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1. Efficacy and Safety of a Novel Low-Dose Triple Single-Pill Combination Compared With Placebo for Initial Treatment of Hypertension

Author

Rodgers, Anthony, Salam, Abdul, Schutte, Aletta E., Cushman, William C., de Silva, H. Asita, Di Tanna, Gian Luca, Grobbee, Diederick, Narkiewicz, Krzysztof, Ojji, Dike B., Poulter, Neil R., Schlaich, Markus P., Oparil, Suzanne, Spiering, Wilko, Williams, Bryan, Wright, Jackson T., Jr., Gutierez, Alexis, Sanni, Aliu, Lakshman, Poopalan, McMullen, Deirdre, Ranasinghe, Gotabhaya, Gianacas, Chris, Shanthakumar, Mathangi, Liu, Xiaoqiu, Wang, Nelson, and Whelton, Paul

Published
2024
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2. Efficacy and safety of a novel low-dose triple single-pill combination of telmisartan, amlodipine and indapamide, compared with dual combinations for treatment of hypertension: a randomised, double-blind, active-controlled, international clinical trial

Author

Rodgers, Anthony, Salam, Abdul, Schutte, Aletta E, Cushman, William C, de Silva, H Asita, Di Tanna, Gian Luca, Grobbee, Diederick E, Narkiewicz, Krzysztof, Ojji, Dike B, Poulter, Neil R, Schlaich, Markus P, Oparil, Suzanne, Spiering, Wilko, Williams, Bryan, Wright, Jackson T, Jr, Lakshman, P, Uluwattage, W, Hay, P, Pereira, T, Amarasena, N, Ranasinghe, G, Gianacas, Chris, Shanthakumar, Mathangi, Liu, Xiaoqiu, Wang, Nelson, Gnanenthiran, Sonali R, and Whelton, Paul K

Published
2024
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3. Inflammation and Apparent Treatment-Resistant Hypertension in Patients With Chronic Kidney Disease

Author

Chen, Jing, Bundy, Joshua D, Hamm, L Lee, Hsu, Chi-Yuan, Lash, James, Miller, Edgar R, Thomas, George, Cohen, Debbie L, Weir, Matthew R, Raj, Dominic S, Chen, Hsiang-Yu, Xie, Dawei, Rao, Panduranga, Wright, Jackson T, Rahman, Mahboob, and He, Jiang

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Cardiovascular, Clinical Research, Kidney Disease, Hypertension, Detection, screening and diagnosis, 4.1 Discovery and preclinical testing of markers and technologies, 2.1 Biological and endogenous factors, Aetiology, Inflammatory and immune system, Renal and urogenital, Good Health and Well Being, Adult, Aged, Antihypertensive Agents, Biomarkers, Blood Pressure, Comorbidity, Cross-Sectional Studies, Cytokines, Drug Resistance, Female, Glomerular Filtration Rate, Humans, Inflammation, Male, Middle Aged, Renal Insufficiency, Chronic, Risk Factors, United States, Young Adult, cardiovascular diseases, hypertension, inflammation, patients, renal insufficiency, chronic, renal insufficiency, chronic, Cardiorespiratory Medicine and Haematology, Public Health and Health Services, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Clinical sciences
Abstract

Apparent treatment-resistant hypertension (ATRH) is highly prevalent and associated with cardiovascular disease risk in patients with chronic kidney disease. We analyzed the association of inflammatory biomarkers with ATRH and its complications in patients with chronic kidney disease. ATRH was defined as blood pressure ≥140/90 mm Hg while taking ≥3 antihypertensive medications or blood pressure

Published
2019

4. A Synopsis of the Evidence for the Science and Clinical Management of Cardiovascular-Kidney-Metabolic (CKM) Syndrome: A Scientific Statement From the American Heart Association

Author

Ndumele, Chiadi E., Neeland, Ian J., Tuttle, Katherine R., Chow, Sheryl L., Mathew, Roy O., Khan, Sadiya S., Coresh, Josef, Baker-Smith, Carissa M., Carnethon, Mercedes R., Després, Jean-Pierre, Ho, Jennifer E., Joseph, Joshua J., Kernan, Walter N., Khera, Amit, Kosiborod, Mikhail N., Lekavich, Carolyn L., Lewis, Eldrin F., Lo, Kevin B., Ozkan, Bige, Palaniappan, Latha P., Patel, Sonali S., Pencina, Michael J., Powell-Wiley, Tiffany M., Sperling, Laurence S., Virani, Salim S., Wright, Jackson T., Rajgopal Singh, Radhika, Elkind, Mitchell S.V., and Rangaswami, Janani

Published
2023
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5. Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association

Author

Ndumele, Chiadi E., Rangaswami, Janani, Chow, Sheryl L., Neeland, Ian J., Tuttle, Katherine R., Khan, Sadiya S., Coresh, Josef, Mathew, Roy O., Baker-Smith, Carissa M., Carnethon, Mercedes R., Despres, Jean-Pierre, Ho, Jennifer E., Joseph, Joshua J., Kernan, Walter N., Khera, Amit, Kosiborod, Mikhail N., Lekavich, Carolyn L., Lewis, Eldrin F., Lo, Kevin B., Ozkan, Bige, Palaniappan, Latha P., Patel, Sonali S., Pencina, Michael J., Powell-Wiley, Tiffany M., Sperling, Laurence S., Virani, Salim S., Wright, Jackson T., Rajgopal Singh, Radhika, and Elkind, Mitchell S.V.

Published
2023
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8. Kidney Disease, Hypertension Treatment, and Cerebral Perfusion and Structure

