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418 results on '"Wittert, G. A."'

3. Associations of OSA and Nocturnal Hypoxemia with Strength and Body Composition in Community Dwelling Middle Aged and Older Men

Author

Stevens D, Appleton S, Vincent AD, Melaku Y, Martin S, Gill T, Hill C, Vakulin A, Adams R, and Wittert G

Subjects
grip strength, muscle mass, intermittent hypoxemia, myosteatosis, Psychiatry, RC435-571, Neurophysiology and neuropsychology, QP351-495
Abstract

David Stevens,1 Sarah Appleton,1– 3 Andrew D Vincent,4,5 Yohannes Melaku,1 Sean Martin,3,4 Tiffany Gill,4 Catherine Hill,4,6 Andrew Vakulin,1,7 Robert Adams,1,2,8 Gary Wittert2,3,5 1Adelaide Institute for Sleep Health, College of Medicine and Public Health, Flinders University, Adelaide, SA, Australia; 2The Health Observatory, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia; 3Freemason Foundation Centre for Men’s Health, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia; 4Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia; 5Centre of Nutrition and Gastrointestinal Diseases, Nutrition Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia; 6Rheumatology Unit, The Queen Elizabeth Hospital and the Royal Adelaide Hospital, Central Adelaide Local Health Network, Adelaide, SA, Australia; 7Sleep and Circadian Research Group, Woolcock Institute of Medical Research, University of Sydney, Sydney, NSW, Australia; 8Respiratory and Sleep Services, Southern Adelaide Local Health Network, Adelaide, SA, AustraliaCorrespondence: David StevensAdelaide Institute for Sleep Health, College of Medicine and Public Health, Flinders University, Level 2a, 5 Laffer Drive, Bedford Park, Adelaide, SA 5042, AustraliaTel +61 8 7221 8306Email david.stevens@flinders.edu.auPurpose: Reduced hand grip strength (HGS) is associated with poorer health in chronic conditions, yet there has been little research examining the association with hand grip strength and obstructive sleep apnea (OSA). Further, these studies have not examined, nor adjusted, for muscle mass. The aim of this study was to determine associations between OSA indices, HGS, muscle mass, and fat mass.Participants and Methods: A total of 613 participants (age range 41– 88, BMI 28.6 ± 4.3) from the population-based Men Androgen Inflammation Lifestyle Environment and Stress Study underwent in-home overnight polysomnography, assessment of dominant and non-dominant HGS, and dual x-ray absorptiometry to determine whole body muscle mass and fat mass. Linear models determined cross-sectional associations of polysomnographic-derived OSA indices with hand grip strength, muscle mass, and fat mass, whilst adjusting for lifestyle information (income, smoking status, diet, self-reported physical activity), blood sample derived testosterone and systemic inflammation (C-reactive protein), cardiometabolic health (cardiovascular disease, hypertension, type 2 diabetes), and depression.Results: In adjusted models, reduced dominant HGS was associated with lower oxygen nadir (unstandardised β [B] = 0.19, 95% confidence interval [CI] 0.08 to 0.29), greater time spent below 90% oxygen saturation (B = − 0.08, 95% CI − 0.14 to − 0.02), and increased apnea duration (B = − 0.3, 95% CI − 0.23 to − 0.02). By contrast, there were no associations between HGS and both AHI and REM AHI. Fat mass was consistently associated with worsening OSA indices, whereas muscle mass demonstrated no associations with any OSA index.Conclusion: Our findings suggest impairments in HGS may be related to fat infiltration of muscle, hypoxemia-induced reductions in peripheral neural innervation, or even endothelial dysfunction, which is a common outcome of hypoxemia. Longitudinal data are needed to further examine these hypotheses and establish if reduced grip strength in patients with OSA is associated with long-term adverse health outcomes.Keywords: grip strength, muscle mass, intermittent hypoxemia, myosteatosis

Published
2020

7. O003 Longitudinal associations of obstructive sleep apnea and sleep macroarchitecture with future cognitive function in middle-aged and older men from a community-based cohort study

Author

Parker, J, primary, Vakulin, A, additional, Melaku, Y, additional, Wittert, G, additional, Martin, S, additional, D'Rozario, A, additional, Catcheside, P, additional, Lechat, B, additional, Teare, A, additional, Toson, B, additional, Appleton, S, additional, and Adams, R, additional

Published
2022
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19. The effect of antenatal lifestyle advice for women who are overweight or obese on secondary measures of neonatal body composition: the LIMIT randomised trial

