42 results on '"Xiao, S. F."'
Search Results
2. Geometric momentum and angular momentum for charge-monopole system
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Xiao, S. F. and Liu, Q. H.
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Quantum Physics ,High Energy Physics - Theory - Abstract
For a charge-monopole pair, though the definition of the orbital angular momentum is different from the usual one, and the transverse part of the momentum that includes the vector potential as an additive term turns out to be the so-called geometric momentum that is under intensive study recently. For the charge is constrained on the spherical surface with monopole at the origin, the commutation relations between all components of geometric momentum and the orbital angular momentum satisfy the $so(3,1)$ algebra. With construction of the geometrically infinitesimal displacement operator based on the geometric momentum, the $so(3,1)$ algebra implies the Aharonov-Bohm phase shift. The related problems such as charge and flux quantization are also addressed., Comment: 6 pages, no figure. main body sectioned, typos corrected
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- 2018
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3. Surface reconstruction, premelting, and collapse of open-cell nanoporous Cu via thermal annealing
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Wang, L., Zhang, X. M., Deng, L., Tang, J. F., Xiao, S. F., Deng, H. Q., and Hu, W. Y.
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Condensed Matter - Materials Science - Abstract
We systematic investigate the collapse of a set of open-cell nanoporous Cu (np-Cu) with the same porosity and shapes, but different specific surface area, during thermal annealing, via performing large-scale molecular dynamics simulations. Surface premelting is dominated in their collapses, and surface premelting temperatures reduce linearly with the increase of specific surface area. The collapse mechanisms are different for np-Cu with different specific surface area. If the specific surface area less than a critical value ($\sim$ 2.38 nm$^{-1}$), direct surface premelting, giving rise to the transition of ligaments from solid to liquid states, is the cause to facilitate falling-down of np-Cu during thermal annealing. While surface premelting and following recrystallization, accelerating the sloughing of ligaments and annihilation of pores, is the other mechanism, as exceeding the critical specific surface area. The recrystallization occurs at the temperatures below supercooling, where liquid is instable and instantaneous. Thermal-induced surface reconstruction prompts surface premelting via facilitating local "disordering" and "chaotic" at the surface, which are the preferred sites for surface premelting.
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- 2018
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4. Pressure demagnetization: Electromagnetism meets thermodynamics
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Xiao, S. F., primary, Zhao, H., additional, Wei, Y. X., additional, Tan, J. Z., additional, and Liu, Q. H., additional
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- 2024
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5. On relationship between canonical momentum and geometric momentum
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Xiao, S. F. and Liu, Q. H.
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Quantum Physics - Abstract
Decompositing of $N+1$-dimensional gradient operator in terms of Gaussian normal coordinates $(\xi^{0},\xi^{\mu})$, ($\mu=1,2,3,...,N$) and making the canonical momentum $P_{0}$ along the normal direction $\mathbf{n}$ to be hermitian, we obtain $\mathbf{n}P_{0}=-i\hbar\left( \mathbf{n}\partial _{0}-\mathbf{M}_{0}\right) $ with $\mathbf{M}_{0}$ denoting the mean curvature vector on the surface $\xi^{0}=const.$ The remaining part of the momentum operator lies on the surface, which is identical to the geometric one., Comment: 7 pages
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- 2016
6. A self-adjoint decomposition of radial momentum implies that Dirac's introduction of the operator is insightful
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Liu, Q. H. and Xiao, S. F.
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Quantum Physics - Abstract
With acceptance of the Dirac's observation that the \textit{canonical quantization entails using Cartesian coordinates, }we examine the\textit{\ }% operator $\mathbf{e}_{r}P_{r}$ rather than $P_{r}$ itself and demonstrate that there is a decomposition of $\mathbf{e}_{r}P_{r}$ into two self-adjoint but non-commutative parts, in which one is the total momentum and another is the transverse one. This study renders the operator $P_{r}$ indirectly measurable and physically meaningful., Comment: 6 pages, 2 figures
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- 2014
7. A Thermodynamic Pressure Demagnetization
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Xiao, S. F., primary, Zhao, H., additional, Wei, Y. X., additional, Tan, J. Z., additional, and Liu, Q. H., additional
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- 2023
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8. The motifs of crystals and their nano-aggregates
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Lu, X. M., Shi, X. D., Bi, Y. G., Chi, Z. X., Min, T., Zhu, L. L., Xiao, S. F., and Zhong, L. J.
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- 2011
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9. Dynamic characteristic and stability analysis of a beam mounted on a moving rigid body
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Xiao, S. F. and Chen, B.