Author

Whelton, Paul, Johnson, Karen C., Snyder, Joni, Bild, Diane, Bonds, Denise, Cook, Nakela, Cutler, Jeffrey, Fine, Lawrence, Kaufmann, Peter, Kimmel, Paul, Launer, Lenore, Moy, Claudia, Riley, William, Ryan, Laurie, Tolunay, Eser, Yang, Song, Reboussin, David, Williamson, Jeff, Ambrosius, Walter T., Applegate, William, Evans, Greg, Foy, Capri, Freedman, Barry I., Kitzman, Dalane, Lyles, Mary, Pajewski, Nick, Rapp, Steve, Rushing, Scott, Shah, Neel, Sink, Kaycee M., Vitolins, Mara, Wagenknecht, Lynne, Wilson, Valerie, Perdue, Letitia, Woolard, Nancy, Craven, Tim, Garcia, Katelyn, Gaussoin, Sarah, Lovato, Laura, Newman, Jill, Lovato, James, Lu, Lingyi, McLouth, Chris, Russell, Greg, Amoroso, Bobby, Davis, Patty, Griffin, Jason, Harris, Darrin, King, Mark, Lane, Kathy, Roberson, Wes, Steinberg, Debbie, Ashford, Donna, Babcock, Phyllis, Chamberlain, Dana, Christensen, Vickie, Cloud, Loretta, Collins, Christy, Cook, Delilah, Currie, Katherine, Felton, Debbie, Harpe, Stacy, Howard, Marjorie, Lewis, Michelle, Nance, Pamela, Puccinelli-Ortega, Nicole, Russell, Laurie, Walker, Jennifer, Craven, Brenda, Goode, Candace, Troxler, Margie, Davis, Janet, Hutchens, Sarah, Killeen, Anthony A., Lukkari, Anna M., Ringer, Robert, Dillard, Brandi, Archibeque, Norbert, Warren, Stuart, Sather, Mike, Pontzer, James, Taylor, Zach, Soliman, Elsayed Z., Zhang, Zhu-Ming, Li, Yabing, Campbell, Chuck, Hensley, Susan, Hu, Julie, Keasler, Lisa, Barr, Mary, Taylor, Tonya, Bryan, R. Nick, Davatzikos, Christos, Nasarallah, Ilya, Desiderio, Lisa, Elliott, Mark, Borthakur, Ari, Battapady, Harsha, Erus, Guray, Smith, Alex, Wang, Ze, Doshi, Jimit, Wright, Jackson T., Jr., Rahman, Mahboob, Lerner, Alan J., Still, Carolyn, Wiggers, Alan, Zamanian, Sara, Bee, Alberta, Dancie, Renee, Thomas, George, Schreiber, Martin, Jr., Navaneethan, Sankar Dass, Hickner, John, Lioudis, Michael, Lard, Michelle, Marczewski, Susan, Maraschky, Jennifer, Colman, Martha, Aaby, Andrea, Payne, Stacey, Ramos, Melanie, Horner, Carol, Drawz, Paul, Raghavendra, Pratibha P., Ober, Scott, Mourad, Ronda, Pallaki, Muralidhar, Russo, Peter, Raghavendra, Pratibha, Fantauzzo, Pual, Tucker, Lisa, Schwing, Bill, Sedor, John R., Horwitz, Edward J., Schellling, Jeffrey R., O’Toole, John F., Humbert, Lisa, Tutolo, Wendy, White, Suzanne, Gay, Alishea, Clark, Walter, Jr., Hughes, Robin, Dobre, Mirela, Still, Carolyn H., Williams, Monique, Bhatt, Udayan, Hebert, Lee, Agarwal, Anil, Murphy, Melissa Brown, Ford, Nicole, Stratton, Cynthia, Baxter, Jody, Lykins, Alicia A., McKinley Neal Leena Hirmath, Alison, Kwame, Osei, Soe, Kyaw, Miser, William F., Sagrilla, Colleen, Johnston, Jan, Anaya, Amber, Mintos, Ashley, Howell, Angel A., Rogers, Kelly, Taylor, Sara, Ebersbacher, Donald, Long, Lucy, Bednarchik, Beth, Schnall, Adrian, Smith, Jonathan, Peysha, Lori, Leach, Lisa, Tribout, Megan, Harwell, Carla, Ellington, Pinkie, Banerji, Mary Ann, Ghody, Pranav, Rambaud, Melissa Vahídeh, Townsend, Raymond, Cohen, Debbie, Huan, Yonghong, Duckworth, Mark, Ford, Virginia, Leshner, Juliet, Davison, Ann, Veen, Sarah Vander, Gadegbeku, Crystal A., Gillespie, Avi, Paranjape, Anuradha, Amoroso, Sandra, Pfeffer, Zoe, Quinn, Sally B., He, Jiang, Chen, Jing, Lustigova, Eva, Malone, Erin, Krousel-Wood, Marie, Deichmann, Richard, Ronney, Patricia, Muery, Susan, Trapani, Donnalee, Rocco, Michael, Goff, David, Rodriguez, Carlos, Coker, Laura, Hawfield, Amret, Yeboah, Joseph, Crago, Lenore, Summerson, John, Hege, Anita, Diamond, Matt, Mulloy, Laura, Hodges, Marcela, Collins, Michelle, Weathers, Charlene, Anderson, Heather, Stone, Emily, Walker, Walida, McWilliams, Andrew, Dulin, Michael, Kuhn, Lindsay, Standridge, Susan, Lowe, Lindsay, Everett, Kelly, Preston, Kelry, Norton, Susan, Gaines, Silena, Rizvi, Ali A., Sides, Andrew W., Herbert, Diamond, Hix, Matthew M., Whitmire, Melanie, Arnold, Brittany, Hutchinson, Philip, Espiritu, Joseph, Feinglos, Mark, Kovalik, Eugene, Gedon-Lipscomb, Georgianne, Evans, Kathryn, Thacker, Connie, Zimmer, Ronna, Furst, Mary, Mason, MaryAnn, Powell, James, Bolin, Paul, Zhang, Junhong, Pinion, Mary, Davis, Gail, Bryant, Winifred, Phelps, Presley, Garris-Sutton, Connie, Atkinson, Beatrice, Contreras, Gabriele, Suarez, Maritza, Schulman, Ivonne, Koggan, Don, Vassallo, Jackie, Peruyera, Gloria, Whittington, Sheri, Bethea, Cassandra, Gilliam, Laura, Pedley, Carolyn, Zurek, Geraldine, Baird, Miriam, Herring, Charles, Smoak, Mary Martha, Williams, Julie, Rogers, Samantha, Gordon, Lindsay, Kennedy, Erin, Belle, Beverly, McCorkle-Doomy, Jessica, Adams, Jonathan, Lopez, Ramon, Janavs, Juris, Rahbari-Oskoui, Frederic, Chapman, Arlene, Dollar, Allen, Williams, Olubunmi, Han, Yoosun, Haley, William, Fitzpatrick, Peter, Blackshear, Joseph, Shapiro, Brian, Harrell, Anna, Palaj, Arta, Henderson, Katelyn, Johnson, Ashley, Gonzalez, Heath, Robinson, Jermaine, Tamariz, Leonardo, Denizard, Jennifer, Barakat, Rody, Krishnamoorthy, Dhurga, Greenway, Frank, Monce, Ron, Church, Timothy, Hendrick, Chelsea, Yoches, Aimee, Sones, Leighanne, Baltazar, Markee, Pemu, Priscilla, Jones, Connie, Akpalu, Derrick, Cheung, Alfred K., Beddhu, Srinivasan, Chelune, Gordon, Childs, Jeffrey, Gren, Lisa, Randall, Anne, Dember, Laura, Soares, Denise, Yee, Jerry, Umanath, Kausik, Ogletree, Naima, Thaxton, Schawana, Campana, Karen, Sheldon, Dayna, MacArthur, Krista, Muhlestein, J. Brent, Allred, Nathan, Clements, Brian, Dhar, Ritesh, Meredith, Kent, Le, Viet, Miner, Edward, Orford, James, Riessen, Erik R., Ballantyne, Becca, Chisum, Ben, Johnson, Kevin, Peeler, Dixie, Chertow, Glenn, Tamura, Manju, Chang, Tara, Erickson, Kevin, Shen, Jenny, Stafford, Randall S., Zaharchuk, Gregory, Del Cid, Margareth, Dentinger, Michelle, Sabino, Jennifer, Sahay, Rukmani, Telminova, Ekaterina, Weiner, Daniel E., Sarnak, Mark, Chan, Lily, Civiletto, Amanda, Heath, Alyson, Kantor, Amy, Jain, Priyanka, Kirkpatrick, Bethany, Well, Andrew, Yuen, Barry, Chonchol, Michel, Farmer, Beverly, Farmer, Heather, Greenwald, Carol, Malaczewski, Mikaela, Lash, James, Porter, Anna, Ricardo, Ana, Rosman, Robert T., Cohan, Janet, Barrera, Nieves