Search

Your search keyword '"Wilhelmus, Suzanne"' showing total 21 results
Start Over Author "Wilhelmus, Suzanne"
21 results on '"Wilhelmus, Suzanne"'

3. Increased microchimerism in peripheral blood of women with systemic lupus erythematosus: relation with pregnancy

Author

Bos, Elisabeth M.J., primary, Rijnink, Emilie C., additional, Zandbergen, Malu, additional, Diaz de Pool, Juan D.N., additional, Almekinders, Mathilde M., additional, Berden, Jo H.M., additional, Bijl, Marc, additional, Hagen, Ernst C., additional, Kolster-Bijdevaate, Clara, additional, Steup-Beekman, Gerda M., additional, Wolterbeek, Ron, additional, Bloemenkamp, Kitty W.M., additional, Baelde, Hans J., additional, Bruijn, Jan A., additional, Bajema, Ingeborg M., additional, and Wilhelmus, Suzanne, additional

Published
2021
Full Text
View/download PDF

6. Developments in the Histopathological Classification of ANCA-Associated Glomerulonephritis

Author

van Daalen, Emma E., primary, Wester Trejo, Maria A.C., additional, Göçeroğlu, Arda, additional, Ferrario, Franco, additional, Joh, Kensuke, additional, Noël, Laure-Hélène, additional, Ogawa, Yayoi, additional, Wilhelmus, Suzanne, additional, Ball, Miriam J., additional, Honsova, Eva, additional, Hruskova, Zdenka, additional, Kain, Renate, additional, Kimura, Tomoyoshi, additional, Kollar, Marek, additional, Kronbichler, Andreas, additional, Lindhard, Kristine, additional, Puéchal, Xavier, additional, Salvatore, Steven, additional, Szpirt, Wladimir, additional, Takizawa, Hideki, additional, Tesar, Vladimir, additional, Berden, Annelies E., additional, Dekkers, Olaf M., additional, Hagen, E. Christiaan, additional, Oosting, Jan, additional, Rahmattulla, Chinar, additional, Wolterbeek, Ron, additional, Bos, Willem Jan, additional, Bruijn, Jan A., additional, and Bajema, Ingeborg M., additional

Published
2020
Full Text
View/download PDF

8. 120. DIFFERENCES IN RENAL HISTOPATHOLOGY BETWEEN PR3-ANCA-ASSOCIATED VASCULITIS AND MPO-ANCA-ASSOCIATED VASCULITIS

Author

Trejo, Maria Wester, primary, van Daalen, Emma, additional, Wolterbeek, Ron, additional, Ferrario, Franco, additional, Joh, Kensuke, additional, Noël, Laure- Hélène, additional, Ogawa, Yayoi, additional, Wilhelmus, Suzanne, additional, Ball, Miriam, additional, Honsova, Eva, additional, Hrušková, Zdenka, additional, Kain, Renate, additional, Kronbichler, Andreas, additional, Rasmussen, Kristine Lindhard, additional, Puéchal, Xavier, additional, Salvatore, Steven, additional, Szpirt, Wladimir, additional, Tesar, Vladimir, additional, Berden, Annelies, additional, Bruijn, Jan, additional, and Bajema, Ingeborg, additional

Published
2019
Full Text
View/download PDF

9. 118. VALIDATION OF THE RENAL RISK SCORE FOR ANCA-ASSOCIATED GLOMERULONEPHRITIS

Author

Van Daalen, Emma E, primary, Wester Trejo, Maria A C, additional, Göçeroǧlu, Arda, additional, Ferrario, Franco, additional, Joh, Kensuke, additional, Noël, Laure-Hélène, additional, Ogawa, Yayoi, additional, Wilhelmus, Suzanne, additional, Ball, Miriam J F, additional, Honsova, Eva, additional, Hruskova, Zdenka, additional, Kain, Renate, additional, Kimura, Tomoyoshi, additional, Kollar, Marek, additional, Kronbichler, Andreas, additional, Lindhard, Kristine, additional, Puéchal, Xavier, additional, Salvatore, Steven, additional, Szpirt, Wladimir, additional, Tesar, Vladimir, additional, Berden, Annelies E, additional, Wolterbeek, Ron, additional, Jan Bos, Willem, additional, Bruijn, Jan A, additional, and Bajema, Ingeborg M, additional