Author

Dodd, J M, Deussen, A R, Mohamad, I, Rifas-Shiman, S L, Yelland, L N, Louise, J, McPhee, A J, Grivell, R M, Owens, J A, Gillman, M W, Robinson, J S, Turnbull, D, Crowther, C, Wittert, G, Moran, L, Cramp, C, ewman, A, Kannieappian, L, Hendrijanto, S, Kelsey, M, Beaumont, J, Danz, C, Koch, J, Webber, A, Holst, C, Zhang, S, Ball, V, Ball, K, Salehi, N, Bartley, R, Stafford-Green, R, Ophel, S, Cooney, M, Szmeja, M, hort, A, Melrose, A, Han, S, Chapple, L, Svigos, J, Bhatia, V, Manton, N, McGavigan, J, Bryce, R, Coppi, S, Fanning, C, Hannah, G, Ignacio, M, Pollard, H, Schmidt, F, Shinners, Y, Dekker, G, Kennedy-Andrews, S, Beaven, R, Niven, J, Burgen, S, Dalton, J, Dewhurst, N, Forst, L, Mugg, V, Will, C, Stone, H, Wilkinson, C, Purcell, H, Wood, J, Press, D, Ralph, K, Donleavy, S, Seager, S, Gately, F, Jolly, A, Lahnstein, L, Harding, S, Daw, K, Hedges, M, and Fraser-Trumble, R

Published
2016
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20. Antenatal dietary and lifestyle advice for women who are overweight or obese and the effect on fetal growth and adiposity: the LIMIT randomised trial

Author

Grivell, R M, Yelland, L N, Deussen, A, Crowther, C A, Dodd, J M, Turnbull, D, McPhee, A, Gillman, M, Wittert, G, Owens, J A, Robinson, J S, Moran, L, Cramp, C, Newman, A, Kannieappan, L, Hendrijanto, S, Kelsey, M, Beaumont, J, Danz, C, Koch, J, Webber, A, Holst, C, Robinson, K, Zhang, S, Ball, V, Ball, K, Deussen, H, Salehi, N, Bartley, R, Stafford-Green, R, Ophel, S, Cooney, M, Szmeja, M, Short, A, Melrose, A, Han, S, Mohamad, I, Chapple, L, Earl, R, Staehr, C, Parange, N, Barreto, M, McGavigan, J, Bryce, R, Coppi, S, Fanning, C, Hannah, G, Ignacio, M, Pollard, H, Schmidt, F, Shinners, Y, Dekker, G, Kennedy-Andrews, S, Beaven, R, Niven, J, Burgen, S, Dalton, J, Dewhurst, N, Forst, L, Mugg, V, Will, C, Stone, H, Wilkinson, C, Purcell, H, Wood, J, Press, D, Ralph, K, Donleavy, S, Seager, S, Gately, F, Jolly, A, Lahnstein, L, Harding, S, Daw, K, Hedges, M, and Fraser-Trumble, R

Published
2016
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26. Men's sexual help-seeking and care needs after radical prostatectomy or other non-hormonal, active prostate cancer treatments

Author

Hyde MK, Opozda M, Laurie K, Vincent AD, Oliffe JL, Nelson CJ, Dunn J, Chung E, Gillman M, Manecksha RP, Wittert G, and Chambers SK

Subjects
11 Medical and Health Sciences, 17 Psychology and Cognitive Sciences, Oncology & Carcinogenesis
Abstract

OBJECTIVE:To examine prostate cancer (PCa) survivors' sexual help-seeking intentions, behaviours, and unmet needs. METHODS:In this prospective cohort study, men who underwent active, non-hormonal treatment completed baseline (N = 558) and 6-month follow-up (N = 387) questionnaires. Theory of planned behaviour (TPB) constructs (sexual help-seeking intention, perceived behavioural control (PBC), subjective norm, attitude), masculine values (e.g., sexual importance/priority, emotional self-reliance), sex life and functioning, sexual supportive care needs, distress (anxiety, depression), and sexual help-seeking behaviour were assessed. RESULTS:Most men (M age = 64.6 years; M years post-diagnosis = 4.0) received prostatectomy (93%), reported severe erectile dysfunction (52%), ≥ 1 unmet sexual care need (66%), and sought help from a doctor (baseline 52%, follow-up 42%). Sexual care needs were significantly associated with poorer erectile function, reduced satisfaction with sex-life, valuing sex as important/integral to identity (masculine values), and increased depression (p ≤ 0.001). Sexual help-seeking intentions were significantly associated with valuing sex as important/integral to identity, recent help-seeking, greater confidence/control, perceiving support from important others, and positive attitudes, for sexual help-seeking (p < 0.001). Significant predictors of sexual help-seeking (follow-up) were baseline intentions, recent help-seeking (p < 0.001), and increased anxiety (p < 0.05). CONCLUSIONS:Men's unmet sexual care needs, sexual help-seeking intentions, and behaviour appear driven by the importance/value attributed to sex, distress, positive feelings, support from others, and confidence for help-seeking. Psychosocial providers are well-placed to address men's concerns, yet few sought their assistance. Interventions to improve men's access to effective sexual care are needed, particularly focused on reframing masculine values about the importance of sex and leveraging TPB-based predictors of help-seeking.

