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Your search keyword '"Wong, Liane"' showing total 13 results
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13 results on '"Wong, Liane"'

5. Surgical placement of customized abdominal vagus nerve stimulating and gastrointestinal serosal surface recording electrodes

Author

Horn, Charles C, Wong, Liane, Shepard, Brook S, Gourash, William F, McLaughlin, Bryan L, Fisher, Lee E, and Ahmed, Bestoun H

Subjects
AcademicSubjects/MED00910, Case Report, jscrep/0160
Abstract

Bioelectronic medical approaches to control vagus nerve-to-organ signaling have the potential to treat cardiac, respiratory, gastrointestinal (GI) and metabolic diseases, such as obesity. Unlike cervical vagus nerve stimulation (VNS), abdominal VNS could provide specific therapeutic control of the GI tract without off-target effects on thoracic organs; however, surgical approaches for abdominal VNS electrode placement are not well established. Moreover, optimal device configurations and additional placement of GI recording electrodes for closed-loop control are largely unknown. We designed VNS cuff and GI planar serosal electrodes and tested placement of these devices in laparoscopic surgery in two cadavers. We determined that electrode positioning on the ventral abdominal vagus nerve and gastric antrum was feasible but other sites, such as the duodenum and proximal stomach, were more difficult. The current investigation can guide potential placement and design of VNS cuff and GI electrodes for development of closed-loop GI therapeutic devices.

Published
2021

7. Selective stimulation of the ferret abdominal vagus nerve with multi-contact nerve cuff electrodes

Author

Shulgach, Jonathan A., primary, Beam, Dylan W., additional, Nanivadekar, Ameya C., additional, Miller, Derek M., additional, Fulton, Stephanie, additional, Sciullo, Michael, additional, Ogren, John, additional, Wong, Liane, additional, McLaughlin, Bryan, additional, Yates, Bill J., additional, Horn, Charles C., additional, and Fisher, Lee E., additional

Published
2021
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8. MP54-11 SPINAL CORD STIMULATION AND MICROSTIMULATION OF DORSAL ROOT GANGLION WITH PENETRATING MICROELECTRODE ARRAYS ENABLES SELECTIVE ACTIVATION OF MICTURITION AND CONTINENCE REFLEXES

Author

Gopinath*, Chaitanya, primary, Jantz, Maria K., additional, Kumar, Ritesh, additional, Nanivadekar, Ameya, additional, Bose, Rohit, additional, Ogren, John I., additional, Chitnis, Girish, additional, Wong, Liane, additional, McLaughlin, Bryan L., additional, Fisher, Lee E., additional, and Gaunt, Robert A., additional

Published
2020
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11. SPARC: Spinal cord epidural stimulation and microstimulation of dorsal root ganglion with penetrating microelectrode arrays enables selective activation of micturition and continence reflexes.

Author

Gopinath, Chaitanya, primary, Jantz, Maria K., additional, Kumar, Ritesh, additional, Nanivadekar, Ameya C., additional, Ogren, John I., additional, Chitnis, Girish, additional, Wong, Liane, additional, McLaughlin, Bryan L., additional, Fisher, Lee E., additional, and Gaunt, Robert A., additional

Published
2020
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