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- 2005
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10. Ductile-Brittle Transition of Open-Cell Nanoporous Cu in Tension: A Reliance of Specific Surface Area
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Wang, L., primary, Bi, W. B., additional, Deng, L., additional, Xiao, S. F., additional, Li, B., additional, Deng, X. L., additional, Zhang, X. M., additional, Tang, J. F., additional, and Hu, W. Y., additional
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- 2019
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11. Geometric momentum and angular momentum for charge-monopole system
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Xiao, S. F., primary and Liu, Q. H., additional
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- 2018
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12. Surface premelting/recrystallization governing the collapse of open-cell nanoporous Cu via thermal annealing
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Wang, L., primary, Zhang, X. M., additional, Deng, L., additional, Tang, J. F., additional, Xiao, S. F., additional, Deng, H. Q., additional, and Hu, W. Y., additional
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- 2018
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13. Shock wave propagation, plasticity, and void collapse in open-cell nanoporous Ta
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Tang, J. F., primary, Xiao, J. C., additional, Deng, L., additional, Li, W., additional, Zhang, X. M., additional, Wang, L., additional, Xiao, S. F., additional, Deng, H. Q., additional, and Hu, W. Y., additional
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- 2018
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14. A self-adjoint decomposition of the radial momentum operator
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Liu, Q. H., primary and Xiao, S. F., additional
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- 2015
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15. The role of the arc erosion in sever wear of carbon strip/copper contact wire in pantograph-catenry system
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Ding, T., primary, Chen, G. X., additional, Xiao, S. F., additional, Xie, L., additional, and Zeng, Q. D., additional
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- 2011
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16. The motifs of crystals and their nano-aggregates
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Lu, X. M., primary, Shi, X. D., additional, Bi, Y. G., additional, Chi, Z. X., additional, Min, T., additional, Zhu, L. L., additional, Xiao, S. F., additional, and Zhong, L. J., additional
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- 2010
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17. NONLINEAR DYNAMIC MODELING, INSTABILITY AND POST-BUCKLING ANALYSIS OF A ROTATING BEAM WITH A FLEXIBLE SUPPORT
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XIAO, S. F., primary and YANG, M., additional
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- 2006
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18. Inhibitory Effect of Half-face Masks on Inhalation of Particles of Carbon Powder and Japanese Cedar Pollen
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Xiao, S. F., primary, Okuda, M., additional, and Tanimoto, H., additional
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- 1991
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19. Monolithic lithium-based aerogels via dispersed inorganic sol-gel method
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Xiao, S. -F, Zhou, B., Wan, H. -J, Du, A., Xu, X., Xiaoyun Yang, Shen, J., Wu, G. -M, and Zhang, Z. -H
20. Rapid preparation and characterization of the nickel-containing silica aerogels
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Xiao, S. -F, Zhou, B., Yang, X. -Y, Ai Du, Zhang, Z. -H, Wu, G. -M, and Shen, J.
21. [Different methods in predicting mortality of pediatric intensive care units sepsis in Southwest China].
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Liu R, Yu ZC, Xiao CX, Xiao SF, He J, Shi Y, Hua YY, Zhou JM, Zhang GY, Wang T, Jiang JY, Xiong DX, Chen Y, Xu HB, Yun H, Sun H, Pan TT, Wang R, Zhu SM, Huang D, Liu YJ, Hu YH, Ren XR, Shi MF, Song SZ, Luo JM, Liu J, Zhang J, and Xu F
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- Humans, Child, Male, Female, Prospective Studies, Retrospective Studies, Systemic Inflammatory Response Syndrome diagnosis, Intensive Care Units, Pediatric, Prognosis, China epidemiology, Critical Illness, ROC Curve, Intensive Care Units, Sepsis diagnosis
- Abstract
Objective: To investigate the value of systemic inflammatory response syndrome (SIRS), pediatric sequential organ failure assessment (pSOFA) and pediatric critical illness score (PCIS) in predicting mortality of pediatric sepsis in pediatric intensive care units (PICU) from Southwest China. Methods: This was a prospective multicenter observational study. A total of 447 children with sepsis admitted to 12 PICU in Southwest China from April 2022 to March 2023 were enrolled. Based on the prognosis, the patients were divided into survival group and non-survival group. The physiological parameters of SIRS, pSOFA and PCIS were recorded and scored within 24 h after PICU admission. The general clinical data and some laboratory results were recorded. The area under the curve (AUC) of the receiver operating characteristic curve was used to compare the predictive value of SIRS, pSOFA and PCIS in mortality of pediatric sepsis. Results: Amongst 447 children with sepsis, 260 patients were male and 187 patients were female, aged 2.5 (0.8, 7.0) years, 405 patients were in the survival group and 42 patients were in the non-survival group. 418 patients (93.5%) met the criteria of SIRS, and 440 patients (98.4%) met the criteria of pSOFA≥2. There was no significant difference in the number of items meeting the SIRS criteria between the survival group and the non-survival group (3(2, 4) vs. 3(3, 4) points, Z= 1.30, P= 0.192). The pSOFA score of the non-survival group was significantly higher than that of the survival group (9(6, 12) vs . 4(3, 7) points, Z= 6.56, P< 0.001), and the PCIS score was significantly lower than that of the survival group (72(68, 81) vs . 82(76, 88) points, Z= 5.90, P< 0.001). The predictive value of pSOFA (AUC=0.82) and PCIS (AUC=0.78) for sepsis mortality was significantly higher than that of SIRS (AUC=0.56) ( Z= 6.59, 4.23, both P< 0.001). There was no significant difference between pSOFA and PCIS ( Z= 1.35, P= 0.176). Platelet count, procalcitonin, lactic acid, albumin, creatinine, total bilirubin, activated partial thromboplastin time, prothrombin time and international normalized ratio were all able to predict mortality of sepsis to a certain degree (AUC=0.64, 0.68, 0.80, 0.64, 0.68, 0.60, 0.77, 0.75, 0.76, all P< 0.05). Conclusion: Compared with SIRS, both pSOFA and PCIS had better predictive value in the mortality of pediatric sepsis in PICU.
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- 2024
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22. [Analysis of risk factors of mortality in infants and toddlers with moderate to severe pediatric acute respiratory distress syndrome].
