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This paper presents the use of the kinetic impact technique to deflect asteroids that may present some risk of collision with Earth. Within the work to be developed here, we intend to evaluate in more detail the possibility to deflect the orbit of the asteroid 101955 Bennu by applying variations in its velocity ([Formula: see text]v) at different positions along its orbital period and measuring effects of close encounters with planet Earth. We will see that, in a relatively long period of time, the asteroid has several close encounters with the planet, thus suffering a natural gravitational perturbation. With the application of the impulses, the relative distances change, causing variations in the energy of the asteroid and a large variation in the relative distance between the asteroid and Earth over a long period after the impulse. We present results related to the magnitude of the impulse applied, which is important because its defines the mass and velocity of the impactor to be considered. Then, we mapped the positions of the impulses along a period of the orbit of the asteroid. We finish by explaining what happens to the orbit of the asteroid during the periods of gravitational perturbation, since the close encounters amount to "Swing Bys" that intensify the variations of the relative distances between the bodies after the impulse is applied., (© 2022. The Author(s).)

Low pH in tissue can evoke pain in animals and humans, and is an important factor in hyperalgesia. Research has also implicated acidosis in psychiatric and neurological diseases. One emerging class of pH-detecting receptors is that of the acid-sensing ion channels (ASICs). Advances in ASIC research have improved the understanding of the role played by pH dynamics in physiological and pathophysiological processes. Increasing evidence suggests that targeting ASICs with pharmacological agents may offer an effective and novel approach for treating pain and diseases of the CNS. However, the development of pharmaceuticals that target ASICs and are suitable for clinical use remains an obstacle. This review provides an update on ASICs and their potential for therapeutic modification in pain and CNS diseases.