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Your search keyword '"Wojciechowski, Elizabeth"' showing total 25 results
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25 results on '"Wojciechowski, Elizabeth"'

5. Personalised orthotic therapy using 3D printing in children with Charcot-Marie-Tooth disease

Author

Wojciechowski, Elizabeth

Subjects
3D gait analysis, AFO, CMT, ankle-foot-orthoses, additive manufacturing
Abstract

Children with Charcot-Marie-Tooth disease (CMT), are often prescribed custom-made ankle-foot orthoses (AFO) to manage walking difficulty. These externally worn assistive devices are usually handmade using a plaster cast of the patient's lower limb followed by thermoplastic vacuum forming. This traditional approach is labour-intensive and provides limited design options, resulting in AFOs which are cumbersome and associated with low acceptability, discomfort and suboptimal biomechanical function. The aim of this PhD Thesis was to develop, redesign and evaluate 3D printed AFOs compared to traditional handmade AFOs for children with CMT. A systematic literature review revealed that 3D printing AFOs has many potential benefits over traditional methods, including the development of novel designs that optimise stiffness and energy dissipation, improve gait, comfort and fit. The relationship between functional ability in 60 children with CMT and associated gait deviations using 3D gait analysis was assessed. The results showed that not all children with CMT have the typically described foot drop, push-off deficit and ‘steppage gait’ pattern. Instead, three distinct gait patterns exist at the ankle, indicating patient-specific orthotic design pathways. In 12 children with CMT, traditional handmade AFOs, replicated and iteratively redesigned 3D printed AFOs were compared to a shoe only condition using 3D gait analysis, in-shoe pedobarography and a patient satisfaction scale. Replicated 3D printed AFOs were comparable to traditional AFOs for all gait outcomes and patient satisfaction scores. Iteratively redesigned 3D printed AFOs reduced mass by, on average, 35% and improved ankle plantarflexion angle during the push-off phase of gait by up to 7°. The design, gait and acceptability of traditionally handmade AFOs can be replicated and redesigned with 3D printing in children with CMT.

Published
2020

14. Safety and efficacy of progressive resistance exercise for Charcot-Marie-Tooth disease in children: a randomised, double-blind, sham-controlled trial

Author

Burns, Joshua, primary, Sman, Amy D, additional, Cornett, Kayla M D, additional, Wojciechowski, Elizabeth, additional, Walker, Terri, additional, Menezes, Manoj P, additional, Mandarakas, Melissa R, additional, Rose, Kristy J, additional, Bray, Paula, additional, Sampaio, Hugo, additional, Farrar, Michelle, additional, Refshauge, Kathryn M, additional, Raymond, Jacqueline, additional, Burns, Joshua, additional, Baldwin, Jennifer, additional, McKay, Marnee J, additional, Mudge, Anita, additional, Purcell, Leanne, additional, Miller, Clare, additional, Gray, Kelly, additional, Harman, Meghan, additional, Gabrael, Natalie, additional, and Ouvrier, Robert A, additional

Published
2017
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19. Magnetic resonance imaging of the anterior compartment of the lower leg is a biomarker for weakness, disability, and impaired gait in childhood Charcot-Marie-Tooth disease.

Author

Cornett, Kayla M. D., Wojciechowski, Elizabeth, Sman, Amy D., Walker, Terri, Menezes, Manoj P., Bray, Paula, Halaki, Mark, Burns, Joshua, Sman, D., Mandarakas, Melissa R., Rose, Kristy J., Baldwin, Jennifer, McKay, Marnee J., Refshauge, Kathryn M., Raymond, Jacqueline, Sampaio, Hugo, Mudge, Anita, Purcell, Leanne, Miller, Clare, and Gray, Kelly

Subjects
*CHARCOT-Marie-Tooth disease, *COMPARATIVE studies, *GAIT disorders, *DIGITAL image processing, *LEG, *MAGNETIC resonance imaging, *RESEARCH methodology, *MEDICAL cooperation, *MUSCLE strength, *NEUROLOGICAL disorders, *PEOPLE with disabilities, *RESEARCH, *EVALUATION research, *SKELETAL muscle, *MUSCLE weakness, *DISEASE complications
Abstract

Introduction: Biomarkers of disease severity in Charcot-Marie-Tooth disease (CMT) are required to evaluate early responses to treatment. In this study we used magnetic resonance imaging (MRI) to evaluate the relationship between muscle volume and intramuscular fat accumulation with weakness, disability, and impaired gait in affected children and adolescents.Methods: Fifty-five participants underwent MRI of the anterior compartment of the lower leg. Muscle and fat volumes were calculated. Strength was measured using hand-held dynamometry, disability using the CMT Pediatric Scale, and 3-dimensional gait analysis using an 8-camera Vicon Nexus motion capture system.Results: Lower muscle volume was significantly associated with reduced dorsiflexion strength, increased disability, impaired gait profile score, and foot drop. Intramuscular fat accumulation was associated with reduced dorsiflexion strength and impaired gait profile score.Discussion: The MRI protocol described was feasible, reliable, and sensitive to the magnitude of weakness, disability, and walking difficulties in children with CMT. Muscle Nerve 59:213-217, 2019. [ABSTRACT FROM AUTHOR]

Published
2019
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20. A case review: designing a New Patient Education System

Author

Wojciechowski, Elizabeth and Cichowski, Kristine

Subjects
Patient education -- Usage, Disabled persons -- Educational aspects, Disabled persons -- Health aspects, Health
Abstract

Table of Contents Abstract Introduction Methodology Limitations Summary and Recommendations for Future Research References Abstract With shorter lengths of hospital stay, an increase in the number of persons with chronic [...]

Published
2007

22. Monitoring the resource requests of an innovative health resource center for patients and families with disabilities and professionals: the first six months

Author

Wojciechowski, Elizabeth A.

Subjects
Disabled persons -- Statistics, Disabled persons -- Care and treatment, Disability rights, Health
Abstract

Abstract Disability is a public health concern. An estimated 68 million Americans have activity limitations and an estimated 4.4 million (6.5%) of children under 18 years of age who are [...]

Published
2005

25. How does rectus femoris fibrosis affect gait?

Author

Balakrishnan S, Purcell LN, Mudge AJ, Wojciechowski EA, Burns J, and Axt MW

Subjects
Child, Preschool, Female, Fibrosis, Humans, Range of Motion, Articular, Gait physiology, Injections, Intramuscular adverse effects, Movement Disorders etiology, Muscular Diseases etiology, Quadriceps Muscle pathology
Abstract

We report on a female patient with stiff-knee gait resulting from rectus femoris fibrosis, following multiple injections into the quadriceps musculature. Treatment planning and outcome were aided by instrumented three-dimensional gait analysis. One year after surgery, improvements were found in walking speed, step length, anterior pelvic tilt, knee flexion in swing, and ankle dorsiflexion in swing. Instrumented three-dimensional gait analysis was a useful tool for characterizing gait impairments and detecting changes after surgical intervention. Intramuscular injections into the rectus femoris muscle should be avoided to prevent stiff-knee gait and associated disability.

Published
2014
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