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Fang BL, Xu F, Lu GP, Ren XX, Zhang YC, Jin YP, Wang Y, Liu CF, Cheng YB, Yang QZ, Xiao SF, Yang YY, Huo XM, Lei ZX, Dang HX, Liu S, Wu ZY, Li KC, Qian SY, and Zeng JS
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- Female, Male, Humans, Child, Preschool, Infant, Child, Critical Illness, Retrospective Studies, Risk Factors, Pulmonary Surfactants therapeutic use, Respiratory Distress Syndrome therapy
- Abstract
Objective: To identify the risk factors in mortality of pediatric acute respiratory distress syndrome (PARDS) in pediatric intensive care unit (PICU). Methods: Second analysis of the data collected in the "efficacy of pulmonary surfactant (PS) in the treatment of children with moderate to severe PARDS" program. Retrospective case summary of the risk factors of mortality of children with moderate to severe PARDS who admitted in 14 participating tertiary PICU between December 2016 to December 2021. Differences in general condition, underlying diseases, oxygenation index, and mechanical ventilation were compared after the group was divided by survival at PICU discharge. When comparing between groups, the Mann-Whitney U test was used for measurement data, and the chi-square test was used for counting data. Receiver Operating Characteristic (ROC) curves were used to assess the accuracy of oxygen index (OI) in predicting mortality. Multivariate Logistic regression analysis was used to identify the risk factors for mortality. Results: Among 101 children with moderate to severe PARDS, 63 (62.4%) were males, 38 (37.6%) were females, aged (12±8) months. There were 23 cases in the non-survival group and 78 cases in the survival group. The combined rates of underlying diseases (52.2% (12/23) vs. 29.5% (23/78), χ
2 =4.04 , P =0.045) and immune deficiency (30.4% (7/23) vs . 11.5% (9/78), χ2 =4.76, P =0.029) in non-survival patients were significantly higher than those in survival patients, while the use of pulmonary surfactant (PS) was significantly lower (8.7% (2/23) vs. 41.0% (32/78), χ2 =8.31, P =0.004). No significant differences existed in age, sex, pediatric critical illness score, etiology of PARDS, mechanical ventilation mode and fluid balance within 72 h (all P >0.05). OI on the first day (11.9(8.3, 17.1) vs. 15.5(11.7, 23.0)), the second day (10.1(7.6, 16.6) vs .14.8(9.3, 26.2)) and the third day (9.2(6.6, 16.6) vs. 16.7(11.2, 31.4)) after PARDS identified were all higher in non-survival group compared to survival group ( Z =-2.70, -2.52, -3.79 respectively, all P <0.05), and the improvement of OI in non-survival group was worse (0.03(-0.32, 0.31) vs . 0.32(-0.02, 0.56), Z =-2.49, P =0.013). ROC curve analysis showed that the OI on the thind day was more appropriate in predicting in-hospital mortality (area under the curve= 0.76, standard error 0.05,95% CI 0.65-0.87, P <0.001). When OI was set at 11.1, the sensitivity was 78.3% (95% CI 58.1%-90.3%), and the specificity was 60.3% (95% CI 49.2%-70.4%). Multivariate Logistic regression analysis showed that after adjusting for age, sex, pediatric critical illness score and fluid load within 72 h, no use of PS ( OR =11.26, 95% CI 2.19-57.95, P =0.004), OI value on the third day ( OR =7.93, 95% CI 1.51-41.69, P =0.014), and companied with immunodeficiency ( OR =4.72, 95% CI 1.17-19.02 , P =0.029) were independent risk factors for mortality in children with PARDS. Conclusions: The mortality of patients with moderate to severe PARDS is high, and immunodeficiency, no use of PS and OI on the third day after PARDS identified are the independent risk factors related to mortality. The OI on the third day after PARDS identified could be used to predict mortality.- Published
- 2023
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23. [Comparison between transoral radiofrequency coblation surgery and open partial laryngectomy for the treatment of supraglottic laryngeal carcinoma].
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Guan SW, Wen F, Shen H, Zhao EM, Qin Y, and Xiao SF
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- Male, Female, Humans, Middle Aged, Aged, Laryngectomy methods, Blood Loss, Surgical, Retrospective Studies, Neoplasm Staging, Treatment Outcome, Glottis surgery, Glottis pathology, Larynx pathology, Laryngeal Neoplasms pathology, Carcinoma pathology
- Abstract
Objective: To explore the feasibility and efficacy of radiofrequency coblation assisted transoral surgery for the treatment of supraglottic laryngeal carcinoma by comparing with concurrent patients treated with conventional transcervical approach. To clarify the advantages of different surgical methods and to summarize the experience of supraglottic carcinoma radiofrequency ablation. Methods: Forty-six patients with supraglottic laryngeal carcinoma treated in department of otorhinolaryngology head and neck surgery, Peking University First Hospital from March 2014 to January 2021 were analyzed retrospectively. Among them(43 males, 3 females, aged from 45 to 79 years old), 23 patients were treated with radiofrequency coblation and 23 patients with partial laryngectomy with conventional transcervical approach. The operation time, intra-operative blood loss volume, recovery time, inpatient total medical cost and follow-up information of the two groups were analyzed. SPSS 26.0 software was used for statistical analysis. Results: There were no significant differences in age, gender, TNM staging,tumor staging and postoperative radiotherapy between the two groups (all P >0.05).The operation time, intra-operative blood loss volume, recovery time, inpatient total medical cost of the RFC-TOS group were110.0(60.0,150.0)min,5.0(5.0,30.0)ml,3.0(2.0,5.0)days,6.0(4.0,14.0)days and 26 100.7(16 145.5,47 044.4)yuan. The data of conventional transcervical approach group were 205.0(156.5,272.3)min, 150.0(50,200) ml, 18.0(16.3,22.8)days and 56520.1(440 992.5,67 109.9)yuan, ( Z =-4.03, -4.94, -4.97, -4.98 and -4.13;all P< 0.001).The 5-year local control rate, disease-specific survival rate and overall survival rate of the two groups were 86.96%,95.65%,91.30% and 86.96%,91.30%,73.90% renspectively, which had no significant difference between the two groups(all P >0.05). Conclusions: Compared with conventional transcervical surgeries, RFC-TOS could be a reliable new surgical option for organ-function preservation strategy in the treatment of supraglottic laryngeal carcinoma.The RFC is a suitable new technique and deserving more multi-center clinical trials for its clinical promotion.
