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Your search keyword '"Won, Hojeong"' showing total 22 results
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22 results on '"Won, Hojeong"'

9. Specificity of clinical decision support tools for vedolizumab and ustekinumab in biologically naïve patients with Crohn's disease

Author

Kim, Ji Eun, Won, Hojeong, Kim, Young-Ho, Kim, Eun Ran, Hong, Sung Noh, and Chang, Dong Kyung

Subjects
Treatment Outcome, Crohn Disease, Gastroenterology, Humans, Ustekinumab, Antibodies, Monoclonal, Humanized, Decision Support Systems, Clinical
Abstract

Clinical decision support tools (CDST) were developed to predict drug response to various biological treatments for Crohn’s disease (CD). This study investigated whether CDSTs for vedolizumab (V-CDST) and ustekinumab (U-CDST) can be used as prognostic or drug-specific markers to predict response. A hypothetical scenario involving 872 patients with CD who were exposed to the first biological therapy at Samsung Medical Center between 1995 and 2020 is presented. V-CDST & U-CDST were calculated based on clinical and laboratory data immediately before the first biologic was initiated. The Cumulative Link Mixed Model (CLMM) test, weighted Kappa and plot, and Spearman’s correlation was used to determine the degree of agreement and difference between the two tools. 25% of all patients diagnosed with biologically naïve CD were categorized into different probability groups using V-CDST and U-CDST. The difference between the two tools was significantly based on a two-sample paired ordinal test with Cumulative Link Mixed Model (CLMM) (p-value < .001). Concordance between the two tools with a total of 654 subjects (75% of all patients) showed a similar probability (weighted Kappa: 0.47, 95% CI: 0.41–0.52). V-CDST and U-CDST are useful in selecting vedolizumab or ustekinumab in 25% of biologically naïve CD patients in our hypothetical scenario.

Published
2021

18. Comparison of clinical outcomes between passive scattering versus pencil-beam scanning proton beam therapy for hepatocellular carcinoma

Author

Yoo, Gyu Sang, primary, Yu, Jeong Il, additional, Cho, Sungkoo, additional, Jung, Sang Hoon, additional, Han, Youngyih, additional, Park, Seyjoon, additional, Oh, Yoonjin, additional, Lee, Boram, additional, Park, Hee Chul, additional, Lim, Do Hoon, additional, Choi, Moon Seok, additional, and Won, Hojeong, additional

Published
2020
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20. Specificity of clinical decision support tools for vedolizumab and ustekinumab in biologically naïve patients with Crohn's disease.

Author

Kim, Ji Eun, Won, Hojeong, Kim, Young-Ho, Kim, Eun Ran, Hong, Sung Noh, and Chang, Dong Kyung

Subjects
*CROHN'S disease, *VEDOLIZUMAB, *BIOTHERAPY
Abstract

Clinical decision support tools (CDST) were developed to predict drug response to various biological treatments for Crohn's disease (CD). This study investigated whether CDSTs for vedolizumab (V-CDST) and ustekinumab (U-CDST) can be used as prognostic or drug-specific markers to predict response. A hypothetical scenario involving 872 patients with CD who were exposed to the first biological therapy at Samsung Medical Center between 1995 and 2020 is presented. V-CDST & U-CDST were calculated based on clinical and laboratory data immediately before the first biologic was initiated. The Cumulative Link Mixed Model (CLMM) test, weighted Kappa and plot, and Spearman's correlation was used to determine the degree of agreement and difference between the two tools. 25% of all patients diagnosed with biologically naïve CD were categorized into different probability groups using V-CDST and U-CDST. The difference between the two tools was significantly based on a two-sample paired ordinal test with Cumulative Link Mixed Model (CLMM) (p-value <.001). Concordance between the two tools with a total of 654 subjects (75% of all patients) showed a similar probability (weighted Kappa: 0.47, 95% CI: 0.41–0.52). V-CDST and U-CDST are useful in selecting vedolizumab or ustekinumab in 25% of biologically naïve CD patients in our hypothetical scenario. [ABSTRACT FROM AUTHOR]

Published
2022
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21. Randomized Controlled Trial Evaluating Postoperative Oral Nutritional Supplementation after Major Gastrointestinal Surgery

Author

Lee, Hyuk-Joon, primary, Kong, Seong-Ho, additional, Park, Jun Seok, additional, Lee, In Kyu, additional, Ryu, Seung-Wan, additional, Park, Young-Kyu, additional, Yang, Han-Kwang, additional, Han, Sang-Uk, additional, Yoon, Ki-Young, additional, Jeong, Seung-Yong, additional, Jeong, Mi Ran, additional, Hwang, Dae Wook, additional, Suh, Yun-Suhk, additional, Yoon, Yoo-Seok, additional, Seo, Kyung Won, additional, Park, Ji Won, additional, Byun, Chul-Su, additional, Hur, Hoon, additional, Won, Hojeong, additional, and Choi, Yunhee, additional

Published
2017
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