Search

Your search keyword '"Xiao, Menglin"' showing total 43 results
Start Over Author "Xiao, Menglin"
43 results on '"Xiao, Menglin"'

5. Publicly Verifiable Multi-stage Secret Sharing on General Access Structures

Author

SONG Yun, WANG Ningning, XIAO Menglin, SHAO Zhiyi

Subjects
monotone span program (msp), multi-stage secret sharing, bilinear pairing, computational diffie-hellman and decisional bilinear diffie-hellman problems, provably secure, Electronic computers. Computer science, QA75.5-76.95
Abstract

A publicly verifiable secret sharing allows anyone to detect the cheating of dealer or participants only from the public information. In order to expand the application scope of multi-secret sharing, firstly, a publicly verifiable multi-stage secret sharing (PVMSSS) scheme is proposed, and then based on the monotone span program (MSP) and secure multi-party computation, a renewable multi-stage secret sharing scheme that can be publicly verified and used in general access structures is proposed. In the secret distribution stage, the secret share of the participants in the scheme is calculated by each participant, and the dealer does not need to transmit any secret information to the participants. Moreover, each participant only needs to maintain one secret share to realize the reconstruction of multiple secrets. Using bilinear pairing properties, anyone can verify the correctness of the secret shares before and after the update and the validity of the public information, thereby effectively preventing fraud by dealer and participants. In the secret reconstruction phase, the pseudo-share is constructed by using secure multi-party computation to ensure that the real share of each participant will never be exposed, and the versatility of the scheme is realized. In each update of the secret, the dealer only needs to announce the related public information of updated temporary shares to update the participants' secret share. Finally, the correctness and security of the scheme are analyzed. Analysis shows that under the computational Diffie-Hellman and decisional bilinear Diffie-Hellman problems and assumptions, the proposed scheme is provably secure.

Published
2023
Full Text
View/download PDF

6. Practical Provably Secure Encryption Scheme Based on Hashed Bilinear Pairing

Author

Xiao, Menglin, Song, Yun, Wang, Ningning, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Liu, Qi, editor, Liu, Xiaodong, editor, Chen, Bo, editor, Zhang, Yiming, editor, and Peng, Jiansheng, editor

Published
2022
Full Text
View/download PDF

9. Super Stable Silk Nanofibrils Prepared by an Improved Exfoliation Method and Their Related Applications.

Author

Chen, Ling, Liu, Wen, Xiao, Menglin, Sun, Liangyan, Chen, Xiaoxuan, Ni, Lingyue, Yao, Jinrong, Shao, Zhengzhong, Zhao, Bingjiao, and Chen, Xin

Subjects
SILKWORMS, SILK fibroin, HYDROCOLLOID surgical dressings, ANIMAL habitations, SYNTHETIC fibers
Abstract

The high crystallinity and sophisticated hierarchical architecture of native animal silk endow it with comprehensive mechanical properties that are superior to those of most synthetic fibers. However, these features also make the direct exfoliation of silk nanofibrils (SNFs) highly challenging. On the other hand, silk‐based materials prepared by conventional method (i.e., through silk fibroin aqueous solution) are usually weak, so the preparation methods based on SNFs have attracted much attention in recent years. Herein, a facile and environmentally friendly route is developed to directly exfoliate SNFs from natural Bombyx mori silkworm silk via ammonium persulfate oxidation followed by ultrasonication. The obtained SNFs have a high yield (nearly 40%) and are well dispersed in water in a wide pH range, so they can act as a good starting material to prepare subsequent silk‐based materials. The main application of the SNFs demonstrated in this article is a curcumin (Cur)/SNFs hydrogel as wound dressing. In vivo experimental results show that the Cur/SNFs hydrogel significantly enhanced the healing rate of wounds on diabetic mice. Therefore, the preparation method developed in this study provides an efficient way to produce SNFs, which have great potential for a wide range of applications, including as wound dressings for diabetics. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

16. Blockage of EGFR/AKT and mevalonate pathways synergize the antitumor effect of temozolomide by reprogramming energy metabolism in glioblastoma

Author

Cui, Xiaoteng, primary, Zhao, Jixing, additional, Li, Guanzhang, additional, Yang, Chao, additional, Yang, Shixue, additional, Zhan, Qi, additional, Zhou, Junhu, additional, Wang, Yunfei, additional, Xiao, Menglin, additional, Hong, Biao, additional, Yi, Kaikai, additional, Tong, Fei, additional, Tan, Yanli, additional, Wang, Hu, additional, Wang, Qixue, additional, Jiang, Tao, additional, Fang, Chuan, additional, and Kang, Chunsheng, additional

Published
2023
Full Text
View/download PDF

17. EPIC-1042 as a potent PTRF/Cavin1-Caveolin-1 interaction inhibitor to induce PARP1 autophagic degradation and suppress temozolomide efflux for Glioblastoma