Lopez, Meslar, Daniel, Meslar, Patricia, Conroy, Margaret, Unruh, Mark, Hess, Rachel, Jhamb, Manisha, Thomas, Holly, Fazio, Pam, Klixbull, Elle, Komlos-Weimer, Melissa, Mandich, LeeAnne, Vita, Tina, Toto, Robert, Van Buren, Peter, Inrig, Julia, Cruz, Martha, Lightfoot, Tammy, Wang, Nancy, Webster, Lori, Raphael, Kalani, Stults, Barry, Zaman, Tahir, Simmons, Debra, Lavasani, Tooran, Filipowicz, Rebecca, Wei, Guo, Miller, Gracie Mary, Harerra, Jenice, Christensen, Jeff, Giri, Ajay, Chen, Xiaorui, Anderton, Natalie, Jensen, Arianna, Lewis, Julia, Burgner, Anna, Dwyer, Jamie P., Schulman, Gerald, Herrud, Terri, Leavell, Ewanda, McCray, Tiffany, McNeil-Simaan, Edwina, Poudel, Munmun, Reed, Malia, Sika, Mohammed, Woods, Delia, Zirkenbach, Janice L., Raj, Dominic S., Cohen, Scott, Patel, Samir, Velasquez, Manuel, Bastian, Roshni S., Wing, Maria, Roy-Chaudhury, Akshay, Depner, Thomas, Dalyrymple, Lorien, Kaysen, George, Anderson, Susan, Nord, John, Ix, Joachim H., Goldenstein, Leonard, Miracle, Cynthia M., Forbang, Nketi, Mircic, Maja, Thomas, Brenda, Tran, Tiffany, Rastogi, Anjay, Kim, Mihae, Rashid, Mohamad, Lizarraga, Bianca, Hocza, Amy, Sarmosyan, Kristine, Norris, Jason, Sharma, Tushar, Chioy, Amanda, Bernard, Eric, Cabrera, Eleanore, Lopez, Christina, Nunez, Susana, Riad, Joseph, Schweitzer, Suzanne, Sirop, Siran, Thomas, Sarah, Wada, Lauren, Kramer, Holly, Bansal, Vinod, Taylor, Corliss E., Segal, Mark S., Hall, Karen L., Kazory, Amir, Gilbert, Lesa, Owens, Linda, Poulton, Danielle, Whidden, Elaine, Wiggins, Jocelyn, Blaum, Caroline, Nyquist, Linda, Min, Lillian, Gure, Tanya, Lewis, Ruth, Mawby, Jennifer, Robinson, Eileen, Oparil, Suzanne, Lewis, Cora E., Bradley, Virginia, Calhoun, David, Glasser, Stephen, Jenkins, Kim, Ramsey, Tom, Qureshi, Nauman, Ferguson, Karen, Haider, Sumrah, James, Mandy, Jones, Christy, Renfroe, Kim, Seay, April, Weigart, Carrie, Thornley-Brown, Denyse, Rizik, Dana, Cotton, Bari, Fitz-Gerald, Meredith, Grimes, Tiffany, Johnson, Carolyn, Kennedy, Sara, Mason, Chanel, Rosato-Burson, Lesa, Willingham, Robin, Judd, Eric, Breaux-Shropshire, Tonya, Cook, Felice, Medina, Julia, Ghazi, Lama, Bhatt, Hemal, Lewis, James, Brantley, Roman, Brouilette, John, Glaze, Jeffrey, Hall, Stephanie, Hiott, Nancy, Tharpe, David, Boddy, Spencer, Mack, Catherine, Womack, Catherine, Asao, Keiko, Griffin, Beate, Hendrix, Carol, Johnson, Karen, Jones, Lisa, Towers, Chelsea, Punzi, Henry, Cassidy, Kathy, Schumacher, Kristin, Irizarry, Carmen, Colon, Ilma, Colon-Ortiz, Pedro, Colón-Hernández, Pedro J., Carrasquillo-Navarro, Orlando J., Carrasquillo, Merari, Vazquez, Nivea, Sosa-Padilla, Miguel, Cintron-Pinero, Alex, Ayala, Mayra, Pacheco, Olga, Rivera, Catalina, Sotomayor-Gonzalez, Irma, Claudio, Jamie, Lazaro, Jose, Arce, Migdalia, Heres, Lourdes, Perez, Alba, Tavarez-Valle, Jose, Arocho, Ferlinda, Torres, Mercedes, Vazquez, Melvaliz, Aurigemma, Gerard P., Takis-Smith, Rebecca, Andrieni, Julia, Bodkin, Noelle, Chaudhary, Kiran, Hu, Paula, Kostis, John, Cosgrove, Nora, Bankowski, Denise, Boleyn, Monica, Casazza, Laurie, Giresi, Victoria, Patel, Tosha, Squindo, Erin, Wu, Yan, Henson, Zeb, Wofford, Marion, Lowery, Jessica, Minor, Deborah, Harkins, Kimberley, Auchus, Alexander, Flessner, Michael, Adair, Cathy, Asher, Jordan, Loope, Debbie, Cobb, Rita, Venegas, Reiner, Bigger, Thomas, Bello, Natalie, Homma, Shunichi, Donovan, Daniel, Lopez-Jimenez, Carlos, Tirado, Amilcar, Getaneh, Asqual, Tang, Rocky, Durant, Sabrina, Maurer, Mathew, Teruya, Sergio, Helmke, Stephen, Alvarez, Julissa, Campbell, Ruth, Pisoni, Roberto, Sturdivant, Rachel, Brooks, Deborah, Counts, Caroline, Hunt, Vickie, Spillers, Lori, Brautigam, Donald, Kitchen, Timothy, Gorman, Timothy, Sayers, Jessica, Button, Sarah, Chiarot, June, Fischer, Rosemary, Lyon, Melissa, Resnick, Maria, Hodges, Nicole, Ferreira, Jennifer, Cushman, William, Wall, Barry, Nichols, Linda, Burns, Robert, Martindale-Adams, Jennifer, Berlowitz, Dan, Clark, Elizabeth, Walsh, Sandy, Geraci, Terry, Huff, Carol, Shaw, Linda, Servilla, Karen, Vigil, Darlene, Barrett, Terry, Sweeney, Mary Ellen, Johnson, Rebecca, McConnell, Susan, Salles, Khadijeh Shahid, Watson, Francoise, Schenk, Cheryl, Whittington, Laura, Maher, Maxine, Williams, Jonathan, Swartz, Stephen, Conlin, Paul, Alexis, George, Lamkin, Rebecca, Underwood, Patti, Gomes, Helen, Rosendorff, Clive, Atlas, Stephen, Khan, Saadat, Gonzalez, Waddy, Barcham, Samih, Kwon, Lawrence, Matar, Matar, Adhami, Anwar, Basile, Jan, John, Joseph, Ham, Deborah, Baig, Hadi, Saklayen, Mohammed, Yap, Jason, Neff, Helen, Miller, Carol, Zheng-Phelan, Ling, Gappy, Saib, Rau, Shiva, Raman, Arathi, Berchou, Vicki, Jones, Elizabeth, Olgren, Erin, Marbury, Cynthia, Yudd, Michael, Sastrasinh, Sithiporn, Michaud, Jennine, Fiore, Jessica, Kutza, Marianne, Shorr, Ronald, Mount, Rattana, Dunn, Helen, Stinson, Susan, Hunter, Jessica, Taylor, Addison, Bates, Jeffery, Anderson, Catherine, Kirchner, Kent, Stubbs, Jodi, Hinton, Ardell, Spencer, Anita, Sharma, Santosh, Wiegmann, Thomas, Mehta, Smita, Krause, Michelle, Dishongh, Kate, Childress, Richard, Gyamlani, Geeta, Niakan, Atossa, Thompson, Cathy, Moody, Janelle, Gresham, Carolyn, Whittle, Jeffrey, Barnas, Gary, Wolfgram, Dawn, Cortese, Heidi, Johnson, Jonette, Roumie, Christianne, Hung, Adriana, Wharton, Jennifer, Niesner, Kurt, Katz, Lois, Richardson, Elizabeth, Brock, George, Holland, Joanne, Dixon, Troy, Zias, Athena, Spiller, Christine, Baker, Penelope, Felicetta, James, Rehman, Shakaib, Bingham, Kelli, Watnick, Suzanne, Cohen, David, Weiss, Jessica, Johnston, Tera, Giddings, Stephen, Yamout, Hala, Klein, Andrew, Rowe, Caroline, Vargo, Kristin, Waidmann, Kristi, Papademetriou, Vasilios, Elkhoury, Jean Pierre, Gregory, Barbara, Amodeo, Susan, Bloom, Mary, Goldfarb-Waysman, Dalia, Treger, Richard, Kashefi, Mehran, Huang, Christina, Knibloe, Karen, Ishani, Areef, Slinin, Yelena, Olney, Christine, Rust, Jacqueline, Fanti, Paolo, Dyer, Christopher, Bansal, Shweta, Dunnam, Monica, Hu, Lih-Lan, Zarate-Abbott, Perla, Kurella Tamura, Manjula, Pajewski, Nicholas M., Zaharchuk, Greg, Rapp, Stephen R., Auchus, Alexander P., Haley, William E., Kendrick, Jessica, Roumie, Christianne L., Williamson, Jeff D., Detre, John A., Dolui, Sudipto, and Nasrallah, Ilya M.

