261 results on '"Wu, Chengyong"'
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2. Target proteins-regulated DNA nanomachine-electroactive substance complexes enable separation-free electrochemical detection of clinical exosome
3. Discovery of novel thiophene[3,2-d]pyrimidine-based tubulin inhibitors with enhanced antitumor efficacy for combined use with anti-pd-l1 immunotherapy in melanoma
4. Discovery and mechanistic insights into thieno[3,2-d]pyrimidine and heterocyclic fused pyrimidines inhibitors targeting tubulin for cancer therapy
5. Development and therapeutic implications of small molecular inhibitors that target calcium-related channels in tumor treatment
6. Smartphone and handheld fluorometer enable rapid point of care testing of Escherichia coli in urinary tract infections via specific proteolytic cleavage and cascade amplifications
7. Biomolecules-mediated electrochemical signals of Cu2+: Y-DNA nanomachines enable homogeneous rapid one-step assay of lung cancer circulating tumor cells
8. Current advances and development strategies of targeting son of sevenless 1 (SOS1) in drug discovery
9. Amphiphilic small molecule antimicrobials: From cationic antimicrobial peptides (CAMPs) to mechanism-related, structurally-diverse antimicrobials
10. Discovery and biological evaluation of 4,6-pyrimidine analogues with potential anticancer agents as novel colchicine binding site inhibitors
11. A paper-based assay for the colorimetric detection of SARS-CoV-2 variants at single-nucleotide resolution
12. Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor
13. Steric Hindrance-Mediated Enzymatic Reaction Enable Homogeneous Dual Fluorescence Indicators Aptasensing of Hepatocellular Carcinoma CTCs.
14. Self-Assembled DNA Machine and Selective Complexation Recognition Enable Rapid Homogeneous Portable Quantification of Lung Cancer CTCs
15. Single-Cell Liquid Biopsy of Lung Cancer: Ultra-Simplified Efficient Enrichment of Circulating Tumor Cells and Hand-Held Fluorometer Portable Testing
16. Label-free DNAzyme assays for dually amplified and one-pot detection of lead pollution
17. An alpine meadow soil chronology based on OSL and radiocarbon dating, Qinghai Lake, northeastern Tibetan Plateau
18. Study on air temperature estimation and its influencing factors in a complex mountainous area.
19. Finding representative sets of optimizations for adaptive multiversioning applications
20. The bromodomain protein BRD4 positively regulates necroptosis via modulating MLKL expression
21. Design, Synthesis, and Biological Evaluation of Dual Inhibitors of EGFRL858R/T790M/ACK1 to Overcome Osimertinib Resistance in Nonsmall Cell Lung Cancers.
22. X-ray crystal structure guided discovery of new selective, substrate-mimicking sirtuin 2 inhibitors that exhibit activities against non-small cell lung cancer cells
23. ((S)-3-Mercapto-2-methylpropanamido)acetic acid derivatives as metallo-β-lactamase inhibitors: Synthesis, kinetic and crystallographic studies
24. Inhibition of γ-glutamyl transferase suppresses airway hyperresponsiveness and airway inflammation in a mouse model of steroid resistant asthma exacerbation
25. X-ray Crystal Structure-Guided Discovery of Novel Indole Analogues as Colchicine-Binding Site Tubulin Inhibitors with Immune-Potentiating and Antitumor Effects against Melanoma
26. RSK inhibitors as potential anticancer agents: Discovery, optimization, and challenges
27. Design, Synthesis, and Antitumor Activity of Potent and Selective EGFR L858R/T790M Inhibitors and Identification of a Combination Therapy to Overcome Acquired Resistance in Models of Non-small-cell Lung Cancer
28. Design, Synthesis, and Biological Evaluation of Dual Inhibitors of EGFRL858R/T790M/ACK1 to Overcome Osimertinib Resistance in Nonsmall Cell Lung Cancers
29. Design, Synthesis, and Biological Evaluation of Heterocyclic-Fused Pyrimidine Chemotypes Guided by X-ray Crystal Structure with Potential Antitumor and Anti-multidrug Resistance Efficacy Targeting the Colchicine Binding Site
30. Rational design and crystallographic analysis of novel isoform-selective TRKA inhibitors for cancer therapy
31. The Ground Objects Identification for Digital Remote Sensing Image Based on the BP Neural Network
32. Long noncoding RNAs with peptide‐encoding potential identified in esophageal squamous cell carcinoma: KDM4A‐AS1‐encoded peptide weakens cancer cell viability and migratory capacity.
33. The Low Endometrial Expression of Long Non-Coding RNA NORAD Is Associated with Recurrent Pregnancy Losses and Unexplained Infertility
34. Two-Level Task Scheduling for Irregular Applications on GPU Platform
35. Improved CASA model based on satellite remote sensing data: simulating net primary productivity of Qinghai Lake basin alpine grassland
36. Global Tiling for Communication Minimal Parallelization on Distributed Memory Systems
37. Optimizing Packet Accesses for a Domain Specific Language on Network Processors
38. A Register Allocation Framework for Banked Register Files with Access Constraints
39. An Overview of the Open Research Compiler
40. Reply on RC2
41. The modified model code and the relevant data of gmd-2021-258
42. The Impacts of Bone Marrow Mesenchymal Stem Cells (BMSCs)-Derived Periostin on Epithelial-Mesenchymal Transition (EMT) of Cervical Cancer Cells
43. A luminescence dating study of loess deposits from the Yili River basin in western China
44. DCLK1 autoinhibition and activation in tumorigenesis
45. Supplementary material to "Improved CASA model based on satellite remote sensing data: Simulating net primary productivity of Qinghai Lake Basin alpine grassland"
46. Export of Dissolved Organic Carbon from the Source Region of Yangtze River in the Tibetan Plateau
47. Isothermal RNA Amplification for the Detection of Viable Pathogenic Bacteria to Estimate the Salmonella Virulence for Causing Enteritis
48. A distinct structure of Cas1–Cas2 complex provides insights into the mechanism for the longer spacer acquisition in Pyrococcus furiosus
49. Metal-induced G-quadruplex polymorphism for ratiometric and label-free detection of lead pollution in tea
50. The Ground Objects Identification for Digital Remote Sensing Image Based on the BP Neural Network
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