Search

Your search keyword '"Wichter, Thomas"' showing total 493 results
Start Over Author "Wichter, Thomas"
493 results on '"Wichter, Thomas"'

1. Proposed diagnostic criteria for arrhythmogenic cardiomyopathy: European Task Force consensus report

Author

Corrado, Domenico, Anastasakis, Aris, Basso, Cristina, Bauce, Barbara, Blomström-Lundqvist, Carina, Bucciarelli-Ducci, Chiara, Cipriani, Alberto, De Asmundis, Carlo, Gandjbakhch, Estelle, Jiménez-Jáimez, Juan, Kharlap, Maria, McKenna, William J, Monserrat, Lorenzo, Moon, James, Pantazis, Antonis, Pelliccia, Antonio, Perazzolo Marra, Martina, Pillichou, Kalliopi, Schulz-Menger, Jeanette, Jurcut, Ruxandra, Seferovic, Petar, Sharma, Sanjay, Tfelt-Hansen, Jacob, Thiene, Gaetano, Wichter, Thomas, Wilde, Arthur, and Zorzi, Alessandro

Published
2024
Full Text
View/download PDF

3. Proposed diagnostic criteria for arrhythmogenic cardiomyopathy:European Task Force consensus report

Author

Corrado, Domenico, Anastasakis, Aris, Basso, Cristina, Bauce, Barbara, Blomström-Lundqvist, Carina, Bucciarelli-Ducci, Chiara, Cipriani, Alberto, De Asmundis, Carlo, Gandjbakhch, Estelle, Jiménez-Jáimez, Juan, Kharlap, Maria, McKenna, William J., Monserrat, Lorenzo, Moon, James, Pantazis, Antonis, Pelliccia, Antonio, Perazzolo Marra, Martina, Pillichou, Kalliopi, Schulz-Menger, Jeanette, Jurcut, Ruxandra, Seferovic, Petar, Sharma, Sanjay, Tfelt-Hansen, Jacob, Thiene, Gaetano, Wichter, Thomas, Wilde, Arthur, Zorzi, Alessandro, Corrado, Domenico, Anastasakis, Aris, Basso, Cristina, Bauce, Barbara, Blomström-Lundqvist, Carina, Bucciarelli-Ducci, Chiara, Cipriani, Alberto, De Asmundis, Carlo, Gandjbakhch, Estelle, Jiménez-Jáimez, Juan, Kharlap, Maria, McKenna, William J., Monserrat, Lorenzo, Moon, James, Pantazis, Antonis, Pelliccia, Antonio, Perazzolo Marra, Martina, Pillichou, Kalliopi, Schulz-Menger, Jeanette, Jurcut, Ruxandra, Seferovic, Petar, Sharma, Sanjay, Tfelt-Hansen, Jacob, Thiene, Gaetano, Wichter, Thomas, Wilde, Arthur, and Zorzi, Alessandro

Abstract

Arrhythmogenic cardiomyopathy (ACM) is a heart muscle disease characterized by prominent “non-ischemic” myocardial scarring predisposing to ventricular electrical instability. Diagnostic criteria for the original phenotype, arrhythmogenic right ventricular cardiomyopathy (ARVC), were first proposed in 1994 and revised in 2010 by an international Task Force (TF). A 2019 International Expert report appraised these previous criteria, finding good accuracy for diagnosis of ARVC but a lack of sensitivity for identification of the expanding phenotypic disease spectrum, which includes left-sided variants, i.e., biventricular (ABVC) and arrhythmogenic left ventricular cardiomyopathy (ALVC). The ARVC phenotype together with these left-sided variants are now more appropriately named ACM. The lack of diagnostic criteria for the left ventricular (LV) phenotype has resulted in clinical under-recognition of ACM patients over the 4 decades since the disease discovery. In 2020, the “Padua criteria” were proposed for both right- and left-sided ACM phenotypes. The presently proposed criteria represent a refinement of the 2020 Padua criteria and have been developed by an expert European TF to improve the diagnosis of ACM with upgraded and internationally recognized criteria. The growing recognition of the diagnostic role of CMR has led to the incorporation of myocardial tissue characterization findings for detection of myocardial scar using the late‑gadolinium enhancement (LGE) technique to more fully characterize right, biventricular and left disease variants, whether genetic or acquired (phenocopies), and to exclude other “non-scarring” myocardial disease. The “ring-like’ pattern of myocardial LGE/scar is now a recognized diagnostic hallmark of ALVC. Additional diagnostic criteria regarding LV depolarization and repolarization ECG abnormalities and ventricular arrhythmias of LV origin are also provided. These proposed upgrading of diagnostic criteria represents a working framewor

