17 results on '"Xiangyu Ou"'
Search Results
2. A Perovskite-Based Paper Microfluidic Sensor for Haloalkane Assays
- Author
-
Lili Xie, Jie Zan, Zhijian Yang, Qinxia Wu, Xiaofeng Chen, Xiangyu Ou, Caihou Lin, Qiushui Chen, and Huanghao Yang
- Subjects
colorimetric ,microfluidic ,anion exchange ,perovskite ,haloalkanes ,Chemistry ,QD1-999 - Abstract
Detection of haloalkanes is of great industrial and scientific importance because some haloalkanes are found serious biological and atmospheric issues. The development of a flexible, wearable sensing device for haloalkane assays is highly desired. Here, we develop a paper-based microfluidic sensor to achieve low-cost, high-throughput, and convenient detection of haloalkanes using perovskite nanocrystals as a nanoprobe through anion exchanging. We demonstrate that the CsPbX3 (X = Cl, Br, or I) nanocrystals are selectively and sensitively in response to haloalkanes (CH2Cl2, CH2Br2), and their concentrations can be determined as a function of photoluminescence spectral shifts of perovskite nanocrystals. In particular, an addition of nucleophilic trialkyl phosphines (TOP) or a UV-photon-induced electron transfer from CsPbX3 nanocrystals is responsible for achieving fast sensing of haloalkanes. We further fabricate a paper-based multichannel microfluidic sensor to implement fast colorimetric assays of CH2Cl2 and CH2Br2. We also demonstrate a direct experimental observation on chemical kinetics of anion exchanging in lead-halide perovskite nanocrystals using a slow solvent diffusion strategy. Our studies may offer an opportunity to develop flexible, wearable microfluidic sensors for haloalkane sensing, and advance the in-depth fundamental understanding of the physical origin of anion-exchanged nanocrystals.
- Published
- 2021
- Full Text
- View/download PDF
3. Recent Development in X-Ray Imaging Technology: Future and Challenges
- Author
-
Xiangyu Ou, Xue Chen, Xianning Xu, Lili Xie, Xiaofeng Chen, Zhongzhu Hong, Hua Bai, Xiaowang Liu, Qiushui Chen, Lin Li, and Huanghao Yang
- Subjects
Science - Abstract
X-ray imaging is a low-cost, powerful technology that has been extensively used in medical diagnosis and industrial nondestructive inspection. The ability of X-rays to penetrate through the body presents great advances for noninvasive imaging of its internal structure. In particular, the technological importance of X-ray imaging has led to the rapid development of high-performance X-ray detectors and the associated imaging applications. Here, we present an overview of the recent development of X-ray imaging-related technologies since the discovery of X-rays in the 1890s and discuss the fundamental mechanism of diverse X-ray imaging instruments, as well as their advantages and disadvantages on X-ray imaging performance. We also highlight various applications of advanced X-ray imaging in a diversity of fields. We further discuss future research directions and challenges in developing advanced next-generation materials that are crucial to the fabrication of flexible, low-dose, high-resolution X-ray imaging detectors.
- Published
- 2021
- Full Text
- View/download PDF
4. High-resolution X-ray luminescence extension imaging
- Author
-
Zhigao Yi, Xiaogang Liu, Zhongzhu Hong, Juan Li, Xian Qin, Xiangyu Ou, Yiming Wu, Bolong Huang, Jie Zan, Lili Xie, Qinxia Wu, Huanghao Yang, Hongyu Bian, Xiaofeng Chen, Qiushui Chen, and Xiaorong Song
- Subjects
Multidisciplinary ,Materials science ,Silicon ,business.industry ,Detector ,Resolution (electron density) ,chemistry.chemical_element ,Photodetector ,02 engineering and technology ,Electron ,Radioluminescence ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,chemistry ,Optoelectronics ,0210 nano-technology ,business ,Luminescence ,Quantum - Abstract
Current X-ray imaging technologies involving flat-panel detectors have difficulty in imaging three-dimensional objects because fabrication of large-area, flexible, silicon-based photodetectors on highly curved surfaces remains a challenge1–3. Here we demonstrate ultralong-lived X-ray trapping for flat-panel-free, high-resolution, three-dimensional imaging using a series of solution-processable, lanthanide-doped nanoscintillators. Corroborated by quantum mechanical simulations of defect formation and electronic structures, our experimental characterizations reveal that slow hopping of trapped electrons due to radiation-triggered anionic migration in host lattices can induce more than 30 days of persistent radioluminescence. We further demonstrate X-ray luminescence extension imaging with resolution greater than 20 line pairs per millimetre and optical memory longer than 15 days. These findings provide insight into mechanisms underlying X-ray energy conversion through enduring electron trapping and offer a paradigm to motivate future research in wearable X-ray detectors for patient-centred radiography and mammography, imaging-guided therapeutics, high-energy physics and deep learning in radiology. Using lanthanide-doped nanomaterials and flexible substrates, an approach that enables flat-panel-free, high-resolution, three-dimensional imaging is demonstrated and termed X-ray luminescence extension imaging.
