, A, Endsley, R, Fudamoto, Y, Giovinazzo, E, Herard-demanche, T, Kerutt, J, Kramarenko, I, Labbe, I, Leonova, E, Lin, J, Magee, D, Marchesini, D, Maseda, M, Mason, C, Matharu, J, Meyer, R A, Neufeld, C, Prieto lyon, G, Schaerer, D, Sharma, R, Shuntov, M, Smit, R, Stefanon, M, Wyithe, J S B, Xiao, M, Oesch, P A, Brammer, G, Naidu, R P, Bouwens, R J, Chisholm, J, Illingworth, G D, Matthee, J, Nelson, E, Qin, Y, Reddy, N, Shapley, A, Shivaei, I, Van dokkum, P, Weibel, A, Whitaker, K, Wuyts, S, Covelo-paz, A, Endsley, R, Fudamoto, Y, Giovinazzo, E, Herard-demanche, T, Kerutt, J, Kramarenko, I, Labbe, I, Leonova, E, Lin, J, Magee, D, Marchesini, D, Maseda, M, Mason, C, Matharu, J, Meyer, R A, Neufeld, C, Prieto lyon, G, Schaerer, D, Sharma, R, Shuntov, M, Smit, R, Stefanon, M, Wyithe, J S B, and Xiao, M
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- 2023
33. The gas mass reservoir of quiescent galaxies at cosmic noon
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Blánquez-sesé, D., Gómez-guijarro, C., Magdis, G. E., Magnelli, B., Gobat, R., Daddi, E., Franco, M., Whitaker, K., Valentino, F., Adscheid, S., Schinnerer, E., Zanella, A., Xiao, M., Wang, T., Liu, D., Kokorev, V., Elbaz, D., Blánquez-sesé, D., Gómez-guijarro, C., Magdis, G. E., Magnelli, B., Gobat, R., Daddi, E., Franco, M., Whitaker, K., Valentino, F., Adscheid, S., Schinnerer, E., Zanella, A., Xiao, M., Wang, T., Liu, D., Kokorev, V., and Elbaz, D.
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- 2023
34. The ALMA-ALPAKA survey:I. High-resolution CO and [CI] kinematics of star-forming galaxies at z = 0.5–3.5
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Rizzo, F., Roman-oliveira, F., Fraternali, F., Frickmann, D., Valentino, F. M., Brammer, G., Zanella, A., Kokorev, V., Popping, G., Whitaker, K. E., Kohandel, M., Magdis, G. E., Di Mascolo, L., Ikeda, R., Jin, S., Toft, S., Rizzo, F., Roman-oliveira, F., Fraternali, F., Frickmann, D., Valentino, F. M., Brammer, G., Zanella, A., Kokorev, V., Popping, G., Whitaker, K. E., Kohandel, M., Magdis, G. E., Di Mascolo, L., Ikeda, R., Jin, S., and Toft, S.
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- 2023
35. The gas mass reservoir of quiescent galaxies at cosmic noon
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Blánquez, D., primary, Gómez-Guijarro, C., additional, Magdis, G. E., additional, Magnelli, B., additional, Gobat, R., additional, Daddi, E., additional, Franco, M., additional, Whitaker, K., additional, Valentino, F., additional, Adscheid, S., additional, Schinnerer, E., additional, Zanella, A., additional, Xiao, M., additional, Wang, T., additional, Liu, D., additional, Kokorev, V., additional, and Elbaz, D., additional
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- 2023
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36. HAWC Detection of a TeV Halo Candidate Surrounding a Radio-quiet Pulsar
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Albert, A., primary, Alfaro, R., additional, Arteaga-Velázquez, J. C., additional, Ayala Solares, H. A., additional, Belmont-Moreno, E., additional, Capistrán, T., additional, Carramiñana, A., additional, Casanova, S., additional, Cotzomi, J., additional, De León, S. Coutiño, additional, Fuente, E. De la, additional, de León, C., additional, Diaz Hernandez, R., additional, DuVernois, M. A., additional, Díaz-Vélez, J. C., additional, Espinoza, C., additional, Fan, K. L., additional, Fraija, N., additional, Fang, K., additional, García-González, J. A., additional, Garfias, F., additional, Jardin-Blicq, A., additional, González, M. M., additional, Goodman, J. A., additional, Harding, J. P., additional, Hernandez, S., additional, Huang, D., additional, Hueyotl-Zahuantitla, F., additional, Hüntemeyer, P., additional, Iriarte, A., additional, Joshi, V., additional, Lara, A., additional, Lee, J., additional, Vargas, H. León, additional, Linnemann, J. T., additional, Longinotti, A. L., additional, Luis-Raya, G., additional, Malone, K., additional, Martinez, O., additional, Martínez-Castro, J., additional, Matthews, J. A., additional, Morales-Soto, J. A., additional, Moreno, E., additional, Mostafá, M., additional, Nayerhoda, A., additional, Nellen, L., additional, Newbold, M., additional, Nisa, M. U., additional, Araujo, Y. Pérez, additional, Son, Y., additional, Pérez-Pérez, E. G., additional, Rho, C. D., additional, Rosa-González, D., additional, Sandoval, A., additional, Schneider, M., additional, Serna-Franco, J., additional, Smith, A. J., additional, Springer, R. W., additional, Tollefson, K., additional, Torres, I., additional, Torres-Escobedo, R., additional, Wang, X., additional, Whitaker, K., additional, Willox, E., additional, and Zhou, H., additional
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- 2023
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37. Search for Gamma-Ray and Neutrino Coincidences Using HAWC and ANTARES Data
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Solares, H. A. Ayala, primary, Coutu, S., additional, Cowen, D., additional, Fox, D. B., additional, Grégoire, T., additional, McBride, F., additional, Mostafá, M., additional, Murase, K., additional, Wissel, S., additional, Albert, A., additional, Alves, S., additional, André, M., additional, Ardid, M., additional, Ardid, S., additional, Aubert, J.-J., additional, Aublin, J., additional, Baret, B., additional, Basa, S., additional, Belhorma, B., additional, Bendahman, M., additional, Benfenati, F., additional, Bertin, V., additional, Biagi, S., additional, Bissinger, M., additional, Boumaaza, J., additional, Bouta, M., additional, Bouwhuis, M. C., additional, Brânzaş, H., additional, Bruijn, R., additional, Brunner, J., additional, Busto, J., additional, Caiffi, B., additional, Calvo, D., additional, Capone, A., additional, Caramete, L., additional, Carr, J., additional, Carretero, V., additional, Celli, S., additional, Chabab, M., additional, Chau, T. N., additional, El Moursli, R. Cherkaoui, additional, Chiarusi, T., additional, Circella, M., additional, Coelho, J. A. B., additional, Coleiro, A., additional, Coniglione, R., additional, Coyle, P., additional, Creusot, A., additional, Díaz, A. F., additional, de Wasseige, G., additional, De Martino, B., additional, Distefano, C., additional, Di Palma, I., additional, Domi, A., additional, Donzaud, C., additional, Dornic, D., additional, Drouhin, D., additional, Eberl, T., additional, van Eeden, T., additional, van Eijk, D., additional, El Khayati, N., additional, Enzenhöfer, A., additional, Fermani, P., additional, Ferrara, G., additional, Filippini, F., additional, Fusco, L., additional, García, J., additional, Gay, P., additional, Glotin, H., additional, Gozzini, R., additional, Ruiz, R. Gracia, additional, Graf, K., additional, Guidi, C., additional, Hallmann, S., additional, van Haren, H., additional, Heijboer, A. J., additional, Hello, Y., additional, Hernández-Rey, J. J., additional, Hößl, J., additional, Hofestädt, J., additional, Huang, F., additional, Illuminati, G., additional, James, C. W., additional, Jisse-Jung, B., additional, de Jong, M., additional, de Jong, P., additional, Kadler, M., additional, Kalekin, O., additional, Katz, U., additional, Kouchner, A., additional, Kreykenbohm, I., additional, Kulikovskiy, V., additional, Lahmann, R., additional, Lamoureux, M., additional, Le Breton, R., additional, Lefèvre, D., additional, Leonora, E., additional, Levi, G., additional, Le