Published
2024

13. Arrhythmogenic right ventricular cardiomyopathy/dysplasia clinical presentation and diagnostic evaluation: Results from the North American Multidisciplinary Study

Author

Marcus, Frank I., Zareba, Wojciech, Calkins, Hugh, Towbin, Jeffrey A., Basso, Cristina, Bluemke, David A., Estes, N.A. Mark, III, Picard, Michael H., Sanborn, Danita, Thiene, Gaetano, Wichter, Thomas, Cannom, David, Wilber, David J., Scheinman, Melvin, Duff, Henry, Daubert, James, Talajic, Mario, Krahn, Andrew, Sweeney, Michael, Garan, Hasan, Sakaguchi, Scott, Lerman, Bruce B., Kerr, Charles, Kron, Jack, Steinberg, Jonathan S., Sherrill, Duane, Gear, Kathleen, Brown, Mary, Severski, Patricia, Polonsky, Slava, and McNitt, Scott

Published
2009
Full Text
View/download PDF

14. Genome-wide association analysis in dilated cardiomyopathy reveals two new players in systolic heart failure on chromosomes 3p25.1 and 22q11.23

Author

Onderzoek Precision medicine, Circulatory Health, Child Health, Aios en Stafsecr. Cardiologie, Experimentele Afd. Cardiologie 2, Team Medisch, Onderzoek Cardiovasculair Reg. Med., Garnier, Sophie, Harakalova, Magdalena, Weiss, Stefan, Mokry, Michal, Regitz-Zagrosek, Vera, Hengstenberg, Christian, Cappola, Thomas P, Isnard, Richard, Arbustini, Eloisa, Cook, Stuart A, van Setten, Jessica, Calis, Jorg J A, Hakonarson, Hakon, Morley, Michael P, Stark, Klaus, Prasad, Sanjay K, Li, Jin, O'Regan, Declan P, Grasso, Maurizia, Müller-Nurasyid, Martina, Meitinger, Thomas, Empana, Jean-Philippe, Strauch, Konstantin, Waldenberger, Melanie, Marguiles, Kenneth B, Seidman, Christine E, Kararigas, Georgios, Meder, Benjamin, Haas, Jan, Boutouyrie, Pierre, Lacolley, Patrick, Jouven, Xavier, Erdmann, Jeanette, Blankenberg, Stefan, Wichter, Thomas, Ruppert, Volker, Tavazzi, Luigi, Dubourg, Olivier, Roizes, Gérard, Dorent, Richard, de Groote, Pascal, Fauchier, Laurent, Trochu, Jean-Noël, Aupetit, Jean-François, Bilinska, Zofia T, Germain, Marine, Völker, Uwe, Hemerich, Daiane, Raji, Ibticem, Bacq-Daian, Delphine, Proust, Carole, Remior, Paloma, Gomez-Bueno, Manuel, Lehnert, Kristin, Maas, Renee, Olaso, Robert, Saripella, Ganapathi