- Published
- 2021
5. Organic phosphors with bright triplet excitons for efficient X-ray-excited luminescence
- Author
-
Yu Wang, He Wang, Guohui Yang, Chongyang Lin, Jie Zan, Yang Michael Yang, Xiaokang Yao, Jiahuan Zhi, Huanghao Yang, Qiushui Chen, Huifang Shi, Xiangyu Ou, Zhu Zhao, Wenyong Jia, Jianpu Wang, Xueyan Jiang, Guoqing Zhang, Wenpeng Ye, Huili Ma, Xiaoji Xie, Manjeet Singh, Qian Wang, Xiaogang Liu, Chaomin Dong, Zhongfu An, Wei Huang, Xiao Wang, Lulu Song, and Yong'an Tang
- Subjects
Materials science ,business.industry ,Exciton ,Phosphor ,02 engineering and technology ,Radioluminescence ,Scintillator ,021001 nanoscience & nanotechnology ,01 natural sciences ,Atomic and Molecular Physics, and Optics ,Particle detector ,Electronic, Optical and Magnetic Materials ,010309 optics ,visual_art ,Excited state ,0103 physical sciences ,visual_art.visual_art_medium ,Optoelectronics ,Ceramic ,0210 nano-technology ,Luminescence ,business - Abstract
Materials that exhibit X-ray-excited luminescence have great potential in radiation detection, security inspection, biomedical applications and X-ray astronomy1–5. However, high-performance materials are almost exclusively limited to ceramic scintillators, which are typically prepared under high temperatures6. Herein we report metal-free organic phosphors based on a molecular design that supports efficient triplet exciton harvesting to enhance radioluminescence. These organic scintillators exhibit a detection limit of 33 nGy s–1, which is 167 times lower than the standard dosage for X-ray medical examination and we demonstrate their potential application in X-ray radiography. These findings provide a fundamental design principle and new route for the creation of promising alternatives to incumbent inorganic scintillators. Furthermore, they offer new opportunities for development of flexible, stretchable X-ray detectors and imagers for non-destructive radiography testing and medical imaging. Organic, metal-free materials that act as efficient X-ray scintillators could bring new opportunities for X-ray imaging.
- Published
- 2021
6. Organic Semiconductor Single Crystals for X-ray Imaging
- Author
-
Wenping Hu, Huanli Dong, Xiangfeng Duan, Mingxi Chen, Xiaogang Liu, Xiangyu Ou, Lingjie Sun, and Huanghao Yang
- Subjects
Materials science ,business.industry ,Mechanical Engineering ,Resolution (electron density) ,X-ray ,New materials ,Radioluminescence ,Metal ,Organic semiconductor ,Radiography ,Mechanics of Materials ,visual_art ,visual_art.visual_art_medium ,Optoelectronics ,General Materials Science ,Irradiation ,business ,Ultrashort pulse - Abstract
Low-dose, high-resolution X-ray imaging is vital for medical diagnostics and material/device analyses. Current X-ray imagers are dominated by expensive inorganic materials via high-temperature solid processes (up to 1700 °C, e.g., CsI:Tl) with heavy metal elements. It is essential to search for new materials as X-ray imagers with low growth temperature, low cost, high sensitivity, along with high chemical and environmental stability. Here, 9,10-diphenylanthracene (9,10-DPA) single crystals are used as a representative model, which are grown via low-temperature solution processes, exhibiting intense X-ray radioluminescence with ultrahigh photon-conversion efficiency, ultrafast response and high sensitivity. The resolution of devices based on organic crystals exceeds 20.00 lp mm-1 . Meanwhile the crystals exhibit high cycle performance under X-ray irradiation and environmental stability. This study demonstrates that organic semiconductors have potential use in low-cost, high-sensitivity and low-dose X-ray imaging systems.
