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127 results on '"Wiebe, Sheldon"'

3. MRI overestimates articular cartilage thickness and volume compared to synchrotron radiation phase-contrast imaging

Author

Bairagi, Suranjan, primary, Abdollahifar, Mohammad-Amin, additional, Atake, Oghenevwogaga J., additional, Dust, William, additional, Wiebe, Sheldon, additional, Belev, George, additional, Chapman, L. Dean, additional, Webb, M. Adam, additional, Zhu, Ning, additional, Cooper, David M. L., additional, and Eames, B. Frank, additional

Published
2023
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6. CTA, MRA, US and Nuclear Medicine as noninvasive imaging modalities for renal artery stenosis in adults: A scoping review

Author

Gurinder, Kirkpatrick, Ian, Goubran, Ashraf, and Wiebe, Sheldon

Subjects
Investigative Techniques, Diagnosis, Medicine and Health Sciences, Medical Specialties, Radiology, Analytical, Diagnostic and Therapeutic Techniques and Equipment
Abstract

In this scoping review, we will be working to map or chart the existing literature in relevance to noninvasive imaging modalities for diagnosing renal artery stenosis. Being a scoping review, no new data will be synthesized or created from the secondary data.

Published
2022
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8. Inter‐ and intraobserver agreement for CT measurement of mandibular and medial retropharyngeal lymph nodes is excellent in dogs with histologically confirmed oral melanoma

Author

Cotter, Brad, primary, Zwicker, Lesley A., additional, Waldner, Cheryl, additional, Randall, Elissa, additional, Gagnon, Jerome, additional, Wiebe, Sheldon, additional, Cohen, Eli B., additional, Hespel, Adrien‐Maxence, additional, de Swarte, Marie, additional, and Mayer, Monique N., additional

Published
2021
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15. Two children with extra-nodalMycobacterium aviumcomplex infection

Author

Markland, Ali, primary, Tan, Ben, additional, Adamko, Darryl, additional, Diener, Tania, additional, Levett, Paul N, additional, Wiebe, Sheldon, additional, Wang, Hui, additional, Podberezin, Mark, additional, Saczek, Krysztof, additional, Milbrandt, Kris, additional, Essalah, Abdulhafid, additional, Quan, William, additional, and Deneer, Harry, additional

Published
2020
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16. Inter‐ and intraobserver agreement for CT measurement of mandibular and medial retropharyngeal lymph nodes is excellent in dogs with histologically confirmed oral melanoma.

Author

Cotter, Brad, Zwicker, Lesley A., Waldner, Cheryl, Randall, Elissa, Gagnon, Jerome, Wiebe, Sheldon, Cohen, Eli B., Hespel, Adrien‐Maxence, de Swarte, Marie, and Mayer, Monique N.

Abstract

Mandibular and medial retropharyngeal lymph nodes are routinely evaluated with CT when staging dogs with oral melanomas. While size alone is considered inadequate for detecting nodal metastasis, it is critical in evaluating treatment response, as clinical decisions are based on changes in size. It is common for different radiologists to measure the size of pre‐ and posttreatment lymph nodes in the same patient. The objective of this retrospective, observer agreement study was to evaluate the inter‐ and intraobserver agreement in measuring canine mandibular and medial retropharyngeal lymph nodes by a diverse population of veterinary radiologists and trainees. Fourteen dogs with documented oral melanoma and head CT studies identified from records of a single institution were included in this study. North American veterinary radiologists and trainees were recruited to measure the mandibular and medial retropharyngeal lymph nodes; in triplicate. Prior to performing the study measurements, participants completed a training tool demonstrating the lymph node measurements. Overall, interobserver intraclass correlation coefficient (ICC) was 0.961 (95% confidence interval [CI]: 0.946, 0.972) and intraobserver ICC was 0.977 (95% CI: 0.968, 0.983), indicating excellent agreement (ICC > 0.9 considered excellent). Similar findings were noted following sub‐analysis for most variables (experience, size, laterality, axis of measurement). These results suggest that follow‐up measurement of the long and short axis of the mandibular lymph nodes and short axis of the medial retropharyngeal lymph nodes in the transverse plane, performed by different veterinary radiologists using the same method of measure, should have minimal impact on clinical decision making. [ABSTRACT FROM AUTHOR]

Published
2022
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20. Two children with extra-nodal Mycobacterium avium complex infection.