Varma, Felix, Stephan B, McGinn, Steven, Duboscq-Bidot, Laëtitia, van Mil, Alain, Besse, Céline, Fontaine, Vincent, Blanché, Hélène, Ader, Flavie, Keating, Brendan, Curjol, Angélique, Boland, Anne, Komajda, Michel, Cambien, François, Deleuze, Jean-François, Dörr, Marcus, Asselbergs, Folkert W, Villard, Eric, Trégouët, David-Alexandre, Charron, Philippe, Maas, Renee GC, Onderzoek Precision medicine, Circulatory Health, Child Health, Aios en Stafsecr. Cardiologie, Experimentele Afd. Cardiologie 2, Team Medisch, Onderzoek Cardiovasculair Reg. Med., Garnier, Sophie, Harakalova, Magdalena, Weiss, Stefan, Mokry, Michal, Regitz-Zagrosek, Vera, Hengstenberg, Christian, Cappola, Thomas P, Isnard, Richard, Arbustini, Eloisa, Cook, Stuart A, van Setten, Jessica, Calis, Jorg J A, Hakonarson, Hakon, Morley, Michael P, Stark, Klaus, Prasad, Sanjay K, Li, Jin, O'Regan, Declan P, Grasso, Maurizia, Müller-Nurasyid, Martina, Meitinger, Thomas, Empana, Jean-Philippe, Strauch, Konstantin, Waldenberger, Melanie, Marguiles, Kenneth B, Seidman, Christine E, Kararigas, Georgios, Meder, Benjamin, Haas, Jan, Boutouyrie, Pierre, Lacolley, Patrick, Jouven, Xavier, Erdmann, Jeanette, Blankenberg, Stefan, Wichter, Thomas, Ruppert, Volker, Tavazzi, Luigi, Dubourg, Olivier, Roizes, Gérard, Dorent, Richard, de Groote, Pascal, Fauchier, Laurent, Trochu, Jean-Noël, Aupetit, Jean-François, Bilinska, Zofia T, Germain, Marine, Völker, Uwe, Hemerich, Daiane, Raji, Ibticem, Bacq-Daian, Delphine, Proust, Carole, Remior, Paloma, Gomez-Bueno, Manuel, Lehnert, Kristin, Maas, Renee, Olaso, Robert, Saripella, Ganapathi Varma, Felix, Stephan B, McGinn, Steven, Duboscq-Bidot, Laëtitia, van Mil, Alain, Besse, Céline, Fontaine, Vincent, Blanché, Hélène, Ader, Flavie, Keating, Brendan, Curjol, Angélique, Boland, Anne, Komajda, Michel, Cambien, François, Deleuze, Jean-François, Dörr, Marcus, Asselbergs, Folkert W, Villard, Eric, Trégouët, David-Alexandre, Charron, Philippe, and Maas, Renee GC

Published
2021

19. Genome-wide association analysis in dilated cardiomyopathy reveals two new players in systolic heart failure on chromosomes 3p25.1 and 22q11.23