- Published
- 2021
7. A Perovskite-Based Paper Microfluidic Sensor for Haloalkane Assays
- Author
-
Huanghao Yang, Jie Zan, Qinxia Wu, Xiaofeng Chen, Lili Xie, Qiushui Chen, Caihou Lin, Zhijian Yang, and Xiangyu Ou
- Subjects
Photoluminescence ,Materials science ,Haloalkane ,Wearable sensing ,Microfluidics ,microfluidic ,Nanoprobe ,Nanotechnology ,02 engineering and technology ,010402 general chemistry ,01 natural sciences ,colorimetric ,Electron transfer ,anion exchange ,haloalkanes ,QD1-999 ,perovskite ,Original Research ,Perovskite (structure) ,chemistry.chemical_classification ,General Chemistry ,021001 nanoscience & nanotechnology ,0104 chemical sciences ,Chemistry ,chemistry ,Nanocrystal ,0210 nano-technology - Abstract
Detection of haloalkanes is of great industrial and scientific importance because some haloalkanes are found serious biological and atmospheric issues. The development of a flexible, wearable sensing device for haloalkane assays is highly desired. Here, we develop a paper-based microfluidic sensor to achieve low-cost, high-throughput, and convenient detection of haloalkanes using perovskite nanocrystals as a nanoprobe through anion exchanging. We demonstrate that the CsPbX3 (X = Cl, Br, or I) nanocrystals are selectively and sensitively in response to haloalkanes (CH2Cl2, CH2Br2), and their concentrations can be determined as a function of photoluminescence spectral shifts of perovskite nanocrystals. In particular, an addition of nucleophilic trialkyl phosphines (TOP) or a UV-photon-induced electron transfer from CsPbX3 nanocrystals is responsible for achieving fast sensing of haloalkanes. We further fabricate a paper-based multichannel microfluidic sensor to implement fast colorimetric assays of CH2Cl2 and CH2Br2. We also demonstrate a direct experimental observation on chemical kinetics of anion exchanging in lead-halide perovskite nanocrystals using a slow solvent diffusion strategy. Our studies may offer an opportunity to develop flexible, wearable microfluidic sensors for haloalkane sensing, and advance the in-depth fundamental understanding of the physical origin of anion-exchanged nanocrystals.
- Published
- 2021
8. Synthesis of Copper Peroxide Nanodots for H2O2 Self-Supplying Chemodynamic Therapy
- Author
-
Jun-Feng Wang, Sheng Wang, Zhangtong Wang, Zijian Zhou, Xiaoyuan Chen, Jibin Song, Huanghao Yang, Xiangyu Ou, Hongzhang Deng, Gang Niu, Yuan Liu, Tao Huang, Yijing Liu, Rui Tian, Lisen Lin, and Guocan Yu
- Subjects
inorganic chemicals ,General Chemistry ,010402 general chemistry ,Endocytosis ,01 natural sciences ,Biochemistry ,Combinatorial chemistry ,Peroxide ,Catalysis ,0104 chemical sciences ,Lipid peroxidation ,chemistry.chemical_compound ,Colloid and Surface Chemistry ,chemistry ,Copper peroxide ,Hydroxide ,Hydroxyl radical ,Nanodot - Abstract
Chemodynamic therapy (CDT) employs Fenton catalysts to kill cancer cells by converting intracellular H2O2 into hydroxyl radical (•OH), but endogenous H2O2 is insufficient to achieve satisfactory anticancer efficacy. Despite tremendous efforts, engineering CDT agents with specific and efficient H2O2 self-supplying ability remains a great challenge. Here, we report the fabrication of copper peroxide (CP) nanodot, which is the first example of a Fenton-type metal peroxide nanomaterial, and its use as an activatable agent for enhanced CDT by self-supplying H2O2. The CP nanodots were prepared through coordination of H2O2 to Cu2+ with the aid of hydroxide ion, which could be reversed by acid treatment. After endocytosis into tumor cells, acidic environment of endo/lysosomes accelerated the dissociation of CP nanodots, allowing simultaneous release of Fenton catalytic Cu2+ and H2O2 accompanied by a Fenton-type reaction between them. The resulting •OH induced lysosomal membrane permeabilization through lipid peroxidation and thus caused cell death via a lysosome-associated pathway. In addition to pH-dependent •OH generation property, CP nanodots with small particle size showed high tumor accumulation after intravenous administration, which enabled effective tumor growth inhibition with minimal side effects in vivo. Our work not only provides the first paradigm for fabricating Fenton-type metal peroxide nanomaterials, but also presents a new strategy to improve CDT efficacy.
