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Your search keyword '"Wu, Zhao-Xia"' showing total 41 results
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41 results on '"Wu, Zhao-Xia"'

2. ALDH2 and Cancer Therapy

Author

Wang, Li-Shun, Wu, Zhao-Xia, COHEN, IRUN R., Editorial Board Member, LAJTHA, ABEL, Editorial Board Member, LAMBRIS, JOHN D., Editorial Board Member, PAOLETTI, RODOLFO, Editorial Board Member, REZAEI, NIMA, Editorial Board Member, Ren, Jun, editor, Zhang, Yingmei, editor, and Ge, Junbo, editor

Published
2019
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5. Prevalence and risk factors for subjective cognitive decline and the correlation with objective cognition among community‐dwelling older adults in China: Results from the Hubei memory and aging cohort study

Author

Cheng, Gui‐Rong, primary, Liu, Dan, additional, Huang, Lin‐Ya, additional, Han, Gang‐Bin, additional, Hu, Fei‐Fei, additional, Wu, Zhao‐Xia, additional, He, Xiao‐Ming, additional, Huang, Yu‐Wei, additional, Yu, Ya‐Fu, additional, Xu, Lang, additional, Li, Jin‐Quan, additional, Chen, Yu‐Shan, additional, Wei, Zhen, additional, Wu, Qiong, additional, Mei, Yu‐Fei, additional, Chen, Xing‐Xing, additional, Ou, Yang‐Ming, additional, Zhang, Jing‐Jing, additional, Yang, Meng‐Liu, additional, Lian, Peng‐Fei, additional, Tan, Wei, additional, Xie, Xin‐Yan, additional, and Zeng, Yan, additional

Published
2023
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12. The Limit of Noether Conserved Charges is the Number of Primary First-Class Constraints in a Constrained System

Author

LU Wei-Tao, Pan Hong-Zhe, WU Zhao-Xia, Wang Yong-Long, Jiang Hua, and Chen Li

Subjects
symbols.namesake, Pure mathematics, Canonical variable, Physics and Astronomy (miscellaneous), Lagrange multiplier, Homogeneous space, symbols, Equations of motion, Noether's theorem, Hamiltonian (quantum mechanics), First class, Mathematics
Abstract

We discuss the stationarity of generator G for gauge symmetries in two directions. One is to the motion equations defined by total Hamiltonian HT, and gives that the number of the independent coefficients in the generator G is not greater than the number of the primary first-class constraints, and the number of Noether conserved charges is not greater than that of the primary first-class constraints, too. The other is to the variances of canonical variables deduced from the generator G, and gives the variances of Lagrangian multipliers contained in extended Hamiltonian HE. And a second-class constraint generated by a first-class constraint may imply a new first-class constraint which can be combined by introducing other second-class constraints. Finally, we supply two examples. One with three first-class constraints (two is primary and one is secondary) has two Noether conserved charges, and the secondary first-class constraint is combined by three second-class constraints which are a secondary and two primary second-class constraints. The other with two first-class constraints (one is primary and one is secondary) has one Noehter conserved charge.

Published
2012

13. VHL deficiency augments anthracycline sensitivity of clear cell renal cell carcinomas by down-regulating ALDH2

Author

Gao, Yao-Hui, primary, Wu, Zhao-Xia, additional, Xie, Li-Qi, additional, Li, Cai-Xia, additional, Mao, Yu-Qin, additional, Duan, Yan-Tao, additional, Han, Bing, additional, Han, San-Feng, additional, Yu, Yun, additional, Lu, Hao-Jie, additional, Yang, Peng-Yuan, additional, Xu, Tian-Rui, additional, Xia, Jing-Lin, additional, Chen, Guo-Qiang, additional, and Wang, Li-Shun, additional

Published
2017
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14. Phosphoproteomics Study on the Activated PKCδ-Induced Cell Death

Author

Xia, Li, Wang, Tong-Dan, Shen, Shao-Ming, Zhao, Meng, Sun, Han, He, Ying, Xie, Lu, Wu, Zhao-Xia, Han, San-Feng, Wang, Li-Shun, and Chen, Guo-Qiang

