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1. Duale Schriftnutzung: Brailleschrift und Schwarzschrift

Author

Winter, Fabian

Subjects
dual-media, Brailleschrift, duale Schriftnutzung, Blinden- und Sehbehindertenpädagogik, Schriftspracherwerb, Blindheit, Sehbeeinträchtigung, bic Book Industry Communication::J Society & social sciences::JN Education, bic Book Industry Communication::C Language::CJ Language teaching & learning (other than ELT)
Abstract

In diesem Open-Access-Buch werden die schriftsprachlichen Kompetenzen von Schülerinnen und Schülern mit dualer Schriftnutzung untersucht. Von einem dualen Schriftspracherwerb spricht man, wenn Kinder oder Jugendliche mit Sehbeeinträchtigung neben der Schwarzschrift auch die Brailleschrift erlernen. Vom Erwerb eines zusätzlichen Schriftmediums profitieren insbesondere Lernende mit fortschreitenden oder schwerwiegenden Augenerkrankungen. Wie wirkt sich ein dualer Schriftspracherwerb auf die Leseflüssigkeit, die Rechtschreibung bzw. das Lese- und Hörverstehen aus? Wie können Kinder und Jugendliche mit dualer Schriftnutzung gefördert werden? Um diese Fragen zu beantworten, werden die Ergebnisse aus einer Kompetenzerhebung sowie mehreren Fallstudien herangezogen und mit dem aktuellen Kenntnis- und Forschungsstand zur dualen Schriftnutzung verknüpft. Dazu werden praktische und anschauliche Beispiele geliefert, wie der Unterricht von Kindern und Jugendlichen mit dualer Schriftnutzung gelingen kann.

Published
2022
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3. Correction to: Implementation of a 7T Epilepsy Task Force consensus imaging protocol for routine presurgical epilepsy work-up: effect on diagnostic yield and lesion delineation

Author

Hangel, Gilbert, Kasprian, Gregor, Chambers, Stefanie, Haider, Lukas, Lazen, Philipp, Koren, Johannes, Diehm, Robert, Moser, Katharina, Tomschik, Matthias, Wais, Jonathan, Winter, Fabian, Zeiser, Vitalij, Gruber, Stephan, Aull-Watschinger, Susanne, Traub-Weidinger, Tatjana, Baumgartner, Christoph, Feucht, Martha, Dorfer, Christian, Bogner, Wolfgang, Trattnig, Siegfried, Pataraia, Ekaterina, and Roessler, Karl

Published
2024
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4. Implementation of a 7T Epilepsy Task Force consensus imaging protocol for routine presurgical epilepsy work-up: effect on diagnostic yield and lesion delineation

Author

Hangel, Gilbert, Kasprian, Gregor, Chambers, Stefanie, Haider, Lukas, Lazen, Philipp, Koren, Johannes, Diehm, Robert, Moser, Katharina, Tomschik, Matthias, Wais, Jonathan, Winter, Fabian, Zeiser, Vitalij, Gruber, Stephan, Aull-Watschinger, Susanne, Traub-Weidinger, Tatjana, Baumgartner, Christoph, Feucht, Martha, Dorfer, Christian, Bogner, Wolfgang, Trattnig, Siegfried, Pataraia, Ekaterina, and Roessler, Karl

Published
2024
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11. Observing many researchers using the same data and hypothesis reveals a hidden universe of uncertainty