Published
2022
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9. Association of Pulse Wave Velocity With Chronic Kidney Disease Progression and Mortality

Author

Townsend, Raymond R, Anderson, Amanda Hyre, Chirinos, Julio A, Feldman, Harold I, Grunwald, Juan E, Nessel, Lisa, Roy, Jason, Weir, Matthew R, Wright, Jackson T, Bansal, Nisha, Hsu, Chi-yuan, Appel, Lawrence J, Go, Alan S, He, Jiang, Kusek, John W, Lash, James P, Ojo, Akinlolu, and Rahman, Mahboob

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Kidney Disease, Aging, Clinical Research, Prevention, Detection, screening and diagnosis, 4.1 Discovery and preclinical testing of markers and technologies, Renal and urogenital, Good Health and Well Being, Adult, Aged, Blood Flow Velocity, Blood Pressure, Carotid Arteries, Cause of Death, Disease Progression, Female, Glomerular Filtration Rate, Humans, Hypertension, Male, Middle Aged, Pulse Wave Analysis, Renal Insufficiency, Chronic, Retrospective Studies, Survival Rate, United States, Young Adult, follow-up studies, humans, kidney failure, chronic, renal insufficiency, chronic, vascular stiffness, CRIC Study Investigators, Cardiorespiratory Medicine and Haematology, Public Health and Health Services, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Clinical sciences
Abstract

Patients with chronic kidney diseases (CKDs) are at risk for further loss of kidney function and death, which occur despite reasonable blood pressure treatment. To determine whether arterial stiffness influences CKD progression and death, independent of blood pressure, we conducted a prospective cohort study of CKD patients enrolled in the CRIC study (Chronic Renal Insufficiency Cohort). Using carotid-femoral pulse wave velocity (PWV), we examined the relationship between PWV and end-stage kidney disease (ESRD), ESRD or halving of estimated glomerular filtration rate, or death from any cause. The 2795 participants we enrolled had a mean age of 60 years, 56.4% were men, 47.3% had diabetes mellitus, and the average estimated glomerular filtration rate at entry was 44.4 mL/min per 1.73 m2 During follow-up, there were 504 ESRD events, 628 ESRD or halving of estimated glomerular filtration rate events, and 394 deaths. Patients with the highest tertile of PWV (>10.3 m/s) were at higher risk for ESRD (hazard ratio [95% confidence interval], 1.37 [1.05-1.80]), ESRD or 50% decline in estimated glomerular filtration rate (hazard ratio [95% confidence interval], 1.25 [0.98-1.58]), or death (hazard ratio [95% confidence interval], 1.72 [1.24-2.38]). PWV is a significant predictor of CKD progression and death in people with impaired kidney function. Incorporation of PWV measurements may help define better the risks for these important health outcomes in patients with CKDs. Interventions that reduce aortic stiffness deserve study in people with CKD.