Stum, S., additional, Lopez-Coto, D., additional, Loucatos, S., additional, Maderer, L., additional, Manczak, J., additional, Marcelin, M., additional, Margiotta, A., additional, Marinelli, A., additional, Martínez-Mora, J. A., additional, Melis, K., additional, Migliozzi, P., additional, Moussa, A., additional, Muller, R., additional, Nauta, L., additional, Navas, S., additional, Nezri, E., additional, Fearraigh, B. Ó, additional, Păun, A., additional, Păvălaş, G. E., additional, Pellegrino, C., additional, Perrin-Terrin, M., additional, Pestel, V., additional, Piattelli, P., additional, Pieterse, C., additional, Poirè, C., additional, Popa, V., additional, Pradier, T., additional, Randazzo, N., additional, Real, D., additional, Reck, S., additional, Riccobene, G., additional, Romanov, A., additional, Sánchez-Losa, A., additional, Samtleben, D. F. E., additional, Sanguineti, M., additional, Sapienza, P., additional, Schnabel, J., additional, Schumann, J., additional, Schüssler, F., additional, Seneca, J., additional, Spurio, M., additional, Stolarczyk, Th., additional, Taiuti, M., additional, Tayalati, Y., additional, Tingay, S. J., additional, Vallage, B., additional, Van Elewyck, V., additional, Versari, F., additional, Viola, S., additional, Vivolo, D., additional, Wilms, J., additional, Zavatarelli, S., additional, Zegarelli, A., additional, Zornoza, J. D., additional, Zúñiga, J., additional, Alvarez, C., additional, Arteaga-Velázquez, J. C., additional, Babu, R., additional, Belmont-Moreno, E., additional, Caballero-Mora, K. S., additional, Capistrán, T., additional, Carramiñana, A., additional, Casanova, S., additional, Cotti, U., additional, Chaparro-Amaro, O., additional, Cotzomi, J., additional, de León, S. Coutiño, additional, De la Fuente, E., additional, de León, C., additional, Diaz Hernandez, R., additional, DuVernois, M. A., additional, Durocher, M., additional, Díaz-Vélez, J. C., additional, Engel, K., additional, Espinoza, C., additional, Fan, K. L., additional, Alonso, M. Fernández, additional, Fraija, N., additional, García-González, J. A., additional, Garfias, F., additional, González, M. M., additional, Goodman, J. A., additional, Harding, J. P., additional, Hernandez, S., additional, Huang, D., additional, Hueyotl-Zahuantitla, F., additional, Hüntemeyer, P., additional, Iriarte, A., additional, Joshi, V., additional, Kaufmann, S., additional, Lara, A., additional, Vargas, H. León, additional, Linnemann, J. T., additional, Longinotti, A. L., additional, Luis-Raya, G., additional, Malone, K., additional, Martinez, O., additional, Martinez-Castellanos, I., additional, Martínez-Castro, J., additional, Matthews, J. A., additional, Miranda-Romagnoli, P., additional, Morales-Soto, J. A., additional, Moreno, E., additional, Nayerhoda, A., additional, Nellen, L., additional, Nisa, M. U., additional, Noriega-Papaqui, R., additional, Omodei, N., additional, Peisker, A., additional, Araujo, Y. Pérez, additional, Pérez-Pérez, E. G., additional, Rho, C. D., additional, Rosa-González, D., additional, Ruiz-Velasco, E., additional, Salazar, H., additional, Salesa Greus, F., additional, Sandoval, A., additional, Schneider, M., additional, Smith, A. J., additional, Son, Y., additional, Springer, R. W., additional, Tibolla, O., additional, Tollefson, K., additional, Torres, I., additional, Torres-Escobedo, R., additional, Turner, R., additional, Ureña-Mena, F., additional, Varela, E., additional, Wang, X., additional, Whitaker, K., additional, Willox, E., additional, Zepeda, A., additional, and Zhou, H., additional
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- 2023
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38. Sex differences in the rate of abdominal adipose accrual during adulthood: the Fels Longitudinal Study
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Whitaker, K M, Choh, A C, Lee, M, Towne, B, Czerwinski, S A, and Demerath, E W
- Published
- 2016
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39. Atlas of lesion locations and postsurgical seizure freedom in focal cortical dysplasia: A MELD study