- Published
- 2019
9. Flexible X-ray luminescence imaging enabled by cerium-sensitized nanoscintillators
- Author
-
Xiaokun Li, Qiushui Chen, Zhongzhu Hong, Xiaoze Wang, Zhijian Yang, Xiangyu Ou, Hao Jiang, Xiaofeng Chen, Yu He, Huanghao Yang, and Xiaoling Chen
- Subjects
Materials science ,Passivation ,business.industry ,Biophysics ,chemistry.chemical_element ,General Chemistry ,Radioluminescence ,Scintillator ,Condensed Matter Physics ,Biochemistry ,Atomic and Molecular Physics, and Optics ,Energy quenching ,Cerium ,Nanocrystal ,chemistry ,Optoelectronics ,Luminescence ,Absorption (electromagnetic radiation) ,business - Abstract
: Colloidal nanocrystal scintillators hold great potential in fabricating large-area, flexible X-ray detectors for high-resolution X-ray imaging of highly curved, irregularly shaped objects. The synthesis of high-efficiency, high-stability nanoscintillators is of great importance for the development of X-ray imaging detectors. In this study, we develop a class of cerium (Ce3+)-sensitized core-shell nanoscintillators that are suitable for achieving flexible X-ray luminescence imaging. We demonstrate that an epitaxial growth of NaGdF4:Ce(60%) on the surface of NaGdF4:Eu(15%) nanoscintillators as a sensitization layer allows for enhancing X-ray-induced radioluminescence. We reveal that the enhancement of X-ray luminescence in nanoscintillators could be attributed to the synergistic effect of high-Z composition-induced X-ray absorption, Ce3+ sensitization, and surface passivation to relieve energy quenching. By incorporating the nanoscintillators into a flexible elastomer of polydimethylsiloxane (PDMS), we demonstrate its utility in high-resolution flexible X-ray luminescence imaging.
- Published
- 2022
10. Bright triplet excitons for efficient X-ray excited luminescence
- Author
-
Zhu Zhao, Xiaokang Yao, Jiahuan Zhi, Jie Zan, Wenpeng Ye, Yu Wang, Xiao Wang, Wenyong Jia, Huili Ma, Chongyang Lin, Qiushui Chen, Lulu Song, Huifang Shi, Wei Huang, Yang Yang, Xueyan Jiang, Guoqing Zhang, He Wang, Zhongfu An, Xiaoji Xie, Manjeet Singh, Qian Wang, Xiaogang Liu, Guohui Yang, Jianpu Wang, Chaomin Dong, Xiangyu Ou, Huanghao Yang, and Yong'an Tang
- Subjects
Materials science ,Excited state ,Exciton ,X-ray ,Atomic physics ,Luminescence - Abstract
Materials that exhibit X-ray excited luminescence have great potential in radiation detection, security inspection, biomedical applications, and X-ray astronomy1-4. However, such materials are almost exclusively limited to inorganic crystals, which are typically prepared under high temperatures5. Herein, we report a design principle of purely organic phosphors to boost X-ray excited luminescence with sufficient utilization of triplet excitons. Our experimental data reveal that proportion of emission from bright triplet excitons is significantly improved upon X-ray irradiation, compared with UV excitation. These organic phosphors have a detection limit of 33 nGy/s, which is 167 times lower than the standard dosage for X-ray medical examinations. We further demonstrated their potential application in X-ray radiography, which can be conveniently recorded using a digital camera. These findings illustrate a fundamental principle to design efficient X-ray excited purely organic phosphors, propelling the development of radioluminescence related applications.