Abstract

The proteolytic activation of protein kinase Cδ (PKCδ) generates a catalytic fragment called PKCδ-CF, which induces cell death. However, the mechanisms underlying PKCδ-CF-mediated cell death are largely unknown. On the basis of an engineering leukemic cell line with inducible expression of PKCδ-CF, here we employ SILAC-based quantitative phosphoproteomics to systematically and dynamically investigate the overall phosphorylation events during cell death triggered by PKCδ-CF expression. Totally, 3000 phosphorylation sites were analyzed. Considering the fact that early responses to PKCδ-CF expression initiate cell death, we sought to identify pathways possibly related directly with PKCδ by further analyzing the data set of phosphorylation events that occur in the initiation stage of cell death. Interacting analysis of this data set indicates that PKCδ-CF triggers complicated networks to initiate cell death, and motif analysis and biochemistry verification reveal that several kinases in the downstream of PKCδ conduct these networks. By analysis of the specific sequence motif of kinase-substrate, we also find 59 candidate substrates of PKCδ from the up-regulated phosphopeptides, of which 12 were randomly selected for in vitrokinase assay and 9 were consequently verified as substrates of PKCδ. To our greatest understanding, this study provides the most systematic analysis of phosphorylation events initiated by the cleaved activated PKCδ, which would vastly extend the profound understanding of PKCδ-directed signal pathways in cell death. The MS data have been deposited to the ProteomeXchange with identifier PXD000225.

Published
2024
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38. The Flakt-Hydro process: flue gas desulfurisation by use of seawater

Author

Wu Zhao Xia

Subjects
Flue gas, Waste management, Power station, Chemistry, Environmental engineering, Management, Monitoring, Policy and Law, Pollution, Desulfurisation, chemistry.chemical_compound, Scientific method, Seawater, Sulfate, Waste Management and Disposal, Data scrubbing, Sulfur dioxide
Abstract

ABB's seawater scrubbing process (the Flakt-Hydro process) for flue gas desulfurisation has recently triggered much interest among power producers because of its simple operating principle and high reliability. The process uses seawater to absorb and neutralise sulfur dioxide in flue gases. The absorbed gas is oxidised and returned to the ocean in the form it originated in the first place, namely as dissolved sulfate salts. The process uses the seawater downstream of the power plant condensers. This paper gives an introduction to the basic principle of the process and presents some of the recent power plant applications, namely at the Paiton Private Power Project, Phase 1 (2 ∞ 670 Mwe) in Indonesia and at the Shenzhen West Power Plant, Unit 2 (300 MWe) in China.

Published
1999

39. [Effects of Yi Fu Ning soft gelatin capsules on reproductive endocrine-immune function of ovariectomized rats].

Author

Wu ZX, Wang XH, and Deng HZ

Subjects
Animals, Capsules, Curcuma chemistry, Drug Combinations, Drugs, Chinese Herbal therapeutic use, Female, Flow Cytometry, Follicle Stimulating Hormone blood, Hexestrol pharmacology, Hexestrol therapeutic use, Interleukin-2 blood, Materia Medica therapeutic use, Ovariectomy, Plants, Medicinal chemistry, Radioimmunoassay, Random Allocation, Rats, Rats, Sprague-Dawley, T-Lymphocyte Subsets drug effects, Drugs, Chinese Herbal pharmacology, Estradiol blood, Estrogens blood, Materia Medica pharmacology, T-Lymphocyte Subsets immunology
Abstract

