134 results on '"Wissow L"'
Search Results
2. Converging on child mental health – toward shared global action for child development
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Belkin, G., primary, Wissow, L., additional, Lund, C., additional, Aber, L., additional, Bhutta, Z., additional, Black, M., additional, Kieling, C., additional, McGregor, S., additional, Rahman, A., additional, Servili, C., additional, Walker, S., additional, and Yoshikawa, H., additional
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- 2017
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3. Factors promoting and inhibiting sustained impact of a mental health task-shifting program for HIV providers in Ethiopia
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Jerene, D., primary, Biru, M., additional, Teklu, A., additional, Rehman, T., additional, Ruff, A., additional, and Wissow, L., additional
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- 2017
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4. Generating evidence to narrow the treatment gap for mental disorders in sub-Saharan Africa: rationale, overview and methods of AFFIRM
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Lund, C., primary, Alem, A., additional, Schneider, M., additional, Hanlon, C., additional, Ahrens, J., additional, Bandawe, C., additional, Bass, J., additional, Bhana, A., additional, Burns, J., additional, Chibanda, D., additional, Cowan, F., additional, Davies, T., additional, Dewey, M., additional, Fekadu, A., additional, Freeman, M., additional, Honikman, S., additional, Joska, J., additional, Kagee, A., additional, Mayston, R., additional, Medhin, G., additional, Musisi, S., additional, Myer, L., additional, Ntulo, T., additional, Nyatsanza, M., additional, Ofori-Atta, A., additional, Petersen, I., additional, Phakathi, S., additional, Prince, M., additional, Shibre, T., additional, Stein, D. J., additional, Swartz, L., additional, Thornicroft, G., additional, Tomlinson, M., additional, Wissow, L., additional, and Susser, E., additional
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- 2015
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5. Collaboratively reframing mental health for integration of HIV care in Ethiopia
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Wissow, L. S., primary, Tegegn, T., additional, Asheber, K., additional, McNabb, M., additional, Weldegebreal, T., additional, Jerene, D., additional, and Ruff, A., additional
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- 2014
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6. Coding patient emotional cues and concerns in medical consultations: The Verona coding definitions of emotional sequences (VR-CoDES).
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Zimmermann, C, Del Piccolo, L, Bensing, J, Bergvik, S, de Haes, H, Eide, H, Fletcher, Ian, Goss, C, Heaven, C, Humpheris, G, Kim, YM, Langewitz, W, Meeuwesen, L, Nuebling, M, Rimondini, M, Salmon, P, van Dulmen, S, Wissow, L, Zandbelt, L, Finset, A, Zimmermann, C, Del Piccolo, L, Bensing, J, Bergvik, S, de Haes, H, Eide, H, Fletcher, Ian, Goss, C, Heaven, C, Humpheris, G, Kim, YM, Langewitz, W, Meeuwesen, L, Nuebling, M, Rimondini, M, Salmon, P, van Dulmen, S, Wissow, L, Zandbelt, L, and Finset, A
- Abstract
Objective To present the Verona Coding Definitions of Emotional Sequences (VR-CoDES CC), a consensus based system for coding patient expressions of emotional distress in medical consultations, defined as Cues or Concerns. Methods The system was developed by an international group of communication researchers. First, consensus was reached in different steps. Second, a reliability study was conducted on 20 psychiatric consultations. Results A Cue is defined as a verbal or non-verbal hint which suggests an underlying unpleasant emotion that lacks clarity. A Concern is defined as a clear and unambiguous expression of an unpleasant current or recent emotion that is explicitly verbalized with or without a stated issue of importance. The conceptual framework sets precise criteria for cues and concerns and for whom (health provider or patient) elicits the cue/concern. Inter-rater reliability proved satisfactory (agreement 81.5%, Cohen's Kappa 0.70). Conclusion The VR-CoDES CC will facilitate comparative research on provider–patient communication sequences in which patients express emotional distress. Practice implications The VR-CoDES CC may be used to help clinicians in recognizing or facilitating cues and concerns, thereby improving the recognition of patients’ emotional distress, the therapeutic alliance and quality of care for these patients.
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- 2011
7. Development of the Verona coding definitions of emotional sequences to code health providers’ responses (VR-CoDES-P) to patient cues and concerns.
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Del Piccolo, L, de Haes, H, Heaven, C, Jansen, J, Verheul, W, Bensing, J, Bergvik, S, Deveugele, M, Eide, H, Fletcher, Ian, Goss, C, Humpheris, G, Kim, YM, Langewitz, W, Mazzi, M, Mjaaland, T, Moretti, F, Nuebling, M, Rimondini, M, Salmon, P, Sibbern, T, Skre, I, van Dulmen, S, Wissow, L, Young, B, Zandbelt, L, Del Piccolo, L, de Haes, H, Heaven, C, Jansen, J, Verheul, W, Bensing, J, Bergvik, S, Deveugele, M, Eide, H, Fletcher, Ian, Goss, C, Humpheris, G, Kim, YM, Langewitz, W, Mazzi, M, Mjaaland, T, Moretti, F, Nuebling, M, Rimondini, M, Salmon, P, Sibbern, T, Skre, I, van Dulmen, S, Wissow, L, Young, B, and Zandbelt, L
- Abstract
Objective To present a method to classify health provider responses to patient cues and concerns according to the VR-CoDES-CC (Del Piccolo et al. (2009) [2] and Zimmermann et al. (submitted for publication) [3]). The system permits sequence analysis and a detailed description of how providers handle patient's expressions of emotion. Methods The Verona-CoDES-P system has been developed based on consensus views within the “Verona Network of Sequence Analysis”. The different phases of the creation process are described in detail. A reliability study has been conducted on 20 interviews from a convenience sample of 104 psychiatric consultations. Results The VR-CoDES-P has two main classes of provider responses, corresponding to the degree of explicitness (yes/no) and space (yes/no) that is given by the health provider to each cue/concern expressed by the patient. The system can be further subdivided into 17 individual categories. Statistical analyses showed that the VR-CoDES-P is reliable (agreement 92.86%, Cohen's kappa 0.90 (±0.04) p < 0.0001). Conclusion Once validity and reliability are tested in different settings, the system should be applied to investigate the relationship between provider responses to patients’ expression of emotions and outcome variables. Practice implications Research employing the VR-CoDES-P should be applied to develop research-based approaches to maximize appropriate responses to patients’ indirect and overt expressions of emotional needs.
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- 2011
8. Informed consent for enrolling minors in genetic susceptibility research: a qualitative study of at-risk childrenʼs and parentsʼ views about childrenʼs role in decision-making*1
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GELLER, G, primary, TAMBOR, E, additional, BERNHARDT, B, additional, FRASER, G, additional, and WISSOW, L, additional
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- 2003
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9. Disclosure of HIV diagnosis to children: When, where, why, and how
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GERSON, A, primary, JOYNER, M, additional, FOSARELLI, P, additional, BUTZ, A, additional, WISSOW, L, additional, LEE, S, additional, MARKS, P, additional, and HUTTON, N, additional
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- 2001
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10. Meaning shift: findings from wellness acupuncture.
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Stibich M and Wissow L
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Wellness or holistic acupuncture places an emphasis on working with and developing the patient's understanding of health and illness. This research project examines changes in meaning in 367 letters from successful wellness acupuncture. Mentions of changes of the meaning of health and illness were categorized into themes using content analysis. Five main meaning shifts were identified in the data. These shifts are (1) from a goal of fixing the problem to a goal of increasing health, (2) from symptoms as problems to symptoms as teachers, (3) from healing as passive to healing as active, (4) from being dominated by illness to moving beyond the illness, and (5) from regarding the practitioner as a technician to regarding the practitioner as a healer or friend. The shifts in meaning seen in the data illustrate a potential pathway for bringing health benefits to patients and may provide a useful strategy for healing. Narrative (defined here as 'first-person accounts by respondents of their experience') is thought to play a major role in the manifestation of symptoms and the ability of patients to cope with illness. Patients suffer not only from their primary symptoms, but also from the results and effects of their illnesses, such as depression and changes in their relationships. For the patient, symptoms often hold much meaning beyond physical sensation. A recurrence of symptoms can have other unpleasant results, such as additional trips to doctors, paying for medications, time off from work, not being able to play with children, or changes in relationships with family members. In many cases, the anxiety and depression surrounding the symptoms causes suffering which are greater than the suffering caused by the physical symptoms directly. These factors also change how the ill individual interacts socially, thereby reducing both instrumental and emotional social support, resulting in a downward spiral of suffering. By interacting with narrative, a path to improved health that augments conventional or alternative treatment can be used. Narrative is the point of access to the patient's mental state about illness; it is the manifestation of meaning. Patients express the meaning of their illness in their own narratives. By expressing narratives, patients articulate and develop the meaning of their illness. This process itself can be therapeutic. By shifting the individual's meaning from a detrimental to a beneficial one, a great deal of suffering may be eliminated without any change in the physical sensations. Certain individuals (eg, a socially-sanctioned healer) are given social roles in the ongoing story of someone's illness. These socially sanctioned individuals (ie, physicians) have an important role in interpreting and developing the individual's understanding of his or her illness. Therefore, in addition to physical interventions targeting the cause of the sensations, a great deal of suffering may potentially be alleviated through interacting with the patient's understanding and appraisal of symptoms. Patient meaning shift may be one of the most effective means by which to aid the patient. This article examines patient accounts of acupuncture experience for narrative concerning meaning shifts to gain insight into their role in wellness acupuncture practice. [ABSTRACT FROM AUTHOR]