- Published
- 2020
11. High-resolution X-ray luminescence extension imaging
- Author
-
Xiangyu, Ou, Xian, Qin, Bolong, Huang, Jie, Zan, Qinxia, Wu, Zhongzhu, Hong, Lili, Xie, Hongyu, Bian, Zhigao, Yi, Xiaofeng, Chen, Yiming, Wu, Xiaorong, Song, Juan, Li, Qiushui, Chen, Huanghao, Yang, and Xiaogang, Liu
- Abstract
Current X-ray imaging technologies involving flat-panel detectors have difficulty in imaging three-dimensional objects because fabrication of large-area, flexible, silicon-based photodetectors on highly curved surfaces remains a challenge
- Published
- 2020
12. Broadband Detection of X‐ray, Ultraviolet, and Near‐Infrared Photons using Solution‐Processed Perovskite–Lanthanide Nanotransducers
- Author
-
Huanghao Yang, Juan Li, Qiushui Chen, Jie Zan, Qinxia Wu, Xiaofeng Chen, Zhijian Yang, Yu He, Zhongzhu Hong, Xiangyu Ou, Xiaorong Song, and Lili Xie
- Subjects
Lanthanide ,Materials science ,Photon ,business.industry ,Mechanical Engineering ,Near-infrared spectroscopy ,Photodetector ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,medicine.disease_cause ,01 natural sciences ,Photon upconversion ,0104 chemical sciences ,Mechanics of Materials ,medicine ,Optoelectronics ,General Materials Science ,0210 nano-technology ,business ,Absorption (electromagnetic radiation) ,Ultraviolet ,Perovskite (structure) - Abstract
Solution-processed metal-halide perovskites hold great promise in developing next-generation low-cost, high-performance photodetectors. However, the weak absorption of perovskites beyond the near-infrared spectral region posts a stringent limitation on their use for broadband photodetectors. Here, the rational design and synthesis of an upconversion nanoparticles (UCNPs)-perovskite nanotransducer are presented, namely UCNPs@mSiO2 @MAPbX3 (X = Cl, Br, or I), for broadband photon detection spanning from X-rays, UV, to NIR. It is demonstrated that, by in situ crystallization and deliberately tuning the material composition in the lanthanide core and perovskites, the nanotransducers allow for a high stability and show a wide linear response to X-rays of various dose rates, as well as UV/NIR photons of various power densities. The findings provide an opportunity to explore the next-generation broadband photodetectors in the field of high-quality imaging and optoelectronic devices.
- Published
- 2021
13. Metal Halide Perovskite Nanosheet for X-ray High-Resolution Scintillation Imaging Screens
- Author
-
Yuchong Ding, Omar F. Mohammed, Osman M. Bakr, Lingmei Liu, Anton V. Malko, Xiaogang Liu, Kaifang Fu, Yuhai Zhang, Huanghao Yang, Yu Han, Xiangyu Ou, Liang-Jin Xu, Ruijia Sun, Qiushui Chen, and Hong Liu
- Subjects
Scintillation ,Fabrication ,Materials science ,Silicon ,Physics::Instrumentation and Detectors ,business.industry ,General Engineering ,X-ray ,General Physics and Astronomy ,chemistry.chemical_element ,02 engineering and technology ,Radioluminescence ,Scintillator ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,chemistry ,Quantum dot ,Optoelectronics ,General Materials Science ,0210 nano-technology ,business ,Nanosheet - Abstract
Scintillators, which are capable of converting ionizing radiation into visible photons, are an integral part of medical, security, and commercial diagnostic technologies such as X-ray imaging, nuclear cameras, and computed tomography. Conventional scintillator fabrication typically involves high-temperature sintering, generating agglomerated powders or large bulk crystals, which pose major challenges for device integration and processability. On the other hand, colloidal quantum dot scintillators cannot be cast into compact solid films with the necessary thickness required for most X-ray applications. Here, we report the room-temperature synthesis of a colloidal scintillator comprising CsPbBr3 nanosheets of large concentration (up to 150 mg/mL). The CsPbBr3 colloid exhibits a light yield (∼21000 photons/MeV) higher than that of the commercially available Ce:LuAG single-crystal scintillator (∼18000 photons/MeV). Scintillators based on these nanosheets display both strong radioluminescence (RL) and long-term stability under X-ray illumination. Importantly, the colloidal scintillator can be readily cast into a uniform crack-free large-area film (8.5 × 8.5 cm2 in area) with the requisite thickness for high-resolution X-ray imaging applications. We showcase prototype applications of these high-quality scintillating films as X-ray imaging screens for a cellphone panel and a standard central processing unit chip. Our radiography prototype combines large-area processability with high resolution and a strong penetration ability to sheath materials, such as resin and silicon. We reveal an energy transfer process inside those stacked nanosheet solids that is responsible for their superb scintillation performance. Our findings demonstrate a large-area solution-processed scintillator of stable and efficient RL as a promising approach for low-cost radiography and X-ray imaging applications.