Published
2019
Full Text
View/download PDF

10. Revision of the International Society of Nephrology/Renal Pathology Society classification for lupus nephritis: clarification of definitions, and modified National Institutes of Health activity and chronicity indices

Author

Bajema, Ingeborg M., primary, Wilhelmus, Suzanne, additional, Alpers, Charles E., additional, Bruijn, Jan A., additional, Colvin, Robert B., additional, Cook, H. Terence, additional, D’Agati, Vivette D., additional, Ferrario, Franco, additional, Haas, Mark, additional, Jennette, J. Charles, additional, Joh, Kensuke, additional, Nast, Cynthia C., additional, Noël, Laure-Hélène, additional, Rijnink, Emilie C., additional, Roberts, Ian S.D., additional, Seshan, Surya V., additional, Sethi, Sanjeev, additional, and Fogo, Agnes B., additional

Published
2018
Full Text
View/download PDF

12. WS9_1 International Validation Study for the Histopathological Classification of ANCA-Associated Glomerulonephritis (AAGN)

Author

van Daalen, Emma Elisabeth, primary, Ferrario, Franco, additional, Noel, Laure-Helene, additional, Joh, Kensuke, additional, Ogawa, Yayoi, additional, Wilhelmus, Suzanne, additional, Kronbichler, Andreas, additional, Kain, Renate, additional, Salvatore, Steven, additional, Puechal, Xavier, additional, Szpirt, Wladimir, additional, Berden, Annelies, additional, Bruijn, Jan Anthonie, additional, and Bajema, Ingeborg, additional

Published
2017
Full Text
View/download PDF

13. The Revisited Classification of GN in SLE at 10 Years

Author

Wilhelmus, Suzanne, primary, Alpers, Charles E., additional, Cook, H. Terence, additional, Ferrario, Franco, additional, Fogo, Agnes B., additional, Haas, Mark, additional, Joh, Kensuke, additional, Noël, Laure-Hélène, additional, Seshan, Surya V., additional, Bruijn, Jan A., additional, and Bajema, Ingeborg M., additional

Published
2015
Full Text
View/download PDF

15. Lupus nephritis management guidelines compared

Author

Wilhelmus, Suzanne, primary, Bajema, Ingeborg M., additional, Bertsias, George K., additional, Boumpas, Dimitrios T., additional, Gordon, Caroline, additional, Lightstone, Liz, additional, Tesar, Vladimir, additional, and Jayne, David R., additional

Published
2015
Full Text
View/download PDF

18. 118. Validation of the Renal Risk Score for ANCA-Associated Glomerulonephritis.

Author

Daalen, Emma E Van, Trejo, Maria A C Wester, Göçeroǧlu, Arda, Ferrario, Franco, Joh, Kensuke, Noël, Laure-Hélène, Ogawa, Yayoi, Wilhelmus, Suzanne, Ball, Miriam J F, Honsova, Eva, Hruskova, Zdenka, Kain, Renate, Kimura, Tomoyoshi, Kollar, Marek, Kronbichler, Andreas, Lindhard, Kristine, Puéchal, Xavier, Salvatore, Steven, Szpirt, Wladimir, and Tesar, Vladimir

Subjects
CONFERENCES & conventions, GLOMERULONEPHRITIS, RESEARCH methodology, RISK assessment, ANTINEUTROPHIL cytoplasmic antibodies
Published
2019
Full Text
View/download PDF

20. Increased microchimerism in peripheral blood of women with systemic lupus erythematosus: relation with pregnancy.

Author

Bos EMJ, Rijnink EC, Zandbergen M, Diaz de Pool JDN, Almekinders MM, Berden JHM, Bijl M, Hagen EC, Kolster-Bijdevaate C, Steup-Beekman GM, Wolterbeek R, Bloemenkamp KWM, Baelde HJ, Bruijn JA, Bajema IM, and Wilhelmus S