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- 2006
11. The impact of barriers and self-efficacy on self-care behaviors in type 2 diabetes.
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Aljasem LI, Peyrot M, Wissow L, and Rubin RR
- Abstract
PURPOSE: This cross-sectional, correlational study examined the relationships of diabetes-specific treatment barriers and self-efficacy with self-care behaviors. METHODS: A total of 309 people with type 2 diabetes participated in this study. All of the factors were assessed by self-report questionnaires. Self-care behaviors included exercise, diet, skipping medication, testing blood for glucose, adjusting insulin to avoid or correct hyperglycemia, and adjusting diet to avoid or correct hypoglycemia. RESULTS: Perceived barriers to carrying out self-care behaviors were associated with worse diet and exercise behavior. Greater self-efficacy predicted more frequent blood glucose testing, less frequent skipping of medication and binge eating, and closer adherence to an ideal diet. Nontraditional dimensions of self-efficacy were associated with worse self-care. Self-efficacy explained 4% to 10% of the variance in diabetes self-care behaviors beyond that accounted for by patient characteristics and health beliefs about barriers. CONCLUSIONS: The findings of this study provided support for Rosenstock's proposal that a person's self-perceived capability to carry out a behavior should be incorporated into an expanded health belief model. [ABSTRACT FROM AUTHOR]
- Published
- 2001
12. Partial trisomy 6q, due to balanced maternal translocation (6;22) (q21; p13) or (q21; pter).
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Stamberg, J., Shapiro, J., Valle, D., Kuhajda, F. P., Thomas, G., and Wissow, L.
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- 1981
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13. Patient-provider communication during the emergency department care of children with asthma. The National Cooperative Inner-City Asthma Study, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD.
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Wissow, Lawrence S., Roter, Debra, Bauman, Laurie J., Crain, Ellen, Kercsmar, Carolyn, Weiss, Kevin, Mitchell, Herman, Mohr, Beth, Wissow, L S, Roter, D, Bauman, L J, Crain, E, Kercsmar, C, Weiss, K, Mitchell, H, and Mohr, B
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- 1998
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14. Family violence and the evaluation of behavioral concerns in a pediatric primary care clinic.
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Wissow, Lawrence S., Wilson, Modena E.H., Roter, Debra, Larson, Susan, Berman, Hope I., Wissow, L S, Wilson, M E, Roter, D, Larson, S, and Berman, H I
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- 1992
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15. Poverty, race, and hospitalization for childhood asthma.
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Wissow, L S, primary, Gittelsohn, A M, additional, Szklo, M, additional, Starfield, B, additional, and Mussman, M, additional
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- 1988
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16. So much to be learned about talking with children.
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Polk S and Wissow L
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- 2012
17. From patient education to communication in health care.
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Visser A, Wissow L, Visser, Adriaan, and Wissow, Larry
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- 2003
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18. Enhancing communication skills for pediatric visits through on-line training using video demonstrations
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Wissow Larry, Foy Jane M, Kemper Kathi J, and Shore Steve
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Special aspects of education ,LC8-6691 ,Medicine - Abstract
Abstract Background Training in communication skills for health professionals is important, but there are substantial barriers to individual in-person training for practicing clinicians. We evaluated the feasibility and desirability of on-line training and sought suggestions for future courses. Methods Based on successful in-person curricula for communication skills and our previous on-line curricula, we created an on-line course consisting of 28 modules (4.75 hours CME credit) about communication skills during pediatric visits that included a mental health concern; each module included a brief case, a multiple choice question, an explanation, and a 1–2 minute video demonstrating key skills. Specific communication skills included: greeting, setting an agenda, discussing diagnosis and treatment, and managing negative interactions. The course was announced by emails in spring, 2007; the course was available on-line for 60 days; we aimed to enroll 50 clinicians. Outcomes were analyzed for those who evaluated the course within 75 days of its initial availability. Results Overall, 61 clinicians registered, of whom most were nurses (N = 24), physicians (N = 22), or psychologists or social workers (N = 12). Of the 36 (59%) clinicians who evaluated the course, over 85% agreed that all course objectives had been met; over 90% reported greater confidence in greetings and agenda-setting; and over 80% reported greater confidence in discussing diagnosis and treatment and managing negative interactions. Nearly all, 97% would recommend the course to other clinicians and trainees. Suggestions for improvement included a library of additional video vignettes and written materials to accompany the on-line training. Conclusion On-line training in communication skills for pediatric mental health visits is feasible, desirable and associated with increased confidence in key skills. Positive feedback from clinicians suggests that a comparison of on-line versus in-person training is warranted.
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- 2008
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19. Assessing Provider-Patient-Parent Communication in the Pediatric Emergency Department
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WISSOW, L
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- 2002
20. Mid-life suicide an increasing problem in u.s. Whites, 1999-2005.
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Hu G, Wilcox HC, Wissow L, and Baker SP
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- 2008
21. Coding patient emotional cues and concerns in medical consultations: The Verona coding definitions of emotional sequences (VR-CoDES)
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Zimmermann C, Del Piccolo L, Bensing J, Bergvik S, De Haes H, Eide H, Fletcher I, Goss C, Heaven C, Humphris G, Kim YM, Langewitz W, Meeuwesen L, Nuebling M, Rimondini M, Salmon P, van Dulmen S, Wissow L, Zandbelt L, and Finset A
- Abstract
To present the Verona Coding Definitions of Emotional Sequences (VR-CoDES CC), a consensus based system for coding patient expressions of emotional distress in medical consultations, defined as Cues or Concerns. [ABSTRACT FROM AUTHOR]
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- 2011
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22. Gifts, bribes and solicitions [sic]: print media and the social construction of informal payments to doctors in Taiwan.
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Chiu Y, Smith KC, Morlock L, and Wissow L
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The Taiwanese practice of patients giving informal payments to physicians to secure services is deeply rooted in social and cultural factors. This study examines the portrayal of informal payments by Taiwanese print news media over a period of 12 years-from prior to until after the implementation of national health insurance (NHI) in Taiwan in 1995. The goal of the study was to examine how the advent of NHI changed the rationale for and use of informal payments. Both before and after the introduction of NHI, Taiwanese newspapers portrayed informal payments as appropriate means to secure access to better health care. Newspaper accounts established that, although NHI reduced patients' financial barriers to care, it did not change deeply held cultural beliefs that good care depended on the development of a reciprocal sense of obligation between patients and physicians. Physicians may have also encouraged the ongoing use of informal payments to make up revenue lost when NHI standardized fees and limited income from dispensing medications. In 2002, seven years after the implementation of NHI, the use of informal payments, though illegal, was still being justified in the print media through allusions to its role in traditional Taiwanese culture. [ABSTRACT FROM AUTHOR]
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- 2007
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23. Scale-up of Global Child and Youth Mental Health Services: A Scoping Review.
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Walker SC, Wissow L, Gubner NR, Ngo S, Szatmari P, and Servili C
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- Humans, Child, Adolescent, Global Health, Adolescent Health Services organization & administration, Developing Countries, Mental Health Services organization & administration, Child Health Services organization & administration
- Abstract
Numerous influential policy and scientific bodies are calling for more rapid advances in the scale-up of child and youth mental health services (CYMHS). A number of CYMHS innovations hold promise for advancing scale-up but little is known about how real-world efforts are progressing. We conducted a scoping review to identify promising approaches to CYMHS scale-up across the globe. Searches were completed in six databases (Academic Search Complete, CINAHL, MEDLINE, PsychInfo, PubMed, and Web of Science). Article selection and synthesis were conducted in accordance to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews (PRISMA-ScR) checklist. A second search focused on low-and-middle-income countries (LMIC) was conducted based on the Cochrane Library recommended search filters of the World Bank listed LMIC countries. Authors used a double coding strategy during the title/abstract and full-text review. Twenty-eight articles meeting the eligibility criteria were identified that described 22 initiatives (in 11 different countries). Our review found the majority of published scale-up studies in CYMHS were not informed by scale-up frameworks in design or reporting. The methods and outcomes used in the identified articles were highly variable and limited our ability to draw conclusions about comparative effectiveness although promising approaches emerged. Successes and failures identified in our review largely reflect consensus in the broader literature regarding the need for strategies to better navigate the complexities of system and policy implementation while ensuring CYMHS interventions fit local contexts., (© 2024. The Author(s).)
