Search

SAN DIEGO -- CD19-directed chimeric antigen receptor (CAR) T-cell therapy, which has transformed the treatment landscape for B-cell malignancies, is now showing great promise in at least three distinct autoantibody-dependent [...]

The US Food and Drug Administration (FDA) has approved lifileucel (Amtagvi, Iovance Biotherapeutics) for the treatment of certain adults with unresectable or metastatic melanoma, marking the first approval of a [...]

The Food and Drug Administration has approved nivolumab (Opdivo) for the treatment of completely resected stage IIB/C melanoma for patients aged 12 years and older, expanding the melanoma indication for [...]

Cervical cancer incidence in the United States decreased by about 1% per year from 2001 to 2017, but at the same time there was an increase in the incidence of [...]

A novel DNA test system that assesses a person's genetic predisposition for certain cancers - the first of its kind granted marketing authorization by the Food and Drug Administration - [...]

This is the second of a two-part article on the role of racism and bias in the U.S. maternal mortality crisis and part of an ongoing Ob.Gyn. News feature series [...]

April 11-17 marked the third annual national Black Maternal Health Week, an event launched in 2017 by the Atlanta-based Black Mamas Matter Alliance (BMMA), in part to 'deepen the national [...]

THE FOOD AND DRUG Administration has approved retifanlimab-dlwr (Zynyz), an intravenous programmed death-1 (PD-1) inhibitor, for the treatment of adults with metastatic or recurrent locally advanced Merkel cell carcinoma (MCC), [...]

Nearly 700 women died from pregnancy-related complications in the United States in 2018, and almost a third of those deaths were associated with cardiovascular disease, according to the latest data [...]

This article is the first in a series on maternal mortality. 'You're in really bad shape, kid. I don't know if you're gonna live through the night. I'm going to [...]

Imagine a patient suffering with horrible psoriasis for decades having failed 'every available treatment.' Imagine him living all that time with 'flaking, cracking, painful, itchy skin,' only to develop cirrhosis [...]

Many patients with early breast cancer are being undertreated, concludes a novel study that examined the management of such patients across various geographical regions across the United States. A standard [...]

Signs of pancreatic cancer that were missed on earlier imaging scans represent a 'huge window of lost opportunity,' say United Kingdom researchers who report a novel analysis. The study set [...]

EXPERT ANALYSIS FROM ACOG 2019 NASHVILLE, TENN. -- Medical management of early pregnancy loss and abortion is best achieved with both mifepristone and misoprostol, according to Sarah W. Prager, MD. [...]

Clinicians should offer biennial mammography to screen for breast cancer in asymptomatic average-risk women aged 50-74 years and should abandon clinical breast examinations (CBE) for screening in such women of [...]

CHICAGO -- Recent randomized, placebo-controlled, phase 3 trials of tocilizumab, abatacept, and riociguat for the treatment of systemic sclerosis each failed to reach its primary endpoint of change from baseline [...]

FROM THE NEW ENGLAND JOURNAL OF MEDICINECervical cancer was more likely to recur and overall survival was lower among patients who underwent minimally invasive vs. open abdominal radical hysterectomy, based [...]

A SINGLE DOSE of human papillomavirus (HPV) vaccine was highly effective at preventing oncogenic infection, rivaling the protection offered by multidose regimens, according to results from the KEN SHE trial, [...]

THE FOOD AND DRUG ADMINISTRATION has issued a safety alert, warning of a rare but concerning potential risk of squamous cell carcinoma (SCC) and various lymphomas in the scar tissue [...]

A sedentary lifestyle has already been linked with an increased risk for breast cancer based on data from observational studies, but a new study with different methodology provides stronger evidence [...]

More than two dozen patient advocacy organizations have raised alarms about a recent court ruling that could threaten patient access to no-cost preventive screenings, including cancer screenings. In a statement, [...]

THE FOOD AND DRUG ADMINISTRATION has issued a safety alert, warning of a rare but concerning potential risk of squamous cell carcinoma (SCC) and various lymphomas in the scar tissue [...]

IMIQUIMOD CREAM is a safe, effective, firstline alternative to surgery for the treatment of vulvar high-grade squamous intraepithelial lesions (vHSILs), suggest the results from the first randomized trial to compare [...]