Author

Garnier, Sophie, primary, Harakalova, Magdalena, additional, Weiss, Stefan, additional, Mokry, Michal, additional, Regitz-Zagrosek, Vera, additional, Hengstenberg, Christian, additional, Cappola, Thomas P, additional, Isnard, Richard, additional, Arbustini, Eloisa, additional, Cook, Stuart A, additional, van Setten, Jessica, additional, Calis, Jorg J A, additional, Hakonarson, Hakon, additional, Morley, Michael P, additional, Stark, Klaus, additional, Prasad, Sanjay K, additional, Li, Jin, additional, O'Regan, Declan P, additional, Grasso, Maurizia, additional, Müller-Nurasyid, Martina, additional, Meitinger, Thomas, additional, Empana, Jean-Philippe, additional, Strauch, Konstantin, additional, Waldenberger, Melanie, additional, Marguiles, Kenneth B, additional, Seidman, Christine E, additional, Kararigas, Georgios, additional, Meder, Benjamin, additional, Haas, Jan, additional, Boutouyrie, Pierre, additional, Lacolley, Patrick, additional, Jouven, Xavier, additional, Erdmann, Jeanette, additional, Blankenberg, Stefan, additional, Wichter, Thomas, additional, Ruppert, Volker, additional, Tavazzi, Luigi, additional, Dubourg, Olivier, additional, Roizes, Gérard, additional, Dorent, Richard, additional, de Groote, Pascal, additional, Fauchier, Laurent, additional, Trochu, Jean-Noël, additional, Aupetit, Jean-François, additional, Bilinska, Zofia T, additional, Germain, Marine, additional, Völker, Uwe, additional, Hemerich, Daiane, additional, Raji, Ibticem, additional, Bacq-Daian, Delphine, additional, Proust, Carole, additional, Remior, Paloma, additional, Gomez-Bueno, Manuel, additional, Lehnert, Kristin, additional, Maas, Renee, additional, Olaso, Robert, additional, Saripella, Ganapathi Varma, additional, Felix, Stephan B, additional, McGinn, Steven, additional, Duboscq-Bidot, Laëtitia, additional, van Mil, Alain, additional, Besse, Céline, additional, Fontaine, Vincent, additional, Blanché, Hélène, additional, Ader, Flavie, additional, Keating, Brendan, additional, Curjol, Angélique, additional, Boland, Anne, additional, Komajda, Michel, additional, Cambien, François, additional, Deleuze, Jean-François, additional, Dörr, Marcus, additional, Asselbergs, Folkert W, additional, Villard, Eric, additional, Trégouët, David-Alexandre, additional, and Charron, Philippe, additional

Published
2021
Full Text
View/download PDF

23. A novel dominant mutation in plakoglobin causes arrhythmogenic right ventricular cardiomyopathy

Author

Asimaki, Angeliki, Syrris, Petros, Wichter, Thomas, Matthias, Paul, Saffitz, Jeffrey E., and McKenna, William J.

Subjects
Mutation (Biology) -- Research, Cardiomyopathy -- Research, Heart diseases -- Research, Skin diseases -- Research, Skin diseases -- Genetic aspects, Biological sciences
Abstract

A dominant mutation in the gene encoding plakoglobin in a German family with arrhythmogenic right ventricular cardiomyopathy (ARVC) but no cutaneous abnormalities is reported.

Published
2007

24. Mid-regional proatrial natriuretic peptide for predicting prognosis in hypertrophic cardiomyopathy

Author

Begue, Celine, Mörner, Stellan, Brito, Dulce, Hengstenberg, Christian, Cleland, John G. F., Arbustini, Eloisa, Galve, Enrique, Wichter, Thomas, Richter, Anette, Golmard, Jean-Louis, Bernard, Maguy, Dubourg, Olivier, Komajda, Michel, Charron, Philippe, Isnard, Richard, Begue, Celine, Mörner, Stellan, Brito, Dulce, Hengstenberg, Christian, Cleland, John G. F., Arbustini, Eloisa, Galve, Enrique, Wichter, Thomas, Richter, Anette, Golmard, Jean-Louis, Bernard, Maguy, Dubourg, Olivier, Komajda, Michel, Charron, Philippe, and Isnard, Richard

Abstract

Objectives N-terminal probrain natriuretic peptide (NT-proBNP) predicts mortality and the development of heart failure in hypertrophic cardiomyopathy (HCM). Mid-regional proatrial natriuretic peptide (MR-proANP) is a stable by-product of production of atrial natriuretic peptide. We sought to compare the prognostic value of MR-proANP and NT-proBNP in HCM. Methods We prospectively enrolled a cohort of patients with HCM from different European centres and followed them. All patients had clinical, ECG and echocardiographic evaluation and measurement of MR-proANP and NT-proBNP at inclusion. Results Of 357 patients enrolled, the median age was 52 (IQR: 36-65) years. MR-proANP and NT-proBNP were both independently associated with age, weight, New York Heart Association (NYHA) class, left ventricular ejection fraction (LVEF), wall thickness and left atrial dimension. During a median follow-up of 23 months, 32 patients had a primary end point defined as death (n=6), heart transplantation (n=8), left ventricular assist device implantation (n=1) or heart failure hospitalisation (n=17). Both NT-proBNP and MR-proANP (p<10(-4)) were strongly associated with the primary endpoint, and the areas under the receiver operating characteristic (ROC) curves for both peptides were not significantly different. However, in a multiple stepwise regression analysis, the best model for predicting outcome was NYHA 1-2 vs 3-4 (HR=0.35, 95% CI 0.16 to 0.77, p<0.01), LVEF (HR=0.96, 95% CI 0.94 to 0.98, p=0.0005) and MR-proANP (HR=3.77, 95% CI 2.01 to 7.08, p<0.0001). Conclusions MR-proANP emerges as a valuable biomarker for the prediction of death and heart failure related events in patients with HCM.