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- 2024
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24. Relationship between family history of mandatory boarding school experiences and suicide risk in US reservation-based Native American youth: a cross-sectional analysis.
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Brockie T, Wissow L, Campbell JC, Ivanich J, Nelson K, Wallen G, Wetsit L, and Wilcox H
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Introduction: Suicide is a leading cause of death among Native American youth and adolescents in the USA. A myriad of factors have been correlated with risk for suicide ideation (SI)/suicide attempt (SA), including historical trauma; however, accurate measurement of historical trauma has been inconsistent., Objective: To examine the association of family history of a negative mandatory boarding school experience with SI and SAs., Methods: An anonymous online survey was conducted with 288 Native youth aged 15-24 years from the Fort Peck Reservation in Montana. Multinomial regression was applied adjusting for other known risk and protective factors of SI and SAs., Results: Thirty-five percent reported past SAs and 15% reported ideation without prior attempt. Of the 129 (45%) reporting a family history of mandatory boarding school experiences, 28% perceived the experience as positive while 22% as negative. After adjusting for risk and protective factors, both SI and SAs were associated with a family history of negative mandatory boarding school experiences (adjusted OR (AOR)=4.8 and 4.3, respectively) and polydrug use (AOR=3.6 and 2.3). SAs were also associated with post-traumatic stress disorder (AOR=2.6) and depressive symptoms (AOR=3.6)., Conclusion: The association between family history of negative mandatory boarding school experiences and SI and SAs implies that culturally responsive interventions are needed to reduce the intergenerational impacts of historical trauma., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
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- 2024
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25. Youth Mental Health Screening and Linkage to Care.
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Karcher NR, Hicks R, Schiffman J, Asarnow JR, Calkins ME, Dauberman JL, Garrett CD, Koli RL, Larrauri CA, Loewy RL, McGough CA, Murphy JM, Niendam TA, Roaten K, Rodriguez J, Staglin BK, Wissow L, Woodberry KA, Young JF, Gur RE, Bearden CE, and Barch DM
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- Humans, Adolescent, United States, Adult, Mass Screening, Schools, Mental Health, Psychopathology
- Abstract
One Mind, in partnership with Meadows Mental Health Policy Institute, convened several virtual meetings of mental health researchers, clinicians, and other stakeholders in 2020 to identify first steps toward creating an initiative for early screening and linkage to care for youths (individuals in early adolescence through early adulthood, ages 10-24 years) with mental health difficulties, including serious mental illness, in the United States. This article synthesizes and builds on discussions from those meetings by outlining and recommending potential steps and considerations for the development and integration of a novel measurement-based screening process in youth-facing school and medical settings to increase early identification of mental health needs and linkage to evidence-based care. Meeting attendees agreed on an initiative incorporating a staged assessment process that includes a first-stage brief screener for several domains of psychopathology. Individuals who meet threshold criteria on the first-stage screener would then complete an interview, a second-stage in-depth screening, or both. Screening must be followed by recommendations and linkage to an appropriate level of evidence-based care based on acuity of symptoms endorsed during the staged assessment. Meeting attendees proposed steps and discussed additional considerations for creating the first nationwide initiative for screening and linkage to care, an initiative that could transform access of youths to mental health screening and care., Competing Interests: Ms. McGough has served as a conference adviser and board member for Janssen Pharmaceuticals, as an advocacy board member for Alkermes, and as a social media awareness campaign participant for Teva Pharmaceuticals. Dr. Niendam is the founder and a board member of Safari Health Inc. Mr. Staglin is a Mindstrong Health board member. Dr. Young receives royalties from Oxford University Press. Dr. Bearden is on the Novartis Neuroscience Scientific Advisory Board and the One Mind Scientific Advisory Board. The other authors report no financial relationships with commercial interests.
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- 2023
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26. Effect of General Practitioner Training in a Collaborative Child Mental Health Care Program on Children's Mental Health Outcomes in a Low-Resource Setting: A Cluster Randomized Trial.
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Sharifi V, Shahrivar Z, Zarafshan H, Ashezary SB, Arabgol F, Khademi M, Jafarinia M, Hajebi A, Abolhassani F, Emami S, Ashkezari AB, Stuart EA, Mojtabai R, and Wissow L
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- Adult, Adolescent, Humans, Child, Female, Child, Preschool, Male, Mental Health, Iran, Counseling, Outcome Assessment, Health Care, General Practitioners
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Importance: Integrated care for children is rarely studied, especially in low- and middle-income countries, where generalists often provide mental health care., Objectives: To explore the effect of adding a child and youth component to an existing adult collaborative care program on mental health outcomes and receipt of care., Design, Setting, and Participants: This cluster randomized trial was conducted within an adult collaborative care program in Tehran, Iran. General practitioners (GPs), their 5- to 15-year-old patients, and patients' parents were included. Children and youths coming for routine medical visits who scored greater than the cutoff on the Strengths and Difficulties Questionnaire (SDQ) were followed up for 6 months. The study was conducted from May 2018 to October 2019, and analysis was conducted from March 2020 to August 2021., Interventions: GPs were randomized to either a 2.5-day training on managing common child mental health problems (intervention) or refresher training on identification and referral (control)., Main Outcomes and Measures: Primary outcome was change in SDQ total problems score; secondary outcomes included discussion of psychosocial issues by the GPs and receipt of mental health care during the follow-up period., Results: Overall, 49 GPs cared for 389 children who scored greater than the cutoff on the SDQ (216 children in intervention group, 173 in control group). Patients' mean (SD) age was 8.9 (2.9) years (range, 5 to 15 years), and 182 (47%) were female patients. At 6 months, children in the intervention group had greater odds of receiving mental health care during the study (odds ratio [OR], 3.0; 95% CI, 1.1 to 7.7), parents were more likely to report that intervention GPs had discussed parent (OR, 2.1; 95% Cl, 1.1 to 3.8) and child (OR, 2.0; 95% Cl, 0.9 to 4.8) psychosocial issues, and intervention GPs were more likely to say they had provided counseling (OR, 1.8; 95% Cl, 1.02 to 3.3). However, there was no greater improvement in SDQ scores among children seen by intervention vs control GPs. Adjusted for clustering within GP, the variables used for balanced allocation (practice size, practice ownership, and study wave), and the other variables associated with change in SDQ scores over time, there was not a significant time-treatment interaction at either the 3- or 6-month follow-up points (linear combination of coefficients for intervention, 0.57 [95% CI, -1.07 to 2.22] and -0.08 [95%CI, -1.76 to 1.56], respectively). In a subgroup of GPs with practices composed of 50% or more children, children seen by intervention GPs improved to a significantly greater extent (-3.6 points; 95% CI, -6.7 to -0.46 points; effect size d = 0.66; 95% CI, 0.30 to 1.01) compared with those seen by control GPs., Conclusions and Relevance: In this cluster randomized trial, GP training on managing common child mental health problems did not demonstrate greater improvement in child SDQ scores. Child mental health training for GPs in collaborative care can improve children's access to mental health care, but prior experience working with children and their families may be required for GPs to use a brief training in a way that improves child outcomes., Trial Registration: ClinicalTrials.gov Identifier: NCT03144739.
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- 2023
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27. Ineligibility for and Refusal to Participate in Randomized Controlled Trials That Have Studied Impact on Suicide-Related Outcomes in the United States: A Meta-Analysis.
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Susukida R, Amin-Esmaeili M, Ryan TC, Kharrazi H, Wilson RF, Musci RJ, Zhang A, Wissow L, Robinson KA, and Wilcox HC
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- Adolescent, Adult, Female, Humans, Male, Randomized Controlled Trials as Topic, Systematic Reviews as Topic, United States, Refusal to Participate, Suicide Prevention
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Objective: Ineligibility for and refusal to participate in randomized controlled trials (RCTs) can potentially lead to unrepresentative study samples and limited generalizability of findings. We examined the rates of exclusion and refusal in RCTs that have studied impact on suicide-related outcomes in the US., Data Sources: PubMed, the Cochrane Library, the Campbell Collaboration Library of Systematic Reviews, CINAHL, PsycINFO, and Education Resources Information Center were searched from January 1990 to May 2020 using the terms ( suicide prevention ) AND ( clinical trial )., Study Selection: Of 8,403 studies retrieved, 36 RCTs assessing effectiveness on suicide-related outcomes in youth (≤ 25 years old) conducted in the US were included., Data Extraction: Study-level data were extracted by 2 independent investigators for a random-effects meta-analysis and meta-regression., Results: The study participants (N = 13,264) had a mean (SD) age of 14.87 (1.58) years and were 50% male, 23% African American, and 24% Hispanic. The exclusion rate was 36.4%, while the refusal rate was 25.5%. The exclusion rate was significantly higher in the studies excluding individuals not exceeding specified cutoff points of suicide screening tools (51.2%; adjusted linear coefficient [β] = 1.30, standard error [SE] = 0.15; P = .041) and individuals not meeting the age or school grade criterion (45.9%; β = 1.37, SE = 0.13; P = .005)., Conclusions: The rates of exclusion and refusal in youth prevention interventions studying impact on suicide-related outcomes were not as high compared to the rates found in other mental and behavioral interventions. While there was strong racial/ethnic group representation in RCTs examining youth suicide-related outcomes, suicide severity and age limited eligibility., (© Copyright 2022 Physicians Postgraduate Press, Inc.)
