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509 results on '"Whybrow, Peter C."'

3. Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder

Author

Bauer, Michael, Glenn, Tasha, Achtyes, Eric D., Alda, Martin, Agaoglu, Esen, Altınbaş, Kürsat, Andreassen, Ole A., Angelopoulos, Elias, Ardau, Raffaella, Aydin, Memduha, Ayhan, Yavuz, Baethge, Christopher, Bauer, Rita, Baune, Bernhard T., Balaban, Ceylan, Becerra-Palars, Claudia, Behere, Aniruddh P., Behere, Prakash B., Belete, Habte, Belete, Tilahun, Belizario, Gabriel Okawa, Bellivier, Frank, Belmaker, Robert H., Benedetti, Francesco, Berk, Michael, Bersudsky, Yuly, Bicakci, Şule, Birabwa-Oketcho, Harriet, Bjella, Thomas D., Brady, Conan, Cabrera, Jorge, Cappucciati, Marco, Castro, Angela Marianne Paredes, Chen, Wei-Ling, Cheung, Eric Y. W., Chiesa, Silvia, Crowe, Marie, Cuomo, Alessandro, Dallaspezia, Sara, Del Zompo, Maria, Desai, Pratikkumar, Dodd, Seetal, Etain, Bruno, Fagiolini, Andrea, Fellendorf, Frederike T., Ferensztajn-Rochowiak, Ewa, Fiedorowicz, Jess G., Fountoulakis, Kostas N., Frye, Mark A., Geoffroy, Pierre A., Gitlin, Michael J., Gonzalez-Pinto, Ana, Gottlieb, John F., Grof, Paul, Haarman, Bartholomeus C. M., Harima, Hirohiko, Hasse-Sousa, Mathias, Henry, Chantal, Hoffding, Lone, Houenou, Josselin, Imbesi, Massimiliano, Isometsä, Erkki T., Ivkovic, Maja, Janno, Sven, Johnsen, Simon, Kapczinski, Flávio, Karakatsoulis, Gregory N., Kardell, Mathias, Kessing, Lars Vedel, Kim, Seong Jae, König, Barbara, Kot, Timur L., Koval, Michael, Kunz, Mauricio, Lafer, Beny, Landén, Mikael, Larsen, Erik R., Lenger, Melanie, Licht, Rasmus W., Lopez-Jaramillo, Carlos, MacKenzie, Alan, Madsen, Helle Østergaard, Madsen, Simone Alberte Kongstad A., Mahadevan, Jayant, Mahardika, Agustine, Manchia, Mirko, Marsh, Wendy, Martinez-Cengotitabengoa, Monica, Martini, Julia, Martiny, Klaus, Mashima, Yuki, McLoughlin, Declan M., Meesters, Ybe, Melle, Ingrid, Meza-Urzúa, Fátima, Mikolas, Pavol, Mok, Yee Ming, Monteith, Scott, Moorthy, Muthukumaran, Morken, Gunnar, Mosca, Enrica, Mozzhegorov, Anton A., Munoz, Rodrigo, Mythri, Starlin V., Nacef, Fethi, Nadella, Ravi K., Nakanotani, Takako, Nielsen, René Ernst, O’Donovan, Claire, Omrani, Adel, Osher, Yamima, Ouali, Uta, Pantovic-Stefanovic, Maja, Pariwatcharakul, Pornjira, Petite, Joanne, Petzold, Johannes, Pfennig, Andrea, Ruiz, Yolanda Pica, Pinna, Marco, Pompili, Maurizio, Porter, Richard J., Quiroz, Danilo, Rabelo-da-Ponte, Francisco Diego, Ramesar, Raj, Rasgon, Natalie, Ratta-apha, Woraphat, Ratzenhofer, Michaela, Redahan, Maria, Reddy, M. S., Reif, Andreas, Reininghaus, Eva Z., Richards, Jenny Gringer, Ritter, Philipp, Rybakowski, Janusz K., Sathyaputri, Leela, Scippa, Angela M., Simhandl, Christian, Smith, Daniel, Smith, José, Stackhouse, Jr, Paul W., Stein, Dan J., Stilwell, Kellen, Strejilevich, Sergio, Su, Kuan-Pin, Subramaniam, Mythily, Sulaiman, Ahmad Hatim, Suominen, Kirsi, Tanra, Andi J., Tatebayashi, Yoshitaka, Teh, Wen Lin, Tondo, Leonardo, Torrent, Carla, Tuinstra, Daniel, Uchida, Takahito, Vaaler, Arne E., Vieta, Eduard, Viswanath, Biju, Yoldi-Negrete, Maria, Yalcinkaya, Oguz Kaan, Young, Allan H., Zgueb, Yosra, and Whybrow, Peter C.