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- 2022
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24. [Two cases of subglottic inflammatory myofibroblastic tumor].
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Guan SW, Wen F, Su WW, Qin Y, and Xiao SF
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- Humans, Granuloma, Plasma Cell pathology, Granuloma, Plasma Cell surgery, Neoplasms
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- 2022
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25. [Correlation study between changes in intestinal microflora structure and immune indexes in newly treated patients with pulmonary tuberculosis].
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Xie JH, Yu R, Shi GM, Ma XH, Xiao SF, Yi YH, Zhou T, and Xiang YG
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- Case-Control Studies, Correlation of Data, Humans, Monocytes, Gastrointestinal Microbiome, Tuberculosis, Pulmonary
- Abstract
To explore the correlation between the changes of the intestinal flora of newly treated pulmonary tuberculosis patients and the immune indicators of the body, and to provide a reference for the prevention and treatment of pulmonary tuberculosis. A single-center and case-control study was adopted. From October 2020 to April 2021, 43 patients with newly diagnosed tuberculosis in the Department of Tuberculosis, Affiliated Changsha Central Hospital,University of South China were selected as the control group. 43 cases of newly treated pulmonary tuberculosis (PTB), 43 healthy control (HC) during the same period, collected fresh feces and whole blood of subjects, and used Illumina Hiseq high-throughput sequencing technology to analyze 16S of all microorganisms in feces The V4 region of rRNA was amplified and sequenced, and the structure of the intestinal flora was analyzed by QIIME software. Use flow cytometry to determine the subject's immune indicators (CD3
+ , CD4+ , CD8+ , CD4+ CD25+ CD127- Treg, CD14+ CD16+ , CD14+ CD16- ), and analyze the changes in intestinal flora and immune function in newly treated pulmonary tuberculosis patients Inherent connection. The χ² test, t test, and Wilcox rank sum test were used to analyze the differences in age, gender, α diversity, and relative abundance of the two groups of people. Compared with the HC group, the alpha diversity of the intestinal flora in the PTB group decreased (shannon index: t =3.906, P =0.000 2; simpson index: Z =553, P =0.004 7; chao1 index: t =5.395, P =0.000 0). β diversity analysis showed that there were significant differences in the structure of the intestinal flora between the two groups ( P =0.000). Species difference analysis showed that at the phylum level, the relative abundance of Firmicutes in the PTB group was significantly lower than that in the HC group ( Z =486.0, P =0.000 5). At the genus level, there are 15 different bacterial genera between the two groups. In the PTB group, bifidobacterium, enterococcus, lactobacillus, anaerostipes, the relative abundance of the above 5 genera of veillonella is higher than that of the HC group ( P <0.05); Butyricimonas, clostridium, and broutella (blautia), coprococcus, dorea, lachnospira, roseburia, faecalibacterium, ruminococcus, the relative abundance of 10 bacterial genera including dialister was lower than that of the HC group ( P <0.05). Comparison of immune indexes between groups showed that CD14+ CD16+ monocytes (%) in the PTB group were higher than those in the HC group ( t =2.456, P =0.001 6<0.05), while CD14+ CD16- monocytes (%) were lower than HC ( t =-4.368, P =0.000<0.05), while the differences in CD3+ , CD4+ , CD8+ , CD4+ /CD8+ and Treg (CD4+ CD25+ CD127- ) were not statistically significant ( P >0.05). Spearman correlation analysis showed that Firmicutes in the PTB group was negatively correlated with CD4+ /CD8+ , CD14+ CD16+ ( r =-0.218, P =0.048; r =-0.245, P =0.025), and positively correlated with CD14+ CD16- Correlation ( r =0.250, P =0.022); At the genus level, Faecalis is positively correlated with CD4+ /CD8+ and CD4+ ( r =0.250, P =0.023; r =0.258, P =0.019); Rosella and CD3+ , CD8+ and CD14+ CD16- are positively correlated ( r =0.27, P =0.024; r =0.219, P =0.046; r =0.027, P =0.039), and negatively correlated with CD14+ CD16+ ( r =-0.280, P = 0.01). Changes in the structure of the intestinal flora of newly treated pulmonary tuberculosis patients may be one of the influencing factors of the immune function of the body. Targeted optimization of the structure of the intestinal flora and improvement of the body's immunity may be used as an effective auxiliary treatment for pulmonary tuberculosis.- Published
- 2021
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26. [Interpretation on the expert consensus of diagnosis and treatment of vocal fold paralysis].