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- 2022
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28. Prevalence of depression among HIV-positive pregnant women and its association with adherence to antiretroviral therapy in Addis Ababa, Ethiopia.
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Abebe W, Gebremariam M, Molla M, Teferra S, Wissow L, and Ruff A
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- Adult, Comorbidity, Cross-Sectional Studies, Ethiopia epidemiology, Female, HIV Seropositivity drug therapy, Humans, Medication Adherence, Pregnancy, Pregnancy Complications, Infectious drug therapy, Pregnant Women, Prevalence, Anti-Retroviral Agents therapeutic use, Depressive Disorder epidemiology, HIV Seropositivity epidemiology, Pregnancy Complications, Infectious epidemiology
- Abstract
Background: Vertical transmission of HIV remains one of the most common transmission modes. Antiretroviral therapy (ART) decreases the risk of transmission to less than 2%, but maintaining adherence to treatment remains a challenge. Some of the commonly reported barriers to adherence to ART include stress (physical and emotional), depression, and alcohol and drug abuse. Integrating screening and treatment for psychological problem such as depression was reported to improve adherence. In this study, we sought to determine the prevalence of depression and its association with adherence to ART among HIV-positive pregnant women attending antenatal care (ANC) clinics in Addis Ababa, Ethiopia., Methods: We conducted a cross-sectional survey from March through November 2018. Participants were conveniently sampled from 12 health institutions offering ANC services. We used the Patient Health Questionnaire-9 (PHQ-9) to screen for depression and the Center for Adherence Support Evaluation (CASE) Adherence index to evaluate adherence to ART. Descriptive statistics was used to estimate the prevalence of depression during third-trimester pregnancy and nonadherence to ART. A bivariate logistic regression analysis was used to get significant predictors for each of the two outcome measures. The final multivariable logistic regression analysis included variables with a P<0.25 in the bivariate logistic regression model; statistical significance was evaluated at P<0.05., Results: We approached 397 eligible individuals, of whom 368 (92.7%) participated and were included in the analysis. Of the total participants, 175(47.6%) had depression. The participants' overall level of adherence to ART was 82%. Pregnant women with low income were twice more likely to have depression (AOR = 2.10, 95%CI = 1.31-3.36). Women with WHO clinical Stage 1 disease were less likely to have depression than women with more advanced disease (AOR = 0.16, 95%CI = 0.05-0.48). There was a statistically significant association between depression and nonadherence to ART (P = 0.020); nonadherence was nearly two times higher among participants with depression (AOR = 1.88, 95%CI = 1.08-3.27)., Conclusion: We found a high prevalence of depression among HIV-positive pregnant women in the selected health facilities in Addis Ababa, and what was more concerning was its association with higher rates of nonadherence to ART adversely affecting the outcome of their HIV care. We recommend integrating screening for depression in routine ANC services., Competing Interests: The authors declare that they have no competing interest.
- Published
- 2022
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29. Efficacy and cost-effectiveness of task-shared care for people with severe mental disorders in Ethiopia (TaSCS): a single-blind, randomised, controlled, phase 3 non-inferiority trial.
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Hanlon C, Medhin G, Dewey ME, Prince M, Assefa E, Shibre T, Ejigu DA, Negussie H, Timothewos S, Schneider M, Thornicroft G, Wissow L, Susser E, Lund C, Fekadu A, and Alem A
- Subjects
- Adult, Aged, Cost-Benefit Analysis, Ethiopia, Female, Humans, Male, Middle Aged, Program Development, Rural Population, Single-Blind Method, World Health Organization, Mental Disorders economics, Mental Disorders therapy, Mental Health Services economics, Mental Health Services organization & administration, Outcome Assessment, Health Care
- Abstract
Background: There have been no trials of task-shared care (TSC) using WHO's mental health Gap Action Programme for people with severe mental disorders (psychosis or affective disorder) in low-income or middle-income countries. We aimed to evaluate the efficacy and cost-effectiveness of TSC compared with enhanced specialist mental health care in rural Ethiopia., Methods: In this single-blind, phase 3, randomised, controlled, non-inferiority trial, participants had a confirmed diagnosis of a severe mental disorder, recruited from either the community or a local outpatient psychiatric clinic. The intervention was TSC, delivered by supervised, non-physician primary health care workers trained in the mental health Gap Action Programme and working with community health workers. The active comparison group was outpatient psychiatric nurse care augmented with community lay workers (PSY). Our primary endpoint was whether TSC would be non-inferior to PSY at 12 months for the primary outcome of clinical symptom severity using the Brief Psychiatric Rating Scale, Expanded version (BPRS-E; non-inferiority margin of 6 points). Randomisation was stratified by health facility using random permuted blocks. Independent clinicians allocated groups using sealed envelopes with concealment and outcome assessors and investigators were masked. We analysed the primary outcome in the modified intention-to-treat group and safety in the per-protocol group. This trial is registered with ClinicalTrials.gov, number NCT02308956., Findings: We recruited participants between March 13, 2015 and May 21, 2016. We randomly assigned 329 participants (111 female and 218 male) who were aged 25-72 years and were predominantly of Gurage (198 [60%]), Silte (58 [18%]), and Mareko (53 [16%]) ethnicity. Five participants were found to be ineligible after randomisation, giving a modified intention-to-treat sample of 324. Of these, 12-month assessments were completed in 155 (98%) of 158 in the TSC group and in 158 (95%) of 166 in the PSY group. For the primary outcome, there was no evidence of inferiority of TSC compared with PSY. The mean BPRS-E score was 27·7 (SD 4·7) for TSC and 27·8 (SD 4·6) for PSY, with an adjusted mean difference of 0·06 (90% CI -0·80 to 0·89). Per-protocol analyses (n=291) were similar. There were 47 serious adverse events (18 in the TSC group, 29 in the PSY group), affecting 28 participants. These included 17 episodes of perpetrated violence and seven episodes of violent victimisation leading to injury, ten suicide attempts, six hospital admissions for physical health conditions, four psychiatric admissions, and three deaths (one in the TSC group, two in the PSY group). The incremental cost-effectiveness ratio for TSC indicated lower cost of -US$299·82 (95% CI -454·95 to -144·69) per unit increase in BPRS-E scores from a health care sector perspective at 12 months., Interpretation: WHO's mental health Gap Action Programme for people with severe mental disorders is as cost-effective as existing specialist models of care and can be implemented effectively and safely by supervised non-specialists in resource-poor settings., Funding: US National Institute of Mental Health., Competing Interests: Declaration of interests We declare no competing interests., (Copyright © 2022 Elsevier Ltd. All rights reserved.)
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- 2022
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30. Addressing the Consequences of the COVID-19 Lockdown for Children's Mental Health: Investing in School Mental Health Programs.
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Hamoda HM, Chiumento A, Alonge O, Hamdani SU, Saeed K, Wissow L, and Rahman A
- Subjects
- Child, Humans, School Mental Health Services economics, COVID-19 epidemiology, Mental Health statistics & numerical data, Pandemics, Physical Distancing, School Mental Health Services organization & administration, Schools organization & administration
- Abstract
Children are likely to struggle with mental health consequences relating to the COVID-19 pandemic. School closures and home confinement increase the risk for emotional distress, domestic violence and abuse, and social isolation, as well as for disruption of sleep-wake and meal cycles, physical exercise routines, and health care access. As schools reopen, school mental health programs (SMHPs) incorporating universal approaches will be important for all children, and targeted approaches will be necessary for those more severely affected. Using their experience in Pakistan, the authors provide a roadmap for extending the World Health Organization's eastern Mediterranean region's SMHP to address the mental health consequences of COVID-19 among children globally.
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- 2021
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31. Identifying challenges and recommendations for advancing global mental health implementation research: A key informant study of the National Institute of Mental Health Scale-Up Hubs.