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Wagstyl, K, Whitaker, K, Raznahan, A, Seidlitz, J, Vertes, PE, Foldes, S, Humphreys, Z, Hu, W, Mo, J, Likeman, M, Davies, S, Lenge, M, Cohen, NT, Tang, Y, Wang, S, Ripart, M, Chari, A, Tisdall, M, Bargallo, N, Conde-Blanco, E, Carlos Pariente, J, Pascual-Diaz, S, Delgado-Martinez, I, Perez-Enriquez, C, Lagorio, I, Abela, E, Mullatti, N, O'Muircheartaigh, J, Vecchiato, K, Liu, Y, Caligiuri, M, Sinclair, B, Vivash, L, Willard, A, Kandasamy, J, McLellan, A, Sokol, D, Semmelroch, M, Kloster, A, Opheim, G, Yasuda, C, Zhang, K, Hamandi, K, Barba, C, Guerrini, R, Gaillard, WD, You, X, Wang, I, Gonzalez-Ortiz, S, Severino, M, Striano, P, Tortora, D, Kalviainen, R, Gambardella, A, Labate, A, Desmond, P, Lui, E, O'Brien, T, Shetty, J, Jackson, G, Duncan, JS, Winston, GP, Pinborg, L, Cendes, F, Cross, JH, Baldeweg, T, Adler, S, Wagstyl, K, Whitaker, K, Raznahan, A, Seidlitz, J, Vertes, PE, Foldes, S, Humphreys, Z, Hu, W, Mo, J, Likeman, M, Davies, S, Lenge, M, Cohen, NT, Tang, Y, Wang, S, Ripart, M, Chari, A, Tisdall, M, Bargallo, N, Conde-Blanco, E, Carlos Pariente, J, Pascual-Diaz, S, Delgado-Martinez, I, Perez-Enriquez, C, Lagorio, I, Abela, E, Mullatti, N, O'Muircheartaigh, J, Vecchiato, K, Liu, Y, Caligiuri, M, Sinclair, B, Vivash, L, Willard, A, Kandasamy, J, McLellan, A, Sokol, D, Semmelroch, M, Kloster, A, Opheim, G, Yasuda, C, Zhang, K, Hamandi, K, Barba, C, Guerrini, R, Gaillard, WD, You, X, Wang, I, Gonzalez-Ortiz, S, Severino, M, Striano, P, Tortora, D, Kalviainen, R, Gambardella, A, Labate, A, Desmond, P, Lui, E, O'Brien, T, Shetty, J, Jackson, G, Duncan, JS, Winston, GP, Pinborg, L, Cendes, F, Cross, JH, Baldeweg, T, and Adler, S
- Abstract
OBJECTIVE: Drug-resistant focal epilepsy is often caused by focal cortical dysplasias (FCDs). The distribution of these lesions across the cerebral cortex and the impact of lesion location on clinical presentation and surgical outcome are largely unknown. We created a neuroimaging cohort of patients with individually mapped FCDs to determine factors associated with lesion location and predictors of postsurgical outcome. METHODS: The MELD (Multi-centre Epilepsy Lesion Detection) project collated a retrospective cohort of 580 patients with epilepsy attributed to FCD from 20 epilepsy centers worldwide. Magnetic resonance imaging-based maps of individual FCDs with accompanying demographic, clinical, and surgical information were collected. We mapped the distribution of FCDs, examined for associations between clinical factors and lesion location, and developed a predictive model of postsurgical seizure freedom. RESULTS: FCDs were nonuniformly distributed, concentrating in the superior frontal sulcus, frontal pole, and temporal pole. Epilepsy onset was typically before the age of 10 years. Earlier epilepsy onset was associated with lesions in primary sensory areas, whereas later epilepsy onset was associated with lesions in association cortices. Lesions in temporal and occipital lobes tended to be larger than frontal lobe lesions. Seizure freedom rates varied with FCD location, from around 30% in visual, motor, and premotor areas to 75% in superior temporal and frontal gyri. The predictive model of postsurgical seizure freedom had a positive predictive value of 70% and negative predictive value of 61%. SIGNIFICANCE: FCD location is an important determinant of its size, the age at epilepsy onset, and the likelihood of seizure freedom postsurgery. Our atlas of lesion locations can be used to guide the radiological search for subtle lesions in individual patients. Our atlas of regional seizure freedom rates and associated predictive model can be used to estimate individual l
- Published
- 2022
40. Interpretable surface-based detection of focal cortical dysplasias: a Multi-centre Epilepsy Lesion Detection study
- Author
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Spitzer, H, Ripart, M, Whitaker, K, D'Arco, F, Mankad, K, Chen, AA, Napolitano, A, De Palma, L, De Benedictis, A, Foldes, S, Humphreys, Z, Zhang, K, Hu, W, Mo, J, Likeman, M, Davies, S, Guttler, C, Lenge, M, Cohen, NT, Tang, Y, Wang, S, Chari, A, Tisdall, M, Bargallo, N, Conde-Blanco, E, Pariente, JC, Pascual-Diaz, S, Delgado-Martinez, I, Perez-Enriquez, C, Lagorio, I, Abela, E, Mullatti, N, O'Muircheartaigh, J, Vecchiato, K, Liu, Y, Caligiuri, ME, Sinclair, B, Vivash, L, Willard, A, Kandasamy, J, McLellan, A, Sokol, D, Semmelroch, M, Kloster, AG, Opheim, G, Ribeiro, L, Yasuda, C, Rossi-Espagnet, C, Hamandi, K, Tietze, A, Barba, C, Guerrini, R, Gaillard, WD, You, X, Wang, I, Gonzalez-Ortiz, S, Severino, M, Striano, P, Tortora, D, Kalviainen, R, Gambardella, A, Labate, A, Desmond, P, Lui, E, O'Brien, T, Shetty, J, Jackson, G, Duncan, JS, Winston, GP, Pinborg, LH, Cendes, F, Theis, FJ, Shinohara, RT, Cross, JH, Baldeweg, T, Adler, S, Wagstyl, K, Spitzer, H, Ripart, M, Whitaker, K, D'Arco, F, Mankad, K, Chen, AA, Napolitano, A, De