1. A systematic review of the validity of non-invasive sleep-measuring devices in mid-to-late life adults: Future utility for Alzheimer’s disease research
- Author
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Sebastian Francis Green, Tory Frame, Luke Vikram Banerjee, Amy Gimson, Jonathan Blackman, Hamish Morrison, Katie Lloyd, Sarah Rudd, William George Frederick Fotherby, Ullrich Bartsch, Shaun Purcell, Matt Jones, and Liz Coulthard
- Subjects
Adult ,Sleep Wake Disorders ,Pulmonary and Respiratory Medicine ,slow wave ,NREM ,hypopnoea ,Polysomnography ,apnoea ,Oxygen ,Neurology ,Alzheimer Disease ,Physiology (medical) ,Ageing and Movement Research Group ,REM ,Humans ,Neurology (clinical) ,Sleep ,Alzheimer’s - Abstract
Changes in sleep during mid-to-late life are associated with risk for Alzheimer’s disease (AD). Mechanistic understanding of this association necessitates measurement tools able to quantify these sleep changes longitudinally and accurately. We conducted a systematic review with meta-analysis of validity studies of non-invasive sleep-measuring devices published since 2015 that record sleep metrics associated with AD in adults over 40 (mean 52.9, SD 6.1 years). We reviewed 52 studies, including 32 wearable and ten non-wearable single or multi-sensor devices validated against polysomnography (minimum one night). The apnoea hypopnoea index and oxygen desaturation index were accurately measured across devices. Total sleep time and sleep efficiency were significantly overestimated (p
- Published
- 2022