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Naslund JA, Kalha J, Restivo JL, Amarreh I, Callands T, Chen H, Gomez-Restrepo C, Hamoda HM, Kapoor A, Levkoff S, Masiye J, Oquendo MA, Patel V, Petersen I, Sensoy Bahar O, Shields-Zeeman L, Ssewamala FM, Tugnawat D, Uribe-Restrepo JM, Vijayakumar L, Wagenaar BH, Wainberg ML, Wissow L, Wurie HR, Zimba C, and Pathare S
- Subjects
- Global Health, Humans, Mental Health, National Institute of Mental Health (U.S.), United States, Mental Disorders therapy, Mental Health Services
- Abstract
Objective: This study explored perspectives of researchers working with the National Institute of Mental Health (NIMH) Scale-Up Hubs, consisting of research partnerships for scaling up mental health interventions in low- and middle-income countries (LMICs), to: 1) identify common barriers to conducting impactful research on the implementation of evidence-based mental health services; and 2) provide recommendations to overcome these implementation challenges., Methods: A sequential qualitative approach was employed. First, an open-ended survey was distributed to the 10 Scale-Up Hubs and NIMH program staff asking informants to identify challenges in conducting mental health implementation research in LMICs. Second, survey findings guided an in-person workshop to generate implementation recommendations to inform the field., Results: In total, 46 respondents completed surveys, and 101 researchers attended the workshop. The workshop produced implementation recommendations for low-resource settings: 1) identifying impact of research on policy and practice; 2) sustaining careers of early researchers in global mental health; 3) engaging policymakers and donors to value mental health research; 4) supporting the workforce for delivering evidence-based treatments for mental disorders; and 5) promoting sustainability of programs., Conclusions: These findings can strengthen collaboration between researchers and key stakeholders, and highlight important targets for improving mental health implementation research in LMICs., (Copyright © 2021 Elsevier B.V. All rights reserved.)
- Published
- 2021
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32. Identifying pathways for large-scale implementation of a school-based mental health programme in the Eastern Mediterranean Region: a theory-driven approach.
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Alonge O, Chiumento A, Hamoda HM, Gaber E, Huma ZE, Abbasinejad M, Hosny W, Shakiba A, Minhas A, Saeed K, Wissow L, and Rahman A
- Subjects
- Adolescent, Child, Humans, Iran, Mediterranean Region, Pakistan, Mental Health, Schools
- Abstract
Globally there is a substantial burden of mental health problems among children and adolescents. Task-shifting/task-sharing mental health services to non-specialists, e.g. teachers in school settings, provide a unique opportunity for the implementation of mental health interventions at scale in low- and middle-income countries (LMICs). There is scant information to guide the large-scale implementation of school-based mental health programme in LMICs. This article describes pathways for large-scale implementation of a School Mental Health Program (SMHP) in the Eastern Mediterranean Region (EMR). A collaborative learning group (CLG) comprising stakeholders involved in implementing the SMHP including policymakers, programme managers and researchers from EMR countries was established. Participants in the CLG applied the theory of change (ToC) methodology to identify sets of preconditions, assumptions and hypothesized pathways for improving the mental health outcomes of school-aged children in public schools through implementation of the SMHP. The proposed pathways were then validated through multiple regional and national ToC workshops held between January 2017 and September 2019, as the SMHP was being rolled out in three EMR countries: Egypt, Pakistan and Iran. Preconditions, strategies and programmatic/contextual adaptations that apply across these three countries were drawn from qualitative narrative summaries of programme implementation processes and facilitated discussions during biannual CLG meetings. The ToC for large-scale implementation of the SMHP in the EMR suggests that identifying national champions, formulating dedicated cross-sectoral (including the health and education sector) implementation teams, sustained policy advocacy and stakeholders engagement across multiple levels, and effective co-ordination among education and health systems especially at the local level are among the critical factors for large-scale programme implementation. The pathways described in this paper are useful for facilitating effective implementation of the SMHP at scale and provide a theory-based framework for evaluating the SMHP and similar programmes in the EMR and other LMICs., (© The Author(s) 2020. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine.)
- Published
- 2020
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33. Correction to: Task sharing for the care of severe mental disorders in a low-income country (TaSCS): study protocol for a randomised, controlled, non-inferiority trial.
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Hanlon C, Alem A, Medhin G, Shibre T, Ejigu DA, Negussie H, Dewey M, Wissow L, Prince M, Susser E, Lund C, and Fekadu A
- Abstract
An amendment to this paper has been published and can be accessed via the original article.
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- 2020
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34. Erratum: Measuring functional disability in children with developmental disorders in low-resource settings: validation of Developmental Disorders-Children Disability Assessment Schedule (DD-CDAS) in rural Pakistan.
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Hamdani SU, Huma ZE, Wissow L, Rahman A, and Gladstone M
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[This corrects the article DOI: 10.1017/gmh.2020.10.]., (© The Author(s) 2020.)
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- 2020
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35. Measuring functional disability in children with developmental disorders in low-resource settings: validation of Developmental Disorders-Children Disability Assessment Schedule (DD-CDAS) in rural Pakistan.
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Hamdani SU, Huma ZE, Wissow L, Rahman A, and Gladstone M
- Abstract
Background: Developmental disorders (DDs) in children are a priority condition and guidelines have been developed for their management within low-resource community settings. However, a key obstacle is lack of open access, reliable and valid tools that lay health workers can use to evaluate the impact of such programmes on child outcomes. We adapted and validated the World Health Organization's Disability Assessment Schedule for children (WHODAS-Child), a lay health worker-administered functioning-related tool, for children with DDs in Pakistan., Methods: Lay health workers administered a version of the WHODAS-Child to parents of children with DDs ( N = 400) and without DDs ( N = 400), aged 2-12 years, after it was adapted using qualitative study. Factor analysis, validity, reliability and sensitivity to change analyses were conducted to evaluate the psychometric properties of the adapted outcome measure., Results: Among 800 children, 58% of children were male [mean (s.d.) age 6.68 (s.d. = 2.89)]. Confirmatory Factor Analysis showed a robust factor structure [χ
2 /df 2.86, RMSEA 0.068 (90% CI 0.064-0.073); Tucker-Lewis Index (TLI) 0.92; Comparative Fit Index (CFI) 0.93; Incremental Fit Index (IFI) 0.93]. The tool demonstrated high internal consistency ( α 0.82-0.94), test-retest [Intra-class Correlation Coefficient (ICC) 0.71-0.98] and inter-data collector (ICC 0.97-0.99) reliabilities; good criterion ( r -0.71), convergent ( r -0.35 to 0.71) and discriminative [M (s.d.) 52.00 (s.d. = 21.97) v . 2.14 (s.d. = 4.00); 95% CI -52.05 to -47.67] validities; and adequate sensitivity to change over time (ES 0.19-0.23)., Conclusions: The lay health worker administrated version of adapted WHODAS-Child is a reliable, valid and sensitive-to-change measure of functional disability in children aged 2-12 years with DDs in rural community settings of Pakistan., Competing Interests: The authors declare that they have no competing interests., (© The Author(s) 2020.)- Published
- 2020
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36. Primary Care Practitioner Training in Child and Adolescent Psychiatry (PTCAP): A Cluster-Randomized Trial.
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Espinet SD, Gotovac S, Knight S, Wissow L, Zwarenstein M, Lingard L, and Steele M
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- Adolescent, Child, Family, Humans, Primary Health Care, Referral and Consultation, Adolescent Psychiatry, Attention Deficit Disorder with Hyperactivity
- Abstract
Objectives: Rural primary care practitioners (PCPs) have a pivotal role to play in frontline pediatric mental health care, given limited options for referral and consultation. Yet they report a lack of adequate training and confidence to provide this care. The aim of this study was to test the effectiveness of the Practitioner Training in Child and Adolescent Psychiatry (PTCAP) program, which was designed to enhance PCPs' pediatric mental health care confidence. The program includes brief therapeutic skills and practice guidelines PCPs can use to address both subthreshold concerns and diagnosable conditions, themselves., Methods: The study design was a pilot, cluster-randomized, multicenter trial. Practices were randomly assigned to intervention ( n practices = 7; n PCPs = 42) or to wait-list control ( n practices = 6; n PCPs = 34). The intervention involved 8 hr of training in practice guidelines and brief therapeutic skills for depression, anxiety, attention deficit hyperactivity disorder, and behavioral disorders with case discussion and video examples, while the control practiced as usual. A linear random-effects model controlling for clustering and baseline was carried out on the individual-level data to examine between-group differences in the primary (i.e., confidence) and secondary (i.e., attitude and knowledge) outcomes at 1-week follow-up., Results: Findings were a statistically significant difference in the primary outcomes. Compared to the control group, the intervention group indicated significantly greater confidence in managing diagnosable conditions ( d = 1.81) and general concerns ( d = 1.73), as well as in making necessary referrals ( d = 1.27) and obtaining consults ( d = 0.74). While the intervention did not significantly impact secondary outcomes (attitudes and knowledge), regression analysis indicated that the intervention may have increased confidence, in part, by ameliorating the adverse impact of negative mental health care attitudes., Conclusion: PTCAP enhances PCPs' child/youth mental health care confidence in managing both general and diagnosable concerns. However, an 8-hr session focused on applying brief therapeutic skills was insufficient to significantly change attitudes and knowledge. Formal testing of PTCAP may be warranted, perhaps using more intensive training and including outcome assessments capable of determining whether increased PCP confidence translates to more effective management and better patient outcomes.