Author

Breznau, Nate, Rinke, Eike Mark, Wuttke, Alexander, Nguyen, Hung H. V., Adem, Muna, Adriaans, Jule, Alvarez-Benjumea, Amalia, Andersen, Henrik K., Auer, Daniel, Azevedo, Flavio, Bahnsen, Oke, Balzer, Dave, Bauer, Gerrit, Bauer, Paul C., Baumann, Markus, Baute, Sharon, Benoit, Verena, Bernauer, Julian, Berning, Carl, Berthold, Anna, Bethke, Felix S., Biegert, Thomas, Blinzler, Katharina, Blumenberg, Johannes N., Bobzien, Licia, Bohman, Andrea, Bol, Thijs, Bostic, Amie, Brzozowska, Zuzanna, Burgdorf, Katharina, Burger, Kaspar, Busch, Kathrin B., Carlos-Castillo, Juan, Chan, Nathan, Christmann, Pablo, Connelly, Roxanne, Czymara, Christian S., Damian, Elena, Ecker, Alejandro, Edelmann, Achim, Eger, Maureen A., Ellerbrock, Simon, Forke, Anna, Forster, Andrea, Gaasendam, Chris, Gavras, Konstantin, Gayle, Vernon, Gessler, Theresa, Gnambs, Timo, Godefroidt, Amélie, Grömping, Max, Groß, Martin, Gruber, Stefan, Gummer, Tobias, Hadjar, Andreas, Heisig, Jan Paul, Hellmeier, Sebastian, Heyne, Stefanie, Hirsch, Magdalena, Hjerm, Mikael, Hochman, Oshrat, Hövermann, Andreas, Hunger, Sophia, Hunkler, Christian, Huth, Nora, Ignácz, Zsófia S., Jacobs, Laura, Jacobsen, Jannes, Jaeger, Bastian, Jungkunz, Sebastian, Jungmann, Nils, Kauff, Mathias, Kleinert, Manuel, Klinger, Julia, Kolb, Jan-Philipp, Kołczyńska, Marta, Kuk, John, Kunißen, Katharina, Sinatra, Dafina Kurti, Langenkamp, Alexander, Lersch, Philipp M., Löbel, Lea-Maria, Lutscher, Philipp, Mader, Matthias, Madia, Joan E., Malancu, Natalia, Maldonado, Luis, Marahrens, Helge, Martin, Nicole, Martinez, Paul, Mayerl, Jochen, Mayorga, Oscar J., McManus, Patricia, McWagner, Kyle, Meeusen, Cecil, Meierrieks, Daniel, Mellon, Jonathan, Merhout, Friedolin, Merk, Samuel, Meyer, Daniel, Micheli, Leticia, Mijs, Jonathan, Moya, Cristóbal, Neunhoeffer, Marcel, Nüst, Daniel, Nygård, Olav, Ochsenfeld, Fabian, Otte, Gunnar, Pechenkina, Anna O., Prosser, Christopher, Raes, Louis, Ralston, Kevin, Ramos, Miguel R., Roets, Arne, Rogers, Jonathan, Ropers, Guido, Samuel, Robin, Sand, Gregor, Schachter, Ariela, Schaeffer, Merlin, Schieferdecker, David, Schlueter, Elmar, Schmidt, Regine, Schmidt, Katja M., Schmidt-Catran, Alexander, Schmiedeberg, Claudia, Schneider, Jürgen, Schoonvelde, Martijn, Schulte-Cloos, Julia, Schumann, Sandy, Schunck, Reinhard, Schupp, Jürgen, Seuring, Julian, Silber, Henning, Sleegers, Willem, Sonntag, Nico, Staudt, Alexander, Steiber, Nadia, Steiner, Nils, Sternberg, Sebastian, Stiers, Dieter, Stojmenovska, Dragana, Storz, Nora, Striessnig, Erich, Stroppe, Anne-Kathrin, Teltemann, Janna, Tibajev, Andrey, Tung, Brian, Vagni, Giacomo, Van Assche, Jasper, van der Linden, Meta, van der Noll, Jolanda, Van Hootegem, Arno, Vogtenhuber, Stefan, Voicu, Bogdan, Wagemans, Fieke, Wehl, Nadja, Werner, Hannah, Wiernik, Brenton M., Winter, Fabian, Wolf, Christof, Yamada, Yuki, Zhang, Nan, Ziller, Conrad, Zins, Stefan, and Żółtak, Tomasz

Published
2022

21. REPLY TO NIELSEN ET AL. : Social mindfulness is associated with countries’ environmental performance and individual environmental concern