- Published
- 2019
14. Autofluorescence-Free Immunoassay Using X-ray Scintillating Nanotags
- Author
-
Jingying Li, Juan Li, Qi-Zhao Zhang, Xiangyu Ou, Han-Yu Liang, Liang Song, Guo Tao, Huanghao Yang, and Jia-Qi Liao
- Subjects
Luminescent Measurements ,Surface Properties ,Injections, Subcutaneous ,Mice, Nude ,02 engineering and technology ,010402 general chemistry ,01 natural sciences ,Fluorescence ,Analytical Chemistry ,Mice ,Animals ,Humans ,Particle Size ,Absorption (electromagnetic radiation) ,Cells, Cultured ,Immunoassay ,Quenching (fluorescence) ,Chemistry ,business.industry ,X-Rays ,Optical Imaging ,Neoplasms, Experimental ,021001 nanoscience & nanotechnology ,0104 chemical sciences ,Autofluorescence ,Optoelectronics ,Nanoparticles ,alpha-Fetoproteins ,0210 nano-technology ,business ,Luminescence ,Biosensor ,Biomarkers ,Visible spectrum - Abstract
Autofluorescence background in complex biological samples is a major challenge in achieving high sensitivity of fluorescence immunoassays (FIA). Here we report an X-ray luminescence-based immunoassay for high-sensitivity detection of biomarkers using X-ray scintillating nanotags. Due to the weak scattering and absorption of most biological chromophores by X-ray excitation, a low-dose X-ray source can be used to produce intense scintillating luminescence from the nanotags for autofluorescence-free biosensing. To demonstrate this concept, we designed and synthesized NaGdF4:Tb@NaYF4 core/shell nanoparticles as kind of high-efficiency X-ray scintillating nanotags, which are able to convert high-energy X-ray photons to visible light without autofluorescence in biological samples. Notably, strong X-ray absorption and minimized surface quenching arising from the heavy Gd3+/Tb3+ atoms and core/shell architecture of the nanoparticles were found to be critically important for high-efficiency X-ray excited luminesce...