Published
2023
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5. Dynamic coupling of whole-brain neuronal and neurotransmitter systems

Author

Kringelbach, Morten L, Cruzat, Josephine, Cabral, Joana, Knudsen, Gitte Moos, Carhart-Harris, Robin, Whybrow, Peter C, Logothetis, Nikos K, and Deco, Gustavo

Subjects
Depression, Biomedical Imaging, Bioengineering, Mental Health, Neurosciences, Brain Disorders, 1.1 Normal biological development and functioning, Underpinning research, Mental health, Neurological, Brain, Computer Simulation, Models, Biological, Neurons, Neurotransmitter Agents, serotonin, PET, psilocybin, neurotransmitter, whole-brain modeling
Abstract

Remarkable progress has come from whole-brain models linking anatomy and function. Paradoxically, it is not clear how a neuronal dynamical system running in the fixed human anatomical connectome can give rise to the rich changes in the functional repertoire associated with human brain function, which is impossible to explain through long-term plasticity. Neuromodulation evolved to allow for such flexibility by dynamically updating the effectivity of the fixed anatomical connectivity. Here, we introduce a theoretical framework modeling the dynamical mutual coupling between the neuronal and neurotransmitter systems. We demonstrate that this framework is crucial to advance our understanding of whole-brain dynamics by bidirectional coupling of the two systems through combining multimodal neuroimaging data (diffusion magnetic resonance imaging [dMRI], functional magnetic resonance imaging [fMRI], and positron electron tomography [PET]) to explain the functional effects of specific serotoninergic receptor (5-HT2AR) stimulation with psilocybin in healthy humans. This advance provides an understanding of why psilocybin is showing considerable promise as a therapeutic intervention for neuropsychiatric disorders including depression, anxiety, and addiction. Overall, these insights demonstrate that the whole-brain mutual coupling between the neuronal and the neurotransmission systems is essential for understanding the remarkable flexibility of human brain function despite having to rely on fixed anatomical connectivity.

Published
2020

7. Association between polarity of first episode and solar insolation in bipolar I disorder

Author

Bauer, Michael, Glenn, Tasha, Achtyes, Eric D., Alda, Martin, Agaoglu, Esen, Altınbaş, Kürşat, Andreassen, Ole A., Angelopoulos, Elias, Ardau, Raffaella, Aydin, Memduha, Ayhan, Yavuz, Baethge, Christopher, Bauer, Rita, Baune, Bernhard T., Balaban, Ceylan, Becerra-Palars, Claudia, Behere, Aniruddh P., Behere, Prakash B., Belete, Habte, Belete, Tilahun, Belizario, Gabriel Okawa, Bellivier, Frank, Belmaker, Robert H., Benedetti, Francesco, Berk, Michael, Bersudsky, Yuly, Bicakci, Şule, Birabwa-Oketcho, Harriet, Bjella, Thomas D., Brady, Conan, Cabrera, Jorge, Cappucciati, Marco, Castro, Angela Marianne Paredes, Chen, Wei-Ling, Cheung, Eric Y.W., Chiesa, Silvia, Crowe, Marie, Cuomo, Alessandro, Dallaspezia, Sara, Del Zompo, Maria, Desai, Pratikkumar, Dodd, Seetal, Etain, Bruno, Fagiolini, Andrea, Fellendorf, Frederike T., Ferensztajn-Rochowiak, Ewa, Fiedorowicz, Jess G., Fountoulakis, Kostas N., Frye, Mark A., Geoffroy, Pierre A., Gonzalez-Pinto, Ana, Gottlieb, John F., Grof, Paul, Haarman, Bartholomeus C.M., Harima, Hirohiko, Hasse-Sousa, Mathias, Henry, Chantal, Høffding, Lone, Houenou, Josselin, Imbesi, Massimiliano, Isometsä, Erkki T., Ivkovic, Maja, Janno, Sven, Johnsen, Simon, Kapczinski, Flávio, Karakatsoulis, Gregory N., Kardell, Mathias, Kessing, Lars Vedel, Kim, Seong Jae, König, Barbara, Kot, Timur L., Koval, Michael, Kunz, Mauricio, Lafer, Beny, Landén, Mikael, Larsen, Erik R., Lenger, Melanie, Lewitzka, Ute, Licht, Rasmus W., Lopez-Jaramillo, Carlos, MacKenzie, Alan, Madsen, Helle Østergaard, Madsen, Simone Alberte Kongstad A., Mahadevan, Jayant, Mahardika, Agustine, Manchia, Mirko, Marsh, Wendy, Martinez-Cengotitabengoa, Monica, Martiny, Klaus, Mashima, Yuki, McLoughlin, Declan M., Meesters, Ybe, Melle, Ingrid, Meza-Urzúa, Fátima, Mok, Yee Ming, Monteith, Scott, Moorthy, Muthukumaran, Morken, Gunnar, Mosca, Enrica, Mozzhegorov, Anton A., Munoz, Rodrigo, Mythri, Starlin V., Nacef, Fethi, Nadella, Ravi K., Nakanotani, Takako, Nielsen, René Ernst, O'Donovan, Claire, Omrani, Adel, Osher, Yamima, Ouali, Uta, Pantovic-Stefanovic, Maja, Pariwatcharakul, Pornjira, Petite, Joanne, Pfennig, Andrea, Ruiz, Yolanda Pica, Pinna, Marco, Pompili, Maurizio, Porter, Richard, Quiroz, Danilo, Rabelo-da-Ponte, Francisco Diego, Ramesar, Raj, Rasgon, Natalie, Ratta-apha, Woraphat, Ratzenhofer, Michaela, Redahan, Maria, Reddy, M.S., Reif, Andreas, Reininghaus, Eva Z., Richards, Jenny Gringer, Ritter, Philipp, Rybakowski, Janusz K., Sathyaputri, Leela, Scippa, Ângela M., Simhandl, Christian, Smith, Daniel, Smith, José, Stackhouse, Paul W., Jr., Stein, Dan J., Stilwell, Kellen, Strejilevich, Sergio, Su, Kuan-Pin, Subramaniam, Mythily, Sulaiman, Ahmad Hatim, Suominen, Kirsi, Tanra, Andi J., Tatebayashi, Yoshitaka, Teh, Wen Lin, Tondo, Leonardo, Torrent, Carla, Tuinstra, Daniel, Uchida, Takahito, Vaaler, Arne E., Vieta, Eduard, Viswanath, Biju, Yoldi-Negrete, Maria, Yalcinkaya, Oguz Kaan, Young, Allan H., Zgueb, Yosra, and Whybrow, Peter C.

