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207 results on '"Xia, Harry Hua-Xiang"'

7. Machine learning algorithms based on proteomic data mining accurately predicting the recurrence of hepatitis B‐related hepatocellular carcinoma

Author

Feng, Gong, primary, He, Na, additional, Xia, Harry Hua‐Xiang, additional, Mi, Man, additional, Wang, Ke, additional, Byrne, Christopher D, additional, Targher, Giovanni, additional, Yuan, Hai‐Yang, additional, Zhang, Xin‐Lei, additional, Zheng, Ming‐Hua, additional, and Ye, Feng, additional

Published
2022
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10. Trends in treatments for prostate cancer in the United States, 2010-2015

Author

Wang, Jianwei, Xia, Harry Hua-Xiang, Zhang, Yuanyuan, and Zhang, Lanjing

Subjects
Original Article
Abstract

Although annual mortality trends for prostate cancer were stabilized in recent years, understanding the exact treatment changes is necessary for optimal management. Utilization of not-otherwise specified (NOS) treatments for prostate cancer was unclear. Thus, this study aimed to analyze trends in treatment for prostate cancer in the U.S. from 2010 to 2015 and examine whether the treatment for the prostate cancer in the U.S. is compliant with clinical practice guidelines. Using joinpoint regression models, we examined trends in the rate and proportion of age-standardized utilization (ASUR and ASUP) of treatments for prostate cancer diagnosed during 2010-2015 in the U.S. based on the data from the Surveillance, Epidemiology, and End Results (SEER, 2018 data-release, with linkage to active surveillance/watchful waiting [AS/WW]) cancer registry program. Among 316,690 men with prostate cancer diagnosed during 2010-2015, ASUR and ASUP for radical prostatectomy, radiotherapy, AS/WW and NOS treatment were 32.7, 34.4, 10.0 and 40.1 per 100,000, and 27.9%, 29.3%, 8.5% and 34.2%, respectively. Trends in the overall ASUR for prostate cancer treatments differed by cancer risk group, patients’ age, race/ethnicity, Gleason score, insurance status, and the average education level, average poverty-level and foreign-born person percentage of the patient’s residence-county, but not by rural-urban continuum or region. ASUP of radical prostatectomy decreased from 9.8% in 2010 to 4.8% in 2015 (annual percent change [APC] = -12.0%, 95% CI, -15.9 to -7.9%), and the decrease was observed in all different risk groups. ASUP of AS/WW increased from 16.4% in 2010 to 30.2% in 2013 (APC = 22.7%, 95% CI, 4.6 to 44.0%) and then remained stable through 2013 to 2015 (APC = 1.9%, 95% CI, -24.1 to 36.9%). The increasing tendency of AS/WW only occurred in the low-risk and intermediate-risk groups. The ASUP of NOS treatment has increased from 32.3% in 2010 to 36.8% in 2015 (P

Published
2021

15. Effects of Washed Microbiota Transplantation on Serum Uric Acid Levels, Symptoms, and Intestinal Barrier Function in Patients with Acute and Recurrent Gout: A Pilot Study.

Author

Xie, Wen-Rui, Yang, Xiao-Ya, Deng, Zhi-He, Zheng, Ya-Mei, Zhang, Ran, Wu, Li-Hao, Cai, Jie-Yi, Kong, Ling-Ping, Xia, Harry Hua-Xiang, and He, Xing-Xiang

Subjects
URIC acid, GOUT, FECAL microbiota transplantation, SHORT bowel syndrome, TUMOR lysis syndrome, INTESTINES, GUT microbiome
Abstract

Introduction: Gut dysbiosis has been reported to be closely associated with gout. Washed microbiota transplantation (WMT) is considered as an effective way to restore a healthy gut microbiota with less adverse events than the conventional fecal microbiota transplantation. In this study, we aimed to evaluate the effects of WMT on serum uric acid levels, symptoms, and the intestinal barrier function in patients with acute and recurrent gout. Methods: We performed a pilot study of WMT for acute and recurrent gout. The primary outcome was the changes in the serum uric acid level and gout symptoms. The secondary outcomes included the changes in levels of diamine oxidase (DAO), D-lactic acid, and endotoxin. Results: Eleven patients received WMT treatment. The averaged serum uric acid levels in patients with gout reduced after WMT (p = 0.031), accompanied with a decrease in the frequency and duration time of acute gout flares (p < 0.01). The levels of DAO, D-lactic acid, and endotoxin were higher in patients than in healthy donors (p < 0.05). After WMT treatment, the levels of DAO and endotoxin decreased (p < 0.05). Conclusions: WMT is effective for reducing serum uric acid levels and improving gout symptoms in patients with gout and contributes to improve their impaired intestinal barrier function. [ABSTRACT FROM AUTHOR]

Published
2022
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18. Effects of primary metronidazole and clarithromycin resistance to Helicobacter pylori on omeprazole, metronidazole, and clarithromycin triple-therapy regimen in a region with high rates of metronidazole resistance

Author

Wong, Wai Man, Gu, Qing, Wang, Wei Hong, Fung, Fiona Man-Yee, Berg, Douglas E., Lai, Kam Chuen, Xia, Harry Hua-Xiang, Hu, Wayne H.C., Chan, Chi Kuen, Chan, Annie On-On, Yuen, Man-Fung, Hui, Chee-Kin, Lam, Shiu Kum, and Wong, Benjamin Chun-Yu

Subjects
Statistics, Metronidazole -- Drug use, Drug resistance in microorganisms -- Research, Drug resistance in microorganisms -- Demographic aspects, Communicable diseases -- Research, Helicobacter infections -- Drug therapy, Health, Health care industry
Published
2003

41. Helicobacter pylori infection is associated with increased expression of macrophage migratory inhibitory factor--by epithelial cells, T cells, and macrophages--in gastric mucosa

Author

Xia, Harry Hua-Xiang, Lam, Shiu-Kum, Huang, Xiao-Ru, Wong, Wai-Man, Leung, Suet-Yi, Yuen, Siu-Tsan, Lan, Hui-Yao, and Wong, Benjamin Chun-Yu

Subjects
Macrophages -- Research, T cells -- Health aspects, T cells -- Research, Epithelial cells -- Health aspects, Epithelial cells -- Research, Helicobacter infections -- Care and treatment, Helicobacter infections -- Research, Health
Published
2004

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