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527 results on '"Xiao, Yuling"'

13. Clonal Dissemination of Antifungal-Resistant Candida haemulonii, China

Author

Chen, Xinfei, Jia, Xinmiao, Bing, Jian, Zhang, Han, Hong, Nan, Liu, Yun, Xi, Haiyang, Wang, Weiping, Liu, Zhiyong, Zhang, Qiangqiang, Li, Li, Kang, Mei, Xiao, Yuling, Yang, Bin, Lin, Yulan, Xu, Hui, Fan, Xin, Huang, Jingjing, Gong, Jie, Xu, Juan, Xie, Xiuli, Yang, Wenhang, Zhang, Ge, Zhang, Jingjia, Kang, Wei, Wang, He, Hou, Xin, Xiao, Meng, and Xu, Yingchun

Subjects
Drug resistance in microorganisms -- Genetic aspects, Candida -- Distribution -- Identification and classification -- Genetic aspects, Company distribution practices, Health
Abstract

The first case of human infection caused by the yeast Candida haemulonii was reported in 1984 (1). Recent research has indicated that the previously recognized C. haemulonii species is actually [...]

Published
2023
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20. New research advances and future prospect in precision treatment of triple-negative breast cancer

Author

XIAO Yuling, ZHU Xiuzhi, JIANG Yizhou, SHAO Zhimin

Subjects
triple-negative breast cancer, molecular subtypes, precision therapy, targeted therapy, immunotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

According to the latest data released by the Cancer Research Institute of the World Health Organization, breast cancer has replaced lung cancer as the malignant tumor with the highest incidence rate in the world. Triple-negative breast cancer (TNBC) is defined by a lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). Compared with other types of breast cancer, TNBC bears the characteristics of high metastasis rate, strong invasiveness and poor prognosis. TNBC is not sensitive to endocrine therapy and anti-HER2 therapy, and chemotherapy is its main systemic treatment. With the vigorous development of genomics, transcriptomics, metabolomics, proteomics, microbiomics technologies and the in-depth study of TNBC molecular subtyping, targeted therapy and immunotherapy drugs, including poly(ADP-ribose) polymerase (PARP) inhibitors, trophoblast cell-surface antigen 2 (TROP-2) antibody-drug conjugate, pembrolizumab, atezolizumab, durvalumab, etc., have provided new therapeutic methods, which are changing the clinical practice and treatment pattern of TNBC. It is believed accurate therapy will become a new direction of development in the future. Based on the molecular subtypes of TNBC, here we summarized the research advances in targeted therapy and immunotherapy of TNBC, in order to provide reference for the precise treatment strategy of TNBC in the future.

Published
2022
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27. Nanodelivery of nucleic acids

Author

Mendes, Bárbara B., Conniot, João, Avital, Aviram, Yao, Dongbao, Jiang, Xingya, Zhou, Xiang, Sharf-Pauker, Noga, Xiao, Yuling, Adir, Omer, Liang, Haojun, Shi, Jinjun, Schroeder, Avi, and Conde, João

Published
2022
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35. Field-Deployable Colorimetric Array for On-Site Diagnosis of Urinary Tract Infection and Identification of Causative Pathogens

Author

Li, Xianming, Zheng, Ting, Xiao, Yuling, Zhao, Yi, and Wu, Peng

Abstract

Urinary tract infection (UTI) is a common and prevalent disease caused by a spectrum of pathogens. Lack of access to rapid, portable, and high-quality diagnostics in resource-limited settings aggravates the improper treatment of UTIs, which is also a major driver of antibiotic misuse worldwide. Here, we describe a custom-made portable colorimetric array (PoCA) for reading out polymerase chain reaction (PCR) amplicons, the rationale of which is to transfer the previously developed dsDNA-based photosensitization colorimetric assay (solution) onto paper discs for detection. By integrating mini-LED irradiation and paper discs, the PoCA can read out 96 PCR tests in one pot, thus allowing diagnosis and identification of 12 prevailing UTI pathogens in less than 2 h, coupled with a portable thermal cycler for PCR. After analyzing 200 clinical urine samples, the pathogen profiling accuracy of the PoCA was demonstrated to be higher than the standard urine culture (confirmed with metagenomic next-generation sequencing). The PoCA platform could be used in primary care for rapid UTI diagnosis and pathogen identification.

Published
2024
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46. The Subway Pantograph Detection Using Modified Faster R-CNN

Author

Ge, Ruimin, Zhu, Yu, Xiao, Yuling, Chen, Zhihua, Diniz Junqueira Barbosa, Simone, Series editor, Chen, Phoebe, Series editor, Du, Xiaoyong, Series editor, Filipe, Joaquim, Series editor, Kara, Orhun, Series editor, Kotenko, Igor, Series editor, Liu, Ting, Series editor, Sivalingam, Krishna M., Series editor, Washio, Takashi, Series editor, Yang, Xiaokang, editor, and Zhai, Guangtao, editor

Published
2017
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