Published
2022
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9. Adjunctive thyroid hormone treatment in rapid cycling bipolar disorder: A double‐blind placebo‐controlled trial of levothyroxine (L‐T4) and triiodothyronine (T3)

Author

Walshaw, Patricia D, Gyulai, Laszlo, Bauer, Michael, Bauer, Mark S, Calimlim, Brian, Sugar, Catherine A, and Whybrow, Peter C

Subjects
Clinical Trials and Supportive Activities, Brain Disorders, Depression, Mental Health, Clinical Research, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Mental health, Adult, Affect, Bipolar Disorder, Double-Blind Method, Female, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, Thyroid Function Tests, Thyroid Hormones, Thyroxine, Time Factors, Treatment Outcome, Triiodothyronine, bipolar disorder, levothyroxine, rapid cycling, thyroid, triiodothyronine, Clinical Sciences, Neurosciences, Psychiatry
Abstract

ObjectivesThis report describes the first comparative double-blind, placebo-controlled trial of levothyroxine (L-T4 ) and triiodothyronine (T3 ) as adjunctive treatments in rapid cycling bipolar disorder.MethodsThirty-two treatment-resistant, rapid cycling patients who had failed a trial of lithium were randomized into three treatment arms: L-T4 , T3 , or placebo. They were followed for ≥4 months with weekly clinical and endocrine assessments.ResultsThere were no statistically significant differences between the groups in age, gender, duration of illness, or thyroid status. Markov chain analyses were employed to assess treatment effects on cycling patterns among mood states (euthymia, depression, mania, and mixed). Within groups, post-treatment the L-T4 group spent significantly less time depressed or in a mixed state and greater time euthymic. The T3 and placebo groups did not differ significantly pre- and post-treatment in any mood state, although the pattern of effects was the same for the T3 group as for the L-T4 group. Between groups, the L-T4 group had a significantly greater increase in time euthymic and decrease in time in the mixed state than the placebo group. Other group differences were not significant, although they were in the expected direction.ConclusionsThe findings in this first double-blind study directly comparing the effects of L-T4 and T3 therapy against placebo provide evidence for the benefit of adjunctive L-T4 in alleviating resistant depression, reducing time in mixed states and increasing time euthymic. Adjunctive T3 did not show statistically significant evidence of benefit over placebo in reducing the time spent in disturbed mood states.

Published
2018

12. Artificial intelligence and cybercrime: implications for individuals and the healthcare sector.

Author

Monteith, Scott, Glenn, Tasha, Geddes, John R., Achtyes, Eric D., Whybrow, Peter C., and Bauer, Michael

Subjects
MENTAL health services, MEDICAL informatics, PEOPLE with mental illness, ARTIFICIAL intelligence, HEALTH risk assessment
Abstract

Summary: The malicious use of artificial intelligence is growing rapidly, creating major security threats for individuals and the healthcare sector. Individuals with mental illness may be especially vulnerable. Healthcare provider data are a prime target for cybercriminals. There is a need to improve cybersecurity to detect and prevent cyberattacks against individuals and the healthcare sector, including the use of artificial intelligence predictive tools. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Variations in seasonal solar insolation are associated with a history of suicide attempts in bipolar I disorder