Author

Markland, Ali, Tan, Ben, Adamko, Darryl, Diener, Tania, Levett, Paul N, Wiebe, Sheldon, Wang, Hui, Podberezin, Mark, Saczek, Krysztof, Milbrandt, Kris, Essalah, Abdulhafid, Quan, William, and Deneer, Harry

Subjects
MYCOBACTERIAL disease diagnosis, URINARY tract infection diagnosis, URINARY tract infections, MYCOBACTERIUM avium, RESPIRATORY infections, BATHS, MYCOBACTERIAL diseases, CHILDREN
Abstract

Mycobacterium avium complex (MAC) is usually considered an opportunistic organism, which infects immunocompromised children or those with structural airway abnormalities. We present two cases of MAC infection affecting immune competent children, likely from hot tubs with primary involvement of pulmonary and urinary systems. These cases highlight the importance of asking about hot tub use in immune competent children with suspected or confirmed MAC infections. [ABSTRACT FROM AUTHOR]

Published
2021
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21. Integrated genome and transcriptome sequencing identifies a noncoding mutation in the genome replication factor DONSON as the cause of microcephaly-micromelia syndrome

Author

Evrony, Gilad D., primary, Cordero, Dwight R., additional, Shen, Jun, additional, Partlow, Jennifer N., additional, Yu, Timothy W., additional, Rodin, Rachel E., additional, Hill, R. Sean, additional, Coulter, Michael E., additional, Lam, Anh-Thu N., additional, Jayaraman, Divya, additional, Gerrelli, Dianne, additional, Diaz, Diana G., additional, Santos, Chloe, additional, Morrison, Victoria, additional, Galli, Antonella, additional, Tschulena, Ulrich, additional, Wiemann, Stefan, additional, Martel, M. Jocelyne, additional, Spooner, Betty, additional, Ryu, Steven C., additional, Elhosary, Princess C., additional, Richardson, Jillian M., additional, Tierney, Danielle, additional, Robinson, Christopher A., additional, Chibbar, Rajni, additional, Diudea, Dana, additional, Folkerth, Rebecca, additional, Wiebe, Sheldon, additional, Barkovich, A. James, additional, Mochida, Ganeshwaran H., additional, Irvine, James, additional, Lemire, Edmond G., additional, Blakley, Patricia, additional, and Walsh, Christopher A., additional

Published
2017
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22. Two children with extra-nodal Mycobacterium aviumcomplex infection.

Author

Markland, Ali, Tan, Ben, Adamko, Darryl, Diener, Tania, Levett, Paul N, Wiebe, Sheldon, Wang, Hui, Podberezin, Mark, Saczek, Krysztof, Milbrandt, Kris, Essalah, Abdulhafid, Quan, William, and Deneer, Harry

Abstract

Mycobacterium aviumcomplex (MAC) is usually considered an opportunistic organism, which infects immunocompromised children or those with structural airway abnormalities. We present two cases of MAC infection affecting immune competent children, likely from hot tubs with primary involvement of pulmonary and urinary systems. These cases highlight the importance of asking about hot tub use in immune competent children with suspected or confirmed MAC infections.

Published
2021
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25. Biomedical Imaging Using Synchrotron Radiation: Experience at the Biomedical Imaging and Therapy (BMIT) Facility at the Canadian Light Source

Author

Wiebe, Sheldon, primary, Wysokinski, Tomasz W., additional, Belev, George, additional, Miller, Denise, additional, Webb, Adam, additional, Zhu, Ning, additional, Cooper, David, additional, Izadifar, Zohreh, additional, Panahifar, Arash, additional, Samadi, Nazanin, additional, Martinson, Mercedes, additional, Ford, Nancy L., additional, Deman, Pierre, additional, Luan, Xiaojie, additional, Ianowski, Juan P., additional, Chen, Daniel, additional, and Chapman, Dean, additional

Published
2015
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28. Integrated genome and transcriptome sequencing identifies a noncoding mutation in the genome replication factor DONSONas the cause of microcephaly-micromelia syndrome

Author

Evrony, Gilad D., Cordero, Dwight R., Shen, Jun, Partlow, Jennifer N., Yu, Timothy W., Rodin, Rachel E., Hill, R. Sean, Coulter, Michael E., Lam, Anh-Thu N., Jayaraman, Divya, Gerrelli, Dianne, Diaz, Diana G., Santos, Chloe, Morrison, Victoria, Galli, Antonella, Tschulena, Ulrich, Wiemann, Stefan, Martel, M. Jocelyne, Spooner, Betty, Ryu, Steven C., Elhosary, Princess C., Richardson, Jillian M., Tierney, Danielle, Robinson, Christopher A., Chibbar, Rajni, Diudea, Dana, Folkerth, Rebecca, Wiebe, Sheldon, Barkovich, A. James, Mochida, Ganeshwaran H., Irvine, James, Lemire, Edmond G., Blakley, Patricia, and Walsh, Christopher A.