Palma, L, De Benedictis, A, Foldes, S, Humphreys, Z, Zhang, K, Hu, W, Mo, J, Likeman, M, Davies, S, Guttler, C, Lenge, M, Cohen, NT, Tang, Y, Wang, S, Chari, A, Tisdall, M, Bargallo, N, Conde-Blanco, E, Pariente, JC, Pascual-Diaz, S, Delgado-Martinez, I, Perez-Enriquez, C, Lagorio, I, Abela, E, Mullatti, N, O'Muircheartaigh, J, Vecchiato, K, Liu, Y, Caligiuri, ME, Sinclair, B, Vivash, L, Willard, A, Kandasamy, J, McLellan, A, Sokol, D, Semmelroch, M, Kloster, AG, Opheim, G, Ribeiro, L, Yasuda, C, Rossi-Espagnet, C, Hamandi, K, Tietze, A, Barba, C, Guerrini, R, Gaillard, WD, You, X, Wang, I, Gonzalez-Ortiz, S, Severino, M, Striano, P, Tortora, D, Kalviainen, R, Gambardella, A, Labate, A, Desmond, P, Lui, E, O'Brien, T, Shetty, J, Jackson, G, Duncan, JS, Winston, GP, Pinborg, LH, Cendes, F, Theis, FJ, Shinohara, RT, Cross, JH, Baldeweg, T, Adler, S, and Wagstyl, K
- Abstract
One outstanding challenge for machine learning in diagnostic biomedical imaging is algorithm interpretability. A key application is the identification of subtle epileptogenic focal cortical dysplasias (FCDs) from structural MRI. FCDs are difficult to visualize on structural MRI but are often amenable to surgical resection. We aimed to develop an open-source, interpretable, surface-based machine-learning algorithm to automatically identify FCDs on heterogeneous structural MRI data from epilepsy surgery centres worldwide. The Multi-centre Epilepsy Lesion Detection (MELD) Project collated and harmonized a retrospective MRI cohort of 1015 participants, 618 patients with focal FCD-related epilepsy and 397 controls, from 22 epilepsy centres worldwide. We created a neural network for FCD detection based on 33 surface-based features. The network was trained and cross-validated on 50% of the total cohort and tested on the remaining 50% as well as on 2 independent test sites. Multidimensional feature analysis and integrated gradient saliencies were used to interrogate network performance. Our pipeline outputs individual patient reports, which identify the location of predicted lesions, alongside their imaging features and relative saliency to the classifier. On a restricted 'gold-standard' subcohort of seizure-free patients with FCD type IIB who had T1 and fluid-attenuated inversion recovery MRI data, the MELD FCD surface-based algorithm had a sensitivity of 85%. Across the entire withheld test cohort the sensitivity was 59% and specificity was 54%. After including a border zone around lesions, to account for uncertainty around the borders of manually delineated lesion masks, the sensitivity was 67%. This multicentre, multinational study with open access protocols and code has developed a robust and interpretable machine-learning algorithm for automated detection of focal cortical dysplasias, giving physicians greater confidence in the identification of subtle MRI lesions in
- Published
- 2022
41. Donor and Peri-Transplant Hospitalization Risk Factors for Invasive Fungal Infection in Lung Transplant Recipients
- Author
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Le Mahajan, A., primary, Whitaker, K., additional, Blumberg, E., additional, Gardo, L., additional, Lee, J., additional, Crespo, M., additional, Bermudez, C., additional, Glaser, L., additional, Wilck, M., additional, and Anesi, J., additional
- Published
- 2022
- Full Text
- View/download PDF
42. Emotional responses to the experience of cancer ‘alarm’ symptoms
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Whitaker, K. L., Cromme, S., Winstanley, K., Renzi, C., and Wardle, J.