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Chen SC, Zheng HL, and Xiao SF
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- Consensus, Humans, Laryngoscopy, Vocal Cord Paralysis surgery, Vocal Cord Paralysis therapy, Vocal Cords
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- 2021
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27. [Predictive values of the combination of Friedman stage and sleep oximetry done early after surgery in predicting the treatment outcomes of uvulopalatopharyngoplasty].
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Dong BW, Zhang JB, and Xiao SF
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- Adult, Humans, Palate, Polysomnography, Treatment Outcome, Oximetry, Pharynx
- Abstract
Objective: To explore the predictive values of the combination of preoperative data, including medical history and physical examination, and results of sleep oximetry performed early after the surgery (one week) in predicting the treatment outcomes of uvulopalatopharyngoplasty (UPPP) in adult patients with obstructive sleep apnea hypopnea syndrome (OSAHS)., Methods: All the patients who were diagnosed with OSAHS, underwent UPPP treatment and had complete follow-up data in our institution between Jan 2013 and May 2016 were enrolled in our study. The pre-operative data of these patients, including age, physical examination, and polysomnography (PSG) data, were all exactly collected for analysis. All these patients had received the evaluation of subjective efficacy scale and the sleep oximetry test in early post-operative days (within one week). The long-term efficacy evaluations including PSG and subjective efficacy scale were all finished at least three months after the surgery., Results: In the research 61 patients were finally studied, including 25 responders (41.0%) and 36 non-responders (59.0%). Regression analysis revealed that the pre-operative Friedman stage and early post-operative oxygen desaturation index of ≥4% (ODI4) were found to be independently predictive parameters for the UPPP treatment outcomes (P<0.05). The ROC curve analysis was used to estimate the predictive values of ODI4 to the treatment outcomes, and it was calculated with an area under the curve of 0.822. Using the ODI4 of 15 as the cutoff value, the sensitivity and specificity of that calculated were up to 0.778 and 0.760 respectively. The response rate among the patients with an early post-operative ODI4 of <15 was 70.4%, which was significantly higher than that of the patients with an early post-operative ODI4 of ≥15, whose response rate was 17.6% (P<0.05). The similar results could also be obtained in the patients with pre-operative Friedman stage II (87.5% vs.25.0%) and Friedman stage III (33.3% vs. 6.7%)., Conclusion: The combination of early post UPPP operation oximetry parameters, especially ODI4, and pre-operative Friedman stage could be used in better evaluating the potential surgical outcomes of UPPP.
- Published
- 2020
28. [Several issues analysis on the treatment of Alzheimer's disease with rivastigmine transdermal patch].
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Jia JP, Chen SD, Guo QH, Ji Y, Luo BY, Ning YP, Peng DT, Wang YP, Wei WW, Xiao J, Xiao SF, Xiao WZ, Yuan Q, Zhang JJ, Zhang W, Xu RL, and Yang YH
- Subjects
- Humans, Transdermal Patch, Treatment Outcome, Alzheimer Disease drug therapy, Rivastigmine therapeutic use
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- 2020
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29. [Perioperative airway management of OSA patients].
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Xiao SF, Du XW, and Zhang JB
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- Humans, Sleep Apnea, Obstructive, Airway Management, Perioperative Care
- Abstract
Competing Interests: The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose.
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- 2019
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30. [Analysis and surgical treatment of 72 cases of parapharyngeal space tumors].
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Wen F, Shen H, Gao WH, wANG QG, Qin Y, and Xiao SF
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Objective: To summarize and analyze the clinical features, diagnosis methods, surgical approaches and treatment outcomes of patients with parapharygeal space tumors. Method: A retrospective review of 72 cases with parapharygeal space tumors treated from March 1994 to June 2017 was performed. The data on presentation, surgical approach, histological diagnosis and postoperative complications were reviewed. Result: The postoperative pathological diagnosis included 62 benign tumors and 10 malignant tumors. The most frequent symptom was a cervical mass or an intraoral swelling. All patients underwent preoperative enhanced CT scan or MRI,which would be helpful to evaluate the tumor sizes,locations and possible sources,and to make operation scheme. The postoperative pathology included 24 salivary gland lesions and 30 neurogenic lesions. The postoperative complications happened in 13 patients. The surgical approaches included trans-cervical approach in 55 cases, cervical-parotid approach in 9 cases,trans-oral approach in 6 cases , and trans skull base approach in 2 case. Conclusion: A parapharygeal space tumor is an uncommon tumor and requires careful preoperative assessment. Surgery is the first choice for parapharygeal space tumors. These patients should be counseled appropriately about the potential for permanent cranial nerve deficits., Competing Interests: The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose., (Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.)
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- 2018
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31. [Explanation of the experts consensus on diagnosis and treatment of laryngeal leukoplakia].
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Chen DH, Zheng HL, Xiao SF, and Xu W
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- 2018
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32. [The clinical assessment of regional resection in the benign tumor of parotid gland].
