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To report the clinical features of cytomegalovirus (CMV) retinitis with panretinal occlusive vasculitis. Retrospective case series. Four eyes in 3 non-HIV patients (male: female = 3:0) were included. Previous medical history included diabetes mellitus (n = 2), age-related macular degeneration (n = 1), and Multiple myeloma under chemotherapy (n = 1). All patients were treated with oral valganciclovir and intravitreal ganciclovir. Slow resolution of retinitis related retinal opacification was noted in all 4 eyes. Two eyes had anti-viral agents discontinued despite the persistent retinitis related opacification and the lesions slowly resolved in the following months. The final decimal visual acuity was equal to or worse than 0.02 in 3 of the 4 eyes. In eyes of CMV retinitis with panretinal occlusive vasculitis, rapid resolution of retinitis lesions is an unreliable sign evaluating the therapeutic efficacy of anti-viral agents. Besides, despite treatment of anti-viral agents, deteriorating vascular occlusion may further endanger macular function. [ABSTRACT FROM AUTHOR]

Constructing an ecological security pattern by matching the supply and demand of ecosystem services is of great significance for Shenzhen, China. To determine the strategic positioning of sustainable development pioneers and benchmarks for human well-being in a pilot demonstration area of socialism with Chinese characteristics, we selected water yield, carbon sequestration, and recreational services to identifiy the integrated supply and demand status of ecosystem services in Shenzhen using the InVEST model, ecological supply-demand ratio, cell phone signalling data analysis, and circuit theory. An ecological security pattern based on the matching of supply and demand of ecosystem services was constructed. We further examined the impacts of different delimitation boundaries on the area and number of ecological sources. The results showed that the comprehensive ecological supply-demand ratio in Shenzhen generally showed a distribution pattern of abundant in the east and scarce in the west. Among them, water yield services met the demand in terms of quantity and spatial distribution, but carbon sequestration services can not. Recreational services met the demand in terms of quantity, but their spatial distribution was extremely uneven. We identified 25 ecological sources covering a total area of 347.62 km² and 34 ecological corridors with a total length of 346.06 km. The ecological source area was large in the east and small in the west, while the length of the corridors showed the opposite distribution pattern. Different delineation boundaries had different effects on the area and number of ecological sources. Primary, secondary, and tertiary ecological source areas cover 347.62, 520.84, and 557.58 km², respectively, showing a gradual increasing trend, the numbers of ecological sources were 25, 35, and 32, showing an increasing then decreasing trend. In Shenzhen, there were important ecological patches that were not included in the ecological control line, and some patches within the ecological control line had poor ecological sustainability. Targeted protection and management policies could be formulated based on such pattern. The results could provide spatial guidance for the delimitation of ecological management and control units in Shenzhen. [ABSTRACT FROM AUTHOR]