Published
2018

11. Estimated GFR Variability and Risk of Cardiovascular Events and Mortality in SPRINT (Systolic Blood Pressure Intervention Trial)

Author

Malhotra, Rakesh, Katz, Ronit, Jotwani, Vasantha, Agarwal, Adhish, Cohen, Debbie L., Cushman, William C., Ishani, Areef, Killeen, Anthony A., Kitzman, Dalane W., Oparil, Suzanne, Papademetriou, Vasilios, Parikh, Chirag R., Raphael, Kalani L., Rocco, Michael V., Tamariz, Leonardo J., Whelton, Paul K., Wright, Jackson T., Jr., Shlipak, Michael G., and Ix, Joachim H.

Published
2021
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12. Racial/Ethnic Differences in Left Ventricular Structure and Function in Chronic Kidney Disease: The Chronic Renal Insufficiency Cohort.

Author

Ahmad, Faraz S, Cai, Xuan, Kunkel, Katherine, Ricardo, Ana C, Lash, James P, Raj, Dominic S, He, Jiang, Anderson, Amanda H, Budoff, Matthew J, Wright Nunes, Julie A, Roy, Jason, Wright, Jackson T, Go, Alan S, St John Sutton, Martin G, Kusek, John W, Isakova, Tamara, Wolf, Myles, and Keane, Martin G

Subjects
Hypertension, Prevention, Clinical Research, Cardiovascular, Kidney Disease, Renal and urogenital, Good Health and Well Being, Adult, Aged, Blacks, Blood Pressure, Cohort Studies, Cross-Sectional Studies, Electrocardiography, Ethnicity, Female, Heart Ventricles, Humans, Hypertrophy, Left Ventricular, Male, Middle Aged, Prevalence, Renal Insufficiency, Chronic, Socioeconomic Factors, Ventricular Dysfunction, Left, Ventricular Remodeling, Whites, Young Adult, blood pressure, echocardiography, hypertension, left ventricular hypertrophy, race and ethnicity, remodeling, renal insufficiency, CRIC Study Investigators, White People, Black People, Clinical Sciences, Cardiovascular System & Hematology
Abstract

BackgroundChronic kidney disease (CKD) is associated with increased risk of cardiovascular disease (CVD) and it is especially common among Blacks. Left ventricular hypertrophy (LVH) is an important subclinical marker of CVD, but there are limited data on racial variation in left ventricular structure and function among persons with CKD.MethodsIn a cross-sectional analysis of the Chronic Renal Insufficiency Cohort Study, we compared the prevalence of different types of left ventricular remodeling (concentric hypertrophy, eccentric hypertrophy, and concentric remodeling) by race/ethnicity. We used multinomial logistic regression to test whether race/ethnicity associated with different types of left ventricular remodeling independently of potential confounding factors.ResultsWe identified 1,164 non-Hispanic Black and 1,155 non-Hispanic White participants who completed Year 1 visits with echocardiograms that had sufficient data to categorize left ventricular geometry type. Compared to non-Hispanic Whites, non-Hispanic Blacks had higher mean left ventricular mass index (54.7 ± 14.6 vs. 47.4 ± 12.2 g/m2.7; P < 0.0001) and prevalence of concentric LVH (45.8% vs. 24.9%). In addition to higher systolic blood pressure and treatment with >3 antihypertensive medications, Black race/ethnicity was independently associated with higher odds of concentric LVH compared to White race/ethnicity (odds ratio: 2.73; 95% confidence interval: 2.02, 3.69).ConclusionIn a large, diverse cohort with CKD, we found significant differences in left ventricular mass and hypertrophic morphology between non-Hispanic Blacks and Whites. Future studies will evaluate whether higher prevalence of LVH contribute to racial/ethnic disparities in cardiovascular outcomes among CKD patients.

Published
2017

13. Coronary Artery Calcification and Risk of Cardiovascular Disease and Death Among Patients With Chronic Kidney Disease

Author

Chen, Jing, Budoff, Matthew J, Reilly, Muredach P, Yang, Wei, Rosas, Sylvia E, Rahman, Mahboob, Zhang, Xiaoming, Roy, Jason A, Lustigova, Eva, Nessel, Lisa, Ford, Virginia, Raj, Dominic, Porter, Anna C, Soliman, Elsayed Z, Wright, Jackson T, Wolf, Myles, and He, Jiang

Subjects
Heart Disease, Clinical Research, Heart Disease - Coronary Heart Disease, Prevention, Kidney Disease, Aging, Cardiovascular, Atherosclerosis, Renal and urogenital, Good Health and Well Being, Adult, Aged, Cardiovascular Diseases, Cause of Death, Cohort Studies, Comorbidity, Coronary Artery Disease, Female, Heart Failure, Humans, Incidence, Male, Middle Aged, Mortality, Myocardial Infarction, Proportional Hazards Models, Prospective Studies, Renal Insufficiency, Chronic, Risk Assessment, Risk Factors, Tomography, X-Ray Computed, Vascular Calcification, Young Adult, CRIC Investigators
Abstract

ImportanceCoronary artery calcification (CAC) is highly prevalent in dialysis-naive patients with chronic kidney disease (CKD). However, there are sparse data on the association of CAC with subsequent risk of cardiovascular disease and all-cause mortality in this population.ObjectiveTo study the prospective association of CAC with risk of cardiovascular disease and all-cause mortality among dialysis-naive patients with CKD.Design, setting, and participantsThe prospective Chronic Renal Insufficiency Cohort study recruited adults with an estimated glomerular filtration rate of 20 to 70 mL/min/1.73 m2 from 7 clinical centers in the United States. There were 1541 participants without cardiovascular disease at baseline who had CAC scores.ExposuresCoronary artery calcification was assessed using electron-beam or multidetector computed tomography.Main outcomes and measuresIncidence of cardiovascular disease (including myocardial infarction, heart failure, and stroke) and all-cause mortality were reported every 6 months and confirmed by medical record adjudication.ResultsDuring an average follow-up of 5.9 years in 1541 participants aged 21 to 74 years, there were 188 cardiovascular disease events (60 cases of myocardial infarction, 120 heart failures, and 27 strokes; patients may have had >1 event) and 137 all-cause deaths. In Cox proportional hazards models adjusted for age, sex, race, clinical site, education level, physical activity, total cholesterol level, high-density lipoprotein cholesterol level, systolic blood pressure, use of antihypertensive treatment, current cigarette smoking, diabetes status, body mass index, C-reactive protein level, hemoglobin A1c level, phosphorus level, troponin T level, log N-terminal pro-B-type natriuretic peptide level, fibroblast growth factor 23 level, estimated glomerular filtration rate, and proteinuria, the hazard ratios associated with per 1 SD log of CAC were 1.40 (95% CI, 1.16-1.69; P