Author

Van Doesum, Niels J., Murphy, Ryan O., Gallucci, Marcello, Aharonov-Majar, Efrat, Athenstaedt, Ursula, Au, Wing Tung, Bai, Liying, Böhm, Robert, Bovina, Inna, Buchan, Nancy R., Chen, Xiao-Ping, Dumont, Kitty B., Engelmann, Jan B., Eriksson, Kimmo, Euh, Hyun, Fiedler, Susann, Friesen, Justin, Gächter, Simon, Garcia, Camilo, González, Roberto, Graf, Sylvie, Growiec, Katarzyna, Guimond, Serge, Hřebíčková, Martina, Immer-Bernold, Elizabeth, Joireman, Jeff, Karagonlar, Gokhan, Kawakami, Kerry, Kiyonari, Toko, Kou, Yu, Kyrtsis, Alexandros-Andreas, Lay, Siugmin, Leonardelli, Geoffrey J., Li, Norman P., Li, Yang, Maciejovsky, Boris, Manesi, Zoi, Mashuri, Ali, Mok, Aurelia, Moser, Karin S., Moták, Ladislav, Netedu, Adrian, Platow, Michael J., Raczka-Winkler, Karolina, Folmer, Christopher P. Reinders, Reyna, Cecilia, Romano, Angelo, Shalvi, Shaul, Simão, Cláudia, Stivers, Adam W., Strimling, Pontus, Tsirbas, Yannis, Utz, Sonja, van der Meij, Leander, Waldzus, Sven, Wang, Yiwen, Weber, Bernd, Weisel, Ori, Wildschut, Tim, Winter, Fabian, Wu, Junhui, Yong, Jose C., and Van Lange, Paul A. M.

Published
2022

22. REPLY TO KOMATSU ET AL. : From local social mindfulness to global sustainability efforts?

Author

Van Doesum, Niels J., Murphy, Ryan O., Galluccie, Marcello, Aharonov-Majar, Efrat, Athenstaedt, Ursula, Au, Wing Tung, Baii, Liying, Böhm, Robert, Bovina, Inna, Buchan, Nancy R., Chen, Xiao-Ping, Dumont, Kitty B., Engelmann, Jan B., Eriksson, Kimmo, Euh, Hyun, Fiedler, Susann, Friesen, Justin, Gächter, Simon, Garcia, Camilo, González, Roberto, Graf, Sylvie, Growieca, Katarzyna, Guimond, Serge, Hřebíčková, Martina, Immer-Bernold, Elizabeth, Joireman, Jeff, Karagonlar, Gokhan, Kawakami, Kerry, Kiyonari, Toko, Kou, Yu, Kyrtsis, Alexandros-Andreas, Lay, Siugmin, Leonardelli, Geoffrey J., Li, Norman P., Lin, Yang, Maciejovsky, Boris, Manesi, Zoi, Mashuri, Ali, Mok, Aurelia, Moser, Karin S., Moták, Ladislav, Netedu, Adrian, Platow, Michael J., Raczka-Winkler, Karolina, Folmer, Christopher P. Reinders, Reynab, Cecilia, Romano, Angelo, Shalvi, Shaul, Simão, Cláudia, Stivers, Adam W., Strimling, Pontus, Tsirbas, Yannis, Utz, Sonja, van der Meijh, Leander, Waldzus, Sven, Wang, Yiwen, Weber, Bernd, Weisel, Ori, Wildschut, Tim, Winter, Fabian, Wu, Junhui, Yong, Jose C., and Van Lange, Paul A. M.