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- 2020
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37. The Mental Health Training Intervention for School Nurses and Other Health Providers in Schools.
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Bohnenkamp JH, Hoover SA, Connors EH, Wissow L, Bobo N, and Mazyck D
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- Adult, California, Female, Humans, Male, Maryland, Massachusetts, Michigan, Middle Aged, Minnesota, Health Personnel education, Inservice Training organization & administration, Mental Disorders nursing, Mental Health education, School Health Services organization & administration, School Nursing education
- Abstract
School nurses encounter many students presenting with mental health needs. However, school nurses report that they need additional training and resources to be able to support student mental health. This study involved a multilevel, stakeholder-driven process to refine the Mental Health Training Intervention for Health Providers in Schools (MH-TIPS), an in-service training and implementation support system for school health providers, including school nurses, to increase their competence in addressing student mental health concerns. Findings highlighted the importance of mental health content including assessment, common factors of positive therapeutic mental health interactions, common elements of evidence-based mental health practice, and resource and referral mapping. Additionally, multifaceted ongoing professional development processes were indicated. Study findings indicate that, with recommended modifications, the MH-TIPS holds promise as a feasible, useful intervention to support school nurse practice and ultimately impact student mental health and educational outcomes.
- Published
- 2019
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38. Implementation of Off-Site Integrated Care for Children: A Scoping Review.
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Spencer AE, Platt RE, Bettencourt AF, Serhal E, Burkey MD, Sikov J, Vidal C, Stratton J, Polk S, Jain S, and Wissow L
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- Child, Community Health Centers standards, Health Services Accessibility standards, Humans, Pediatrics standards, Referral and Consultation standards, Child Health Services standards, Child Welfare, Mental Health Services standards
- Abstract
Background: As an alternative to co-located integrated care, off-site integration (partnerships between primary care and non-embedded specialty mental health providers) can address the growing need for pediatric mental health services. Our goal is to review the existing literature on implementing off-site pediatric integrated care., Methods: We systematically searched the literature for peer-reviewed publications on off-site pediatric integrated care interventions. We included studies that involved systematic data collection and analysis, both qualitative and quantitative, of implementation outcomes (acceptability, adoption, appropriateness, feasibility, fidelity, implementation cost, penetration, and sustainability)., Results: We found 39 original articles from 24 off-site programs with a variety of study designs, most with secondary implementation outcomes. Models of off-site integration varied primarily along two dimensions: direct vs. indirect, and in-person vs. remote. Overall, off-site models were acceptable to providers, particularly when the following were present: strong interdisciplinary communication, timely availability and reliability of services, additional support beyond one-time consultation, and standardized care algorithms. Adoption and penetration were facilitated by enhanced program visibility, including on-site champions. Certain clinical populations (e.g., school-age, less complicated ADHD) seemed more amenable to off-site integrated models than others (e.g., preschool-age, conduct disorders). Lack of funding and inadequate reimbursement limited sustainability in all models., Conclusions: Off-site interventions are feasible, acceptable, and often adopted widely with adequate planning, administrative support, and interprofessional communication. Studies that focus primarily on implementation and that consider the perspectives of specialty providers and patients are needed.
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- 2019
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39. Collaborative care for child and youth mental health problems in a middle-income country: study protocol for a randomized controlled trial training general practitioners.
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Sharifi V, Shahrivar Z, Zarafshan H, Ashkezary SB, Stuart E, Mojtabai R, and Wissow L
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- Adolescent, Adolescent Behavior, Age Factors, Attitude of Health Personnel, Child, Child Behavior, Female, General Practitioners psychology, Health Knowledge, Attitudes, Practice, Humans, Interdisciplinary Communication, Iran, Male, Mental Disorders diagnosis, Mental Disorders psychology, Randomized Controlled Trials as Topic, Time Factors, Treatment Outcome, Adolescent Health Services organization & administration, Child Health Services organization & administration, Community Mental Health Services organization & administration, Delivery of Health Care, Integrated organization & administration, General Practitioners education, Mental Disorders therapy, Patient Care Team organization & administration
- Abstract
Background: Child and youth mental health problems are leading causes of disability and particular problems in low- and middle-income countries where populations are young and child mental health services are in short supply. Collaborative care models that support primary care providers' efforts to detect and treat child mental health problems offer one way to address this need. However, collaborative care for child mental health can be more complex than collaboration for adults for a number of reasons, including two-generational aspects of care, high degrees of co-morbidity, and variations in presentation across developmental stages., Methods: The study takes advantage of an existing collaborative care network in Tehran, Iran, in which general practitioners are supported by community mental health centers to care for adult mental health problems. At present, those practitioners are asked to refer children with mental health problems to the collaborating centers rather than treating them themselves. We are conducting a cluster randomized trial in which practitioners in the network will be randomized to receive training in child/youth mental health treatment or a booster training on recognition and referral. Children/youth aged 5-15 years making visits to the practitioners will be screened using the Strengths and Difficulties Questionnaire; those found positive will be followed for six months to compare outcomes between those treated by trained or control practitioners., Discussion: If the trial demonstrates superior outcomes among children treated by trained practitioners, it will support the feasibility of expanding collaborative care networks to include children., Trial Registration: ClinicalTrials.gov, NCT03144739 . Registered on 8 May 2017.
- Published
- 2019
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40. The study of effect moderation in youth suicide-prevention studies.
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Musci RJ, Kharrazi H, Wilson RF, Susukida R, Gharghabi F, Zhang A, Wissow L, Robinson KA, and Wilcox HC
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- Adolescent, Adult, Female, Humans, Male, United States, Young Adult, Primary Prevention methods, Program Evaluation, Suicide, Attempted prevention & control
- Abstract
Purpose: Suicide is now the second leading cause of death among persons between the ages of adolescents and emerging adults and rates have increased despite more funding and broader implementation of youth suicide-prevention programs. A systematic review was conducted focusing on identifying youth suicide-prevention studies within the United States. This paper reports on the methods utilized for understanding possible moderators of suicide-prevention program outcomes., Methods: We searched six databases from 1990 through August 2017 to identify studies of suicide-preventive interventions among those under age 26 years. Two independent team members screened search results and sequentially extracted information related to statistical methods of moderation analyses., Results: 69 articles were included in the systematic review of which only 17 (24.6%) explored treatment effect heterogeneity using moderation analysis. The most commonly used analytic tool was regression with an interaction term. The moderators studied included demographic characteristics such as gender and ethnicity as well as individual characteristics such as traumatic stress exposure and multiple prior suicide attempts., Conclusions: With a greater emphasis from the federal government and funding agencies on precision prevention, understanding which prevention programs work for specific subgroups is essential. Only a small percentage of the reviewed articles assessed moderation effects. This is a substantial research gap driven by sample size or other limitations which have impeded the identification of intervention effect heterogeneity.
- Published
- 2018
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41. When Behavioral Health Concerns Present in Pediatric Primary Care: Factors Influencing Provider Decision-Making.
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Connors EH, Arora P, Blizzard AM, Bower K, Coble K, Harrison J, Pruitt D, Steinberg J, and Wissow L
- Subjects
- Adolescent, Attitude of Health Personnel, Child, Female, Humans, Interviews as Topic, Male, Maryland, Mental Disorders diagnosis, Mental Disorders therapy, Nurses psychology, Pediatric Nurse Practitioners psychology, Pediatricians psychology, Physicians, Primary Care, Practice Patterns, Physicians', Rural Health Services, Urban Health Services, Decision Making, Health Knowledge, Attitudes, Practice, Health Personnel psychology, Mental Disorders psychology, Pediatrics methods, Primary Health Care methods, Referral and Consultation
- Abstract
Primary care providers (PCPs) frequently encounter behavioral health (BH) needs among their pediatric patients. However, PCPs report variable training in and comfort with BH, and questions remain about how and when PCPs address pediatric BH needs. Existing literature on PCP decisions to address pediatric BH in-office versus referring to subspecialty BH is limited and findings are mixed. Accordingly, this study sought to examine parameters and contextual factors influencing PCP decisions and practices related to BH care. Qualitative interview results with 21 PCPs in Maryland indicated that decisions about how and when to address pediatric BH concerns are influenced by the type BH service needed, patient characteristics, the availability of BH services in the community, and possibly PCPs' perceptions of BH care as a distinct subspecialty. Findings suggest that efforts to support individual PCPs' capacity to address BH within primary care must be balanced by efforts to expand the subspecialty BH workforce.