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Gu HB, Zhao EM, Li TC, Shen H, Cong TC, Qin Y, Liu YH, and Xiao SF
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- Facial Paralysis, Humans, Neoplasm Recurrence, Local, Parotid Gland surgery, Parotid Neoplasms diagnosis, Parotid Neoplasms surgery, Postoperative Complications, Retrospective Studies, Parotid Gland pathology, Parotid Neoplasms pathology
- Abstract
Objective: To evaluate the clinical assessment of regional resection and superficial lobe total resection in the treatment of benign tumors of the parotid gland. Method: One hundred and nighty-five patients operated in the First Hospital of Peking University from January 1998 to March 2017 with benign tumor of the parotid gland were retrospectively analyzed. There were 189 patients with single side tumor and 6 patients with bilateral sides, 157 cases underwent regional resection and the other 44 cases underwent superficial lobe total resection. All the results and complications were recorded and analyzed between the two groups. Result: There were total 195 patients with 201 cases. All the complications were as follows, 4 cases with recurrence, 44 cases with temporal facial paralysis, 13 cases with permanent facial paralysis, 80 cases with earlobe numbness, 49 cases with facial numbness, 44 cases with skin retraction, 26 cases with operated region effusion, 2 cases with sialosyrinx, 55 cases with Frey syndrome. There were no significant differences between the two groups in the incidences of recurrence, temporal facial paralysis, permanent facial paralysis, earlobe numbness, facial numbness, skin retraction. The incidence of Frey syndrome in the superficial lobe total resection group was significantly higher than the regional resection group(45.5%, 22.3%, P <0.05). The incidence of operated region effusion or sialosyrinx in the regional resection group was significantly higher than the superficial lobe total resection group (16.6%, 4.5%, P <0.05),further analysis showed that the operation method and the location of the tumor were the independent risk factors. Conclusion: Regional resection in the parotid gland tumor was less invasive, the incidences in the most complications were in consistent with superficial lobe total resection, and it was helpful in preventing the occurrence of Frey syndrome. Although regional resection conserved more parotid gland tissue so that the more conserved gland function and it also did not increase the incidence of sialosyrinx, the operated region effusion was significantly increased. If the operated region effusion was not discovered and handled, there would be a risk of sialosyrinx., Competing Interests: The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose., (Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.)
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- 2018
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33. [Clinical observation of coblation assisted transoral microsurgery for the treatment of oral and oropharygneal malignancy].
- Author
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Xiao SF, Zhao X, Zhang JB, Shen H, and Zhao EM
- Subjects
- Carcinoma, Squamous Cell, Humans, Neck Dissection, Neoplasm Staging, Retrospective Studies, Microsurgery, Mouth Neoplasms surgery, Oropharyngeal Neoplasms surgery, Tongue Neoplasms surgery
- Abstract
Objective: To evaluate the feasibility and effectiveness of coblation assisted transoral surgery for the treatment of oral and oropharyngeal malignancy. Method: 19 patients who suffered from oral or oropharyngeal malignant tumors underwent coblation assisted transoral surgery from August 2008 to August 2017 were studied. According to the tumor sites and pathological results, there were four oral squamous cell carcinoma (SCC) (two tongue carcinoma and two mouth floor carcinoma), eleven oropharygneal SCC (five tonsillar carcinoma, four soft palate carcinoma, one tongue base cartinama and one multiple carcinoma invading both soft palatine and hypopharynx), and four lymphatic and hematopoietic malignancies (three tonsillar tumors and one tumor invading both tonsil and tongue base). According to AJCC guideline, the stages of four oral SCC were T₁N₀M₀, T₁N₂M₀, T₂N₁M₀, and T₂N₂M₀ respectively; while the stages of eleven orophygneal SCC were T₁N₀M₀ for 5 patients, T₂N₀M₀ for 4 patients, T₂N₁M₀ for one patient, and T₂N₂M₀ for one patient respectively. Result: Among the 19 patients studied, concurrent neck dissections and tracheotomies were performed in six and four patients respectively. For all the transoral procedures, the blood loss could be controlled within 20 ml, while the operative time were controlled within two hours. 13 patients started oral feeding the day they were operated on. All of the four patients who underwent the tracheotomy could be decannulated successfully after surgery. Four patients diagnosed as lymphatic and hematopoietic malignancies turned to hematology department for further treatments. For the remaining 15 SCC patients, 14 were followed up successfully with one loss to follow-up: the follow up time ranged from 6 to 108 months, during these times, one patient with multiple carcinomas invading the soft palate and hypopharynx had developed new carcinomas located in contralateral hypopharynx and esophagus and had the metastasis in cervical lymph nodes 5 months after surgery, another patient with soft palate carcinoma had the metastasis in cervical lymph nodes 18 months after surgery. Two patients died because of intracranial hemorrhage and cardiovascular event 5 and 12 months after surgery respectively. The three years' tumor free survival and overall survival rates calculated by Kaplan-Meier method were 75.0% and 77.9% respectively. All patients had no severe dysfunctions for swallow, speech and breathing related to the surgery. Conclusion: Radiofrenquency coblation assisted transoral surgery for oral and oropharygneal carcinoma has definite therapeutic effect. Most cases can avoid open surgery and tracheotomy.The advantages are blood control, simplifing surgery,shortening operational time,faster recovery, lower incidence of complications and better preservation of organ function., Competing Interests: The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose., (Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.)
- Published
- 2017
- Full Text
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34. [Transoral radiofrequency coblation surgery for the treatment of hypopharyngeal carcinoma].