Published
2020
Full Text
View/download PDF

25. Diagnosis of arrhythmogenic cardiomyopathy: The Padua criteria

Author

Corrado, Domenico, Perazzolo Marra, Martina, Zorzi, Alessandro, Beffagna, Giorgia, Cipriani, Alberto, De Lazzari, Manuel, Migliore, Federico, Pilichou, Kalliopi, Rampazzo, Alessandra, Rigato, Ilaria, Rizzo, Stefania, Thiene, Gaetano, Anastasakis, Aris, Asimaki, Angeliki, Bucciarelli-Ducci, Chiara, Haugaa, Kristine H, Marchlinski, Francis E, Mazzanti, Andrea, McKenna, William J, Pantazis, Antonis, Pelliccia, Antonio, Schmied, Christian, Sharma, Sanjay, Wichter, Thomas, Bauce, Barbara, Basso, Cristina, Corrado, Domenico, Perazzolo Marra, Martina, Zorzi, Alessandro, Beffagna, Giorgia, Cipriani, Alberto, De Lazzari, Manuel, Migliore, Federico, Pilichou, Kalliopi, Rampazzo, Alessandra, Rigato, Ilaria, Rizzo, Stefania, Thiene, Gaetano, Anastasakis, Aris, Asimaki, Angeliki, Bucciarelli-Ducci, Chiara, Haugaa, Kristine H, Marchlinski, Francis E, Mazzanti, Andrea, McKenna, William J, Pantazis, Antonis, Pelliccia, Antonio, Schmied, Christian, Sharma, Sanjay, Wichter, Thomas, Bauce, Barbara, and Basso, Cristina

Abstract

The original designation of "Arrhythmogenic right ventricular (dysplasia/) cardiomyopathy"(ARVC) was used by the scientists who first discovered the disease, in the pre-genetic and pre-cardiac magnetic resonance era, to describe a new heart muscle disease predominantly affecting the right ventricle, whose cardinal clinical manifestation was the occurrence of malignant ventricular arrhythmias. Subsequently, autopsy investigations, genotype-phenotype correlations studies and the increasing use of contrast-enhancement cardiac magnetic resonance showed that the fibro-fatty replacement of the myocardium represents the distinctive phenotypic feature of the disease that affects the myocardium of both ventricles, with left ventricular involvement which may parallel or exceed the severity of right ventricular involvement. This has led to the new designation of "Arrhythmogenic Cardiomyopathy" (ACM), that represents the evolution of the original term of ARVC. The present International Expert Consensus document proposes an upgrade of the criteria for diagnosis of the entire spectrum of the phenotypic variants of ACM. The proposed "Padua criteria" derive from the diagnostic approach to ACM, which has been developed over 30 years by the multidisciplinary team of basic researchers and clinical cardiologists of the Medical School of the University of Padua. The Padua criteria are a working framework to improve the diagnosis of ACM by introducing new diagnostic criteria regarding tissue characterization findings by contrast-enhanced cardiac magnetic resonance, depolarization/repolarization ECG abnormalities and ventricular arrhythmia features for diagnosis of the left ventricular phenotype. The proposed diagnostic criteria need to be further validated by future clinical studies in large cohorts of patients.