- Published
- 2018
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42. Correlates of Patterns of Health Values of African Americans Living With HIV/AIDS: Implications for Advance Care Planning and HIV Palliative Care.
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Mitchell MM, Hansen ED, Tseng TY, Shen M, Rushton C, Smith T, Hutton N, Wolfe J, Bone L, Keruly J, Wissow L, Catanzarite Z, and Knowlton AR
- Subjects
- Adult, Advance Care Planning, Aged, Female, HIV Infections therapy, Health Status, Humans, Male, Middle Aged, Palliative Care psychology, Substance-Related Disorders ethnology, Substance-Related Disorders psychology, Terminal Care psychology, Young Adult, Black or African American psychology, HIV Infections ethnology, HIV Infections psychology, Health Knowledge, Attitudes, Practice ethnology
- Abstract
Context: Advance care planning rates remain low, especially among people who are HIV positive, disadvantaged, and African American. Although advance care planning can be a sensitive topic for clinicians and patients to discuss, health values clarification can be an important initial step., Objectives: The purpose of the study was to explore health values of African Americans living with HIV/AIDS and to examine correlates of these values., Methods: Data were from the first 325 participants in the AFFIRM Care study, which enrolled adults living with HIV/AIDS in Baltimore, Maryland, who had histories of illicit drug use. Respondents were asked whether (yes/no) they thought any of six health states would be worse than death: severe unremitting pain, total dependency on others, irreversible coma, being on mechanical ventilation, nursing home residence, and severe dementia. Latent class analysis was used to group individuals by their pattern of responses, interpretable as preference for aggressive (life-sustaining) or nonaggressive (palliative) end-of-life care. Latent class regression analysis was used to examine associations between class membership and background, health status, and social variables., Results: We found statistical support for a three-class latent class analysis model: 1) the nonaggressive treatment class, comprising 43% of cases, in which members perceived that every state was worse than death; 2) the aggressive treatment class, comprising 33% of cases, in which members perceived that none of the states was worse than death; and 3) the mixed class (24% of cases), in which members perceived that only four of the six states were worse than death., Conclusion: Three-quarters of participant response patterns had clear preferences for treatment decisions. Further research is needed to ensure inclusion of end-of-life scenarios relevant to this population., (Copyright © 2018 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.)
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- 2018
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43. RCT of an integrated CBT-HIV intervention on depressive symptoms and HIV risk.
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Tobin K, Davey-Rothwell MA, Nonyane BAS, Knowlton A, Wissow L, and Latkin CA
- Subjects
- Adolescent, Adult, Condoms, Female, HIV Infections prevention & control, Humans, Male, Middle Aged, Risk Factors, Sexual Behavior, Substance Abuse, Intravenous, Young Adult, Cognitive Behavioral Therapy, Depression therapy, HIV Infections psychology
- Abstract
Depression and depressive symptoms mediate the association between drug use and HIV risk. Yet, there are few interventions that target depressive symptoms and HIV risk for people who use drugs (PWUD). This study was a randomized controlled trial of an integrated cognitive behavioral therapy and HIV prevention intervention to reduce depressive symptoms, injection risk behaviors and increase condom use in a sample of urban people who used heroin or cocaine in the prior 6 months. A total of 315 individuals aged 18-55, who self-reported at least one HIV drug and sex risk behavior and scored ≥16 and <40 on the Centers for Epidemiologic Studies-Depression (CES-D) scale were randomized using a two-block design, stratified by sex to ensure equivalent numbers, to a 10 session intervention arm (n = 162) or a single session control arm (n = 153). The outcomes of interest were decreases in CES-D score and injection risk behaviors and increases in condom use. The sample was majority African American (85%) and unemployed (94%). Nearly half (47%) reported injection in the prior 6 months and only 19% were taking medication for depression. Follow-up assessments were conducted at 6 and 12 months. Retention at 12 months was 94%. Intervention arm was associated with statistically significantly lower CES-D score at 12 month compared to control. No differences were observed between arms in injection risk. At 6 month, intervention was associated with greater odds of condom use with non-main partner. These findings suggest the potential role of the integrated intervention in reducing depressive symptoms, but weak impact on HIV risk. This trial is registered with ClinicalTrials.gov under the title "Neighborhoods, Networks, Depression, and HIV Risk" number NCT01380613.
- Published
- 2017
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44. Surveillance or Engagement: Children's Conflicts During Health Maintenance Visits.
- Author
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Polk S, Horwitz R, Longway S, Bonilla A, Fothergill K, Karver M, Salmon P, and Wissow L
- Subjects
- Black or African American psychology, Child, Comprehension, Female, Hispanic or Latino psychology, Humans, Interviews as Topic, Male, Medicaid, Parents, Pediatrics, United States, Video Recording, White People psychology, Attitude to Health ethnology, Child Health ethnology, Communication, Physician-Patient Relations
- Abstract
Objective: School-aged health maintenance visits seek to prevent or intervene early with health issues of lifelong importance. Little is known about what children expect to happen in these visits or how they experience them, factors related to their engagement as active collaborators in care., Methods: Thirty children (53% Latino, 27% African-American, and 20% white) ages 7 to 11 years were video recorded during a health maintenance visit and then interviewed while reviewing the videos. Interview transcripts were analyzed for understanding the purpose of the visit, feelings of comfort and discomfort, and decisions about how much to participate., Results: Children expected doctors to be helpful, caring, and a source of important information. They anticipated visits to include immunizations, a physical examination, and praise for accomplishments, but could be surprised by questions about behavior, family function, and lifestyle. During visits, feelings varied from warmth toward providers to embarrassment, wariness, irritation, and boredom. Even when bored or irritated, children hesitated to interrupt parent-provider conversations or correct perceived provider misunderstandings, not wanting to be seen as inappropriate or rude. When asked questions they considered off topic, likely to reveal sensitive information, or that could lead to changes in their lifestyle, some were silent or answered evasively. Some said they would have spoken more freely without their parent present but valued parental support and wanted parents to make important decisions., Conclusions: School-aged children's limited knowledge of what to expect in health maintenance visits, uncertainty about conversational norms with adults, and desire to assert control over their lives compete with their desire to access expert advice and form bonds with providers. Engaging children in health maintenance visits might require more relationship-building and education about the visit's goals., (Copyright © 2017 Academic Pediatric Association. All rights reserved.)
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- 2017
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45. Pediatric Primary Care Providers' Use of Behavioral Health Consultation.
- Author
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Arora PG, Connors EH, Coble K, Blizzard A, Wissow L, and Pruitt D
- Subjects
- Child, Humans, Interviews as Topic, Organizational Culture, Qualitative Research, Attitude of Health Personnel, Health Behavior, Pediatrics, Primary Health Care organization & administration, Referral and Consultation
- Abstract
This column describes a qualitative study in which 32 primary care providers (PCPs) reported barriers to and facilitators of using a behavioral health (BH) consultation program. Barriers included program incompatibility with organizational culture, limited exposure to the program, existing access to referral sources, and negative beliefs about BH consultation. Reported facilitators included having personal relationships with BH program staff, exposure to program information, and positive beliefs about BH consultation. PCPs recommended outreach activities and optimal program features to increase use of BH consultation.
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- 2017
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46. Data Linkage Strategies to Advance Youth Suicide Prevention: A Systematic Review for a National Institutes of Health Pathways to Prevention Workshop.
- Author
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Wilcox HC, Kharrazi H, Wilson RF, Musci RJ, Susukida R, Gharghabi F, Zhang A, Wissow L, and Robinson KA
- Subjects
- Adolescent, Humans, Suicidal Ideation, Suicide, Attempted prevention & control, Suicide, Attempted statistics & numerical data, United States epidemiology, Young Adult, Information Storage and Retrieval, Suicide statistics & numerical data, Suicide Prevention
- Abstract
Background: Linking national, state, and community data systems to data from prevention programs could allow for longer-term assessment of outcomes and evaluation of interventions to prevent suicide., Purpose: To identify and describe data systems that can be linked to data from prevention studies to advance youth suicide prevention research., Data Sources: A systematic review, an environmental scan, and a targeted search were conducted to identify prevention studies and potentially linkable external data systems with suicide outcomes from January 1990 through December 2015., Study Selection: Studies and data systems had to be U.S.-based and include persons aged 25 years or younger. Data systems also had to include data on suicide, suicide attempt, or suicidal ideation., Data Extraction: Information about participants, intervention type, suicide outcomes, primary analytic method used for linkage, statistical approach, analyses performed, and characteristics of data systems was abstracted by 2 reviewers., Data Synthesis: Of 47 studies (described in 59 articles) identified in the systematic review, only 6 were already linked to data systems. A total of 153 unique and potentially linkable data systems were identified, but only 66 were classified as "fairly accessible" and had data dictionaries available. Of the data systems identified, 19% were established primarily for research, 11% for clinical care or operations, 29% for administrative services (such as billing), and 52% for surveillance. About one third (37%) provided national data, 12% provided regional data, 63% provided state data, and 41% provided data below the state level (some provided coverage for >1 geographic unit)., Limitation: Only U.S.-based studies published in English were included., Conclusion: There is untapped potential to evaluate and enhance suicide prevention efforts by linking suicide prevention data with existing data systems. However, sparse availability of data dictionaries and lack of adherence to standard data elements limit this potential., Primary Funding Source: Agency for Healthcare Research and Quality.