Author

Bauer, Michael, Glenn, Tasha, Achtyes, Eric D., Alda, Martin, Agaoglu, Esen, Altınbaş, Kürşat, Andreassen, Ole A., Angelopoulos, Elias, Ardau, Raffaella, Vares, Edgar Arrua, Aydin, Memduha, Ayhan, Yavuz, Baethge, Christopher, Bauer, Rita, Baune, Bernhard T., Balaban, Ceylan, Becerra-Palars, Claudia, Behere, Aniruddh P., Behere, Prakash B., Belete, Habte, Belete, Tilahun, Belizario, Gabriel Okawa, Bellivier, Frank, Belmaker, Robert H., Benedetti, Francesco, Berk, Michael, Bersudsky, Yuly, Bicakci, Şule, Birabwa-Oketcho, Harriet, Bjella, Thomas D., Brady, Conan, Cabrera, Jorge, Cappucciati, Marco, Castro, Angela Marianne Paredes, Chen, Wei-Ling, Cheung, Eric Y. Wo, Chiesa, Silvia, Crowe, Marie, Cuomo, Alessandro, Dallaspezia, Sara, Del Zompo, Maria, Desai, Pratikkumar, Dodd, Seetal, Donix, Markus, Etain, Bruno, Fagiolini, Andrea, Fellendorf, Frederike T., Ferensztajn-Rochowiak, Ewa, Fiedorowicz, Jess G., Fountoulakis, Kostas N., Frye, Mark A., Geoffroy, Pierre A., Gonzalez-Pinto, Ana, Gottlieb, John F., Grof, Paul, Haarman, Bartholomeus C. M., Harima, Hirohiko, Hasse-Sousa, Mathias, Henry, Chantal, Høffding, Lone, Houenou, Josselin, Imbesi, Massimiliano, Isometsä, Erkki T., Ivkovic, Maja, Janno, Sven, Johnsen, Simon, Kapczinski, Flávio, Karakatsoulis, Gregory N., Kardell, Mathias, Kessing, Lars Vedel, Kim, Seong Jae, König, Barbara, Kot, Timur L., Koval, Michael, Kunz, Mauricio, Lafer, Beny, Landén, Mikael, Larsen, Erik R., Lenger, Melanie, Lewitzka, Ute, Licht, Rasmus W., Lopez-Jaramillo, Carlos, MacKenzie, Alan, Madsen, Helle Østergaard, Madsen, Simone Alberte Kongstad A., Mahadevan, Jayant, Mahardika, Agustine, Manchia, Mirko, Marsh, Wendy, Martinez-Cengotitabengoa, Monica, Martiny, Klaus, Mashima, Yuki, McLoughlin, Declan M., Meesters, Ybe, Melle, Ingrid, Meza-Urzúa, Fátima, Ming, Mok Yee, Monteith, Scott, Moorthy, Muthukumaran, Morken, Gunnar, Mosca, Enrica, Mozzhegorov, Anton A., Munoz, Rodrigo, Mythri, Starlin V., Nacef, Fethi, Nadella, Ravi K., Nakanotani, Takako, Nielsen, René Ernst, O‘Donovan, Claire, Omrani, Adel, Osher, Yamima, Ouali, Uta, Pantovic-Stefanovic, Maja, Pariwatcharakul, Pornjira, Petite, Joanne, Pfennig, Andrea, Ruiz, Yolanda Pica, Pilhatsch, Maximilian, Pinna, Marco, Pompili, Maurizio, Porter, Richard, Quiroz, Danilo, Rabelo-da-Ponte, Francisco Diego, Ramesar, Raj, Rasgon, Natalie, Ratta-apha, Woraphat, Ratzenhofer, Michaela, Redahan, Maria, Reddy, M. S., Reif, Andreas, Reininghaus, Eva Z., Richards, Jenny Gringer, Ritter, Philipp, Rybakowski, Janusz K., Sathyaputri, Leela, Scippa, Ângela M., Simhandl, Christian, Severus, Emanuel, Smith, Daniel, Smith, José, Stackhouse, Jr., Paul W., Stein, Dan J., Stilwell, Kellen, Strejilevich, Sergio, Su, Kuan-Pin, Subramaniam, Mythily, Sulaiman, Ahmad Hatim, Suominen, Kirsi, Tanra, Andi J., Tatebayashi, Yoshitaka, Teh, Wen Lin, Tondo, Leonardo, Torrent, Carla, Tuinstra, Daniel, Uchida, Takahito, Vaaler, Arne E., Veeh, Julia, Vieta, Eduard, Viswanath, Biju, Yoldi-Negrete, Maria, Yalcinkaya, Oguz Kaan, Young, Allan H., Zgueb, Yosra, and Whybrow, Peter C.

Published
2021
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15. Association between solar insolation and a history of suicide attempts in bipolar I disorder

