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18 results on '"Xia, Yali"'

4. Ergonomic study of partial lighting

Author

KIIMA, Miku, primary, KOZA, Yuma, additional, SATO, Shuho, additional, NAKAMURA, Nanako, additional, TOKAIRIN, Ayano, additional, KOBAYASHI, Haruhi, additional, MIYAMOTO, Nanaka, additional, SHIMOMURA, Yoshihiro, additional, XIA, Yali, additional, and UENO, Takeshi, additional

Published
2022
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7. Relationship between anxiety and monotonous task performance in response to local cooling: an experimental study in healthy young men.

Author

Xia, Yali and Shimomura, Yoshihiro

Subjects
ANXIETY prevention, PREVENTION of psychological stress, INDUCED hypothermia, STATE-Trait Anxiety Inventory, AROUSAL (Physiology), ELECTROENCEPHALOGRAPHY, TASK performance, PSYCHOLOGICAL tests, STRESS management, ANXIETY, PSYCHOLOGICAL stress, COLD (Temperature)
Abstract

There are limited studies on monotonous task performance and its relationship with anxiety and stress traits. This study aimed to determine if local cooling exerts physiological effects and positively affects task performance. Ten male participants performed monotonous work for 24 min under control and local cooling conditions. We measured physiological arousal and anxiety using electroencephalography and the State-Trait Anxiety Inventory, respectively. The participants rated their drowsiness, the thermal sensation of the seat and whole-body thermal sensation. Despite the lack of significant differences in physiological arousal, the state anxiety score, which reflects the current stressful situation, was significantly lower in the local cooling condition. Therefore, cooling might help relieve stress during monotonous tasks, without impairing task performance. In addition, individuals with higher state anxiety scores tended to experience a faster increase in their arousal level. Thus, individual anxiety traits may modulate attentional resources during monotonous task performance. Practitioner summary: The study on topic related to monotonous task performance and its relationship with anxiety and stress traits is novel. Minimising negative emotions is key to monotonous task execution under stress. Individual anxiety might modulate resource allocation for monotonous task execution. [ABSTRACT FROM AUTHOR]

Published
2023
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18. MicroRNA-2861 targets STAT3 and MMP2 to regulate the proliferation and apoptosis of ectopic endometrial cells in endometriosis

Author

Yu, Hao, Zhong, Qun, Xia, Yali, Li, Enchun, Wang, Shufang, and Ren, Rong

Abstract

This study aimed to elucidate the roles and regulatory mechanism of miR-2861 in the development of endometriosis. The expression of miR-2861 in endometriotic tissues and eutopic endometrial tissues was determined. Ectopic endometrial cells were transfected with miR-2861 mimic, miR-2861 inhibitor and their corresponding controls. The effects of miR-2861 overexpression and inhibition on cell proliferation and apoptosis were then investigated. In addition, regulatory relationship between miR-2681 and signal transducer and activator of transcription 3 (STAT3) or matrix metalloproteinase 2 (MMP2) was explored, as well as between STAT3 and MMP2. Compared with eutopic endometrial tissues, miR-2861 was significantly downregulated in endometriotic tissues. Overexpression of miR-2861 markedly inhibited ectopic endometrial cell proliferation and induced apoptosis. Additionally, STAT3 and MMP2 were confirmed as the targets of miR-2861, and the effects of knockdown of STAT3 or MMP2on regulating cell proliferation and apoptosis were opposite with inhibition of miR-2861. Besides, STAT3 could enhance the expression of MMP2 in ectopic endometrial cells. Our study reveals that miR-2861 was lowly expressed in endometriotic tissues, and downregulation of miR-2861 may promote proliferation and inhibit apoptosis of ectopic endometrial cells in endometriosisviaupregulation of STAT3 and MMP2. miR-2861 may be a potential biomarker or therapeutic target for endometriosis.

Published
2019
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