- Author
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Xiao SF, Li WY, Zhang JB, Wang J, Jia JX, Yang DH, Zhao X, Huo H, and Shen H
- Subjects
- Carcinoma mortality, Carcinoma pathology, Carcinoma radiotherapy, Combined Modality Therapy methods, Feasibility Studies, Female, Humans, Hypopharyngeal Neoplasms mortality, Hypopharyngeal Neoplasms pathology, Hypopharyngeal Neoplasms radiotherapy, Kaplan-Meier Estimate, Laryngeal Neoplasms surgery, Lost to Follow-Up, Male, Neck Dissection, Pyriform Sinus pathology, Survival Rate, Tracheotomy, Carcinoma surgery, Catheter Ablation methods, Hypopharyngeal Neoplasms surgery, Pyriform Sinus surgery
- Abstract
Objective: To explore the feasibility and effectiveness of transoral surgery (TOS) for the treatment of hypopharyngeal carcinoma by means of the radiofrequency coblation(RFC). Methods: Twenty-two patients with hypopharyngeal carcinoma who were treated with TOS using RFC during the years of 2010-2016 were enrolled. Among these patients, 15 suffered from pyriform sinus carcinoma, 4 suffered from postcricoid carcinoma, and 3 suffered from posterior hypopharyngeal wall carcinoma. According to the AJCC 2002 guideline, the tumor stages were T1N0M0 for 3 patients, T2N0M0 for 9 patients, T1N1M0 for 1 patient, T1N2M0 for 1 patient, T2N1M0 for 4 patients, and T2N2M0 for 4 patients respectively. All patients with N+ underwent concurrent neck dissection; 2 patients underwent concurrent prophylactic tracheotomy; 17 underwent post-operative radiotherapy for 50-66 Gy. The follow-up time was 6-72 months with a median 35 months.Two patients were lost to follow-up. Results: All patients except 2 underwent the TOS successfully, while the two patients were treated with open approach surgery due to unsure safe margin. Most patients returned to oral feeding within one week. Among the 18 patients with complete follow up data, 3 had the local recurrence of the tumor (16.7%) and one died due to local recurrence, multiple primary esophageal carcinoma, and distant metastasis 4 years after surgery (5.6%). According to the Kaplan-Meier method, the 5-years local control rate and survival rate were 57.8% and 67.5% respectively. All patients had no disorders in speech, swallowing and respiration during the follow up. Conclusions: The RFC can be applied in TOS for the treatments of hypopharyngeal carcinoma with high cutting efficiency and better control of intraoperative hemorrhage, which is useful in lowering the operation difficulty. The oncologic results are comparable to the open surgery with satisfactory postoperative organ function preservation.
- Published
- 2017
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35. [Transoral microsurgery for the treatment of pharyngeal and laryngeal malignancy].
- Author
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Xiao SF
- Subjects
- Female, Humans, Male, Pharyngeal Neoplasms surgery, Carcinoma, Squamous Cell surgery, Laryngeal Neoplasms surgery, Microsurgery methods
- Published
- 2017
- Full Text
- View/download PDF
36. [Treatment progress of obstructive sleep apnea hypopnea syndrome].
- Author
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Xiao SF, Jia JX, and Zhang JB
- Abstract
Competing Interests: The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose.
- Published
- 2016
- Full Text
- View/download PDF
37. [The clinical application of coblation in laryngopharyngeal,head and neck surgery].
- Author
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Xiao SF
- Abstract
Competing Interests: The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose.
- Published
- 2016
- Full Text
- View/download PDF
38. [Clinical analysis of chronic invasive fungal rhinosinusitis].
- Author
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Li TC, Zeng ZG, Xiao SF, Qin Y, Wang H, and Wang QG
- Subjects
- Anti-Bacterial Agents adverse effects, Antifungal Agents therapeutic use, Aspergillosis microbiology, Aspergillosis therapy, Chronic Disease, Ethmoid Sinusitis microbiology, Ethmoid Sinusitis therapy, Facial Injuries complications, Female, Humans, Immunocompetence, Invasive Fungal Infections therapy, Magnetic Resonance Imaging, Male, Maxillary Sinusitis microbiology, Maxillary Sinusitis therapy, Postoperative Period, Retrospective Studies, Rhinitis microbiology, Rhinitis therapy, Tomography, X-Ray Computed, Aspergillosis diagnosis, Ethmoid Sinusitis diagnosis, Invasive Fungal Infections diagnosis, Maxillary Sinusitis diagnosis, Rhinitis diagnosis
- Abstract
Objective: To investigate the clinical features and treatment of chronic invasive fungal rhinosinusitis(CIFRS)., Methods: From June 2006 to August 2011, seven patients were pathologically diagnosed as CIFRS in otorhinolaryngology department of Peking university first hospital and included in this study. The clinical records were reviewed. The clinical features, clinical course, symptoms, clinical signs, CT/MRI scan of the sinuses, surgical approach, postoperative pathology and medications were analyzed retrospectively. These 7 patients received both surgical and systemic anti-fungal treatment. Among them, 2 cases with characteristically clinical features were addressed into further analyses to explore the clinical feature and treatment of CIFRS., Results: Among the 7 patients, 5 were female and 2 were male. The course of diseases were from 2 months to 8 years. All patients had no systemic immune diseases and history of diabetes mellitus, while 1 case had a history of facial trauma, and another 1 case had received antibiotics for long-stay in bed after a car accident. The onset lesions of 6 cases were in unilateral maxillary sinus and 1 in unilateral ethmoid sinus. Aspergillus fungi were detected in 6 cases and mold fungi were detected in 1 case by pathology or fungal culture. After follow-up for 1-5 years, 6 patients were cured, and 1 was died., Conclusions: CIFRS are often diagnosed in patients with normal immune function. Lesions alwasys occur in single sinus, and maxillary sinus is the most commonly involved.Aspergillus is the most common pathogens. Early clinical manifestation and sinus CT images are lack of specificity. Surgery associated with adequate antifungal treatment might be the best treatment strategy.