Published
2020

27. 3rd IANA (International Academy on Nutrition and Aging) Meeting Nutrition, Exercise & Alzheimer and Clinical Trials on Sarcopenia August 1–2, 2008 Hyatt Regency Tamaya Resort 1300 Tuyuna Trail Santa Ana Pueblo, NM USA

Author

Andrieu, S., Barberger-Gateau, P., Raffaitin, C., Berr, C., Tzourio, C., Dartigues, J. -F., Gin, H., Fitten, L. J., Ortiz, F., Fairbanks, L., Bartzokis, G., Lu, P., Ringman, J., Heyn, P. C., Locher, J. L., Salvà, A., Andrieu, S., Fernández, E., Vellas, B., van de Rest, O., Geleijnse, J. M., Kok, F. J., van Staveren, W. A., Beekman, A. T. F., Hoefnagels, W. H. L., de Groot, C. P. G. M., Angevaren, M., Aufdemkampe, G., Verhaar, H. J. J., Aleman, A., Vannees, L., Arkin, S., Florez, H., Gerstein, H., Sheridan, P., Bosch, J., Goldberg, R., Kaspar, K. M., Drawert, S. M., Marcus, R. L., Kidde, J., Dibble, L., Addison, O., LaStayo, P. C., Scarmeas, N., Stern, Y., Schupf, N., Luchsinger, J. A., Sharkey, J. R., Laditka, J. N., Laditka, S. B., Liu, R., Hochhalter, A., Robare, J. F., Türner, N., Judge, M., Foster, T. C., Erdos, B., Cudykier, I., Scarpace, P. J., Weiss, L. A., Bergstrom, J., Kritz-Silverstein, D., Barrett-Connor, Elizabeth, Yurko-Mauro, K., Nelson, E., Quinn, J., Sattler, F. R., Castaneda-Sceppa, C., Binder, E. F., Schroeder, E. T., Wang, Y., Bhasin, S., Kawakubo, M., Stewart, Y., Hahn, C., Colletti, P., Roubenoff, R., Yarasheski, K. E., Azen, S. P., Aoki, Y., Yamamoto, T., Otuka, T., Blanc-Bisson, C., Bourdel-Marchasson, I., Bocock, M. A., Keller, H. H., Bowman, G., Baxter, J., Oken, B., Frei, B., Traber, M., Leonard, S., Kaye, J., Shannon, J., Quinn, J., Carlsson, M., Gustafson, Y., Eriksson, S., Littbrand, H., Håglin, L., Danthiir, V., Wilson, C., Nettelbeck, T., Burns, N., Wittert, G., Noakes, M., Clifton, P., DiMaria-Ghalili, R. A., Grieger, J. A., Nowson, C. A., Wattanapenpaiboon, N. T., Holstein, J., Robinson, C., Hartmann, C., Rueb, S., Heffel, L., Dintaman, S., Reynolds, J., Fleming, L., Crull, M., Goldey, J., Serper, L. L., Hubbard, R., Westengard, J., Horning, M., Ishige, Y., Aoki, Y., Keller, H. H., Keller, H. H., LaStayo, P. C., Marcus, R. L., Smith, S., Kidde, J., Dibble, L., Butler, C., Hill, M., LaStayo, P. C., Marcus, R. L., Dibble, L., Kidde, J., Peters, C., Meier, W., Laughlin, G. A., Kritz-Silverstein, D., von Muhlen, D., Barrett-Connor, E., Olariu, L., Petcu, M., Tulcan, C., Pup, M., Otilingam, P., Gate, M., Pasinetti, G. M., Ray, B., Chauhan, N. B., Bailey, J. A., Lahiri, D. K., Shatenstein, B., Kergoat, M. -J., Reid, I., Chicoine, M. -E., Vaz, L., Stewart, R., Sabbah, W., Tsakos, G., D’Aiuto, F., Watt, R. G., Sturman, M., Kelly, J., Fleischman, D., Leurgans, S., Bennett, D., Morris, M. C., Suominen, M. H., Muurinen, S., Soini, H., Pitkälä, K. H., Yamamoto, T., Fujinoki, C., and Aoki, Y.

Published
2008
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