Author

Bauer, Michael, Glenn, Tasha, Alda, Martin, Andreassen, Ole A., Angelopoulos, Elias, Ardau, Raffaella, Ayhan, Yavuz, Baethge, Christopher, Bauer, Rita, Baune, Bernhard T., Becerra-Palars, Claudia, Bellivier, Frank, Belmaker, Robert H., Berk, Michael, Bersudsky, Yuly, Bicakci, Şule, Birabwa-Oketcho, Harriet, Bjella, Thomas D., Cabrera, Jorge, Wo Cheung, Eric Y., Del Zompo, Maria, Dodd, Seetal, Donix, Markus, Etain, Bruno, Fagiolini, Andrea, Fountoulakis, Kostas N., Frye, Mark A., Gonzalez-Pinto, Ana, Gottlieb, John F., Grof, Paul, Harima, Hirohiko, Henry, Chantal, Isometsä, Erkki T., Janno, Sven, Kapczinski, Flávio, Kardell, Mathias, Khaldi, Slim, Kliwicki, Sebastian, König, Barbara, Kot, Timur L., Krogh, Rikke, Kunz, Mauricio, Lafer, Beny, Landén, Mikael, Larsen, Erik R., Lewitzka, Ute, Licht, Rasmus W., Lopez-Jaramillo, Carlos, MacQueen, Glenda, Manchia, Mirko, Marsh, Wendy, Martinez-Cengotitabengoa, Mónica, Melle, Ingrid, Meza-Urzúa, Fátima, Ming, Mok Yee, Monteith, Scott, Morken, Gunnar, Mosca, Enrica, Mozzhegorov, Anton A., Munoz, Rodrigo, Mythri, Starlin V., Nacef, Fethi, Nadella, Ravi K., Nery, Fabiano G., Nielsen, René E., O'Donovan, Claire, Omrani, Adel, Osher, Yamima, Sørensen, Helle Østermark, Ouali, Uta, Ruiz, Yolanda Pica, Pilhatsch, Maximilian, Pinna, Marco, da Ponte, Francisco D.R., Quiroz, Danilo, Ramesar, Raj, Rasgon, Natalie, Reddy, M.S., Reif, Andreas, Ritter, Philipp, Rybakowski, Janusz K., Sagduyu, Kemal, Raghuraman, Bharathram Sathur, Scippa, Ângela M., Severus, Emanuel, Simhandl, Christian, Stackhouse, Paul W., Jr., Stein, Dan J., Strejilevich, Sergio, Subramaniam, Mythily, Sulaiman, Ahmad Hatim, Suominen, Kirsi, Tagata, Hiromi, Tatebayashi, Yoshitaka, Tondo, Leonardo, Torrent, Carla, Vaaler, Arne E., Vares, Edgar, Veeh, Julia, Vieta, Eduard, Viswanath, Biju, Yoldi-Negrete, Maria, Zetin, Mark, Zgueb, Yosra, and Whybrow, Peter C.

Published
2019
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24. One ring to rule them all: the unifying role of prefrontal cortex in steering task-related brain dynamics

Author

Universitat Politècnica de Catalunya. Departament de Matemàtiques, Deco, Gustavo, Sanz Perl, Yonatan, Ponce Álvarez, Adrián Fernando, Tagliazucchi, Enzo, Whybrow, Peter C, Fuster, Joaquín, Kringelbach, Morten L., Universitat Politècnica de Catalunya. Departament de Matemàtiques, Deco, Gustavo, Sanz Perl, Yonatan, Ponce Álvarez, Adrián Fernando, Tagliazucchi, Enzo, Whybrow, Peter C, Fuster, Joaquín, and Kringelbach, Morten L.

Abstract

Surviving and thriving in a complex world require intricate balancing of higher order brain functions with essential survival-related behaviours. Exactly how this is achieved is not fully understood but a large body of work has shown that different regions in the prefrontal cortex (PFC) play key roles for diverse cognitive and emotional tasks including emotion, control, response inhibition, mental set shifting and working memory. We hypothesised that the key regions are hierarchically organised and we developed a framework for discovering the driving brain regions at the top of the hierarchy, responsible for steering the brain dynamics of higher brain function. We fitted a time-dependent whole-brain model to the neuroimaging data from large-scale Human Connectome Project with over 1000 participants and computed the entropy production for rest and seven tasks (covering the main domains of cognition). This thermodynamics framework allowed us to identify the main common, unifying drivers steering the orchestration of brain dynamics during difficult tasks; located in key regions of the PFC (inferior frontal gyrus, lateral orbitofrontal cortex, rostral and caudal frontal cortex and rostral anterior cingulate cortex). Selectively lesioning these regions in the whole-brain model demonstrated their causal mechanistic importance. Overall, this shows the existence of a 'ring' of specific PFC regions ruling over the orchestration of higher brain function., G.D. is supported by the Human Brain Project Specific Grant Agreement 3 Grant agreement no. 945539 and by the Spanish Research Project AWAKENING: using whole-brain models perturbational approaches for predicting external stimulation to force transitions between different brain states, ref. PID2019–105772GB-I00/AEI/10.13039/ 501100011033, financed by the Spanish Ministry of Science, Innovation and Universities (MCIU), State Research Agency (AEI). Y.S.P is supported by European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant 896354. E.T is supported by grants PICT-2018–03103 and PICT-2019–02294 funded by Agencia I+D+I (Argentina) and by a Mercator fellowship granted by the German Research Foundation. M.L.K. is supported by the Centre for Eudaimonia and Human Flourishing (funded by the Pettit and Carlsberg Foundations) and Center for Music in the Brain (funded by the Danish National Research Foundation, DNRF117)., Peer Reviewed, Postprint (published version)

