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4. Young age and adequate BCG are key factors for optimal BCG treatment efficacy in non-muscle-invasive bladder cancer

Author

Liu, Kang, Nicoletti, Rossella, Zhao, Hongda, Chen, Xuan, Wu, Hongwei, Leung, Chi-Ho, D’Andrea, David, Laukhtina, Ekaterina, Soria, Francesco, Gallioli, Andrea, Wroclawski, Marcelo Langer, Castellani, Daniele, Gauhar, Vineet, Rivas, Juan Gomez, Enikeev, Dmitry, Gontero, Paolo, Shariat, Shahrokh F., Chiu, Peter Ka-Fung, Ng, Chi-Fai, and Teoh, Jeremy Yuen-Chun

Published
2024
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10. Effects of a single epidural injection of low-dose esketamine on perioperative sedation and analgesia during cesarean section

Author

SUN Yufeng, TIAN Yanjiao, YANG Xiaolin, DING Ying, WU Hongwei, and YANG Chun

Subjects
esketamine, morphine, cesarean section, analgesia, sedation, epidural anesthesia, Medicine
Abstract

Objective To evaluate the analgesic and sedative effect of single epidural application of esketamine in cesarean section during perioperative period, and analyze the clinical application value of esketamine in cesarean section epidural analgesia and sedation. Methods From October 2021 to March 2022, 100 patients undergoing lower segment cesarean section under combined spinal epidural anesthesia in Rugao Hospital Affiliated to Nantong University were selected and randomly divided into morphine group (n=50) and esketamine group (n=50). After delivery of newborns (Apgar score ≥ 8) and removal of the umbilical placenta for 5 min, individuals in esketamine group were administered 20 mg ketamine, 5 mg dexamethasone plus 9 mg ropivacaine via an epidural catheter diluted with 0.9% sodium chloride to 6 mL; while individuals in morphine group were administered 2 mg morphine, 5 mg dexamethasone plus 9 mg ropivacaine via an epidural catheter, diluted with same volume (6 mL) of sodium chloride. The VAS score and Ramsay score at different time points after epidural administration, postoperative supplemental analgesic use and adverse reactions of the two groups were recorded. Results There was no significant difference between the two groups in VAS scores at 5 min after epidural administration, at the end of operation, 24 h after operation, and 48 h after operation, as well as the time of first use of supplementary analgesic drugs after operation and the proportion of the number of people (P＞0.05). At 5 min after epidural administration, Ramsay scores in esketamine group were significantly higher than those in morphine group (P＜0.05), and that there was no statistically difference in Ramsay scores between the two groups after surgery (P＞0.05). The incidence of dysuria (22.00% vs 4.00%, χ2=7.162, P＜0.05) and pruritus (18.00% vs 0, χ2=7.814, P＜0.05) in morphine group were higher than those in esketamine group. Conclusion Esketamine and morphine both exert effective analgesic effects during the perioperative period of cesarean section, and more importantly, ketamine is superior to morphine in sedative effect during cesarean section and reducing postoperative adverse reactions.

Published
2024
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15. Attention Augmented ConvNeXt UNet For Rectal Tumour Segmentation

Author

Wu, Hongwei, Wang, Junlin, Wang, Xin, Nan, Hui, Wang, Yaxin, Jing, Haonan, and Shi, Kaixuan

Subjects
Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Computer Vision and Pattern Recognition, Computer Science - Machine Learning
Abstract

It is a challenge to segment the location and size of rectal cancer tumours through deep learning. In this paper, in order to improve the ability of extracting suffi-cient feature information in rectal tumour segmentation, attention enlarged ConvNeXt UNet (AACN-UNet), is proposed. The network mainly includes two improvements: 1) the encoder stage of UNet is changed to ConvNeXt structure for encoding operation, which can not only integrate multi-scale semantic information on a large scale, but al-so reduce information loss and extract more feature information from CT images; 2) CBAM attention mechanism is added to improve the connection of each feature in channel and space, which is conducive to extracting the effective feature of the target and improving the segmentation accuracy.The experiment with UNet and its variant network shows that AACN-UNet is 0.9% ,1.1% and 1.4% higher than the current best results in P, F1 and Miou.Compared with the training time, the number of parameters in UNet network is less. This shows that our proposed AACN-UNet has achieved ex-cellent results in CT image segmentation of rectal cancer., Comment: I plan to replace this article, and supplement and confirm the structure and experimental content of this article

Published
2022

37. The quantale of order-preserving maps

Author

Wu, Hongwei

Subjects
Mathematics - Category Theory, Mathematics - Rings and Algebras, 06F07, 06B23, 18B35
Abstract

In this paper, two new composition operations are defined among the order-preserving maps. They can act on order-preserving maps like the usual composition operation. They are coincide with the usual composition operation when the order-preserving maps are sup-preserving maps or meet-preserving maps. The usual composition operation can't endow the set $L^{L}$ of order preserving maps on a complete lattices $L$ with quantale or co-quantale structures. Luckily, two new operations can endow $L^{L}$ with a quantale and a co-quantale structures respectively, whenever $L$ is a completely distributive lattice.

Published
2022

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