Published
2017

14. Effects of intensive versus standard blood pressure control on domain-specific cognitive function: a substudy of the SPRINT randomised controlled trial

Author

Rapp, Stephen R, Pajewski, Nicholas M, Auchus, Alexander P, Chelune, Gordon, Cheung, Alfred K, Cleveland, Maryjo L, Coker, Laura H, Crowe, Michael G, Cushman, William C, Cutler, Jeffery A, Davatzikos, Christos, Desiderio, Lisa, Doshi, Jimit, Erus, Guray, Fine, Lawrence J, Gaussoin, Sarah A, Harris, Darrin, Johnson, Karen C, Kimmel, Paul L, Tamura, Manjula K, Launer, Lenore J, Lerner, Alan J, Lewis, Cora E, Martindale-Adams, Jennifer, Moy, Claudia S, Nichols, Linda O, Oparil, Suzanne, Ogrocki, Paula K, Rahman, Mahboob, Nasrallah, Ilya M, Reboussin, David M, Rocco, Michael V, Sachs, Bonnie C, Sink, Kaycee M, Still, Carolyn H, Supiano, Mark A, Snyder, Joni K, Wadley, Virginia G, Walker, Jennifer, Weiner, Daniel E, Whelton, Paul K, Wilson, Valerie M, Woolard, Nancy, Wright, Jackson T, Jr., Wright, Clinton B, Williamson, Jeff D, Bryan, R Nick, Wilson, Valarie M, Whittle, Jeff C, Beddhu, Srinivasan, Berlowitz, Dan R, Bress, Adam P, Krousel-Wood, Marie, Miller, Eliza C, Rifkin, Dena E, Tamariz, Leonardo, Wolfgram, Dawn F, Yang, Mia, and Bryan, Robert Nick

Published
2020
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16. Ankle Brachial Index and Subsequent Cardiovascular Disease Risk in Patients With Chronic Kidney Disease

Author

Chen, Jing, Mohler, Emile R, Garimella, Pranav S, Hamm, L Lee, Xie, Dawei, Kimmel, Stephen, Townsend, Raymond R, Budoff, Matthew, Pan, Qiang, Nessel, Lisa, Steigerwalt, Susan, Wright, Jackson T, He, Jiang, Appel, Lawrence J, Feldman, Harold I, Go, Alan S, Kusek, John W, Lash, James P, Ojo, Akinlolu, and Rahman, Mahboob

Subjects
Cardiovascular, Heart Disease, Clinical Research, Kidney Disease, Detection, screening and diagnosis, 4.1 Discovery and preclinical testing of markers and technologies, Renal and urogenital, Good Health and Well Being, Adult, Aged, Ankle Brachial Index, Blood Pressure, Cardiovascular Diseases, Female, Glomerular Filtration Rate, Heart Failure, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Myocardial Infarction, Peripheral Arterial Disease, Prospective Studies, Renal Insufficiency, Chronic, Risk Factors, Young Adult, ankle brachial index, cardiovascular disease, chronic kidney disease, heart failure, mortality, myocardial infarction, peripheral arterial disease, CRIC Investigators, Cardiorespiratory Medicine and Haematology
Abstract

The clinical implications of ankle-brachial index (ABI) cutpoints are not well defined in patients with chronic kidney disease (CKD) despite increased prevalence of high ABI attributed to arterial stiffness. We examined the relationship of ABI with cardiovascular disease (CVD) and all-cause mortality among CKD patients. Three thousand six hundred twenty-seven participants without clinical peripheral artery disease (PAD) at baseline from the Chronic Renal Insufficiency Cohort Study were included. ABI was obtained per standard protocol and CVD events were confirmed by medical record adjudication. A U-shaped association of ABI with PAD, myocardial infarction (MI), composite CVD, and all-cause mortality was observed. Individuals with an ABI between 1.0 and

Published
2016

17. Rationale for a New Low-Dose Triple Single Pill Combination for the Treatment of Hypertension

Author

Global Health, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, MS Interne Geneeskunde, Rodgers, Anthony, Salam, Abdul, Cushman, William, de Silva, Asita, Di Tanna, Gian Luca, Gnanenthiran, Sonali R., Grobbee, Diederick, Narkiewicz, Krzysztof, Ojji, Dike, Oparil, Suzanne, Poulter, Neil, Schlaich, Markus P., Schutte, Aletta E., Spiering, Wilko, Williams, Bryan, Wright, Jackson T., Whelton, Paul, Global Health, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, MS Interne Geneeskunde, Rodgers, Anthony, Salam, Abdul, Cushman, William, de Silva, Asita, Di Tanna, Gian Luca, Gnanenthiran, Sonali R., Grobbee, Diederick, Narkiewicz, Krzysztof, Ojji, Dike, Oparil, Suzanne, Poulter, Neil, Schlaich, Markus P., Schutte, Aletta E., Spiering, Wilko, Williams, Bryan, Wright, Jackson T., and Whelton, Paul

Published
2024

18. Chronic kidney disease, atherosclerotic plaque characteristics on carotid magnetic resonance imaging, and cardiovascular outcomes

Author

Beddhu, Srinivasan, Boucher, Robert E., Sun, Jie, Balu, Niranjan, Chonchol, Michel, Navaneethan, Sankar, Chertow, Glenn M., Townsend, Raymond, Haley, William, Cheung, Alfred K., Conroy, Molly B., Raj, Dominic S., Xu, Dongxiang, George, Thomas, Yunis, Reem, Wei, Guo, Canton, Gador, Bates, Jeffrey, Chen, Jing, Papademetriou, Vasilios, Punzi, Henry, Wiggers, Alan, Wright, Jackson T., Greene, Tom, and Yuan, Chun

Published
2021
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19. General Principles, Etiologies, Evaluation, and Management in Older Adults

Author

Egan, Brent M., Rich, Michael W., Sutherland, Susan E., Wright, Jackson T., and Kjeldsen, Sverre E.

Abstract

Hypertension impacts most older adults as one of many multiple chronic conditions. A thorough evaluation is required to assess overall health, cardiovascular status, and comorbid conditions that impact treatment targets. In the absence of severe frailty or dementia, intensive treatment prevents more cardiovascular events than standard treatment and may slow cognitive decline. “Start low and go slow” is not the best strategy for many older adults as fewer cardiovascular events occur when hypertension is controlled within the first 3 to 6 months of treatment.