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- 2016
- Full Text
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39. [A case of bisphosphonate-related osteonecrosis of the jaws involved in nasal cavity and sinus].
- Author
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Zhao TT, Zhong Z, Zeng ZG, An JG, and Xiao SF
- Published
- 2016
- Full Text
- View/download PDF
40. [Review of bisphosphonate related osteonecrosis of the jaws].
- Author
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Zhao TT, Zhong Z, and Xiao SF
- Subjects
- Bisphosphonate-Associated Osteonecrosis of the Jaw complications, Diphosphonates, Humans, Jaw pathology, Maxillary Sinusitis etiology, Bisphosphonate-Associated Osteonecrosis of the Jaw diagnosis, Bone Density Conservation Agents adverse effects
- Abstract
The bisphosphonates (BPs) has been widely used as anti-resorptive agents owing to their anti-osteoclatic action. However, patients treated with BPs for a long time may subsequently develop bisphosphonate-related osteonecrosis of the jaws (BRONJ). Now, the exact pathogenesis of the BRONJ is poorly understood. There were also no standard diagnosis and treatment methods for this complication. The maxilla necrosis related to BRONJ can cause maxillary sinusitis, fistula, and sinus tract, which arose more attention from the otolaryngologists. In this article, the pathogenesis, symptoms, and treatments of BRONJ are systemically reviewed. The aim is to deepen the recognition of this complication to otolaryngologists, and to avoid missed diagnosis and misdiagnosis. It is hoped that an early diagnosis and suitable treatments could be provided for a good prognosis in such patients., Competing Interests: The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose., (Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.)
- Published
- 2016
- Full Text
- View/download PDF
41. A preliminary analysis of incidence of dementia in Shanghai, China.
- Author
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Zhang M, Katzman R, Yu E, Liu W, Xiao SF, and Yan H
- Subjects
- Aged, Aged, 80 and over, China epidemiology, Cohort Studies, Cross-Cultural Comparison, Cross-Sectional Studies, Female, Follow-Up Studies, Geriatric Assessment statistics & numerical data, Humans, Incidence, Male, Dementia epidemiology, Urban Population statistics & numerical data
- Abstract
The incidence of dementia based on DSM-III criteria and the impact of age and education on the development of dementia using the data of a longitudinal community population survey is discussed. Study subjects were randomly sampled from the community and were assessed by a two-stage procedure twice during a 5-year period. The screening instrument was the Mini-Mental State Examination and the second stage measures include a medical history and physical examination, a neurological examination and an intensive neuropsychiatric interview and testings (i.e. Blessed Dementia Scale, Activity of Daily Living, Fuld Object Memory Test and Block Design Test. All identified cases from the second stage interview were further verified by computed tomographic scan and laboratory tests. A total of 1970 subjects of non-dementia aged 65 or older in 1987 were re-surveyed after 5 years, of whom 114 new cases of dementia were identified. The incidence of dementia in total was 1.15% annually, 0.98% for males and 1.27% for females. The incidence for Alzheimer's disease, vascular dementia and dementia by other causes was 0.74, 0.33 and 0.08%, respectively. The highest rate (2.02%) was found in illiterate individuals. The incidence of dementia in the Shanghai cohort is similar to that from other countries. Age and education are closely related to the occurrence of dementia. While age increases by each 5 years for those aged 65 and over the likelihood of developing dementia increases nearly one-fold (74%). Education shows great protective effect on the development of dementia. The non-educated has a higher risk of suffering from dementia than does the educated.
- Published
- 1998
- Full Text
- View/download PDF
42. Specific IgA and IgG antibodies to house dust mite Dermatophagoides farinae in nasal secretions.
- Author
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Xiao SF, Okuda M, Ohnishi M, and Okubo K
- Subjects
- Adolescent, Adult, Aged, Animals, Child, Humans, Immunoglobulin A, Secretory analysis, Middle Aged, Saliva immunology, Immunoglobulin A analysis, Immunoglobulin G analysis, Mites immunology, Nasal Mucosa immunology, Nasal Mucosa metabolism, Rhinitis, Allergic, Perennial immunology
- Abstract
As far as we know, IgA and IgG antibodies to purified house dust mite allergens Der fI and Der fII in nasal secretions have never been documented. Therefore, we determined specific IgA, SIgA and IgG antibodies (abs) to crude extract of D. farinae and its purified allergens Der fI and der f II in nasal secretions collected by aspiration from 34 normal subjects, 25 untreated nasal allergic patients and 28 treated nasal allergic patients on parenteral immunotherapy by means of an avidin-biotin ELISA. The following results were obtained. (1) The specific IgA, SIgA and IgG abs to each of the three kinds of allergens correlated with each other. The groups of patients with nasal allergy (both treated and untreated) showed higher levels of specific IgA, SIgA and IgG abs to the allergens than the normal group. (2) In the group of treated patients, the levels of specific abs were not correlated with the clinical improvement of symptoms or the degree of response to nasal challenge. (3) The treated patients failed to show significantly higher levels of abs in nasal secretions than the untreated patients. (4) The specific IgA and SIgA abs in nasal secretions seemed to be predominantly produced locally, and IgG abs might be transudated from the circulation.
- Published
- 1994
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