Subjects
Pregnancy, Humans, Female, Chimerism, Leukocytes, Mononuclear, Real-Time Polymerase Chain Reaction, Lupus Erythematosus, Systemic diagnosis, Lupus Erythematosus, Systemic genetics, Pregnancy Complications
Abstract

Objectives: We aimed to determine the presence, amount and origin of microchimerism in peripheral blood of pregnant and non-pregnant parous women with systemic lupus erythematosus (SLE) as compared to control subjects., Methods: We performed a comparative study in which peripheral blood was drawn from eleven female non-pregnant SLE-patients and 22 control subjects, and from six pregnant SLE-patients and eleven control subjects during gestation and up to six months postpartum. Quantitative PCR for insertion-deletion polymorphisms and null alleles was used to detect microchimerism in peripheral blood mononuclear cells and granulocytes., Results: Microchimerism was detected more often in non-pregnant SLE-patients than control subjects (54.4% vs. 13.6%, respectively; p=0.03). When present, the median total number of foetal chimeric cells was 5 gEq/106 in patients and 2.5gEq/106 in control subjects (p=0.048). Microchimerism was mostly foetal in origin; maternal microchimerism was detected in one patient and one control subject. In control subjects, microchimerism was always derived from only one source whereas in 50% of patients it originated from multiple sources. The pregnant patients had a significantly higher median number of foetal chimeric cells in the granulocyte fraction just after delivery than control subjects (7.5 gEq/106 vs. 0 gEq/106, respectively; p=0.02)., Conclusions: Just after delivery, SLE-patients had more microchimerism than control subjects. Three months post-partum, microchimerism was no longer detectable, only to reappear many years after the last pregnancy, more often and at higher levels in SLE-patients than in control subjects. This suggests that these chimeric cells may originate from non-circulating foetal chimeric stem cells.

Published
2022
Full Text
View/download PDF

21. Tissue microchimerism is increased during pregnancy: a human autopsy study.

Author

Rijnink EC, Penning ME, Wolterbeek R, Wilhelmus S, Zandbergen M, van Duinen SG, Schutte J, Bruijn JA, and Bajema IM

Subjects
Adolescent, Adult, Antigens, CD34 metabolism, Brain metabolism, CD3 Complex metabolism, Female, Humans, In Situ Hybridization, In Vitro Techniques, Liver metabolism, Lung metabolism, Middle Aged, Pregnancy, Spleen metabolism, Young Adult, Autopsy, Chimerism, Chromosomes, Human, Y genetics
Abstract

Microchimerism is the occurrence of small populations of cells with a different genetic background within an individual. Tissue microchimerism is considered to be primarily pregnancy-derived and is often studied relative to female-dominant autoimmune diseases, pregnancy complications, malignancies, response to injury, and transplantation outcomes. A particular distribution pattern of chimeric cells across various organs was recently described in a model of murine pregnancies. Our aim was to determine the frequency and distribution of tissue microchimerism across organs during and after pregnancy in humans. We performed in situ hybridization of the Y chromosome on paraffin-embedded autopsy samples of kidneys, livers, spleens, lungs, hearts and brains that were collected from 26 women who died while pregnant or within 1 month after delivery of a son. Frequencies of chimeric cells in various tissues were compared with those of a control group of non-pregnant women who had delivered sons. Tissue microchimerism occurred significantly more frequently in the lungs, spleens, livers, kidneys and hearts of pregnant women compared with non-pregnant women (all P < 0.01). We showed that some of the chimeric cells were CD3+ or CD34+. After correction for cell density, the lung was most chimeric (470 Y chromosome-positive nuclei per million nuclei scored), followed by the spleen (208 Y+/10(6) nuclei), liver (192 Y+/10(6) nuclei), kidney (135 Y+/10(6) nuclei), brain (85 Y+/10(6) nuclei) and heart (40 Y+/10(6) nuclei). Data from this unique study group of women who died while pregnant or shortly after delivery provide information about the number and physiologic distribution of chimeric cells in organs of pregnant women. We demonstrate that during pregnancy, a boost of chimeric cells is observed in women, with a distribution across organs, that parallels findings in mouse models., (© The Author 2015. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results