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- 2016
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- View/download PDF
43. (976) - Letermovir Use Following Lung Transplantation: A Single Center Review
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He, K.D., Whitaker, K., Blumberg, E., Crespo, M., and Courtwright, A.
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- 2024
- Full Text
- View/download PDF
44. Inter-annual and seasonal trends in cetacean distribution, density and abundance off southern California
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Campbell, GS, Thomas, L, Whitaker, K, Douglas, AB, Calambokidis, J, and Hildebrand, JA
- Subjects
Cetaceans ,Line transect ,Density ,Abundance ,Distribution ,Trends ,Southern California ,CalCOFI ,Oceanography ,Geochemistry ,Ecology - Abstract
Trends in cetacean density and distribution off southern California were assessed through visual line-transect surveys during thirty-seven California Cooperative Oceanic Fisheries Investigations (CalCOFI) cruises from July 2004-November 2013. From sightings of the six most commonly encountered cetacean species, seasonal, annual and overall density estimates were calculated. Blue whales (Balaenoptera musculus), fin whales (Balaenoptera physalus) and humpback whales (Megaptera novaeangliae) were the most frequently sighted baleen whales with overall densities of 0.91/1000km2 (CV=0.27), 2.73/1000km2 (CV=0.19), and 1.17/1000km2 (CV=0.21) respectively. Species specific density estimates, stratified by cruise, were analyzed using a generalized additive model to estimate long-term trends and correct for seasonal imbalances. Variances were estimated using a non-parametric bootstrap with one day of effort as the sampling unit. Blue whales were primarily observed during summer and fall while fin and humpback whales were observed year-round with peaks in density during summer and spring respectively. Short-beaked common dolphins (Delphinus delphis), Pacific white-sided dolphins (Lagenorhynchus obliquidens) and Dall's porpoise (Phocoenoidesdalli) were the most frequently encountered small cetaceans with overall densities of 705.83/1000km2 (CV=0.22), 51.98/1000km2 (CV=0.27), and 21.37/1000km2 (CV=0.19) respectively. Seasonally, short-beaked common dolphins were most abundant in winter whereas Pacific white-sided dolphins and Dall's porpoise were most abundant during spring. There were no significant long-term changes in blue whale, fin whale, humpback whale, short-beaked common dolphin or Dall's porpoise densities while Pacific white-sided dolphins exhibited a significant decrease in density across the ten-year study. The results from this study were fundamentally consistent with earlier studies, but provide greater temporal and seasonal resolution.
- Published
- 2015
45. Knowledge of cancer warning signs and reported helpseeking in a community sample: Abstract O-04
- Author
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Whitaker, K. L., Winstanley, K., Macleod, U., Scott, S. E., and Wardle, J.
- Published
- 2015
46. Effect of magnesium sulfate exposure on term neonates
- Author
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Greenberg, M B, Penn, A A, Whitaker, K R, Kogut, E A, El-Sayed, Y Y, Caughey, A B, and Lyell, D J
- Published
- 2013
- Full Text
- View/download PDF
47. Tsaur Jyr and the Introduction of Fannbay 梵 唄 into China
- Author
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Whitaker, K. P. K.
- Published
- 1957
48. Some Notes on the Authorship of the Lii Ling/Su Wuu Letters--II
- Author
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Whitaker, K. P. K.
- Published
- 1953
49. Tsaur Jyr's Song of the Ill-Fated Lady 曹 植: 妾 薄 命 行
- Author
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Whitaker, K. P. K.
- Published
- 1955
50. Some Notes on the Background and Date of Tsaur Jyr's Poem on the Three Good Courtiers
- Author
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Whitaker, K. P. K.
- Published
- 1956
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