Published
2024
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20. Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial

Author

Langefeld, Carl D, Divers, Jasmin, Pajewski, Nicholas M, Hawfield, Amret T, Reboussin, David M, Bild, Diane E, Kaysen, George A, Kimmel, Paul L, Raj, Dominic S, Ricardo, Ana C, Wright, Jackson T, Sedor, John R, Rocco, Michael V, Freedman, Barry I, and Trial, on behalf of the Systolic Blood Pressure Intervention

Subjects
Hypertension, Cardiovascular, Kidney Disease, Clinical Trials and Supportive Activities, Atherosclerosis, Heart Disease, Prevention, Clinical Research, Renal and urogenital, Good Health and Well Being, African Americans, Apolipoprotein L1, Apolipoproteins, Cardiovascular Diseases, Female, Genetic Variation, Humans, Lipoproteins, HDL, Male, Middle Aged, Renal Insufficiency, Chronic, Systolic Blood Pressure Intervention Trial, Black or African American, Clinical Sciences, Urology & Nephrology
Abstract

Apolipoprotein L1 gene (APOL1) G1 and G2 coding variants are strongly associated with chronic kidney disease (CKD) in African Americans (AAs). Here APOL1 association was tested with baseline estimated glomerular filtration rate (eGFR), urine albumin:creatinine ratio (UACR), and prevalent cardiovascular disease (CVD) in 2571 AAs from the Systolic Blood Pressure Intervention Trial (SPRINT), a trial assessing effects of systolic blood pressure reduction on renal and CVD outcomes. Logistic regression models that adjusted for potentially important confounders tested for association between APOL1 risk variants and baseline clinical CVD (myocardial infarction, coronary, or carotid artery revascularization) and CKD (eGFR under 60 ml/min per 1.73 m(2) and/or UACR over 30 mg/g). AA SPRINT participants were 45.3% female with a mean (median) age of 64.3 (63) years, mean arterial pressure 100.7 (100) mm Hg, eGFR 76.3 (77.1) ml/min per 1.73 m(2), and UACR 49.9 (9.2) mg/g, and 8.2% had clinical CVD. APOL1 (recessive inheritance) was positively associated with CKD (odds ratio 1.37, 95% confidence interval 1.08-1.73) and log UACR estimated slope (β) 0.33) and negatively associated with eGFR (β -3.58), all significant. APOL1 risk variants were not significantly associated with prevalent CVD (1.02, 0.82-1.27). Thus, SPRINT data show that APOL1 risk variants are associated with mild CKD but not with prevalent CVD in AAs with a UACR under 1000 mg/g.

Published
2015

22. Rationale for a New Low-Dose Triple Single Pill Combination for the Treatment of Hypertension

Author

Rodgers, Anthony, primary, Salam, Abdul, additional, Cushman, William, additional, de Silva, Asita, additional, Di Tanna, Gian Luca, additional, Gnanenthiran, Sonali R., additional, Grobbee, Diederick, additional, Narkiewicz, Krzysztof, additional, Ojji, Dike, additional, Oparil, Suzanne, additional, Poulter, Neil, additional, Schlaich, Markus P., additional, Schutte, Aletta E., additional, Spiering, Wilko, additional, Williams, Bryan, additional, Wright, Jackson T., additional, and Whelton, Paul, additional

Published
2024
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25. APOL1 Risk Variants, Race, and Progression of Chronic Kidney Disease

Author

Parsa, Afshin, Kao, WH Linda, Xie, Dawei, Astor, Brad C, Li, Man, Hsu, Chi-yuan, Feldman, Harold I, Parekh, Rulan S, Kusek, John W, Greene, Tom H, Fink, Jeffrey C, Anderson, Amanda H, Choi, Michael J, Wright, Jackson T, Lash, James P, Freedman, Barry I, Ojo, Akinlolu, Winkler, Cheryl A, Raj, Dominic S, Kopp, Jeffrey B, He, Jiang, Jensvold, Nancy G, Tao, Kaixiang, Lipkowitz, Michael S, and Appel, Lawrence J

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Kidney Disease, Clinical Research, Minority Health, Health Disparities, Renal and urogenital, Metabolic and endocrine, Good Health and Well Being, Adult, Black or African American, Aged, Apolipoprotein L1, Apolipoproteins, Creatinine, Diabetes Complications, Disease Progression, Female, Genetic Predisposition to Disease, Glomerular Filtration Rate, Humans, Hypertension, Kidney Failure, Chronic, Lipoproteins, HDL, Male, Middle Aged, Multivariate Analysis, Polymorphism, Single Nucleotide, Proteinuria, Renal Insufficiency, Chronic, White People, AASK Study Investigators, CRIC Study Investigators, Medical and Health Sciences, General & Internal Medicine, Biomedical and clinical sciences, Health sciences
Abstract

BackgroundAmong patients in the United States with chronic kidney disease, black patients are at increased risk for end-stage renal disease, as compared with white patients.MethodsIn two studies, we examined the effects of variants in the gene encoding apolipoprotein L1 (APOL1) on the progression of chronic kidney disease. In the African American Study of Kidney Disease and Hypertension (AASK), we evaluated 693 black patients with chronic kidney disease attributed to hypertension. In the Chronic Renal Insufficiency Cohort (CRIC) study, we evaluated 2955 white patients and black patients with chronic kidney disease (46% of whom had diabetes) according to whether they had 2 copies of high-risk APOL1 variants (APOL1 high-risk group) or 0 or 1 copy (APOL1 low-risk group). In the AASK study, the primary outcome was a composite of end-stage renal disease or a doubling of the serum creatinine level. In the CRIC study, the primary outcomes were the slope in the estimated glomerular filtration rate (eGFR) and the composite of end-stage renal disease or a reduction of 50% in the eGFR from baseline.ResultsIn the AASK study, the primary outcome occurred in 58.1% of the patients in the APOL1 high-risk group and in 36.6% of those in the APOL1 low-risk group (hazard ratio in the high-risk group, 1.88; P

Published
2013

26. Orthostatic Hypotension, Hypertension Treatment, and Cardiovascular Disease

Author

Juraschek, Stephen P., primary, Hu, Jiun-Ruey, additional, Cluett, Jennifer L., additional, Ishak, Anthony M., additional, Mita, Carol, additional, Lipsitz, Lewis A., additional, Appel, Lawrence J., additional, Beckett, Nigel S., additional, Coleman, Ruth L., additional, Cushman, William C., additional, Davis, Barry R., additional, Grandits, Greg, additional, Holman, Rury R., additional, Miller, Edgar R., additional, Peters, Ruth, additional, Staessen, Jan A., additional, Taylor, Addison A., additional, Thijs, Lutgarde, additional, Wright, Jackson T., additional, and Mukamal, Kenneth J., additional