Abstract

While next-generation sequencing has accelerated the discovery of human disease genes, progress has been largely limited to the “low hanging fruit” of mutations with obvious exonic coding or canonical splice site impact. In contrast, the lack of high-throughput, unbiased approaches for functional assessment of most noncoding variants has bottlenecked gene discovery. We report the integration of transcriptome sequencing (RNA-seq), which surveys all mRNAs to reveal functional impacts of variants at the transcription level, into the gene discovery framework for a unique human disease, microcephaly-micromelia syndrome (MMS). MMS is an autosomal recessive condition described thus far in only a single First Nations population and causes intrauterine growth restriction, severe microcephaly, craniofacial anomalies, skeletal dysplasia, and neonatal lethality. Linkage analysis of affected families, including a very large pedigree, identified a single locus on Chromosome 21 linked to the disease (LOD > 9). Comprehensive genome sequencing did not reveal any pathogenic coding or canonical splicing mutations within the linkage region but identified several nonconserved noncoding variants. RNA-seq analysis detected aberrant splicing in DONSONdue to one of these noncoding variants, showing a causative role for DONSONdisruption in MMS. We show that DONSONis expressed in progenitor cells of embryonic human brain and other proliferating tissues, is co-expressed with components of the DNA replication machinery, and that Donsonis essential for early embryonic development in mice as well, suggesting an essential conserved role for DONSON in the cell cycle. Our results demonstrate the utility of integrating transcriptomics into the study of human genetic disease when DNA sequencing alone is not sufficient to reveal the underlying pathogenic mutation.

Published
2017
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34. Indirect magnetic resonance lymphography of the head and neck of dogs using Gadofluorine M and a conventional gadolinium contrast agent: A pilot study.

Author

Mayer, Monique N., Kraft, Susan L., Bucy, Daniel S., Waldner, Cheryl L., Elliot, Kirsten M., and Wiebe, Sheldon

Subjects
LYMPH node diseases, DIAGNOSIS of dog diseases, MAGNETIC resonance imaging, LYMPHANGIOGRAPHY, CANCER in dogs, DIAGNOSIS
Abstract

The article focuses on a pilot study that aims at evaluating lymph node enhancement in the head and neck of dogs with an indirect magnetic resonance (MR) lymphography. It describes the methodology of the study in which MR imaging was conducted on five dogs using gadoversetamide and Gadofluorine M contrast agents. It reveals the efficiency of indirect MR lymphography for diagnosing metastatic lymph nodes in dogs with cancer.

Published
2012

35. Answer to Case of the Month #110 Magnetic Resonance Imaging and Spectroscopy in Leigh Disease.

Author

Tynan, Jennifer R., Wiebe, Sheldon, Robinson, Christopher, and Harder, Sheri

Subjects
*FAILURE to thrive syndrome, *MAGNETIC resonance imaging, *DIAGNOSTIC imaging, *GROWTH disorders, *INFANT diseases, *EYE movement disorders, *NYSTAGMUS
Abstract

The article cites a case of a 5-month-old girl who was diagnosed with subacute necrotizing encephalomyelopathy or Leigh disease. She was presented with failure to thrive, developmental regression, visual inattention, and nystagmus. The patient had transient episodes of stiffening of the arms and legs, and arching of the back. Magnetic resonance imaging and magnetic resonance spectroscopy were performed.

Published
2006

37. Case of the Month #110.

Author

Tynan, Jennifer R., Wiebe, Sheldon, Robinson, Christopher, and Harder, Sheri

Subjects
*MEDICAL screening, *DIAGNOSIS, *CHILD development deviations, *FAILURE to thrive syndrome, *EYE movement disorders, *NYSTAGMUS
Abstract

The article discusses the medical examination of an infant patient with failure to thrive, developmental regression, visual inattention, and nystagmus. According to the study, the infant had transient episodes of stiffening of her arms and legs and arching of her back, wherein none of these symptoms were noted until she was three months of age. It has showed that the infant had been born at term by spontaneous vaginal delivery following an uncomplicated pregnancy.

Published
2006

38. Answer to Case of the Month #102 Ortner's Syndrome (Cardiovocal Syndrome).

Author

Wiebe, Sheldon, Shi-Joon Yoo, and Shroff, Manohar

Subjects
*LARYNGEAL nerves, *PARALYSIS, *CARDIOVASCULAR diseases, *HISTOPATHOLOGY, *DIAGNOSIS, *CLINICAL medicine
Abstract

Discusses the case of a 15-year-old girl presented with Ortner's syndrome, a left recurrent laryngeal nerve palsy associated with cardiovascular disease. History of the patient's medical condition; Clinical investigations and diagnosis; Management of the patient's case.