Published
2022

34. Social mindfulness and prosociality vary across the globe

Author

Van Doesum, Niels J., Murphy, Ryan O., Gallucci, Marcello, Aharonov-Majar, Efrat, Athenstaedt, Ursula, Au, Wing Tung, Bai, Liying, Böhm, Robert, Bovina, Inna, Buchan, Nancy R., Chen, Xiao-Ping, Dumont, Kitty B., Engelmann, Jan B., Eriksson, Kimmo, Euh, Hyun, Fiedler, Susann, Friesen, Justin, Gächter, Simon, Garcia, Camilo, González, Roberto, Graf, Sylvie, Growiec, Katarzyna, Guimond, Serge, Hřebíčková, Martina, Immer-Bernold, Elizabeth, Joireman, Jeff, Karagonlar, Gokhan, Kawakami, Kerry, Kiyonari, Toko, Kou, Yu, Kuhlman, D. Michael, Kyrtsis, Alexandros-Andreas, Lay, Siugmin, Leonardelli, Geoffrey J., Li, Norman P., Li, Yang, Maciejovsky, Boris, Manesi, Zoi, Mashuri, Ali, Mok, Aurelia, Moser, Karin S., Moták, Ladislav, Netedu, Adrian, Pammi, Chandrasekhar, Platow, Michael J., Raczka-Winkler, Karolina, Folmer, Christopher P. Reinders, Reyna, Cecilia, Romano, Angelo, Shalvi, Shaul, Simão, Cláudia, Stivers, Adam W., Strimling, Pontus, Tsirbas, Yannis, Utz, Sonja, van der Meij, Leander, Waldzus, Sven, Wang, Yiwen, Weber, Bernd, Weisel, Ori, Wildschut, Tim, Winter, Fabian, Wu, Junhui, Yong, Jose C., and Van Lange, Paul A. M.

Published
2021

38. A navigated, robot-driven laser craniotomy tool for frameless depth electrode implantation. An in-vivo recovery animal study

Author

Winter, Fabian, primary, Pilz, Patrick, additional, Kramer, Anne M., additional, Beer, Daniel, additional, Gono, Patrick, additional, Morawska, Marta, additional, Hainfellner, Johannes, additional, Klotz, Sigrid, additional, Tomschik, Matthias, additional, Pataraia, Ekaterina, additional, Hangel, Gilbert, additional, Dorfer, Christian, additional, and Roessler, Karl, additional

Published
2024
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44. Exopeptidase combination enhances the degradation of isotopically labelled gluten immunogenic peptides in humans.

Author

Mourabit, Sulayman, Römer, Sarah, Bonner, Erin R., Winter, Fabian, Tschollar, Julian, Tzvetkov, Mladen V., Weitschies, Werner, Engeli, Stefan, and Tschollar, Werner

Subjects
PEPTIDES, AMINO acids, GLUTEN, CELIAC disease, BLOOD plasma
Abstract

Introduction: Celiac disease is a common autoimmune-like enteropathy caused by an aberrant response to incompletely digested dietary gluten. Gluten immunogenic peptides including the immunodominant 33-mer are thought to be resistant to proteolytic digestion by human gastrointestinal peptidases. We developed a novel enzyme therapy approach to support gluten peptide digestion using a combination of two tandem-acting exopeptidases, AMYNOPEP, that complement the intrinsic enzymatic activity of intestinal brush border enterocytes. Methods: We evaluated the effects of AMYNOPEP supplementation on 33-mer degradation in vitro and in vivo. In a cross-over clinical study, healthy volunteers with no gastrointestinal disorders were given stable isotope (SI) labelled 33-mer peptides in the presence of varying peptide substrates and caloric loads, with and without AMYNOPEP. 33-mer degradation products (SI-labelled single amino acids) were measured in the blood plasma using LC-MS/MS. Results: AMYNOPEP achieved rapid, complete amino-to-carboxyl terminal degradation of the 33-mer in vitro, generating single amino acids and dipeptides. In healthy volunteers, AMYNOPEP supplementation significantly increased 33-mer degradation and absorption of SI-labelled amino acids even in the presence of competing substrates. Specifically, we observed a 2.8-fold increase in the Cmax of stable isotope-labelled amino acids in the presence of wheat gluten. The absorption kinetics of labelled amino acids derived from 33- mer digestion with AMYNOPEP closely resembled that of SI-labelled X-Proline dipeptides administered without enzyme supplementation, highlighting the rapid hydrolytic activity of AMYNOPEP on polypeptides. Conclusions: AMYNOPEP achieved complete degradation of the 33-mer into single amino acids and dipeptides in vitro and significantly improved 33-mer degradation kinetics in healthy volunteers, as measured by labelled amino acid detection, warranting further investigation into the potential therapeutic benefits of exopeptidase combinations for patients with gluten-related health disorders including celiac disease. [ABSTRACT FROM AUTHOR]

Published
2024
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