Author

Hong, Biao, primary, Yang, Eryan, additional, Su, Dongyuan, additional, Ju, Jiasheng, additional, Cui, Xiaoteng, additional, Wang, Qixue, additional, Tong, Fei, additional, Zhao, Jixing, additional, Yang, Shixue, additional, Cheng, Chunchao, additional, Xin, Lei, additional, Xiao, Menglin, additional, Yi, Kaikai, additional, Zhan, Qi, additional, Ding, Yaqing, additional, Xu, Hanyi, additional, Cui, Longtao, additional, and Kang, Chunsheng, additional

Published
2023
Full Text
View/download PDF

18. Silk-Based 3D Porous Scaffolds for Tissue Engineering

Author

Xiao, Menglin, Yao, Jinrong, Shao, Zhengzhong, and Chen, Xin

Abstract

Silk fibroin, extracted from the silk of the Bombyx morisilkworm, stands out as a biomaterial due to its nontoxic nature, excellent biocompatibility, and adjustable biodegradability. Porous scaffolds, a type of biomaterial, are crucial for creating an optimal microenvironment that supports cell adhesion and proliferation, thereby playing an essential role in tissue remodeling and repair. Therefore, this review focuses on 3D porous silk fibroin-based scaffolds, first summarizing their preparation methods and then detailing their regenerative effects on bone, cartilage, tendon, vascular, neural, skin, hepatic, and tracheal epithelial tissue engineering in recent years.

Published
2024
Full Text
View/download PDF

21. EPIC-0307-mediated selective disruption of PRADX–EZH2 interaction and enhancement of temozolomide sensitivity to glioblastoma via inhibiting DNA repair and MGMT

Author

Xin, Lei, primary, Tan, Yanli, additional, Zhu, Yuanxue, additional, Cui, Xiaoteng, additional, Wang, Qixue, additional, Zhao, Jixing, additional, Tian, Shaohui, additional, Xu, Can, additional, Xiao, Menglin, additional, Hong, Biao, additional, Xu, Jianglong, additional, Yuan, Xiaoye, additional, Wang, Changsheng, additional, Kang, Chunsheng, additional, and Fang, Chuan, additional

Published
2023
Full Text
View/download PDF

25. Additional file 1 of Regenerated silk fibroin based on small aperture scaffolds and marginal sealing hydrogel for osteochondral defect repair

Author

Luo, Yinyue, Xiao, Menglin, Almaqrami, Bushra sufyan, Kang, Hong, Shao, Zhengzhong, Chen, Xin, and Zhang, Ying

Abstract

Additional file 1: Fig. S1. Screening ingredients at different concentrations for n-butanol-inspired small aperture scaffolds in vitro: a) Illustration of cell-scaffold complex preparation; b-j) dsDNA, total GAG, and total collagen content of different HA, COLI, and β-TCP mass ratios of the small aperture scaffolds after co-culturing with chondrocytes or BMSCs for seven days. * represents p < 0.05, ** represents p < 0.01, *** represents p < 0.001 and **** represents p < 0.0001. Fig. S2. The mass loss rate of RSF porous scaffolds in vitro under the action of type XIV collagenase at 37 ℃. a) It shows the RSF/HA group, and b) the RSF/COL group. c) Groups with RSF and β-TCP mass ratios of 1:3, 1:1 and 3:1. Fig. S3. Labelling rate detection of cell fluorescent probes by flow cytometry. a) 99.84% labelling rate of chondrocytes with a red fluorescent probe. b) 84.32% labelling rate of BMSCs with a green fluorescent probe. Fig. S4. mRNA-seq analysis. a) The overall distribution of differentially expressed genes in osteochondral samples from the control and E groups after 4.5 months is shown. Red represents significantly up-regulated differentially expressed genes, blue represents significantly down-regulated differentially expressed genes, and grey dots represent non-significantly differentially expressed genes. b) Compared to the control groups, the E groups have 968 differentially expressed genes, including 340 highly expressed genes and 628 low-expressed genes. Fig. S5. Cell identification. a) Immunofluorescencestaining of collagen type II, aggrecan, and SOX9 of the human chondrocyte line C28/I2. b) IF staining of collagen type II and aggrecan of rabbit chondrocytes from the knee joint.

Published
2023
Full Text
View/download PDF

30. lncRNA PRADX is a Mesenchymal Glioblastoma Biomarker for Cellular Metabolism Targeted Therapy

Author

Xu, Can, primary, Zhao, Jixing, additional, Song, Jia, additional, Xiao, Menglin, additional, Cui, Xiaoteng, additional, Xin, Lei, additional, Xu, Jianglong, additional, Zhang, Yuhao, additional, Yi, Kaikai, additional, Hong, Biao, additional, Tong, Fei, additional, Tian, Shaohui, additional, Tan, Yanli, additional, Kang, Chunsheng, additional, and Fang, Chuan, additional