Published
2023

25. Internet use by patients with bipolar disorder: Results from an international multisite survey

Author

Bauer, Rita, Conell, Jörn, Glenn, Tasha, Alda, Martin, Ardau, Raffaella, Baune, Bernhard T., Berk, Michael, Bersudsky, Yuly, Bilderbeck, Amy, Bocchetta, Alberto, Bossini, Letizia, Castro, Angela M. Paredes, Cheung, Eric YW., Chillotti, Caterina, Choppin, Sabine, Del Zompo, Maria, Dias, Rodrigo, Dodd, Seetal, Duffy, Anne, Etain, Bruno, Fagiolini, Andrea, Hernandez, Miryam Fernández, Garnham, Julie, Geddes, John, Gildebro, Jonas, Gonzalez-Pinto, Ana, Goodwin, Guy M., Grof, Paul, Harima, Hirohiko, Hassel, Stefanie, Henry, Chantal, Hidalgo-Mazzei, Diego, Kapur, Vaisnvy, Kunigiri, Girish, Lafer, Beny, Larsen, Erik R., Lewitzka, Ute, Licht, Rasmus W., Lund, Anne Hvenegaard, Misiak, Blazej, Monteith, Scott, Munoz, Rodrigo, Nakanotani, Takako, Nielsen, René E, O’Donovan, Claire, Okamura, Yasushi, Osher, Yamima, Piotrowski, Patryk, Reif, Andreas, Ritter, Philipp, Rybakowski, Janusz K., Sagduyu, Kemal, Sawchuk, Brett, Schwartz, Elon, Scippa, Ângela M., Slaney, Claire, Sulaiman, Ahmad H., Suominen, Kirsi, Suwalska, Aleksandra, Tam, Peter, Tatebayashi, Yoshitaka, Tondo, Leonardo, Vieta, Eduard, Vinberg, Maj, Viswanath, Biju, Volkert, Julia, Zetin, Mark, Whybrow, Peter C., and Bauer, Michael

Published
2016
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28. Influence of light exposure during early life on the age of onset of bipolar disorder

Author

Bauer, Michael, Glenn, Tasha, Alda, Martin, Andreassen, Ole A., Angelopoulos, Elias, Ardau, Raffaella, Baethge, Christopher, Bauer, Rita, Baune, Bernhard T., Bellivier, Frank, Belmaker, Robert H., Berk, Michael, Bjella, Thomas D., Bossini, Letizia, Bersudsky, Yuly, Wo Cheung, Eric Yat, Conell, Jörn, Del Zompo, Maria, Dodd, Seetal, Etain, Bruno, Fagiolini, Andrea, Frye, Mark A., Fountoulakis, Kostas N., Garneau-Fournier, Jade, Gonzalez-Pinto, Ana, Gottlieb, John F., Harima, Hirohiko, Hassel, Stefanie, Henry, Chantal, Iacovides, Apostolos, Isometsä, Erkki T., Kapczinski, Flávio, Kliwicki, Sebastian, König, Barbara, Krogh, Rikke, Kunz, Mauricio, Lafer, Beny, Larsen, Erik R., Lewitzka, Ute, Lopez-Jaramillo, Carlos, MacQueen, Glenda, Manchia, Mirko, Marsh, Wendy, Martinez-Cengotitabengoa, Mónica, Melle, Ingrid, Monteith, Scott, Morken, Gunnar, Munoz, Rodrigo, Nery, Fabiano G., O'Donovan, Claire, Osher, Yamima, Pfennig, Andrea, Quiroz, Danilo, Ramesar, Raj, Rasgon, Natalie, Reif, Andreas, Ritter, Philipp, Rybakowski, Janusz K., Sagduyu, Kemal, Miranda- Scippa, Ângela, Severus, Emanuel, Simhandl, Christian, Stein, Dan J., Strejilevich, Sergio, Sulaiman, Ahmad Hatim, Suominen, Kirsi, Tagata, Hiromi, Tatebayashi, Yoshitaka, Torrent, Carla, Vieta, Eduard, Viswanath, Biju, Wanchoo, Mihir J., Zetin, Mark, and Whybrow, Peter C.

Published
2015
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31. Relationship between sunlight and the age of onset of bipolar disorder: An international multisite study

Author

Bauer, Michael, Glenn, Tasha, Alda, Martin, Andreassen, Ole A., Angelopoulos, Elias, Ardau, Raffaella, Baethge, Christopher, Bauer, Rita, Bellivier, Frank, Belmaker, Robert H., Berk, Michael, Bjella, Thomas D., Bossini, Letizia, Bersudsky, Yuly, Cheung, Eric Yat Wo, Conell, Jörn, Zompo, Maria Del, Dodd, Seetal, Etain, Bruno, Fagiolini, Andrea, Frye, Mark A., Fountoulakis, Kostas N., Garneau-Fournier, Jade, González-Pinto, Ana, Harima, Hirohiko, Hassel, Stefanie, Henry, Chantal, Iacovides, Apostolos, Isometsä, Erkki T., Kapczinski, Flávio, Kliwicki, Sebastian, König, Barbara, Krogh, Rikke, Kunz, Mauricio, Lafer, Beny, Larsen, Erik R., Lewitzka, Ute, Lopez-Jaramillo, Carlos, MacQueen, Glenda, Manchia, Mirko, Marsh, Wendy, Martinez-Cengotitabengoa, Mónica, Melle, Ingrid, Monteith, Scott, Morken, Gunnar, Munoz, Rodrigo, Nery, Fabiano G., O’Donovan, Claire, Osher, Yamima, Pfennig, Andrea, Quiroz, Danilo, Ramesar, Raj, Rasgon, Natalie, Reif, Andreas, Ritter, Philipp, Rybakowski, Janusz K., Sagduyu, Kemal, Scippa, Ângela M., Severus, Emanuel, Simhandl, Christian, Stein, Dan J., Strejilevich, Sergio, Hatim Sulaiman, Ahmad, Suominen, Kirsi, Tagata, Hiromi, Tatebayashi, Yoshitaka, Torrent, Carla, Vieta, Eduard, Viswanath, Biju, Wanchoo, Mihir J., Zetin, Mark, and Whybrow, Peter C.

