Search

Guided by the perspective that intimate relationship types represent a continuum of social attachment, we assessed how living apart together (LAT) relationships are related to psychological well-being in later life. Using data from the 2011 Wisconsin Longitudinal Study (WLS), we assessed levels of depressive symptoms by comparing LAT respondents (2.5%) with never married (2.5%), divorced (6.8%), widowed (10.4%), dating (2.8%), cohabiting (2.3%), remarried (15.1%), and first married (57.6%) men and women aged 51 and older (Total N = 7,924). However, the results did not support the theory of social attachment. The psychological well-being of men and women in LAT relationships was no different from either cohabiting or married adults. LAT relationships may have unique functions that help to reduce stress in later life. This study provides new insights about the psychological well-being of LAT adults. [ABSTRACT FROM AUTHOR]

Repeated claims that a dwindling supply of potential caregivers is creating a crisis in care for the U.S. aging population have not been well-grounded in empirical research. Concerns about the supply of family care do not adequately recognize factors that may modify the availability and willingness of family and friends to provide care to older persons in need of assistance or the increasing heterogeneity of the older population. In this paper, we set forth a framework that places family caregiving in the context of older adults' care needs, the alternatives available to them, and the outcomes of that care. We focus on care networks, rather than individuals, and discuss the demographic and social changes that may alter the formation of care networks in the future. Last, we identify research areas to prioritize in order to better support planning efforts to care for the aging U.S. population. [ABSTRACT FROM AUTHOR]

Rosa roxburghii f. eseiosa Ku is a variety of Rosa roxburghii, with two known genotypes: Wuci 1 and Wuci 2. The lack of prickle on the peel of R. roxburghii f. eseiosa makes it easy to pick and process, but its fruit size is small. Therefore, we aim to induce polyploidy in order to obtain a larger fruit variety of R. roxburghii f. eseiosa. In this study, current-year stems of Wuci 1 and Wuci 2 were used as materials for polyploid induction, which was carried out through colchicine treatment coupled with tissue culture and rapid propagation technology. Impregnation and smearing methods were effectively used to produce polyploids. Using flow cytometry and a chromosome counting method, it was found that one autotetraploid of Wuci 1 (2n = 4x = 28) was obtained by the impregnation method before primary culture, with a variation rate of 1.11%. Meanwhile, seven Wuci 2 bud mutation tetraploids (2n = 4x = 28) were produced by smearing methods during the training seedling stage. When tissue-culture seedlings were treated with 20 mg/L colchicine for 15 days, the highest polyploidy rate was up to 60%. Morphological differences between different ploidys were observed. The side leaflet shape index, guard cell length, and stomatal length of the Wuci 1 tetraploid were significantly different from those of the Wuci 1 diploid. The terminal leaflet width, terminal leaflet shape index, side leaflet length, side leaflet width, guard cell length, guard cell width, stomatal length, and stomatal width of the Wuci 2 tetraploid were significantly different from those of the Wuci 2 diploid. Additionally, the leaf color of the Wuci 1 and Wuci 2 tetraploids changed from light to dark, with an initial decrease in chlorophyll content followed by an increase. In summary, this study established an effective method for inducing polyploids in R. roxburghii f. eseiosa, which could provide a foundation for the breeding and development of new genetic resources for R. roxburghii f. eseiosa and other R. roxburghii varieties in the future. [ABSTRACT FROM AUTHOR]

Background: This study aimed to better characterize the clinicopathologic characteristics, outcomes, and prognostic factors of AITL in China. Methods: We retrospectively analyzed 312 patients with AITL enrolled between January 2011 and December 2020 from five institutions in China. Results: The median age was 65 years, with 92.6% advanced stage, 59.7% elevated LDH, 46.1% anemia, and 44.0% hypergammaglobulinemia. The majority of patients (84.9%) received anthracycline‐based regimens with or without etoposide, and only 6.1% underwent autologous stem cell transplantation following first remission. The 5‐year OS and PFS estimates were 43.4% and 25.0% with no significant improvement of survival between patients treated during 2011–2015 and 2016–2020, respectively. Both the International Prognostic Index (IPI) and the prognostic index for PTCL, not otherwise specified (PIT), were predictive for OS. In multivariate analysis, age >70 years, elevated LDH, and albumin level <35 g/L were independent prognostic factors for OS. Combining these three factors, a novel prognostic model (the Chinese AITL score) was constructed, which stratified patients into low‐, intermediate‐, and high‐risk groups, with 5‐year OS rates of 69.0%, 41.5%, and 23.7%, respectively. This new model was successfully validated in an independent cohort. Conclusions: Patients with AITL were mainly treated with anthracycline‐based regimens, and the outcomes were still unsatisfactory in China. Our novel prognostic model may improve our ability to identify patients at different risks for alternative therapies. [ABSTRACT FROM AUTHOR]

There is an ongoing debate over whether living apart together (LAT) relationships are simply long-term relationships or alternatives to cohabitation or marriage. This study examined cohabitation and marriage expectations among older adults who LAT in the United States to address the debate. The analyses also compared the marriage expectations of older adults who LAT and cohabitors. Using data from the 2011 Wisconsin Longitudinal Study (WLS), we examined the union expectations of 250 individuals who LAT and 234 cohabitors. After providing a demographic portrait of older adults who LAT, we used ordered logistic regression models to predict their cohabitation and marriage expectations. Additional models predicted marriage expectations for older adults who LAT versus cohabitors. Older adults who LAT were unlikely to expect to formalize their unions. Adults who LAT were less likely to expect marriage than cohabitors. LAT relationships appear to be long-term partnerships in the United States. [ABSTRACT FROM AUTHOR]