Published
2005

39. Case of the Month # 102.

Author

Wiebe, Sheldon, Shi-Joon Yoo, and Shroff, Manohar

Subjects
*PULMONARY hypertension, *MEDICAL screening, *MEDICAL radiology, *CLINICAL medicine, *PATHOLOGY, *DIAGNOSIS
Abstract

Describes the case of a 15-year-old girl presented with idiopathic pulmonary hypertension. History of the patient's medical condition; Medical examinations undergone; Diagnosis and treatment options for the condition.

Published
2005

40. Canadian Association of Radiologists Recommendations for the Safe Use of MRI During Pregnancy.

Author

Jabehdar Maralani, Pejman, Kapadia, Anish, Liu, Grace, Moretti, Felipe, Ghandehari, Hournaz, Clarke, Sharon E., Wiebe, Sheldon, Garel, Juliette, Ertl-Wagner, Birgit, Hurrell, Casey, and Schieda, Nicola

Subjects
*MAGNETIC resonance imaging, *CONTRAST media, *PREGNANCY
Abstract

The use of magnetic resonance imaging (MRI) during pregnancy is associated with concerns among patients and health professionals with regards to fetal safety. In this work, the Canadian Association of Radiologists (CAR) Working Group on MRI in Pregnancy presents recommendations for the use of MRI in pregnancy, derived from literature review as well as expert panel opinions and discussions. The working group, which consists of academic subspecialty radiologists and obstetrician-gynaecologists, aimed to provide updated, evidence-based recommendations addressing safety domains related to energy deposition, acoustic noise, and gadolinium-based contrast agent use based on magnetic field strength (1.5T and 3T) and trimester scanned, in addition to the effects of sedative use and occupational exposure. [ABSTRACT FROM AUTHOR]

Published
2022
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41. Realistic Synthetic Data Generation: The ATEN Framework

Author

McLachlan, Scott, Dube, Kudakwashe, Gallagher, Thomas, Simmonds, Jennifer A., Fenton, Norman, Barbosa, Simone Diniz Junqueira, Editorial Board Member, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Kotenko, Igor, Editorial Board Member, Yuan, Junsong, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Cliquet Jr., Alberto, editor, Wiebe, Sheldon, editor, Anderson, Paul, editor, Saggio, Giovanni, editor, Zwiggelaar, Reyer, editor, Gamboa, Hugo, editor, Fred, Ana, editor, and Bermúdez i Badia, Sergi, editor

Published
2019
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42. Detecting MRSA Infections by Fusing Structured and Unstructured Electronic Health Record Data

Author

Hartvigsen, Thomas, Sen, Cansu, Rundensteiner, Elke A., Barbosa, Simone Diniz Junqueira, Editorial Board Member, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Kotenko, Igor, Editorial Board Member, Yuan, Junsong, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Cliquet Jr., Alberto, editor, Wiebe, Sheldon, editor, Anderson, Paul, editor, Saggio, Giovanni, editor, Zwiggelaar, Reyer, editor, Gamboa, Hugo, editor, Fred, Ana, editor, and Bermúdez i Badia, Sergi, editor

Published
2019
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43. Multi-layered Learning for Information Extraction from Adverse Drug Event Narratives

Author

Wunnava, Susmitha, Qin, Xiao, Kakar, Tabassum, Tlachac, M. L., Kong, Xiangnan, Rundensteiner, Elke A., Sahoo, Sanjay K., De, Suranjan, Barbosa, Simone Diniz Junqueira, Editorial Board Member, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Kotenko, Igor, Editorial Board Member, Yuan, Junsong, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Cliquet Jr., Alberto, editor, Wiebe, Sheldon, editor, Anderson, Paul, editor, Saggio, Giovanni, editor, Zwiggelaar, Reyer, editor, Gamboa, Hugo, editor, Fred, Ana, editor, and Bermúdez i Badia, Sergi, editor

Published
2019
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44. Application of Sample Entropy of Pulse Waves in Identifying Characteristic Physiological Patterns of Parkinson’s Disease Sufferers