Published
2014
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32. Artificial intelligence and increasing misinformation.

Author

Monteith, Scott, Glenn, Tasha, Geddes, John R., Whybrow, Peter C., Achtyes, Eric, and Bauer, Michael

Subjects
ARTIFICIAL intelligence, GENERATIVE artificial intelligence, LANGUAGE models, MISINFORMATION, CHATGPT
Abstract

Summary: With the recent advances in artificial intelligence (AI), patients are increasingly exposed to misleading medical information. Generative AI models, including large language models such as ChatGPT, create and modify text, images, audio and video information based on training data. Commercial use of generative AI is expanding rapidly and the public will routinely receive messages created by generative AI. However, generative AI models may be unreliable, routinely make errors and widely spread misinformation. Misinformation created by generative AI about mental illness may include factual errors, nonsense, fabricated sources and dangerous advice. Psychiatrists need to recognise that patients may receive misinformation online, including about medicine and psychiatry. [ABSTRACT FROM AUTHOR]

Published
2024
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33. Longitudinal Digital Mood Charting in Bipolar Disorder: Experiences with ChronoRecord Over 20 Years.

Author

Bauer, Michael, Glenn, Tasha, Alda, Martin, Grof, Paul, Bauer, Rita, Ebner-Priemer, Ulrich W., Ehrlich, Stefan, Pfennig, Andrea, Pilhatsch, Maximilian, Rasgon, Natalie, and Whybrow, Peter C.

Subjects
BIPOLAR disorder, PATIENT participation, AFFECTIVE disorders, PANEL analysis, AGE of onset
Abstract

Introduction Longitudinal study is an essential methodology for understanding disease trajectories, treatment effects, symptom changes, and long-term outcomes of affective disorders. Daily self-charting of mood and other illness-related variables is a commonly recommended intervention. With the widespread acceptance of home computers in the early 2000s, automated tools were developed for patient mood charting, such as ChronoRecord, a software validated by patients with bipolar disorder. The purpose of this study was to summarize the daily mood, sleep, and medication data collected with ChronoRecord, and highlight some of the key research findings. Lessons learned from implementing a computerized tool for patient self-reporting are also discussed. Methods After a brief training session, ChronoRecord software for daily mood charting was installed on a home computer and used by 609 patients with affective disorders. Results The mean age of the patients was 40.3±11.8 years, a mean age of onset was 22±11.2 years, and 71.4% were female. Patients were euthymic for 70.8% of days, 15.1% had mild depression, 6.6% had severe depression, 6.6% had hypomania, and 0.8% had mania. Among all mood groups, 22.4% took 1–2 medications, 37.2% took 3–4 medications, 25.7 took 5–6 medications, 11.6% took 7–8 medications, and 3.1% took >8 medications. Conclusion The daily mood charting tool is a useful tool for increasing patient involvement in their care, providing detailed patient data to the physician, and increasing understanding of the course of illness. Longitudinal data from patient mood charting was helpful in both clinical and research settings. [ABSTRACT FROM AUTHOR]

Published
2023
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34. Internet use by older adults with bipolar disorder: international survey results