ORLANDO -- Improvements in cardiovascular and renal outcomes seen after nearly 10 years of improved glucose control among participants in the Veterans Affairs Diabetes Trial (VADT) who received intensive glucose-lowering [...]

REPORTING FROM APA 2018 NEW YORK -- The overrepresentation of people with serious mental illness (SMI) in the criminal justice system has led to creation of a resource from the [...]

FROM NATURE A large-scale meta-analysis has verified that the gut microbiome does influence patients's response to immune checkpoint inhibitor (ICI) therapy in advanced melanoma, but the relationship appears to be [...]

PERIODONTAL DISEASE (PD) may increase the risk of sporadic colorectal cancer (CRC), findings from the population-based case-control COLDENT study suggest. The rate of new CRC diagnoses among individuals in the [...]

THE FOOD AND DRUG Administration has approved pembrolizumab (Keytruda) for the adjuvant treatment of stage IIB and IIC melanoma after complete resection in adults and children over age 12 years. [...]

A SINGLE DOSE of human papillomavirus (HPV) vaccine was highly effective at preventing oncogenic infection, rivaling the protection offered by multidose regimens, according to results from the KEN SHE trial, [...]

The U.S. opioid crisis and ongoing epidemic of chronic pain are inextricably intertwined, and psychiatrists are increasingly being called upon to intervene. In a June 2016 blog post penned in [...]

For Luanne Freer, MD, an expert in high-altitude pulmonary edema (HAPE) and founder and director of Everest ER, a nonprofit seasonal clinic at the Mt. Everest base camp in Nepal [...]

AT AADE 14 ORLANDO -- Emotional distress associated with a diabetes diagnosis explains many patients' difficulties with self-management, based on results from the DAWN2 study presented at the annual meeting [...]

AT THE AMERICAN COLLEGE OF PSYCHIATRISTS MEETING SAN ANTONIO -- Treatment adherence is a problem for about half of all psychiatric patients, but certain high-yield techniques for enhancing adherence can [...]

Breast density in women aged 65 years and older may confer an increased risk of invasive breast cancer, much as it does in women aged 40-65 years, a large prospective [...]

Breast density in women aged 65 years and older may confer an increased risk of invasive breast cancer, much as it does in women aged 40-65 years, a large prospective [...]

The Food and Drug Administration has approved pembrolizumab (Keytruda) monotherapy for locally advanced cutaneous squamous cell carcinoma (cSCC) that can't be cured by surgery or radiation. The July 6 approval [...]

THE AMERICAN SOCIETY of Clinical Oncology now recommends offering 1 year of adjuvant olaparib therapy to patients with early-stage HER2-negative, BRCA-mutated breast cancer who have completed chemotherapy and local treatment. [...]

In 1966, Dr. Charles Hammond was wrapping up a 2-year stint at the National Institutes of Health where he served at the behest of the military draft board. He had [...]

Physicians appear to have much greater odds of substance abuse and dependence disorders related to alcohol, opiates, and sedatives than their nonphysician counterparts, some estimates showed. The good news is [...]

Physicians appear to have much greater odds of substance abuse and dependence disorders related to alcohol, opiates, and sedatives than their nonphysician counterparts, some estimates showed. The good news is [...]

Physicians appear to have much greater odds of substance abuse and dependence disorders related to alcohol, opiates, and sedatives than their non-physician counterparts, some estimates showed. The good news is [...]

FROM ANNALS OF INTERNAL MEDICINE Women aged 50-74 years should undergo biennial screening mammography, and the decision to screen before age 50 should be individualized, according to a final recommendation [...]

Little has changed over the years with respect to the proportion of unplanned pregnancies in the United States, but the emergence--and increasing acceptance--of safe and reliable long-acting reversible contraceptives, or [...]

FROM ANNALS OF INTERNAL MEDICINE The U.S. Preventive Services Task Force has recommended against routine medical advice that healthy postmenopausal women use of vitamin D and calcium supplementation. In explaining [...]

In the United States, breast cancer mortality rates dropped every year for women across all age groups between 1989 and 2010, but after that, the trend stalled for those younger [...]