Objective: To investigate the effect of Yi Fu Ning Soft Gelatin Capsules (YFN) on reproductive endocrine-immune function of ovariectomized rats., Methods: 60 3-month old female Sprague-Dawley rats were used, 50 of them were ovariectomized and randomly divided into 5 groups: ovariectomizy (OVX) group, OVX with diethylstilbestrol tablets (DT) group, OVX with YFN (high dose, middle dose and low dose) group. The others were sham-operated group. The rats were administrated initially in the 4th week after the operation. After drugs had been given for 12 weeks the rats were sacrificed, blood serum hormone, IL-2 content and T lymphocyte subpopulation were detected with methods radioimmunoassay and flow cytometry (FCM)., Results: (1) Compared with sham group, the level of serum E2, Te and P significantly decreased (P < 0.01), FSH, LH content significantly increased; Blood T lymphocyte subpopulation CD3+ cells, CD4+ cells and CD4+/CD8+ ratio significantly decreased, serum IL-2 content also significantly decreased (P < 0.01). (2) Compared with model group, after treated by YFN, the level of serum E2 and P significantly increased (P < 0.01), serum FSH and LH content significantly decreased; T lymphocyte subpopulation CD3+ cells, CD4+ cells and CD4+/CD8+ ratio were improved significantly and serum interleukin-2 (IL-2) content increased significantly., Conclusion: YFN can increase serum sexual hormone content,reduce the level of FSH and LH, and improve imbalanced T lymphocyte subpopulation, stimulate IL-2 excretion, which means YFN can regulate inordinate reproductive endocrine-immune network in ovariectomized rats.

Published
2009

40. [Effects of the mixture of Rhizoma Curcumae and Oviducts Ranae on estrogen and its receptor expressions in ovariectomized rats].

Author

Wu ZX, Wang XH, Liu H, and Deng HZ

Subjects
Animals, Drug Combinations, Female, Fluorescent Antibody Technique, Interleukin-2 blood, Ovariectomy, Radioimmunoassay, Rats, Rats, Sprague-Dawley, Spleen drug effects, Spleen metabolism, Curcuma chemistry, Drugs, Chinese Herbal pharmacology, Estrogens blood, Materia Medica pharmacology, Receptors, Estrogen metabolism
Abstract

Objective: To study the effect of the mixture of Rhizoma Curcumae (YFN) and Oviducts Ranae on serum estrogen and spleen estrogen receptor expressions and its effect on reproductive endocrine-immune network in ovariectomized (OVX) rats., Methods: Female SD rat models of climacteric syndrome (CS) were established by ovariectomy. After administration of YFN in the rats for 12 consecutive weeks, the serum estrogen levels (E2, FSH, LH, T, and P) and interleukin-2 were determined using radioimmunoassay, and the expression levels of estrogen receptor in the spleen were detected with immunofluorescence assay., Results: The serum E2, T, P, and interleukin-2 levels (P<0.01) and spleen estrogen receptor expression (P<0.05) were significantly increased after high-dose YFN administration in the OVX rats as compared with the levels in the untreated OVX rats. YFN also resulted in lowered serum FSH and LH levels, but the changes were not statistically significant., Conclusion: YFN can increase the serum estrogen levels and estrogen receptor expression in the spleen of OVX rats, suggesting its clinical potential for relieving CS.

Published
2008

41. [Expression of SARS spike gene in Shizomycete pombe].

Author

Wu ZX, Zheng WL, Zhang B, Shi YX, and Wen-Li

Subjects
Cloning, Molecular, Electroporation, Membrane Glycoproteins genetics, Recombinant Proteins genetics, Schizosaccharomyces genetics, Spike Glycoprotein, Coronavirus, Viral Envelope Proteins genetics, Membrane Glycoproteins biosynthesis, Recombinant Proteins biosynthesis, Severe acute respiratory syndrome-related coronavirus genetics, Schizosaccharomyces metabolism, Viral Envelope Proteins biosynthesis
Abstract

The viral spike protein is the main surface antigen of the coronavirus, and it could be useful in the research of clinical diagnosis, SARS vaccine and the structure biology.According to the analysis of the main antigen of the SARS spike protein, 5 fragments of the whole spike gene were cloned, and ligated to the vector pNMT1. Through electroporation transformantion to TCP1, the recombinant S. pombe strains capable of expressing the 5 fragments were constructed. SDS-PAGE or Western blot analysis of the induced expression products demonstrated that the 5 recombinant proteins were expressed in the fission yeast respectively.

Published
2005

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