Author

Bauer, Rita, Glenn, Tasha, Strejilevich, Sergio, Conell, Jörn, Alda, Martin, Ardau, Raffaella, Baune, Bernhard T., Berk, Michael, Bersudsky, Yuly, Bilderbeck, Amy, Bocchetta, Alberto, Castro, Angela M. Paredes, Cheung, Eric Y. W., Chillotti, Caterina, Choppin, Sabine, Cuomo, Alessandro, Del Zompo, Maria, Dias, Rodrigo, Dodd, Seetal, Duffy, Anne, Etain, Bruno, Fagiolini, Andrea, Fernández Hernandez, Miryam, Garnham, Julie, Geddes, John, Gildebro, Jonas, Gitlin, Michael J., Gonzalez-Pinto, Ana, Goodwin, Guy M., Grof, Paul, Harima, Hirohiko, Hassel, Stefanie, Henry, Chantal, Hidalgo-Mazzei, Diego, Lund, Anne Hvenegaard, Kapur, Vaisnvy, Kunigiri, Girish, Lafer, Beny, Larsen, Erik R., Lewitzka, Ute, Licht, Rasmus W., Misiak, Blazej, Piotrowski, Patryk, Miranda-Scippa, Ângela, Monteith, Scott, Munoz, Rodrigo, Nakanotani, Takako, Nielsen, René E., O’Donovan, Claire, Okamura, Yasushi, Osher, Yamima, Reif, Andreas, Ritter, Philipp, Rybakowski, Janusz K., Sagduyu, Kemal, Sawchuk, Brett, Schwartz, Elon, Slaney, Claire, Sulaiman, Ahmad H., Suominen, Kirsi, Suwalska, Aleksandra, Tam, Peter, Tatebayashi, Yoshitaka, Tondo, Leonardo, Veeh, Julia, Vieta, Eduard, Vinberg, Maj, Viswanath, Biju, Zetin, Mark, Whybrow, Peter C., and Bauer, Michael

Published
2018
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36. Online information seeking by patients with bipolar disorder: results from an international multisite survey

Author

Conell, Jörn, Bauer, Rita, Glenn, Tasha, Alda, Martin, Ardau, Raffaella, Baune, Bernhard T., Berk, Michael, Bersudsky, Yuly, Bilderbeck, Amy, Bocchetta, Alberto, Bossini, Letizia, Paredes Castro, Angela Marianne, Cheung, Eric Yat Wo, Chillotti, Caterina, Choppin, Sabine, Del Zompo, Maria, Dias, Rodrigo, Dodd, Seetal, Duffy, Anne, Etain, Bruno, Fagiolini, Andrea, Garnham, Julie, Geddes, John, Gildebro, Jonas, Gonzalez-Pinto, Ana, Goodwin, Guy M., Grof, Paul, Harima, Hirohiko, Hassel, Stefanie, Henry, Chantal, Hidalgo-Mazzei, Diego, Kapur, Vaisnvy, Kunigiri, Girish, Lafer, Beny, Lam, Chun, Larsen, Erik Roj, Lewitzka, Ute, Licht, Rasmus, Lund, Anne Hvenegaard, Misiak, Blazej, Piotrowski, Patryk, Monteith, Scott, Munoz, Rodrigo, Nakanotani, Takako, Nielsen, René E., O’Donovan, Claire, Okamura, Yasushi, Osher, Yamima, Reif, Andreas, Ritter, Philipp, Rybakowski, Janusz K., Sagduyu, Kemal, Sawchuk, Brett, Schwartz, Elon, Scippa, Ângela Miranda, Slaney, Claire, Sulaiman, Ahmad Hatim, Suominen, Kirsi, Suwalska, Aleksandra, Tam, Peter, Tatebayashi, Yoshitaka, Tondo, Leonardo, Vieta, Eduard, Vinberg, Maj, Viswanath, Biju, Volkert, Julia, Zetin, Mark, Zorrilla, Iñaki, Whybrow, Peter C., and Bauer, Michael

Published
2016
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43. Erratum to: Online information seeking by patients with bipolar disorder: results from an international multisite survey

Author

Conell, Jörn, Bauer, Rita, Glenn, Tasha, Alda, Martin, Ardau, Raffaella, Baune, Bernhard T., Berk, Michael, Bersudsky, Yuly, Bilderbeck, Amy, Bocchetta, Alberto, Bossini, Letizia, Paredes Castro, Angela Marianne, Cheung, Eric Yat Wo, Chillotti, Caterina, Choppin, Sabine, Del Zompo, Maria, Dias, Rodrigo, Dodd, Seetal, Duffy, Anne, Etain, Bruno, Fagiolini, Andrea, Garnham, Julie, Geddes, John, Gildebro, Jonas, Gonzalez-Pinto, Ana, Goodwin, Guy M., Grof, Paul, Harima, Hirohiko, Hassel, Stefanie, Henry, Chantal, Hidalgo-Mazzei, Diego, Kapur, Vaisnvy, Kunigiri, Girish, Lafer, Beny, Lam, Chun, Larsen, Erik Roj, Lewitzka, Ute, Licht, Rasmus W., Lund, Anne Hvenegaard, Misiak, Blazej, Piotrowski, Patryk, Monteith, Scott, Munoz, Rodrigo, Nakanotani, Takako, Nielsen, René E., O’Donovan, Claire, Okamura, Yasushi, Osher, Yamima, Reif, Andreas, Ritter, Philipp, Rybakowski, Janusz K., Sagduyu, Kemal, Sawchuk, Brett, Schwartz, Elon, Scippa, Ângela Miranda, Slaney, Claire, Sulaiman, Ahmad Hatim, Suominen, Kirsi, Suwalska, Aleksandra, Tam, Peter, Tatebayashi, Yoshitaka, Tondo, Leonardo, Vieta, Eduard, Vinberg, Maj, Viswanath, Biju, Volkert, Julia, Zetin, Mark, Zorrilla, Iñaki, Whybrow, Peter C., and Bauer, Michael

Published
2017
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