412 results on '"Withers, Dominic J"'
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2. Inhibition of IL-11 signalling extends mammalian healthspan and lifespan
3. Protein restriction during pregnancy alters Cdkn1c silencing, dopamine circuitry and offspring behaviour without changing expression of key neuronal marker genes
4. Detection of senescence using machine learning algorithms based on nuclear features
5. Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity
6. COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells
7. Sub-Chronic Ketamine Administration Increases Dopamine Synthesis Capacity in the Mouse Midbrain: a Preclinical In Vivo PET Study
8. Correction: Sub-Chronic Ketamine Administration Increases Dopamine Synthesis Capacity in the Mouse Midbrain: a Preclinical In Vivo PET Study
9. Spontaneous Cholemia in C57BL/6 Mice Predisposes to Liver Cancer in NASH
10. Muscle 4EBP1 activation modifies the structure and function of the neuromuscular junction in mice
11. Reproducing the dopamine pathophysiology of schizophrenia and approaches to ameliorate it: a translational imaging study with ketamine
12. Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis
13. Extrahypothalamic GABAergic nociceptin-expressing neurons regulate AgRP neuron activity to control feeding behavior
14. Deletion of myeloid IRS2 enhances adipose tissue sympathetic nerve function and limits obesity
15. Evaluation of Intraperitoneal [ 18 F]-FDOPA Administration for Micro-PET Imaging in Mice and Assessment of the Effect of Subchronic Ketamine Dosing on Dopamine Synthesis Capacity.
16. Ribosomal S6 kinase 1 regulates ‘inflammaging’ via the senescence secretome
17. Neuronatin deletion causes postnatal growth restriction and adult obesity in 129S2/Sv mice
18. Cardiac glycosides are broad-spectrum senolytics
19. Genomic imprinting and its effects on postnatal growth and adult metabolism
20. Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
21. Author Correction: Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
22. Longer Lifespan, Altered Metabolism, and Stress Resistance in Drosophila from Ablation of Cells Making Insulin-Like Ligands
23. Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production
24. Neuronatin regulates pancreatic [beta] cell insulin content and secretion
25. Activation of eIF4E-binding-protein-1 rescues mTORC1-induced sarcopenia by expanding lysosomal degradation capacity
26. Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function
27. Genetic deletion of S6k1 does not rescue the phenotypic deficits observed in the R6/2 mouse model of Huntington’s disease
28. Reduced insulin signaling in neurons induces sex-specific health benefits
29. Differential CpG methylation atNnatin the early establishment of beta cell heterogeneity
30. Phosphoinositide Signalling Pathways in Metabolic Regulation
31. Activation of eIF4E ‐binding‐protein‐1 rescues mTORC1 ‐induced sarcopenia by expanding lysosomal degradation capacity
32. RF13 | PMON143 BRF1-Mediated Paracrine Signalling by a Subset of SOX2-Expressing Stem Cells is Required for Normal Development of the Stem Cell Compartment and Terminal Differentiation of Pituitary Committed Progenitors
33. Evaluation of Intraperitoneal [18F]-FDOPA Administration for Micro-PET Imaging in Mice and Assessment of the Effect of Subchronic Ketamine Dosing on Dopamine Synthesis Capacity
34. Reduced insulin signalling in neurons induces sex-specific health benefits
35. Peripheral activation of the Y2-receptor promotes secretion of GLP-1 and improves glucose tolerance
36. PHYSIOLOGY: An atypical switch for metabolism and ageing
37. Mammalian models of extended healthy lifespan
38. Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span
39. Differential Effects of Laparoscopic Sleeve Gastrectomy and Laparoscopic Gastric Bypass on Appetite, Circulating Acyl-ghrelin, Peptide YY3-36 and Active GLP-1 Levels in Non-diabetic Humans
40. AGEING: Out with the old
41. β-synuclein potentiates synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death in the absence of other synucleins
42. Dominant Role of the p110β Isoform of PI3K over p110α in Energy Homeostasis Regulation by POMC and AgRP Neurons
43. Evaluation of Intraperitoneal [ 18 F]-FDOPA Administration for Micro-PET Imaging in Mice and Assessment of the Effect of Subchronic Ketamine Dosing on Dopamine Synthesis Capacity.
44. A link between FTO, ghrelin, and impaired brain food-cue responsivity
45. Longevity of insulin receptor substrate1 null mice is not associated with increased basal antioxidant protection or reduced oxidative damage
46. Long‐term p110α PI3K inactivation exerts a beneficial effect on metabolism
47. Fibroblasts derived from long-lived insulin receptor substrate 1 null mice are not resistant to multiple forms of stress
48. Caloric restriction reveals a metabolomic and lipidomic signature in liver of male mice
49. Deletion of the von Hippel--Lindau gene in pancreatic [beta] cells impairs glucose homeostasis in mice
50. Reproducing the dopamine pathophysiology of schizophrenia and approaches to ameliorate it
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