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- 2016
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47. Psychosocial interventions for use in pediatric primary care: An examination of providers' perspectives.
- Author
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Arora PG, Stephan SH, Becker KD, and Wissow L
- Subjects
- Adult, Female, Health Services Accessibility standards, Humans, Male, Middle Aged, Nurse Practitioners psychology, Psychometrics instrumentation, Psychometrics methods, Surveys and Questionnaires, Pediatrics methods, Perception, Physicians, Primary Care psychology, Practice Patterns, Physicians' trends, Primary Health Care methods
- Abstract
Introduction: The integration of psychosocial interventions in primary care settings is 1 mechanism to increase access to mental health care to youth in need. Although the delivery of psychosocial interventions by primary care providers (PCPs) reflects 1 example of this integration, research indicates that various barriers to implementation by PCPs exist. With the goal of informing a framework to guide the selection of treatments amenable to PCP practice, the authors sought to examine which criteria might influence a PCP's intention to use a given psychosocial intervention., Method: Using survey methodology, 49 PCPs ranked characteristics of interventions for feasibility and applicability to their patient populations and setting., Results: Survey respondents found the following characteristics most important: time to employ, applicability to multiple disorders, ease of use, and ease of learning. Providers who endorsed more negative beliefs and attitudes toward addressing psychosocial concerns in youth were more likely to see certain criteria, such as ease of use and ease of learning, as more important., Discussion: The authors illustrate the potential application of these findings to the selection of psychosocial interventions for use in primary care and discuss future research directions. (PsycINFO Database Record, ((c) 2016 APA, all rights reserved).)
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- 2016
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48. Child and Adolescent Mental Health Care in Iran: Current Status and Future Directions.
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Sharifi V, Mojtabai R, Shahrivar Z, Alaghband-Rad J, Zarafshan H, and Wissow L
- Subjects
- Adolescent, Child, Family, Female, Health Policy, Health Services Accessibility trends, Humans, Iran epidemiology, Male, Mental Health Services statistics & numerical data, Prevalence, Primary Health Care, Workforce, Adolescent Health Services statistics & numerical data, Child Health Services statistics & numerical data, Health Services Needs and Demand trends, Mental Disorders epidemiology, Mental Health Services organization & administration
- Abstract
Background: The need for mental health care among children and adolescents in Iran, as in other low and middle income countries (LAMIC) remains mostly unmet. In this paper, we sought to provide an overview of the extent of unmet need and mental health services in Iran. We also aimed to propose approaches to address this gap., Method: We reviewed the published epidemiologic studies of child and adolescent mental and behavioral health problems in Iran. We also examined the current status of child mental health services and the gaps between current needs and available services based on published literature that included papers published in scientific journals, as well as governmental and other administrative reports. The contextual issues relevant to child mental health care were also explored, as well as the possibilities to introduce new or scale up promising services., Results: Child and adolescent mental and behavioral health problems are highly prevalent in Iran. Different studies have estimated that 16.7% to 36.4% of children and adolescents suffer from one or more mental health problems. However, there is a serious scarcity of resources to meet this need. Available services are delivered by independent public organizations (e.g., Ministry of Health, Welfare Organization, and Ministry of Education) or private sector with inefficient communication and collaboration among them and no mandatory national mental health policy. Available specialized child and adolescent services are mostly confined to small inpatient units and university outpatient facilities in larger cities, and there is a scarce evidence for the effectiveness of the available services., Conclusions: Expansion of primary care's role in timely detection and management of child and adolescent mental health problems, implementation of task-shifting and -sharing initiatives, as well as improved collaboration among responsible governmental and non-governmental sectors are some of the most promising future venues to improve mental health care for the Iranian youth.
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- 2016
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49. Data Linkage Strategies to Advance Youth Suicide Prevention.
- Author
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Wilcox HC, Wissow L, Kharrazi H, Wilson RF, Musci RJ, Zhang A, and Robinson KA
- Subjects
- Humans, Data Systems, Gray Literature statistics & numerical data, United States, Child, Adolescent, Young Adult, Adult, Information Storage and Retrieval, Suicide statistics & numerical data, Suicide Prevention
- Abstract
Objectives: Linking national, State, and community data systems, such as those used for medical service billing, to existing data from suicide prevention efforts could facilitate the assessment of longer term outcomes. Our objective was to identify and describe data systems that can be linked to data from studies of youth suicide prevention interventions and to identify analytic approaches to advance youth suicide prevention research., Data Sources: We conducted a systematic review to identify studies of suicide prevention interventions and three types of searches to identify data systems providing suicide-related outcomes: (1) a literature search, (2) an environmental scan of gray literature, and (3) a targeted search, through contact with relevant individuals, in six States, two cities, and one tribal community., Review Methods: Two independent reviewers screened all results. Studies and data systems had to be based in the United States; include individuals between 0 and 25 years of age; and include suicide, suicide attempt, or suicide ideation as an outcome., Results: Of the 47 studies (described in 59 articles) of suicide prevention interventions identified in our systematic review, only 6 studied outcomes by linking to external data systems and only 12 explored treatment heterogeneity through the effects of moderators such as gender or race/ethnicity. We identified 153 unique and potentially linkable external data systems, 66 of which we classified as "fairly accessible" with data dictionaries available., Conclusions: There is potential for linking existing data systems with suicide prevention efforts to assess the broader and extended impact of suicide prevention interventions. However, sparse availability of data dictionaries and lack of adherence to standard data elements limit the potential utility of linking prevention efforts with data systems., Competing Interests: None of the investigators have any affiliations or financial involvement that conflicts with the material presented in this report., (This publication is in the public domain.)
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- 2016
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50. Pediatric Use of Emergency Medical Services: The Role of Chronic Illnesses and Behavioral Health Problems.
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Knowlton AR, Weir B, Fields J, Cochran G, McWilliams J, Wissow L, and Lawner BJ
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- Adolescent, Baltimore, Child, Child, Preschool, Female, Humans, Infant, Male, Medical Audit, Retrospective Studies, Young Adult, Child Behavior, Chronic Disease, Emergency Medical Services statistics & numerical data
- Abstract
Objective: The increasing use of prehospital emergency medical services (EMS) and its contribution to rising emergency department use and healthcare costs point to the need for better understanding factors associated with EMS use to inform preventive interventions. Understanding patient factors associated with pediatric use of EMS will inform pediatric-specific intervention. We examined pediatric patient demographic and health factors associated with one-time and repeat use of EMS., Methods: We reviewed data from Baltimore City Fire Department EMS patient records over a 23-month period (2008-10) for patients under 21 years of age (n = 24,760). Repeat use was defined as involvement in more than one EMS incident during the observation period. Analyses compared demographics of EMS users to the city population and demographics and health problems of repeat and one-time EMS users. Health comparisons were conducted at the patient and incident levels of analysis., Results: Repeat users (n = 1,931) accounted for 9.0% of pediatric users and 20.8% of pediatric incidents, and were over-represented among the 18-20 year age group and among females. While trauma accounted for approximately one-quarter of incidents, repeat versus one-time users had a lower proportion of trauma-related incidents (7.2% vs. 26.7%) and higher proportion of medical-related incidents (92.6% vs. 71.4%), including higher proportions of incidents related to asthma, seizures, and obstetric/gynecologic issues. In patient-level analysis, based on provider or patient reports, greater proportions of repeat compared to one-time users had asthma, behavioral health problems (mental, conduct and substance use problems), seizures, and diabetes., Conclusions: Chronic somatic conditions and behavioral health problems appear to contribute to a large proportion of the repeat pediatric use of this EMS system. Interventions may be needed to engage repeat users in primary care and behavioral health services, to train EMS providers on the recognition and management of behavioral health emergencies, and to improve family care and self-management of pediatric asthma and other chronic conditions.
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- 2016
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