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157 results on '"Xenos, Eleftherios S."'

2. Modes of Failure in Venous Thromboembolism Prophylaxis

Author

Richie, Cheryl D., primary, Castle, Jennifer T., additional, Davis, George A., additional, Bobadilla, Joseph L., additional, He, Qiang, additional, Moore, Mary B., additional, Kellenbarger, Tricia A., additional, and Xenos, Eleftherios S., additional

Published
2022
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30. Comparison of perioperative outcomes in endovascular versus open repair for juxtarenal and pararenal aortic aneurysms: A propensity-matched analysis.

Author

Orr, Nathan T., Davenport, Daniel L., Minion, David J., and Xenos, Eleftherios S.

Subjects
ABDOMINAL aortic aneurysms, BLOOD vessel prosthesis, CHI-squared test, COMPARATIVE studies, DATABASES, RESEARCH methodology, MEDICAL cooperation, PROBABILITY theory, RESEARCH, RISK assessment, SURGICAL complications, TIME, EVALUATION research, TREATMENT effectiveness, RETROSPECTIVE studies, ODDS ratio, EQUIPMENT & supplies
Abstract

Objective Endoluminal aortic aneurysm repair is suitable within certain anatomic specifications. This study aims to compare 30-day outcomes of endovascular versus open repairs for juxtarenal and pararenal aortic aneurysms (JAA/PAAs). Methods The ACS-NSQIP database was queried from 2012 to 2015 for JAA/PAA repairs. Procedures characterized as emergent were included in the study; however, failed prior repairs and ruptured aneurysms were excluded. The preoperative and perioperative patient characteristics, operative techniques, and outcome variables were compared between the open aortic repair and the endovascular aortic repair groups. Propensity scoring was performed to clinically match open aortic repair and endovascular aortic repair groups on preoperative risk and select perioperative factors that differed significantly in the unmatched groups. Outcome comparisons were then performed between matched groups. Results A total of 1005 (789 JAAs and 216 PAAs) aneurysm repairs were included in the study. Of these, there were 395 endovascular aortic repairs and 610 open aortic repairs. Propensity scoring created a matched group of 263 endovascular aortic repair and 263 open aortic repair patients. There was no statistically significant difference in 30-day mortality rates between matched endovascular aortic repair and open aortic repair patients (2.7% vs. 5.7%). The endovascular aortic repair group had a shorter ICU length of stay and overall hospital stay. The 30-day morbidity significantly favored endovascular aortic repair over open aortic repair (16% vs. 35%, p < 0.001). The main drivers of morbidity for endovascular aortic repair versus open aortic repair included return to the OR (6.8% vs. 15%, p < 0.001), rate of cardiac or respiratory failure (7.6% vs. 21%, p = 0.001), rate of renal insufficiency or failure (3.8% vs. 9.9%, p = 0.009), and rate of pneumonia (1.5% vs. 6.8%, p = 0.004). Conclusions There is no difference in mortality rates between endovascular aortic repair versus open aortic repair when repairing JAAs/PAAs. There is a significant difference in overall morbidity, and ICU and hospital length of stay favoring endovascular aortic repair over open aortic repair. This supports the expanded applicability and efficacy of endovascular repair for complex aneurysms. [ABSTRACT FROM AUTHOR]

Published
2017
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50. Type IIIb Endoleak Associated With an Infected Thoracoabdominal Endograft.

Author

Orr NT, Winkler MA, and Xenos ES

Subjects
Aortic Aneurysm, Abdominal surgery, Endovascular Procedures instrumentation, Humans, Male, Middle Aged, Prosthesis Failure, Reoperation, Treatment Outcome, Blood Vessel Prosthesis microbiology, Endoleak etiology, Endovascular Procedures adverse effects, Postoperative Hemorrhage diagnosis
Abstract

We present a 63-year-old male patient who presented with vague abdominal pain after an endoluminal thoracoabdominal aneurysm repair. He was found to have an infected endograft and an associated type IIIb endoleak. We believe that the infection contributed to the fabric degradation along the endograft and resulted in an expanding endoleak. Graft explantation was not performed because of the patient's multiple comorbidities, and the endoleak was treated with an additional stent graft and suppressive antibiotics. Endograft infection may lead to endograft degradation and associated leak. Therefore, an infectious etiology, although rare, should be considered when evaluating a delayed type IIIb endoleak.

Published
2016
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