Published
2022
Full Text
View/download PDF

31. PTRF/Cavin-1 as a Novel RNA-Binding Protein Expedites the NF-κB/PD-L1 Axis by Stabilizing lncRNA NEAT1, Contributing to Tumorigenesis and Immune Evasion in Glioblastoma

Author

Yi, Kaikai, primary, Cui, Xiaoteng, additional, Liu, Xing, additional, Wang, Yunfei, additional, Zhao, Jixing, additional, Yang, Shixue, additional, Xu, Can, additional, Yang, Eryan, additional, Xiao, Menglin, additional, Hong, Biao, additional, Fang, Chuan, additional, Kang, Chunsheng, additional, Tan, Yanli, additional, and Wang, Qixue, additional

Published
2022
Full Text
View/download PDF

32. PTRF/Cavin-1 enhances chemo-resistance and promotes temozolomide efflux through extracellular vesicles in glioblastoma

Author

Yang, Eryan, primary, Wang, Lin, additional, Jin, Weili, additional, Liu, Xing, additional, Wang, Qixue, additional, Wu, Ye, additional, Tan, Yanli, additional, Wang, Yunfei, additional, Cui, Xiaoteng, additional, Zhao, Jixing, additional, Tong, Fei, additional, Hong, Biao, additional, Xiao, Menglin, additional, Liu, Xiaomin, additional, Fang, Chuan, additional, and Kang, Chunsheng, additional

Published
2022
Full Text
View/download PDF

33. RUNX1-CBFβ Complex Modulates lncRNA PRADX Transcription, Activates Stat3 Pathway and Energy Metabolism Via Recruitment of H3K27me3 in Mesenchymal Glioblastoma

Author

Xua, Can, primary, Zhao, Jixing, additional, Song, Jia, additional, Xiao, Menglin, additional, Cui, Xiaoteng, additional, Xin, Lei, additional, Xu, Jianglong, additional, Zhang, Yuhao, additional, Yi, Kaikai, additional, Hong, Biao, additional, Tong, Fei, additional, Tian, Shaohui, additional, Tan, Yanli, additional, Kang, Chunsheng, additional, and Fang, Chuan, additional

Published
2022
Full Text
View/download PDF

42. A novel hydrophobic peptide FGMp11: Insights into antimicrobial properties, hydrophobic sites on Staphylococcus aureusand its application in infecting pasteurized milk

Author

Yang, Tingting, Zheng, Wentao, Wang, Xuefeng, Li, Yufang, Xiao, Menglin, Wei, Guangqiang, Tao, Guanhua, Huang, Aixiang, and Shi, Yanan

Abstract

•A novel antimicrobial peptide FGMp11 derived from fermented goat milk.•FGMp11 is characterized as a highly hydrophobic AMP with a β-turn structure.•The caused irreversible membrane damage and cell wall deformation in S. aureus.•FGMp11 inhibited S. aureusgrowth via hydrogen bonding and hydrophobic interactions with Mur ligase.•Electrostatic binding sites of FGMp11 to the key amino acids GLN, LEU and PRO are mainly -OH, -NH2and -C=O groups.

Published
2024
Full Text
View/download PDF

43. Self-Assembled Regenerated Silk Fibroin Microsphere-Embedded Fe 3 O 4 Magnetic Nanoparticles for Immobilization of Zymolyase.

Author

Xiao M and Lv S

Abstract

Cytoplasm of Saccharomyces cerevisiae yeast cells contains a significant amount of desired intracellular products for both industrial utility and academic research. To recover intracellular compounds, it is necessary to break the yeast cells with high efficiency, which, under certain circumstances, requires the use of the lytic enzyme zymolyase to completely digest the cell walls. A promising strategy for zymolyase immobilization on silk fibroin (SF) was developed. SF/Fe 3 O 4 magnetic microspheres (MMs) were constructed by solvent (ethanol)-induced self-assembly of SF surrounding Fe 3 O 4 magnetic nanoparticles (MNs), which were synthesized by a coprecipitation method. Zymolyase was covalently bonded on the surface of the SF/Fe 3 O 4 MMs by a photochemical cross-linking method to produce robust biocatalysts of zymolyase/SF/Fe 3 O 4 . The chemical, magnetic, and morphological properties of the MM supports and the immobilized zymolyase were investigated. Enzymolysis results demonstrated that the immobilized zymolyase showed good activity and stability for digesting yeast cell walls, and the biocatalyst can be readily recycled through convenient magnetic separation for reuse. At the optimum pH = 7.5, the immobilized zymolyase maintained 84% of the activity of the free zymolyase and retained 41% of its initial activity after four times of reuse. At unfavorable acidic pH = 4, the immobilized zymolyase retained 81% of its initial activity, while the free zymolyase showed no significant activity. Consequently, the SF/Fe 3 O 4 MMs exhibit superior performance in terms of immobilizing enzymes, which have a good prospect in the biological application., Competing Interests: The authors declare no competing financial interest., (Copyright © 2019 American Chemical Society.)

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results