Published
2020

29. Mutant desmocollin-2 causes arrhythmogenic right ventricular cardiomyopathy

Author

Heuser, Arnd, Plovie, Eva R., Ellinor, Patrick T., Grossmann, Katja S., Shin, Jordan T., Wichter, Thomas, Basson, Craig T., Sasse-Klaassen, Sabine, Thierfelder, Ludwig, MacRae, Calum A., and Gerull, Brenda

Subjects
Cardiomyopathy -- Genetic aspects, Heart diseases -- Genetic aspects, Introns -- Research, Gene mutations -- Research, Desmosomes -- Structure, Desmosomes -- Research, Biological sciences
Abstract

Many unrelated patients with the disorder for mutation in human desmosomal cadherin desmocollin-2 (DSC2) are investigated. The results have identified DSC2 mutations as a cause of arrhythmogenic right ventricular cardiomyopathy (ARVC) in humans and have shown that physiologic levels of DSC2 are crucial for normal cardiac desmosome formation, early cardiac morphogenesis and cardiac function.

Published
2006

36. Klinik und Therapie des Brugada-Syndroms

Author

Eckardt, Lars, Rolf, Sascha, Mönnig, Gerold, Bruns, Hans-Jürgen, Schulze-Bahr, Eric, Milberg, Peter, Kirchhof, Paulus, Wichter, Thomas, Borggrefe, M., Breithardt, Günter, and Haverkamp, Wilhelm

Published
2002
Full Text
View/download PDF

42. Evidence for FHL1 as a novel disease gene for isolated hypertrophic cardiomyopathy

Author

Friedrich, Felix W., Wilding, Brendan R., Reischmann, Silke, Crocini, Claudia, Lang, Patrick, Charron, Philippe, Müller, Oliver J., McGrath, Meagan J., Vollert, Ingra, Hansen, Arne, Linke, Wolfgang A., Hengstenberg, Christian, Bonne, Gisèle, Morner, Stellan, Wichter, Thomas, Madeira, Hugo, Arbustini, Eloisa, Eschenhagen, Thomas, Mitchell, Christina A., Isnard, Richard, and Carrier, Lucie

Published
2012
Full Text
View/download PDF

44. Diagnosis of arrhythmogenic cardiomyopathy: The Padua criteria

Author

Corrado, Domenico, primary, Perazzolo Marra, Martina, additional, Zorzi, Alessandro, additional, Beffagna, Giorgia, additional, Cipriani, Alberto, additional, Lazzari, Manuel De, additional, Migliore, Federico, additional, Pilichou, Kalliopi, additional, Rampazzo, Alessandra, additional, Rigato, Ilaria, additional, Rizzo, Stefania, additional, Thiene, Gaetano, additional, Anastasakis, Aris, additional, Asimaki, Angeliki, additional, Bucciarelli-Ducci, Chiara, additional, Haugaa, Kristine H., additional, Marchlinski, Francis E., additional, Mazzanti, Andrea, additional, McKenna, William J., additional, Pantazis, Antonis, additional, Pelliccia, Antonio, additional, Schmied, Christian, additional, Sharma, Sanjay, additional, Wichter, Thomas, additional, Bauce, Barbara, additional, and Basso, Cristina, additional

Published
2020
Full Text
View/download PDF

46. Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: Proposed Modification of the Task Force Criteria

Author

Marcus, Frank I., McKenna, William J., Sherrill, Duane, Basso, Cristina, Bauce, Barbara, Bluemke, David A., Calkins, Hugh, Corrado, Domenico, Cox, Moniek G.P.J., Daubert, James P., Fontaine, Guy, Gear, Kathleen, Hauer, Richard, Nava, Andrea, Picard, Michael H., Protonotarios, Nikos, Saffitz, Jeffrey E., Sanborn, Danita M., Steinberg, Jonathan S., Tandri, Harikrishna, Thiene, Gaetano, Towbin, Jeffrey A., Tsatsopoulou, Adalena, Wichter, Thomas, and Zareba, Wojciech

Published
2010
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results