- Published
- 2018
15. All-inorganic perovskite nanocrystal scintillators
- Author
-
Xiaoji Xie, Tom Wu, Huanghao Yang, Xiaogang Liu, Zhigao Yi, Jawaher Almutlaq, Sanyang Han, Xinwei Guan, Ying Li, Liangliang Liang, Osman M. Bakr, Wei Huang, Qiushui Chen, Daniel Boon Loong Teh, Omar F. Mohammed, Jing Wu, Angelo H. All, Dianyuan Fan, Xiangyu Ou, Yu Wang, Marco Bettinelli, Juan Li, Ayan A. Zhumekenov, and Bolong Huang
- Subjects
Multidisciplinary ,Materials science ,business.industry ,chemistry.chemical_element ,02 engineering and technology ,Radioluminescence ,Scintillator ,X-RAY-DETECTORS ,SINGLE-CRYSTALS ,LARGE-AREA ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,Nanocrystal ,chemistry ,Caesium ,Optoelectronics ,Irradiation ,0210 nano-technology ,Absorption (electromagnetic radiation) ,business ,Perovskite (structure) ,Visible spectrum - Abstract
The rising demand for radiation detection materials in many applications has led to extensive research on scintillators1–3. The ability of a scintillator to absorb high-energy (kiloelectronvolt-scale) X-ray photons and convert the absorbed energy into low-energy visible photons is critical for applications in radiation exposure monitoring, security inspection, X-ray astronomy and medical radiography4,5. However, conventional scintillators are generally synthesized by crystallization at a high temperature and their radioluminescence is difficult to tune across the visible spectrum. Here we describe experimental investigations of a series of all-inorganic perovskite nanocrystals comprising caesium and lead atoms and their response to X-ray irradiation. These nanocrystal scintillators exhibit strong X-ray absorption and intense radioluminescence at visible wavelengths. Unlike bulk inorganic scintillators, these perovskite nanomaterials are solution-processable at a relatively low temperature and can generate X-ray-induced emissions that are easily tunable across the visible spectrum by tailoring the anionic component of colloidal precursors during their synthesis. These features allow the fabrication of flexible and highly sensitive X-ray detectors with a detection limit of 13 nanograys per second, which is about 400 times lower than typical medical imaging doses. We show that these colour-tunable perovskite nanocrystal scintillators can provide a convenient visualization tool for X-ray radiography, as the associated image can be directly recorded by standard digital cameras. We also demonstrate their direct integration with commercial flat-panel imagers and their utility in examining electronic circuit boards under low-dose X-ray illumination. All-inorganic perovskite nanocrystals containing caesium and lead provide low-cost, flexible and solution-processable scintillators that are highly sensitive to X-ray irradiation and emit radioluminescence that is colour-tunable across the visible spectrum.
- Published
- 2018
16. Metal Halide Perovskite Nanosheet for X‑ray High-Resolution Scintillation Imaging Screens.
- Author
-
Yuhai Zhang, Ruijia Sun, Xiangyu Ou, Kaifang Fu, Qiushui Chen, Yuchong Ding, Liang-Jin Xu, Lingmei Liu, Yu Han, Malko, Anton V., Xiaogang Liu, Huanghao Yang, Bakr, Osman M., Hong Liu, and Mohammed, Omar F.
- Published
- 2019
- Full Text
- View/download PDF
17. Ankle joint salvage and reconstruction by limited ORIF combined with an Ilizarov external fixator for complex open tibial pilon fractures (AO 43-C3.3) with segmental bone defects
- Author
-
Yu Chen, Yaxing Li, Xiangyu Ouyang, and Hui Zhang
- Subjects
Pilon ,Open fracture ,Bone defect ,Bone grafting ,Ilizarov ,ORIF ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Abstract Background Open pilon fractures combined with sizeable segmental bone defects are rare, difficult to treat, and often result in the loss of ankle joint function. The purpose of this study was to determine clinical outcomes in patients with open pilon fractures and sizeable segmental bone defects treated by limited ORIF combined with an Ilizarov external fixator. Methods We conducted a retrospective analysis of open pilon fractures with sizeable segmental bone defects treated by limited ORIF combined with the Ilizarov external fixator strategy between July 2014 and August 2019. All patients were included for assessments of fracture healing and infection rates. Ankle functional outcomes were assessed in all patients according to the Paley criteria and American Orthopedic Foot and Ankle Society Score (AOFAS) at least 24 months post-injury. Results All patients were followed up for a mean of 41.09 months. The mean bone defect size was 5.64 ± 1.21 cm. The average EFI and BTI were 1.56 ± 0.28 months/cm and 11.12 ± 0.74 days/cm, respectively. According to the Paley evaluation system, the success rate of ankle joint reconstruction was 64% (7/11). The mean score based on the AOFAS functional assessment was 77.73 ± 8.87. Five patients showed posttraumatic arthritis, one of whom required ankle arthrodesis. Three patients developed pin site infections, and one patient developed a deep infection after bone grafting. Conclusion The strategy of limited ORIF combined with an Ilizarov external fixator can restore ankle function in most patients with complex open tibial pilon fractures. Ankle stiffness, pin tract infection, and traumatic arthritis were the most common complications associated with this therapy.
- Published
- 2022
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.