Published
2023
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27. Abstract 112: Effects Of Intensive Blood Pressure Treatment On Orthostatic Hypertension: An Individual-level Meta-analysis

Author

Juraschek, Stephen P, primary, Hu, Jiun-Ruey, additional, Cluett, Jennifer, additional, Mita, Carol, additional, Lipsitz, Lewis, additional, Appel, Lawrence J, additional, Beckett, Nigel, additional, Davis, Barry R, additional, Holman, Rury, additional, Miller, Edgar R, additional, Mukamal, Ken J, additional, Peters, Ruth, additional, Staessen, Jan A, additional, Taylor, Addison A, additional, Wright, Jackson T, additional, and Cushman, William C, additional

Published
2023
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29. Orthostatic Hypotension, Cardiovascular Outcomes, and Adverse Events: Results From SPRINT

Author

Juraschek, Stephen P., Taylor, Addison A., Wright, Jackson T., Jr, Evans, Gregory W, Miller, Edgar R., III, Plante, Timothy B., Cushman, William C., Gure, Tanya R., Haley, William E., Moinuddin, Imran, Nord, John, Oparil, Suzanne, Pedley, Carolyn, Roumie, Christianne L., Whittle, Jeff, Wiggers, Alan, Finucane, Ciarán, Anne Kenny, Rose, Appel, Lawrence J., and Townsend, Raymond R.

Published
2020
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33. Race/Ethnicity and Cardiovascular Outcomes in Adults With CKD: Findings From the CRIC (Chronic Renal Insufficiency Cohort) and Hispanic CRIC Studies

Author

Appel, Lawrence J., Feldman, Harold I., Go, Alan S., He, Jiang, Kusek, John W., Lash, James P., Ojo, Akinlolu, Rahman, Mahboob, Townsend, Raymond R., Ricardo, Ana C., Roy, Jason, Deo, Rajat, Fischer, Michael, Flack, John, Keane, Martin, Lora, Claudia, Steigerwalt, Susan, Tao, Kaixiang, Wolf, Myles, and Wright, Jackson T., Jr.

Published
2016
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34. APOL1 renal-risk variants associate with reduced cerebral white matter lesion volume and increased gray matter volume

Author

Freedman, Barry I., Gadegbeku, Crystal A., Bryan, R. Nick, Palmer, Nicholette D., Hicks, Pamela J., Ma, Lijun, Rocco, Michael V., Smith, S. Carrie, Xu, Jianzhao, Whitlow, Christopher T., Wagner, Benjamin C., Langefeld, Carl D., Hawfield, Amret T., Bates, Jeffrey T., Lerner, Alan J., Raj, Dominic S., Sadaghiani, Mohammad S., Toto, Robert D., Wright, Jackson T., Jr., Bowden, Donald W., Williamson, Jeff D., Sink, Kaycee M., Maldjian, Joseph A., Pajewski, Nicholas M., and Divers, Jasmin

Published
2016
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43. Effects of Intensive BP Control in CKD

Author

Cheung, Alfred K., Rahman, Mahboob, Reboussin, David M., Craven, Timothy E., Greene, Tom, Kimmel, Paul L., Cushman, William C., Hawfield, Amret T., Johnson, Karen C., Lewis, Cora E., Oparil, Suzanne, Rocco, Michael V., Sink, Kaycee M., Whelton, Paul K., Wright, Jackson T., Jr., Basile, Jan, Beddhu, Srinivasan, Bhatt, Udayan, Chang, Tara I., Chertow, Glenn M., Chonchol, Michel, Freedman, Barry I., Haley, William, Ix, Joachim H., Katz, Lois A., Killeen, Anthony A., Papademetriou, Vasilios, Ricardo, Ana C., Servilla, Karen, Wall, Barry, Wolfgram, Dawn, Yee, Jerry, Cheung, Alfred K., Rahman, Mahboob, Reboussin, David M., Craven, Timothy E., Greene, Tom, Kimmel, Paul L., Cushman, William C., Hawfield, Amret T., Johnson, Karen C., Lewis, Cora E., Oparil, Suzanne, Rocco, Michael V., Sink, Kaycee M., Whelton, Paul K., Wright, Jackson T., Jr., Basile, Jan, Beddhu, Srinivasan, Bhatt, Udayan, Chang, Tara I., Chertow, Glenn M., Chonchol, Michel, Freedman, Barry I., Haley, William, Ix, Joachim H., Katz, Lois A., Killeen, Anthony A., Papademetriou, Vasilios, Ricardo, Ana C., Servilla, Karen, Wall, Barry, Wolfgram, Dawn, and Yee, Jerry

Published
2017
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44. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Author

Whelton, Paul K., Carey, Robert M., Aronow, Wilbert S., Casey, Donald E., Jr, Collins, Karen J., Dennison Himmelfarb, Cheryl, DePalma, Sondra M., Gidding, Samuel, Jamerson, Kenneth A., Jones, Daniel W., MacLaughlin, Eric J., Muntner, Paul, Ovbiagele, Bruce, Smith, Sidney C., Jr, Spencer, Crystal C., Stafford, Randall S., Taler, Sandra J., Thomas, Randal J., Williams, Kim A., Sr, Williamson, Jeff D., and Wright, Jackson T., Jr

Published
2018
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45. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Author

Whelton, Paul K., Carey, Robert M., Aronow, Wilbert S., Casey, Donald E., Jr, Collins, Karen J., Dennison Himmelfarb, Cheryl, DePalma, Sondra M., Gidding, Samuel, Jamerson, Kenneth A., Jones, Daniel W., MacLaughlin, Eric J., Muntner, Paul, Ovbiagele, Bruce, Smith, Sidney C., Jr, Spencer, Crystal C., Stafford, Randall S., Taler, Sandra J., Thomas, Randal J., Williams, Kim A., Sr, Williamson, Jeff D., and Wright, Jackson T., Jr

Published
2018
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49. Longer-Term All-Cause and Cardiovascular Mortality With Intensive Blood Pressure Control

Author

Jaeger, Byron C., primary, Bress, Adam P., additional, Bundy, Joshua D., additional, Cheung, Alfred K., additional, Cushman, William C., additional, Drawz, Paul E., additional, Johnson, Karen C., additional, Lewis, Cora E., additional, Oparil, Suzanne, additional, Rocco, Michael V., additional, Rapp, Stephen R., additional, Supiano, Mark A., additional, Whelton, Paul K., additional, Williamson, Jeff D., additional, Wright, Jackson T., additional, Reboussin, David M., additional, and Pajewski, Nicholas M., additional

Published
2022
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