Author

Oyama-Higa, Mayumi, Niwa, Tokihiko, Ou, Fumitake, Kawanabe, Yoshifumi, Barbosa, Simone Diniz Junqueira, Editorial Board Member, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Kotenko, Igor, Editorial Board Member, Yuan, Junsong, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Cliquet Jr., Alberto, editor, Wiebe, Sheldon, editor, Anderson, Paul, editor, Saggio, Giovanni, editor, Zwiggelaar, Reyer, editor, Gamboa, Hugo, editor, Fred, Ana, editor, and Bermúdez i Badia, Sergi, editor

Published
2019
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45. META-GLARE’s Supports to Agent Coordination

Author

Anselma, Luca, Bottrighi, Alessio, Piovesan, Luca, Terenziani, Paolo, Barbosa, Simone Diniz Junqueira, Editorial Board Member, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Kotenko, Igor, Editorial Board Member, Yuan, Junsong, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Cliquet Jr., Alberto, editor, Wiebe, Sheldon, editor, Anderson, Paul, editor, Saggio, Giovanni, editor, Zwiggelaar, Reyer, editor, Gamboa, Hugo, editor, Fred, Ana, editor, and Bermúdez i Badia, Sergi, editor

Published
2019
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46. Application of a Rule-Based Classifier to Data Regarding Radiation Toxicity in Prostate Cancer Treatment

Author

Domínguez-Olmedo, Juan L., Mata, Jacinto, Pachón, Victoria, Lopez Guerra, Jose L., Barbosa, Simone Diniz Junqueira, Editorial Board Member, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Kotenko, Igor, Editorial Board Member, Yuan, Junsong, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Cliquet Jr., Alberto, editor, Wiebe, Sheldon, editor, Anderson, Paul, editor, Saggio, Giovanni, editor, Zwiggelaar, Reyer, editor, Gamboa, Hugo, editor, Fred, Ana, editor, and Bermúdez i Badia, Sergi, editor

Published
2019
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47. A Multiagent-Based Model for Epidemic Disease Monitoring in DR Congo

Author

Tshilenge Mfumu, Jean-Claude, Mercier, Annabelle, Occello, Michel, Verdier, Christine, Barbosa, Simone Diniz Junqueira, Editorial Board Member, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Kotenko, Igor, Editorial Board Member, Yuan, Junsong, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Cliquet Jr., Alberto, editor, Wiebe, Sheldon, editor, Anderson, Paul, editor, Saggio, Giovanni, editor, Zwiggelaar, Reyer, editor, Gamboa, Hugo, editor, Fred, Ana, editor, and Bermúdez i Badia, Sergi, editor

Published
2019
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48. Predictive Modeling of Emerging Antibiotic Resistance Trends

Author

Tlachac, M. L., Rundensteiner, Elke A., Troppy, T. Scott, Beaulac, Kirthana, Doron, Shira, Barton, Kerri, Barbosa, Simone Diniz Junqueira, Editorial Board Member, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Kotenko, Igor, Editorial Board Member, Yuan, Junsong, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Cliquet Jr., Alberto, editor, Wiebe, Sheldon, editor, Anderson, Paul, editor, Saggio, Giovanni, editor, Zwiggelaar, Reyer, editor, Gamboa, Hugo, editor, Fred, Ana, editor, and Bermúdez i Badia, Sergi, editor

Published
2019
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49. Exploring the Value of Electronic Health Records from Multiple Datasets

Author

Fajarda, Olga, Trifan, Alina, Van Speybroeck, Michel, Rijnbeek, Peter R., Oliveira, José Luís, Barbosa, Simone Diniz Junqueira, Editorial Board Member, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Kotenko, Igor, Editorial Board Member, Yuan, Junsong, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Cliquet Jr., Alberto, editor, Wiebe, Sheldon, editor, Anderson, Paul, editor, Saggio, Giovanni, editor, Zwiggelaar, Reyer, editor, Gamboa, Hugo, editor, Fred, Ana, editor, and Bermúdez i Badia, Sergi, editor

Published
2019
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50. Considerations on the Usability of SClínico

Author

Pavão, João, Bastardo, Rute, Torres Pereira, Luís, Oliveira, Paula, Costa, Victor, Martins, Ana Isabel, Queirós, Alexandra, Rocha, Nelson Pacheco, Barbosa, Simone Diniz Junqueira, Editorial Board Member, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Kotenko, Igor, Editorial Board Member, Yuan, Junsong, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Cliquet Jr., Alberto, editor, Wiebe, Sheldon, editor, Anderson, Paul, editor, Saggio, Giovanni, editor, Zwiggelaar, Reyer, editor, Gamboa, Hugo, editor, Fred, Ana, editor, and Bermúdez i Badia, Sergi, editor

Published
2019
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